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Volumn 5, Issue 1, 2013, Pages 193-199

Nutrition in pregnancy: The argument for including a source of choline

Author keywords

Birth defects; Brain development; Choline; Liver function; Placenta; Pregnancy

Indexed keywords

CHOLINE;

EID: 84876563573     PISSN: None     EISSN: 11791411     Source Type: Journal    
DOI: 10.2147/IJWH.S36610     Document Type: Article
Times cited : (72)

References (72)
  • 2
    • 33750107341 scopus 로고    scopus 로고
    • Choline: Critical role during fetal development and dietary requirements in adults
    • Zeisel SH. Choline: critical role during fetal development and dietary requirements in adults. Annu Rev Nutr. 2006;26:229-250.
    • (2006) Annu Rev Nutr. , vol.26 , pp. 229-250
    • Zeisel, S.H.1
  • 3
    • 0038333251 scopus 로고    scopus 로고
    • Concentrations of choline-containing compounds and betaine in common foods
    • Zeisel SH, Mar MH, Howe JC, Holden JM. Concentrations of choline-containing compounds and betaine in common foods. J Nutr. 2003;133(5):1302-1307.
    • (2003) J Nutr. , vol.133 , Issue.5 , pp. 1302-1307
    • Zeisel, S.H.1    Mar, M.H.2    Howe, J.C.3    Holden, J.M.4
  • 4
    • 3242698799 scopus 로고    scopus 로고
    • Periconceptional dietary intake of choline and betaine and neural tube defects in offspring
    • Shaw GM, Carmichael SL, Yang W, Selvin S, Schaffer DM. Periconceptional dietary intake of choline and betaine and neural tube defects in offspring. Am J Epidemiol. 2004;160(2):102-109.
    • (2004) Am J Epidemiol. , vol.160 , Issue.2 , pp. 102-109
    • Shaw, G.M.1    Carmichael, S.L.2    Yang, W.3    Selvin, S.4    Schaffer, D.M.5
  • 5
    • 33646710996 scopus 로고    scopus 로고
    • Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study
    • Cho E, Zeisel SH, Jacques P, etal. Dietary choline and betaine assessed by food-frequency questionnaire in relation to plasma total homocysteine concentration in the Framingham Offspring Study. Am J Clin Nutr. 2006;83(4):905-911.
    • (2006) Am J Clin Nutr. , vol.83 , Issue.4 , pp. 905-911
    • Cho, E.1    Zeisel, S.H.2    Jacques, P.3
  • 6
    • 34547750947 scopus 로고    scopus 로고
    • Usual choline and betaine dietary intake and incident coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
    • Bidulescu A, Chambless LE, Siega-Riz AM, Zeisel SH, Heiss G. Usual choline and betaine dietary intake and incident coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Cardiovasc Disord. 2007;7:20.
    • (2007) BMC Cardiovasc Disord. , vol.7 , pp. 20
    • Bidulescu, A.1    Chambless, L.E.2    Siega-Riz, A.M.3    Zeisel, S.H.4    Heiss, G.5
  • 7
    • 62149099618 scopus 로고    scopus 로고
    • Repeatability and measurement error in the assessment of choline and betaine dietary intake: The Atherosclerosis Risk in Communities (ARIC) study
    • Bidulescu A, Chambless LE, Siega-Riz AM, Zeisel SH, Heiss G. Repeatability and measurement error in the assessment of choline and betaine dietary intake: the Atherosclerosis Risk in Communities (ARIC) study. Nutr J. 2009;8:14.
    • (2009) Nutr J. , vol.8 , pp. 14
    • Bidulescu, A.1    Chambless, L.E.2    Siega-Riz, A.M.3    Zeisel, S.H.4    Heiss, G.5
  • 8
    • 34548160517 scopus 로고    scopus 로고
    • Dietary choline and betaine and the risk of distal colorectal adenoma in women
    • Cho E, Willett WC, Colditz GA, etal. Dietary choline and betaine and the risk of distal colorectal adenoma in women. J Natl Cancer Inst. 2007;99(16):1224-1231.
