TNFα-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase

Development

Volumn 136, Issue 5, 2009, Pages 865-875

  Matthews, Randolph P ^a   Lorent, Kristin ^a   Mañoral Mobias, Rafael ^a   Huang, Yuehua ^a   Gong, Weilong ^a   Murray, Ian V J ^a   Blair, Ian A ^a   Pack, Michael ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Lipid metabolism; Liver disease; Methionine metabolism; Methylation; TNF alpha; Zebrafish

Indexed keywords

3 DEAZAADENOSINE; ADENOSYLHOMOCYSTEINASE; DUCTTRIP PROTEIN; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZEBRAFISH PROTEIN; 3-DEAZAADENOSINE; METHIONINE; PRIMER DNA; TUBERCIDIN;

ANIMAL TISSUE; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DNA POLYMORPHISM; EMBRYO; ENZYME ACTIVITY; FATTY LIVER; GENE LOCUS; GENE MUTATION; LARVA; LIVER FATTY DEGENERATION; MALE; MISSENSE MUTATION; MITOCHONDRIAL DNA DISORDER; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RISK FACTOR; ZEBRA FISH; ANIMAL; BIOLOGICAL MODEL; COMPARATIVE STUDY; DISEASE MODEL; DRUG ANTAGONISM; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; LIPOGENESIS; LIVER DISEASE; LIVER MITOCHONDRION; METABOLISM; MUTATION; OXIDATIVE STRESS; SPECIES DIFFERENCE;

DANIO RERIO; HEPATITIS C VIRUS; MAMMALIA;

ADENOSYLHOMOCYSTEINASE; ANIMALS; BASE SEQUENCE; DISEASE MODELS, ANIMAL; DNA PRIMERS; FATTY LIVER; HUMANS; LARVA; LIPOGENESIS; LIVER DISEASES; MALE; METHIONINE; MITOCHONDRIA, LIVER; MODELS, BIOLOGICAL; MUTATION; OXIDATIVE STRESS; PHENOTYPE; SPECIES SPECIFICITY; TUBERCIDIN; TUMOR NECROSIS FACTOR-ALPHA; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 65549155682     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.027565     Document Type: Article

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