Resistance of Fc receptor-deficient mice to fatal glomerulonephritis

Journal of Clinical Investigation

Volumn 102, Issue 6, 1998, Pages 1229-1238

  Park, Seung Yong ^a   Ueda, Shiro ^b   Ohno, Hiroshi ^a   Hamano, Yuki ^a   Tanaka, Misaki ^c   Shiratori, Tooru ^a   Yamazaki, Tetsuo ^a   Arase, Hisashi ^a   Arase, Noriko ^a   Karasawa, Akira ^d   Sato, Soichiro ^d   Ledermann, Birgit ^e   Kondo, Yoichiro ^a   Okumura, Ko ^c   Ra, Chisel ^c   Saito, Takashi ^a  

^a CHIBA UNIVERSITY   (Japan)

^b Lab Molec Biol Biotech Res C   (Japan)

^c JUNTENDO UNIVERSITY   (Japan)

^d KYOWA HAKKO KOGYO CO LTD   (Japan)

^e Preclinical Research   (Switzerland)

Author keywords

Anti GBM antibody; Fc receptor; Glomerulonephritis; Knockout mouse; Masugi nephritis

Indexed keywords

FC RECEPTOR; GLOMERULUS BASEMENT MEMBRANE ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; DISEASE RESISTANCE; FATALITY; FEMALE; GLOMERULONEPHRITIS; HYPERNATREMIA; IMMUNE COMPLEX DEPOSITION; IMMUNE COMPLEX NEPHRITIS; KNOCKOUT MOUSE; MALE; MASUGI NEPHRITIS; NONHUMAN; PRIORITY JOURNAL;

EID: 17944384552     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI3256     Document Type: Article

References (39)