    • (2007) J Natl Cancer Inst. , vol.99 , Issue.16 , pp. 1224-1231
    • Cho, E.1    Willett, W.C.2    Colditz, G.A.3
  • 10
    • 84862536855 scopus 로고    scopus 로고
    • An introduction to the nutrition and metabolism of choline
    • Hollenbeck CB. An introduction to the nutrition and metabolism of choline. Cent Nerv Syst Agents Med Chem. 2012;12(2):100-113.
    • (2012) Cent Nerv Syst Agents Med Chem. , vol.12 , Issue.2 , pp. 100-113
    • Hollenbeck, C.B.1
  • 11
    • 0028894492 scopus 로고
    • Molecular basis of osmotic regulation
    • Burg M. Molecular basis of osmotic regulation. Am J Physiol. 1995;268(6 Pt 2):F983-F996.
    • (1995) Am J Physiol. , vol.268 , Issue.6 PART 2
    • Burg, M.1
  • 12
    • 77955781541 scopus 로고    scopus 로고
    • Deletion of murine choline dehydrogenase results in diminished sperm motility
    • Johnson AR, Craciunescu CN, Guo Z, etal. Deletion of murine choline dehydrogenase results in diminished sperm motility. FASEB J. 2010;24(8):2752-2761.
    • (2010) FASEB J. , vol.24 , Issue.8 , pp. 2752-2761
    • Johnson, A.R.1    Craciunescu, C.N.2    Guo, Z.3
  • 13
    • 80054691714 scopus 로고    scopus 로고
    • Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas
    • Teng YW, Mehedint MG, Garrow TA, Zeisel SH. Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. J Biol Chem. 2011;286(42):36258-36267.
    • (2011) J Biol Chem. , vol.286 , Issue.42 , pp. 36258-36267
    • Teng, Y.W.1    Mehedint, M.G.2    Garrow, T.A.3    Zeisel, S.H.4
  • 14
    • 0017291039 scopus 로고
    • Brain acetylcholine: Control by dietary choline
    • Cohen EL, Wurtman RJ. Brain acetylcholine: control by dietary choline. Science. 1976;191(4227):561-562.
    • (1976) Science. , vol.191 , Issue.4227 , pp. 561-562
    • Cohen, E.L.1    Wurtman, R.J.2
  • 15
    • 0000244714 scopus 로고
    • Effect of chronic choline deficiency in rats on liver folate content and distribution
    • Varela-Moreiras G, Selhub J, da Costa K, Zeisel SH. Effect of chronic choline deficiency in rats on liver folate content and distribution. J Nutr Biochem. 1992;3:519-522.
    • (1992) J Nutr Biochem. , vol.3 , pp. 519-522
    • Varela-Moreiras, G.1    Selhub, J.2    da Costa, K.3    Zeisel, S.H.4
  • 16
    • 0026027663 scopus 로고
    • Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution
    • Selhub J, Seyoum E, Pomfret EA, Zeisel SH. Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution. Cancer Res. 1991;51(1):16-21.
    • (1991) Cancer Res. , vol.51 , Issue.1 , pp. 16-21
    • Selhub, J.1    Seyoum, E.2    Pomfret, E.A.3    Zeisel, S.H.4
  • 17
    • 77951458462 scopus 로고    scopus 로고
    • Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men
    • Shin W, Yan J, Abratte CM, Vermeylen F, Caudill MA. Choline intake exceeding current dietary recommendations preserves markers of cellular methylation in a genetic subgroup of folate-compromised men. J Nutr. 2010;140(5):975-980.
    • (2010) J Nutr. , vol.140 , Issue.5 , pp. 975-980
    • Shin, W.1    Yan, J.2    Abratte, C.M.3    Vermeylen, F.4    Caudill, M.A.5
  • 18
    • 0025729745 scopus 로고
    • Choline, an essential nutrient for humans
    • Zeisel SH, Da Costa KA, Franklin PD, etal. Choline, an essential nutrient for humans. FASEB J. 1991;5(7):2093-2098.
