Structure of a c-Kit product complex reveals the basis for kinase transactivation

Journal of Biological Chemistry

Volumn 278, Issue 34, 2003, Pages 31461-31464

  Mol, Clifford D ^b   Lim, Kheng B ^b   Sridhar, Vandana ^b   Zou, Hua ^b   Chien, Ellen Y T ^b   Sang, Bi Ching ^b   Nowakowski, Jacek ^b   Kassel, Daniel B ^b   Cronin, Ciarán N ^b   McRee, Duncan E ^a  

^a Takeda San Diego Inc   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHEMOTHERAPY; CRYSTAL STRUCTURE; DIMERS; GASTROENTEROLOGY; MUTAGENESIS; TUMORS;

MALIGNANT HUMAN CANCERS;

ENZYMES;

GENE PRODUCT; IMATINIB; PHOSPHATE; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STEM CELL FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; CARCINOGENESIS; COMPETITIVE INHIBITION; COMPLEX FORMATION; DIMERIZATION; DRUG DESIGN; DRUG TARGETING; ENZYME ACTIVATION; GASTROINTESTINAL TUMOR; GENE EXPRESSION; GENE FUNCTION; GENE STRUCTURE; HUMAN; LIGAND BINDING; MAST CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; PROTO ONCOGENE; TRANSACTIVATION;

CHROMATOGRAPHY, LIQUID; DIMERIZATION; HUMANS; MASS SPECTROMETRY; PHOSPHORYLATION; PHOSPHOTRANSFERASES; PROTEIN CONFORMATION; PROTO-ONCOGENE PROTEINS C-KIT; TRANS-ACTIVATION (GENETICS);

EID: 0042357240     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300186200     Document Type: Article

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