Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease

Epigenetics

Volumn 9, Issue 2, 2014, Pages 286-296

  Medici, Valentina ^a   Shibata, Noreene M ^a   Kharbanda, Kusum K ^b   Islam, Mohammad S ^c   Keen, Carl L ^a   Kim, Kyoungmi ^c   Tillman, Brittany ^d   French, Samuel W ^d   Halsted, Charles H ^a   LaSalle, Janine M ^c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA NEBRASKA WESTERN IOWA HEALTH CARE SYSTEM   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HARBOR UCLA MEDICAL CENTER   (United States)

Author keywords

Choline; Copper; CyclinD1; DNA methylation; Fetus; Liver; S adenosylmethionine

Indexed keywords

CARNITINE PALMITOYLTRANSFERASE I; CHOLINE; COMPLEMENTARY DNA; CYCLIN D1; DNA (CYTOSINE 5) METHYLTRANSFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; METHIONINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; WILSON DISEASE PROTEIN; COPPER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL GROWTH; CONTROLLED STUDY; DISEASE SEVERITY; DNA METHYLATION; FATTY LIVER; FEMALE; FETUS LIVER; FLUORESCENCE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOHISTOCHEMISTRY; LIPID METABOLISM; LIVER HISTOLOGY; MATERNAL NUTRITION; MOUSE; NONHUMAN; PERINATAL DEVELOPMENT; PUERPERIUM; PYROSEQUENCING; REAL TIME POLYMERASE CHAIN REACTION; WILSON DISEASE; ANIMAL; ANIMAL FOOD; C3H MOUSE; CYCLIND1; DIET; FETOMATERNAL TRANSFUSION; FETUS; LIVER; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PREGNANCY;

CHOLINE; COPPER; CYCLIND1; DNA METHYLATION; FETUS; LIVER; S-ADENOSYLMETHIONINE;

ANIMAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; ANIMALS; CHOLINE; COPPER; CYCLIN D1; DIET; DNA METHYLATION; FEMALE; FETUS; GENE EXPRESSION; HEPATOLENTICULAR DEGENERATION; LIPID METABOLISM; LIVER; MATERNAL-FETAL EXCHANGE; METHIONINE; MICE; MICE, INBRED C3H; PREGNANCY;

EID: 84892572547     PISSN: 15592294     EISSN: 15592308     Source Type: Journal    
DOI: 10.4161/epi.27110     Document Type: Article

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