    • (1991) FASEB J. , vol.5 , Issue.7 , pp. 2093-2098
    • Zeisel, S.H.1    da Costa, K.A.2    Franklin, P.D.3
  • 19
    • 78149250549 scopus 로고    scopus 로고
    • Dietary choline requirements of women: Effects of estrogen and genetic variation
    • Fischer LM, da Costa KA, Kwock L, Galanko J, Zeisel SH. Dietary choline requirements of women: effects of estrogen and genetic variation. Am J Clin Nutr. 2010;92(5):1113-1119.
    • (2010) Am J Clin Nutr. , vol.92 , Issue.5 , pp. 1113-1119
    • Fischer, L.M.1    da Costa, K.A.2    Kwock, L.3    Galanko, J.4    Zeisel, S.H.5
  • 20
    • 34248348719 scopus 로고    scopus 로고
    • Sex and menopausal status influence human dietary requirements for the nutrient choline
    • Fischer LM, daCosta K, Kwock L, etal. Sex and menopausal status influence human dietary requirements for the nutrient choline. Am J Clin Nutr. 2007;85(5):1275-1285.
    • (2007) Am J Clin Nutr. , vol.85 , Issue.5 , pp. 1275-1285
    • Fischer, L.M.1    daCosta, K.2    Kwock, L.3
  • 21
    • 3042696730 scopus 로고    scopus 로고
    • Elevated serum creatine phosphokinase in choline-deficient humans: Mechanistic studies in C2C12mouse myoblasts
    • da Costa KA, Badea M, Fischer LM, Zeisel SH. Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12mouse myoblasts. Am J Clin Nutr. 2004;80(1):163-170.
    • (2004) Am J Clin Nutr. , vol.80 , Issue.1 , pp. 163-170
    • da Costa, K.A.1    Badea, M.2    Fischer, L.M.3    Zeisel, S.H.4
  • 22
    • 0034870968 scopus 로고    scopus 로고
    • Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: Proof of a human choline requirement: A placebo-controlled trial
    • Buchman AL, Ament ME, Sohel M, etal. Choline deficiency causes reversible hepatic abnormalities in patients receiving parenteral nutrition: proof of a human choline requirement: a placebo-controlled trial. JPEN J Parenter Enteral Nutr. 2001;25(5):260-268.
    • (2001) JPEN J Parenter Enteral Nutr. , vol.25 , Issue.5 , pp. 260-268
    • Buchman, A.L.1    Ament, M.E.2    Sohel, M.3
  • 23
    • 0038159461 scopus 로고    scopus 로고
    • A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice
    • Noga AA, Vance DE. A gender-specific role for phosphatidylethanolamine N-methyltransferase-derived phosphatidylcholine in the regulation of plasma high density and very low density lipoproteins in mice. J Biol Chem. 2003;278(24):21851-21859.
    • (2003) J Biol Chem. , vol.278 , Issue.24 , pp. 21851-21859
    • Noga, A.A.1    Vance, D.E.2
  • 26
    • 0029985230 scopus 로고    scopus 로고
    • Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture
    • Albright CD, Lui R, Bethea TC, Da Costa KA, Salganik RI, Zeisel SH. Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. FASEB J. 1996;10(4):510-516.
    • (1996) FASEB J. , vol.10 , Issue.4 , pp. 510-516
    • Albright, C.D.1    Lui, R.2    Bethea, T.C.3    da Costa, K.A.4    Salganik, R.I.5    Zeisel, S.H.6
  • 27
    • 0035798703 scopus 로고    scopus 로고
    • Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB
    • Holmes-McNary MQ, Baldwin AS Jr, Zeisel SH. Opposing regulation of choline deficiency-induced apoptosis by p53 and nuclear factor kappaB. J Biol Chem. 2001;276(44):41197-41204.
    • (2001) J Biol Chem. , vol.276 , Issue.44 , pp. 41197-41204
    • Holmes-McNary, M.Q.1    Baldwin Jr., A.S.2    Zeisel, S.H.3
  • 28
    • 84860391782 scopus 로고    scopus 로고
    • A novel cause for abnormal liver function tests in pregnancy and the puerperium: Non-alcoholic fatty liver disease
    • Page LM, Girling JC. A novel cause for abnormal liver function tests in pregnancy and the puerperium: non-alcoholic fatty liver disease. BJOG. 2011;118(12):1532-1535.
