A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 18, 2014, Pages

  Barraud, Pierre ^a,c   Banerjee, Silpi ^b   Mohamed, Weaam I ^a   Jantsch, Michael F ^b   Allain, Frédéric H T ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF VIENNA   (Austria)

^c CNRS   (France)

Author keywords

NMR; Nucleocytoplasmic shuttling; RNA deamination; RNA binding protein

Indexed keywords

ADENOSINE DEAMINASE; DOUBLE STRANDED RNA; MOLECULAR SCAFFOLD; NUCLEAR PROTEIN; RNA BINDING PROTEIN; TRANSPORTIN 1; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; DNA FLANKING REGION; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; PROTEIN STRUCTURE;

NMR; NUCLEOCYTOPLASMIC SHUTTLING; RNA DEAMINATION; RNA-BINDING PROTEIN;

ACTIVE TRANSPORT, CELL NUCLEUS; ADENOSINE DEAMINASE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BETA KARYOPHERINS; HELA CELLS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR LOCALIZATION SIGNALS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; RNA, DOUBLE-STRANDED; SEQUENCE DELETION;

EID: 84899893118     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1323698111     Document Type: Article

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