Myeloid-derived suppressor cells enhance IgE-mediated mast cell responses

Journal of Leukocyte Biology

Volumn 95, Issue 4, 2014, Pages 643-650

  Morales, Johanna K ^a   Saleem, Sheinei J ^a   Martin, Rebecca K ^a   Saunders, Bryan L ^b   Barnstein, Brian O ^a   Faber, Travis W ^a   Pullen, Nicholas A ^a   Kolawole, Elizabeth Motunrayo ^a   Brooks, Keith B ^a   Norton, Sarah K ^a   Sturgill, Jamie ^a   Graham, Laura ^c   Bear, Harry D ^c   Urban Jr , Joseph F ^d   Lantz, Chris S ^b   Conrad, Daniel H ^a   Ryan, John J ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b JAMES MADISON UNIVERSITY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^d AGRICULTURAL RESEARCH SERVICE   (United States)

Author keywords

Allergy; Asthma; Inflammation; Nippostrongylus; Trichinella

Indexed keywords

IMMUNOGLOBULIN E;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL INTERACTION; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; IMMUNOREGULATION; INFECTION RESISTANCE; MAST CELL; MOUSE; MYELOID DERIVED SUPPRESSOR CELL; NEMATODIASIS; NIPPOSTRONGYLUS BRASILIENSIS; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; SUPPRESSOR CELL; TRICHINOSIS;

ALLERGY; ASTHMA; INFLAMMATION; NIPPOSTRONGYLUS; TRICHINELLA;

ANIMALS; ASTHMA; CELLS, CULTURED; CYTOKINES; FEMALE; IMMUNOGLOBULIN E; MAST CELLS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELOID CELLS; NIPPOSTRONGYLUS; TRICHINELLA SPIRALIS;

EID: 84899866279     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.0913510     Document Type: Article

References (36)