    • (2011) BJOG. , vol.118 , Issue.12 , pp. 1532-1535
    • Page, L.M.1    Girling, J.C.2
  • 29
    • 84875714410 scopus 로고    scopus 로고
    • Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis
    • In press
    • Corbin KD, Abdelmalek MF, Spencer MD, et al. Genetic signatures in choline and 1-carbon metabolism are associated with the severity of hepatic steatosis. FASEB J. In press 2013.
    • (2013) FASEB J.
    • Corbin, K.D.1    Abdelmalek, M.F.2    Spencer, M.D.3
  • 30
    • 34249668818 scopus 로고    scopus 로고
    • Epidemiology and natural history of NAFLD and NASH
    • Ong JP, Younossi ZM. Epidemiology and natural history of NAFLD and NASH. Clin Liver Dis. 2007;11(1):1-16, vii.
    • (2007) Clin Liver Dis. , vol.11 , Issue.1
    • Ong, J.P.1    Younossi, Z.M.2
  • 31
    • 84858072223 scopus 로고    scopus 로고
    • Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression
    • Corbin KD, Zeisel SH. Choline metabolism provides novel insights into nonalcoholic fatty liver disease and its progression. Curr Opin Gastroenterol. 2012;28(2):159-165.
    • (2012) Curr Opin Gastroenterol. , vol.28 , Issue.2 , pp. 159-165
    • Corbin, K.D.1    Zeisel, S.H.2
  • 32
    • 84876590386 scopus 로고    scopus 로고
    • A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1)
    • November 29,
    • Jiang X, Bar HY, Yan J, etal. A higher maternal choline intake among third-trimester pregnant women lowers placental and circulating concentrations of the antiangiogenic factor fms-like tyrosine kinase-1 (sFLT1). FASEB J. Epub November 29, 2012.
    • (2012) FASEB J. Epub
    • Jiang, X.1    Bar, H.Y.2    Yan, J.3
  • 33
    • 84864772359 scopus 로고    scopus 로고
    • Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans
    • Jiang X, Yan J, West AA, etal. Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans. FASEB J. 2012;26(8):3563-3574.
    • (2012) FASEB J. , vol.26 , Issue.8 , pp. 3563-3574
    • Jiang, X.1    Yan, J.2    West, A.A.3
  • 35
    • 0242661101 scopus 로고    scopus 로고
    • Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus
    • Craciunescu CN, Albright CD, Mar MH, Song J, Zeisel SH. Choline availability during embryonic development alters progenitor cell mitosis in developing mouse hippocampus. J Nutr. 2003;133(11):3614-3618.
    • (2003) J Nutr. , vol.133 , Issue.11 , pp. 3614-3618
    • Craciunescu, C.N.1    Albright, C.D.2    Mar, M.H.3    Song, J.4    Zeisel, S.H.5
  • 36
    • 34247196759 scopus 로고    scopus 로고
    • Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats
    • Glenn MJ, Gibson EM, Kirby ED, Mellott TJ, Blusztajn JK, Williams CL. Prenatal choline availability modulates hippocampal neurogenesis and neurogenic responses to enriching experiences in adult female rats. Eur J Neurosci. 2007;25(8):2473-2482.
    • (2007) Eur J Neurosci. , vol.25 , Issue.8 , pp. 2473-2482
    • Glenn, M.J.1    Gibson, E.M.2    Kirby, E.D.3    Mellott, T.J.4    Blusztajn, J.K.5    Williams, C.L.6
  • 37
    • 0023910197 scopus 로고
    • Pre-and postnatal choline supplementation produces long-term facilitation of spatial memory
    • Meck WH, Smith RA, Williams CL. Pre-and postnatal choline supplementation produces long-term facilitation of spatial memory. Dev Psychobiol. 1988;21(4):339-353.
