Characterization of timed changes in hepatic copper concentrations, Methionine metabolism, gene expression, and global DNA Methylation in the Jackson toxic milk mouse model of Wilson disease

International Journal of Molecular Sciences

Volumn 15, Issue 5, 2014, Pages 8004-8023

  Le, Anh ^a   Shibata, Noreene M ^a   French, Samuel W ^b   Kim, Kyoungmi ^c   Kharbanda, Kusum K ^d   Islam, Mohammad S ^c   Lasalle, Janine M ^c   Halsted, Charles H ^a   Keen, Carl L ^a   Medici, Valentina ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARBOR UCLA MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

Author keywords

Copper; DNA; Gene expression; Methylation; Wilson disease

Indexed keywords

COPPER; IRON; METHIONINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; ELECTRON MICROSCOPY; ENZYME ACTIVITY; FETUS; GEL BLOT ANALYSIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENOTYPE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID METABOLISM; LIVER HISTOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; WILSON DISEASE; ANIMAL; BODY WEIGHT; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; LIVER; METABOLISM; PATHOLOGY;

ANIMALS; BODY WEIGHT; COPPER; DISEASE MODELS, ANIMAL; DNA METHYLATION; GENE EXPRESSION REGULATION; HEPATOLENTICULAR DEGENERATION; LIPID METABOLISM; LIVER; METHIONINE; MICE;

EID: 84899917266     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms15058004     Document Type: Article

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