1. Takai, T., M. Li, D. Sylvestre, R. Clynes, and J.F. Ravetch. 1994. FcRγ chain deletion results in pleiotropic effector cell defects. Cell. 75:519-529.
2. Clynes, R., and J. V. Ravetch. 1995. Cytotoxic antibodies trigger inflammation through Fc receptors. Immunity. 3:21-26.
3. Hazenbos, W.L.W., J.E. Gessner, F.M.A. Hofhuis, H. Kuipers, D. Meyer, I.A.F.M. Heijnen, R.E. Schmidt, M. Sandor, P.J.A. Capel, M. Daëron, et al. 1996. Impaired IgG-dependent anaphylaxis and Arthus reaction in FcγRIII (CD16) deficient mice. Immunity. 5:181-188.
4. Sylvestre, D.L., and J.V. Ravetch. 1996. A dominant role for mast cell Fc receptors in the Arthus reaction. Immunity. 5:387-390.
5. Sylvestre, D., R. Clynes, M. Ma, H. Warren, M.C. Carroll, and J.V. Ravetch. 1996. Immunoglobulin G-mediated inflammatory responses develop normally in complement-deficient mice. J. Exp. Med 184:2385-2392.
6. Ravetch, J.V. 1994. Fc receptors: rubor redux. Cell. 78:553-560.
7. Deo, Y.M., R.F. Graziano, R. Repp, and J.G.J. van de Winkel. 1997. Clinical significance of IgG Fc receptors and FcγR-directed immunotherapies. Immunol. Today. 18:127-135.
8. Daëron, M. 1997. Fc receptor biology. Annu. Rev. Immunol. 15:203-234.
9. Wilson, C.B., and F.J. Dixon. 1991. The renal response to immunological injury. In The Kidney. B.M. Brenner and F.C. Rector. Jr., editors. W.B. Saunders, Philadelphia. 1062-1181.
10. Couser, W.G. 1985. Mechanism of glomerular injury in immune complex diseases. Kidney Int. 28:569-583.
11. Masugi, M. 1933. Über das Wesen der spezifischen Veränderungen der Niere und der Leber durch das Nephrotoxin bzw. das Hepatotoxin. Zugleich ein Beitrag zur Pathogenese der Glomerulonephritis und der eklamptischen Leher Erkrankung. Beitr. path. Anat. 91:82-112.
12. Lerner, R.A., R.J. Glassock, and F.J. Dixon. 1967. The role of antiglomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. J. Exp Med 126:989-1004.
13. Couser, W.O., C. Darby, D.J. Salant, S. Adler, M.M. Stilmant, and L.M. Lowenstein. 1985. Anti-GBM antibody-induced proteinuria in isolated perfused rat kidney. Am. J. Physiol. 249:F241-F250.
14. Benoit, F.L., D.B. Rulon, G.B. Theil, P.D. Doolan, and R.H. Watten. 1964. Goodpasture's syndrome. A clinicopathologic entity. Am. J. Med. 37:424-444.
15. Shigematsu, H. 1970. Glomerular events during the initial phase of rat Masugi nephritis. Virchows Arch. B. 5:187-200.
16. Unanue, E.R., and F.J. Dixon. 1967. Experimental glomerulonephritis: immunological events and pathogenetic mechanism. Adv. Immunol. 6:1-90.
17. Huang, X.-R., S.R. Holdsworth, and P.G. Tipping. 1994. Evidence for delayed-type hypersensitivity mechanism in glomerular crescent formation. Kidney Int. 46:69-78.
18. Huang, X.-R., P.G. Tipping, L. Shuo, and S.R. Holdsworth. 1997. Th1 responsiveness to nephritogenic antigens determines susceptibility to crescentic glomerulonephritis in mice. Kidney Int. 51:94-103.
19. Li. S., S.R. Holdsworth, and P.G. Tipping. 1997. Antibody independent crescentic glomerulonephritis in μ chain deficient mice. Kidney Int. 51:672-678.
20. Kalluri, R., T.M. Danoff, H. Okada, and E.G. Neilson. 1997. Susceptibility of anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice. J. Clin. Invest. 100:2263-2275.
21. Ra, C., M.-H.E. Jouvin, and J.-P. Kinet. 1989. Complete structure of the mouse mast cell receptor for IgE (FceRI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells. J. Biol. Chem. 264:15323-15327.
22. Thomas, K.R., and M.R. Capecchi. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell. 51:503-512.
23. Ledermann, B., and K. Bürki. 1991. Establishment of a germ-line competent C57BL/6 embryonic stem cell line. Exp. Cell Res. 197:254-258.
24. Ohno, H., T. Aoe, S. Taki, D. Kitamura, Y. Ishida, K. Rajewsky, and T. Saito. 1993. Developmental and functional impairment of T cells in mice lacking CD3ζ chains. EMBO (Eur. Mol. Biol. Organ.) J. 12:4357-4366.
25. +T cells upon NKR-P1 cross-linking. J. Exp. Med. 183:2391-2396.
26. Ono, S., H. Ohno, and T. Saito. 1995. Rapid turnover of the CD3ζ chain independent of the TCR-CD3 complex in normal T cells. Immunity. 2:639-644.
27. Ra, C., M.-H.E. Jouvin, U. Blank, and J.P. Kinet. 1989. A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical suhunit. Nature. 341:752-754.
28. Ernst, L.K., A.M. Duchemin, and C.L. Anderson. 1993. Association of the high-affinity receptor for IgG (FcγRI) with the γ subunit of the IgE receptor. Proc. Natl. Acad. Sci. USA. 90:6023-6027.
29. Hibbs, M.L., P. Servavaj, O. Carpen, T.A. Springer, H. Kuster, M.-H.E. Jouvin, and J.-P. Kinet. 1989. Mechanism for regulating expression of membrane isoforms of FcγRIII. Science. 246:1608-1611.
30. Wieslander, J., P. Bygren, and D. Heinegard. 1984. Isolation of the specific glomerular basement membrane antigen involved in Goodpasture syndrome. Proc. Natl. Acad. Sci. USA. 81:1544-1548.
31. Schrijver, G.S., M.J.J.T. Bodman, K.J.M. Assmann, R.M.W. de Waal, J.C.M. Robben, H. van Gasteren, and R.A.P. Koene. 1990. Anti-GBM nephritis in the mouse: role of granulocytes in the heterologous phase. Kidney Int. 38: 86-95.
32. Kondo, Y., H. Shigematsu, and Y. Kobayashi. 1972. Cellular aspects of rabbit Masugi nephritis. II. Progressive glomerular injuries with crescent formation. Lab. Invest. 27:620-631.
33. Koyama, A., M. Fujisaki, M. Kobayashi, M. Igarashi, and M. Narita. 1991. A glomerular permeability factor produced by human T cell hybridomas. Kidney Int. 40:453-460.
34. Feith, G.W., K.J.M. Assmann, M.J.J.T. Bogman, A.P.M. van Gompel, J. Schalkwijk, and R.A.P. Koene. 1996. Different mediator systems in biphasic heterologous phase of anti-GBM nephritis in mice. Nephrology Dial. Transplant. 11:599-607.
35. Feith, G.W., K.J.M. Assmann, M.J.J.T. Bogman, A.P.M. van Gompel. J. Schalkwijk, and R.A.P. Koene. 1993. Lack ot albuminuria in the early heterologous phase of anti-GBM nephritis in beige mice. Kidney Int. 43:824-827.
36. Clynes, R., C. Dumitru, and J.V. Ravetch. 1998. Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephrtis. Science. 279:1052-1054.
37. Fantone, J.C., and P.A. Ward. 1982. Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions. Am. J. Pathol. 107:397-418.
38. Johnson, R.J., D. Lovett, R.I. Lehrer, W.G. Couser, and S.J. Klebanoff. 1994. Role of oxidants and proteases in glomerular injury. Kidney Int. 45:352-359.
39. Shah, S.V. 1989. Role of reactive oxygen metabolites in experimental glomerular disease. Kidney Int. 35:1093-1106.