    • (1988) Dev Psychobiol. , vol.21 , Issue.4 , pp. 339-353
    • Meck, W.H.1    Smith, R.A.2    Williams, C.L.3
  • 38
    • 0031945496 scopus 로고    scopus 로고
    • Prenatal choline supplementation decreases the threshold for induction of long-term potentiation in young adult rats
    • Pyapali GK, Turner DA, Williams CL, Meck WH, Swartzwelder HS. Prenatal choline supplementation decreases the threshold for induction of long-term potentiation in young adult rats. J Neurophysiol. 1998;79(7):1790-1796.
    • (1998) J Neurophysiol. , vol.79 , Issue.7 , pp. 1790-1796
    • Pyapali, G.K.1    Turner, D.A.2    Williams, C.L.3    Meck, W.H.4    Swartzwelder, H.S.5
  • 39
    • 53149102838 scopus 로고    scopus 로고
    • Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats
    • Glenn MJ, Kirby ED, Gibson EM, etal. Age-related declines in exploratory behavior and markers of hippocampal plasticity are attenuated by prenatal choline supplementation in rats. Brain Res. 2008;1237:110-123.
    • (2008) Brain Res. , vol.1237 , pp. 110-123
    • Glenn, M.J.1    Kirby, E.D.2    Gibson, E.M.3
  • 40
    • 82355188293 scopus 로고    scopus 로고
    • The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort
    • Poly C, Massaro JM, Seshadri S, etal. The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort. Am J Clin Nutr. 2011;94(6):1584-1591.
    • (2011) Am J Clin Nutr. , vol.94 , Issue.6 , pp. 1584-1591
    • Poly, C.1    Massaro, J.M.2    Seshadri, S.3
  • 41
    • 84869765864 scopus 로고    scopus 로고
    • Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: A randomized, double-blind, placebo-controlled trial
    • Cheatham CL, Goldman BD, Fischer LM, da Costa KA, Reznick JS, Zeisel SH. Phosphatidylcholine supplementation in pregnant women consuming moderate-choline diets does not enhance infant cognitive function: a randomized, double-blind, placebo-controlled trial. Am J Clin Nutr. 2012;96(6):1465-1472.
    • (2012) Am J Clin Nutr. , vol.96 , Issue.6 , pp. 1465-1472
    • Cheatham, C.L.1    Goldman, B.D.2    Fischer, L.M.3    da Costa, K.A.4    Reznick, J.S.5    Zeisel, S.H.6
  • 42
    • 16844384130 scopus 로고    scopus 로고
    • A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: Clarification of the 1996 institute of medicine criteria
    • Hoyme HE, May PA, Kalberg WO, etal. A practical clinical approach to diagnosis of fetal alcohol spectrum disorders: clarification of the 1996 institute of medicine criteria. Pediatrics. 2005;115(1):39-47.
    • (2005) Pediatrics. , vol.115 , Issue.1 , pp. 39-47
    • Hoyme, H.E.1    May, P.A.2    Kalberg, W.O.3
  • 43
    • 79952198463 scopus 로고    scopus 로고
    • Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats
    • Thomas JD, Idrus NM, Monk BR, Dominguez HD. Prenatal choline supplementation mitigates behavioral alterations associated with prenatal alcohol exposure in rats. Birth Defects Res A Clin Mol Teratol. 2010;88(10):827-837.
    • (2010) Birth Defects Res A Clin Mol Teratol. , vol.88 , Issue.10 , pp. 827-837
    • Thomas, J.D.1    Idrus, N.M.2    Monk, B.R.3    Dominguez, H.D.4
  • 44
    • 69549121616 scopus 로고    scopus 로고
    • Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats
    • Thomas JD, Abou EJ, Dominguez HD. Prenatal choline supplementation mitigates the adverse effects of prenatal alcohol exposure on development in rats. Neurotoxicol Teratol. 2009;31(5):303-311.
    • (2009) Neurotoxicol Teratol. , vol.31 , Issue.5 , pp. 303-311
    • Thomas, J.D.1    Abou, E.J.2    Dominguez, H.D.3
  • 45
    • 33847276614 scopus 로고    scopus 로고
    • Choline supplementation following third-trimester-equivalent alcohol exposure attenuates behavioral alterations in rats
    • Thomas JD, Biane JS, O'Bryan KA, O'Neill TM, Dominguez HD. Choline supplementation following third-trimester-equivalent alcohol exposure attenuates behavioral alterations in rats. Behav Neurosci. 2007;121(1):120-130.
