Role of ELA region in auto-activation of mutant KIT receptor: A molecular dynamics simulation insight

Journal of Biomolecular Structure and Dynamics

Volumn 32, Issue 7, 2014, Pages 1033-1046

  Purohit, Rituraj ^a,b  

^a Human Genetics Foundation   (Italy)

^b VIT UNIVERSITY   (India)

Author keywords

A loop region; GIST; KIT receptor; molecular dynamics simulation

Indexed keywords

KIT RECEPTOR; ONCOPROTEIN; PHOSPHOTRANSFERASE; SUNITINIB; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; PYRROLE DERIVATIVE; STEM CELL FACTOR RECEPTOR;

ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; ENZYME CONFORMATION; EXTENDED A LOOP REGION; GAIN OF FUNCTION MUTATION; GASTROINTESTINAL STROMAL TUMOR; HYDROGEN BOND; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; CHEMISTRY; DRUG RESISTANCE; HUMAN; MUTATION; PROTEIN TERTIARY STRUCTURE;

ANTINEOPLASTIC AGENTS; DRUG RESISTANCE, NEOPLASM; HUMANS; HYDROGEN BONDING; INDOLES; MOLECULAR DYNAMICS SIMULATION; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-KIT; PYRROLES;

EID: 84899920528     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2013.803264     Document Type: Article

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