1. Galli, S. J., Tsai, M. (2012) IgE and mast cells in allergic disease. Nat. Med. 18, 693-704.
2. Kalesnikoff, J., Galli, S. J. (2010) Anaphylaxis: mechanisms of mast cell activation. Chem. Immunol. Allergy 95, 45-66.
3. Gilfillan, A. M., Rivera, J. (2009) The tyrosine kinase network regulating mast cell activation. Immunol. Rev. 228, 149-169.
4. Taylor, M. D., van der Werf, N., Maizels, R. M. (2012) T cells in helminth infection: the regulators and the regulated. Trends Immunol. 33, 181-189.
5. Cuervo, H., Guerrero, N. A., Carbajosa, S., Beschin, A., De Baetselier, P., Girones, N., Fresno, M. (2011) Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection. J. Immunol. 187, 2656-2665.
6. Van Ginderachter, J. A., Beschin, A., De Baetselier, P., Raes, G. (2010) Myeloid-derived suppressor cells in parasitic infections. Eur. J. Immunol. 40, 2976-2985.
7. Solito, S., Pinton, L., Damuzzo, V., Mandruzzato, S. (2012) Highlights on molecular mechanisms of MDSC-mediated immune suppression: paving the way for new working hypotheses. Immunol. Invest. 41, 722-737.
8. Lindau, D., Gielen, P., Kroesen, M., Wesseling, P., Adema, G. J. (2013) The immunosuppressive tumour network: myeloid-derived suppressor cells, regulatory T cells and natural killer T cells. Immunology 138, 105-115.
9. Raber, P., Ochoa, A. C., Rodriguez, P. C. (2012) Metabolism of L-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol. Invest. 41, 614-634.
10. Ostrand-Rosenberg, S. (2010) Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol. Immunother. 59, 1593-1600.
11. Waldron, T. J., Quatromoni, J. G., Karakasheva, T. A., Singhal, S., Rustgi, A. K. (2013) Myeloid derived suppressor cells: targets for therapy. Oncoimmunology 2, e24117.
12. Hensley, M. L. (2010) Update on gemcitabine and docetaxel combination therapy for primary and metastatic sarcomas. Curr. Opin. Oncol. 22, 356-361.
13. Sun, C., Ansari, D., Andersson, R., Wu, D. Q. (2012) Does gemcitabinebased combination therapy improve the prognosis of unresectable pancreatic cancer? World J. Gastroenterol. 18, 4944-4958.
14. Yang, Z., Zhang, B., Li, D., Lv, M., Huang, C., Shen, G. X., Huang, B. (2010) Mast cells mobilize myeloid-derived suppressor cells and Treg cells in tumor microenvironment via IL-17 pathway in murine hepatocarcinoma model. PLoS One 5, e8922.
15. Arora, M., Poe, S. L., Oriss, T. B., Krishnamoorthy, N., Yarlagadda, M., Wenzel, S. E., Billiar, T. R., Ray, A., Ray, P. (2010) TLR4/MyD88-induced CD11b+Gr-1 int F4/80+ non-migratory myeloid cells suppress Th2 effector function in the lung. Mucosal Immunol. 3, 578-593.
16. Arora, M., Poe, S. L., Ray, A., Ray, P. (2011) LPS-induced CD11b+Gr1(int)F4/80+ regulatory myeloid cells suppress allergen-induced airway inflammation. Int. Immunopharmacol. 11, 827-832.
17. Deshane, J., Zmijewski, J. W., Luther, R., Gaggar, A., Deshane, R., Lai, J. F., Xu, X., Spell, M., Estell, K., Weaver, C. T., Abraham, E., Schwiebert, L. M., Chaplin, D. D. (2011) Free radical-producing myeloid-derived regulatory cells: potent activators and suppressors of lung inflammation and airway hyperresponsiveness. Mucosal Immunol. 4, 503-518.
18. Saleem, S. J., Martin, R. K., Morales, J. K., Sturgill, J. L., Gibb, D. R., Graham, L., Bear, H. D., Manjili, M. H., Ryan, J. J., Conrad, D. H. (2012) Cutting edge: mast cells critically augment myeloid-derived suppressor cell activity. J. Immunol. 189, 511-515.
19. Gibb, D. R., Saleem, S. J., Kang, D. J., Subler, M. A., Conrad, D. H. (2011) ADAM10 overexpression shifts lympho-and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch. J. Immunol. 186, 4244-4252.
20. Ford, J. W., Sturgill, J. L., Conrad, D. H. (2009) 129/SvJ Mice have mutated CD23 and hyper IgE. Cell. Immunol. 254, 124-134.
21. Urban J. F., Jr., Schopf, L., Morris, S. C., Orekhova, T., Madden, K. B., Betts, C. J., Gamble, H. R., Byrd, C., Donaldson, D., Else, K., Finkelman, F. D. (2000) Stat6 signaling promotes protective immunity against Trichinella spiralis through a mast cell-and T cell-dependent mechanism. J. Immunol. 164, 2046-2052.
22. Abraham, S. N., St John, A. L. (2010) Mast cell-orchestrated immunity to pathogens. Nat. Rev. Immunol. 10, 440-452.
23. Ribatti, D. (2013) Mast cells and macrophages exert beneficial and detrimental effects on tumor progression and angiogenesis. Immunol. Lett. 152, 83-88.
24. Ostrand-Rosenberg, S., Sinha, P. (2009) Myeloid-derived suppressor cells: linking inflammation and cancer J. Immunol. 182, 4499-4506.
25. Youn, J. I., Nagaraj, S., Collazo, M., Gabrilovich, D. I. (2008) Subsets of myeloid-derived suppressor cells in tumor-bearing mice. J. Immunol. 181, 5791-5802.
26. Crowle, P. K., Reed, N. D. (1981) Rejection of the intestinal parasite Nippostrongylus brasiliensis by mast cell-deficient W/Wv anemic mice. Infect. Immun. 33, 54-58.
27. Le, H. K., Graham, L., Cha, E., Morales, J. K., Manjili, M. H., Bear, H. D. (2009) Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice. Int. Immunopharmacol. 9, 900-909.
28. Sinha, P., Clements, V. K., Bunt, S. K., Albelda, S. M., Ostrand-Rosenberg, S. (2007) Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J. Immunol. 179, 977-983.
29. Ha, T. Y., Reed, N. D., Crowle, P. K. (1983) Delayed expulsion of adult Trichinella spiralis by mast cell-deficient W/Wv mice. Infect. Immun. 41, 445-447.
30. Williams, C. M., Galli, S. J. (2000) Mast cells can amplify airway reactivity and features of chronic inflammation in an asthma model in mice. J. Exp. Med. 192, 455-462.
31. Urban J. F., Jr., Noben-Trauth, N., Donaldson, D. D., Madden, K. B., Morris, S. C., Collins, M., Finkelman, F. D. (1998) IL-13, IL-4Rα, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis. Immunity 8, 255-264.
32. Desai, D., Brightling, C. (2010) TNF-α antagonism in severe asthma? Recent Pat. Inflamm. Allergy Drug Discov. 4, 193-200.
33. Smart, S. J., Casale, T. B. (1994) TNF-α-induced transendothelial neutrophil migration is IL-8 dependent. Am. J. Physiol. 266, L238-L245.
34. Michel, A., Schuler, A., Friedrich, P., Doner, F., Bopp, T., Radsak, M., Hoffmann, M., Relle, M., Distler, U., Kuharev, J., Tenzer, S., Feyerabend, T. B., Rodewald, H. R., Schild, H., Schmitt, E., Becker, M., Stassen, M. (2013) Mast cell-deficient Kit(W-sh) "Sash" mutant mice display aberrant myelopoiesis leading to the accumulation of splenocytes that act as myeloid-derived suppressor cells. J. Immunol. 190, 5534-5544.
35. Pan, P. Y., Wang, G. X., Yin, B., Ozao, J., Ku, T., Divino, C. M., Chen, S. H. (2008) Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function. Blood 111, 219-228.
36. Kao, J., Ko, E. C., Eisenstein, S., Sikora, A. G., Fu, S., Chen, S. H. (2011) Targeting immune suppressing myeloid-derived suppressor cells in oncology. Crit. Rev. Oncol. Hematol. 77, 12-19.