    • (2007) Behav Neurosci. , vol.121 , Issue.1 , pp. 120-130
    • Thomas, J.D.1    Biane, J.S.2    O'Bryan, K.A.3    O'Neill, T.M.4    Dominguez, H.D.5
  • 46
    • 0000226495 scopus 로고
    • The biosynthesis of choline and its relation to phospholipid metabolism
    • Bremer J, Figard PH, Greenberg DM. The biosynthesis of choline and its relation to phospholipid metabolism. Biochim Biophys Acta. 1960;43:477-488.
    • (1960) Biochim Biophys Acta. , vol.43 , pp. 477-488
    • Bremer, J.1    Figard, P.H.2    Greenberg, D.M.3
  • 47
    • 70349178691 scopus 로고    scopus 로고
    • United States Department of Agriculture, Available from, Assessed March 10,2013
    • United States Department of Agriculture. USDA Database for the Choline Content of Common Foods, Release 2 (2008). Available from: http://www.ars.usda.gov/Services/docs.htm?docid=6232). Assessed March 10,2013.
    • (2008) USDA Database for the Choline Content of Common Foods, Release , vol.2
  • 48
    • 34547782307 scopus 로고    scopus 로고
    • Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes
    • Resseguie M, Song J, Niculescu MD, da Costa KA, Randall TA, Zeisel SH. Phosphatidylethanolamine N-methyltransferase (PEMT) gene expression is induced by estrogen in human and mouse primary hepatocytes. FASEB J. 2007;21(10):2622-2632.
    • (2007) FASEB J. , vol.21 , Issue.10 , pp. 2622-2632
    • Resseguie, M.1    Song, J.2    Niculescu, M.D.3    da Costa, K.A.4    Randall, T.A.5    Zeisel, S.H.6
  • 49
    • 79251524576 scopus 로고    scopus 로고
    • MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline
    • Yan J, Wang W, Gregory JF 3rd, etal. MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline. Am J Clin Nutr. 2011;93(2):348-355.
    • (2011) Am J Clin Nutr. , vol.93 , Issue.2 , pp. 348-355
    • Yan, J.1    Wang, W.2    Gregory III, J.F.3
  • 50
    • 79961116632 scopus 로고    scopus 로고
    • Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice
    • Chew TW, Jiang X, Yan J, etal. Folate intake, MTHFR genotype, and sex modulate choline metabolism in mice. J Nutr. 2011;141(8):1475-1481.
    • (2011) J Nutr. , vol.141 , Issue.8 , pp. 1475-1481
    • Chew, T.W.1    Jiang, X.2    Yan, J.3
  • 51
    • 0022270891 scopus 로고
    • Characterization of choline transport at maternal and fetal interfaces of the perfused guinea-pig placenta
    • Sweiry JH, Yudilevich DL. Characterization of choline transport at maternal and fetal interfaces of the perfused guinea-pig placenta. J Physiol. 1985;366:251-266.
    • (1985) J Physiol. , vol.366 , pp. 251-266
    • Sweiry, J.H.1    Yudilevich, D.L.2
  • 52
    • 0017250714 scopus 로고
    • Studies on accumulation and metabolic fate of (N-Me3H)choline in human term placenta fragments
    • Welsch F. Studies on accumulation and metabolic fate of (N-Me3H)choline in human term placenta fragments. Biochem Pharmacol. 1976;25(9):1021-1030.
    • (1976) Biochem Pharmacol. , vol.25 , Issue.9 , pp. 1021-1030
    • Welsch, F.1
  • 53
    • 0019881789 scopus 로고
    • Developmental changes in rat blood choline concentration
    • Zeisel SH, Wurtman RJ. Developmental changes in rat blood choline concentration. Biochem J. 1981;198(3):565-570.
    • (1981) Biochem J. , vol.198 , Issue.3 , pp. 565-570
    • Zeisel, S.H.1    Wurtman, R.J.2
  • 54
    • 0019223753 scopus 로고
    • Elevated choline concentration in neonatal plasma
    • Zeisel SH, Epstein MF, Wurtman RJ. Elevated choline concentration in neonatal plasma. Life Sci. 1980;26(21):1827-1831.
    • (1980) Life Sci. , vol.26 , Issue.21 , pp. 1827-1831
    • Zeisel, S.H.1    Epstein, M.F.2    Wurtman, R.J.3
  • 55
    • 0028868418 scopus 로고
    • Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver
    • Zeisel SH, Mar MH, Zhou Z, da Costa KA. Pregnancy and lactation are associated with diminished concentrations of choline and its metabolites in rat liver. J Nutr. 1995;125(12):3049-3054.
    • (1995) J Nutr. , vol.125 , Issue.12 , pp. 3049-3054
    • Zeisel, S.H.1    Mar, M.H.2    Zhou, Z.3    da Costa, K.A.4
  • 56
    • 77955496122 scopus 로고    scopus 로고
    • Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma
    • Fischer LM, da Costa KA, Galanko J, etal. Choline intake and genetic polymorphisms influence choline metabolite concentrations in human breast milk and plasma. Am J Clin Nutr. 2010;92(2):336-346.
    • (2010) Am J Clin Nutr. , vol.92 , Issue.2 , pp. 336-346
    • Fischer, L.M.1    da Costa, K.A.2    Galanko, J.3
  • 58
    • 0027525308 scopus 로고
    • Glycerophosphocholine and phosphocholine are the major choline metabolites in rat milk
    • Rohlfs EM, Garner SC, Mar MH, Zeisel SH. Glycerophosphocholine and phosphocholine are the major choline metabolites in rat milk. J Nutr. 1993;123(10):1762-1768.
    • (1993) J Nutr. , vol.123 , Issue.10 , pp. 1762-1768
    • Rohlfs, E.M.1    Garner, S.C.2    Mar, M.H.3    Zeisel, S.H.4
  • 59
    • 0023810729 scopus 로고
    • Uptake of choline by rat mammary-gland epithelial cells
    • Chao CK, Pomfret EA, Zeisel SH. Uptake of choline by rat mammary-gland epithelial cells. Biochem J. 1988;254(1):33-38.
    • (1988) Biochem J. , vol.254 , Issue.1 , pp. 33-38
    • Chao, C.K.1    Pomfret, E.A.2    Zeisel, S.H.3
  • 60
    • 0024267796 scopus 로고
    • Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine
    • Yang EK, Blusztajn JK, Pomfret EA, Zeisel SH. Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine. Biochem J. 1988;256(3):821-828.
    • (1988) Biochem J. , vol.256 , Issue.3 , pp. 821-828
    • Yang, E.K.1    Blusztajn, J.K.2    Pomfret, E.A.3    Zeisel, S.H.4
  • 61
    • 0022629488 scopus 로고
    • Choline, phosphatidylcholine and sphingomyelin in human and bovine milk and infant formulas
    • Zeisel SH, Char D, Sheard NF. Choline, phosphatidylcholine and sphingomyelin in human and bovine milk and infant formulas. J Nutr. 1986;116(1):50-58.
    • (1986) J Nutr. , vol.116 , Issue.1 , pp. 50-58
    • Zeisel, S.H.1    Char, D.2    Sheard, N.F.3
  • 62
    • 84860267035 scopus 로고    scopus 로고
    • Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans
    • Yan J, Jiang X, West AA, etal. Maternal choline intake modulates maternal and fetal biomarkers of choline metabolism in humans. Am J Clin Nutr. 2012;95(5):1060-1071.
    • (2012) Am J Clin Nutr. , vol.95 , Issue.5 , pp. 1060-1071
    • Yan, J.1    Jiang, X.2    West, A.A.3
  • 63
    • 79955371821 scopus 로고    scopus 로고
    • Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans
    • da Costa KA, Sanders LM, Fischer LM, Zeisel SH. Docosahexaenoic acid in plasma phosphatidylcholine may be a potential marker for in vivo phosphatidylethanolamine N-methyltransferase activity in humans. Am J Clin Nutr. 2011;93(5):968-974.
    • (2011) Am J Clin Nutr. , vol.93 , Issue.5 , pp. 968-974
    • da Costa, K.A.1    Sanders, L.M.2    Fischer, L.M.3    Zeisel, S.H.4
  • 64
    • 70349325995 scopus 로고    scopus 로고
    • Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function
    • Cao D, Kevala K, Kim J, etal. Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function. J Neurochem. 2009;111(2):510-521.
    • (2009) J Neurochem. , vol.111 , Issue.2 , pp. 510-521
    • Cao, D.1    Kevala, K.2    Kim, J.3
  • 65
    • 77955807773 scopus 로고    scopus 로고
    • Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline
    • Sha W, da Costa KA, Fischer LM, etal. Metabolomic profiling can predict which humans will develop liver dysfunction when deprived of dietary choline. FASEB J. 2010;24(8):2962-2975.
    • (2010) FASEB J. , vol.24 , Issue.8 , pp. 2962-2975
    • Sha, W.1    da Costa, K.A.2    Fischer, L.M.3
  • 66
  • 67
    • 27644581598 scopus 로고    scopus 로고
    • Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans
    • Kohlmeier M, da Costa KA, Fischer LM, Zeisel SH. Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans. Proc Natl Acad Sci U S A. 2005;102(44):16025-16030.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , Issue.44 , pp. 16025-16030
    • Kohlmeier, M.1    da Costa, K.A.2    Fischer, L.M.3    Zeisel, S.H.4
  • 68
    • 78651393082 scopus 로고    scopus 로고
    • Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction
    • Resseguie ME, da Costa KA, Galanko JA, Patel M, Davis IJ, Zeisel SH. Aberrant estrogen regulation of PEMT results in choline deficiency-associated liver dysfunction. J Biol Chem. 2011;286(2):1649-1658.
    • (2011) J Biol Chem. , vol.286 , Issue.2 , pp. 1649-1658
    • Resseguie, M.E.1    da Costa, K.A.2    Galanko, J.A.3    Patel, M.4    Davis, I.J.5    Zeisel, S.H.6
  • 69
    • 62149129730 scopus 로고    scopus 로고
    • Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted
    • Ivanov A, Nash-Barboza S, Hinkis S, Caudill MA. Genetic variants in phosphatidylethanolamine N-methyltransferase and methylenetetrahydrofolate dehydrogenase influence biomarkers of choline metabolism when folate intake is restricted. J Am Diet Assoc. 2009;109(2):313-318.
    • (2009) J Am Diet Assoc. , vol.109 , Issue.2 , pp. 313-318
    • Ivanov, A.1    Nash-Barboza, S.2    Hinkis, S.3    Caudill, M.A.4
  • 70
    • 0020623387 scopus 로고
    • Formation of methylamines from ingested choline and lecithin
    • Zeisel SH, Wishnok JS, Blusztajn JK. Formation of methylamines from ingested choline and lecithin. J Pharmacol Exp Ther. 1983; 225(2):320-324.
    • (1983) J Pharmacol Exp Ther. , vol.225 , Issue.2 , pp. 320-324
    • Zeisel, S.H.1    Wishnok, J.S.2    Blusztajn, J.K.3
  • 71
    • 0018376153 scopus 로고
    • Choline and lecithin in the treatment of tardive dyskinesia: Preliminary results from a pilot study
    • Gelenberg AJ, Doller-Wojcik JC, Growdon JH. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry. 1979;136(6):772-776.
    • (1979) Am J Psychiatry. , vol.136 , Issue.6 , pp. 772-776
    • Gelenberg, A.J.1    Doller-Wojcik, J.C.2    Growdon, J.H.3
  • 72
    • 79953733693 scopus 로고    scopus 로고
    • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    • Wang Z, Klipfell E, Bennett BJ, etal. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 2011; 472(7341):57-63.
    • (2011) Nature , vol.472 , Issue.7341 , pp. 57-63
    • Wang, Z.1    Klipfell, E.2    Bennett, B.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.