-
1
-
-
0031985128
-
Granulocyte-macrophage colonystimulatingfactor-activated signaling pathways in human neutrophils. Selectiveactivation of Jak2, Stat3, and Stat5b
-
Al-Shami, A. , Mahanna, W. , and Naccache, P. H. (1998). Granulocyte-macrophage colonystimulatingfactor-activated signaling pathways in human neutrophils. Selectiveactivation of Jak2, Stat3, and Stat5b. J. Biol. Chem. 273: 1058-1063.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1058-1063
-
-
Al-Shami, A.1
Mahanna, W.2
Naccache, P.H.3
-
2
-
-
79951823584
-
Myeloid-derived suppressorcells in the peripheral blood of cancer patients contain a subset of immatureneutrophils with impaired migratory properties
-
Brandau, S. , Trellakis, S. , Bruderek, K. , Schmaltz, D. , Steller, G. , Elian, M. , Suttmann,H. , Schenck, M. , Welling, J. , Zabel, P. , and Lang, S. (2011). Myeloid-derived suppressorcells in the peripheral blood of cancer patients contain a subset of immatureneutrophils with impaired migratory properties. J. Leukoc. Biol. 89: 311-317.
-
(2011)
J. Leukoc. Biol.
, vol.89
, pp. 311-317
-
-
Brandau, S.1
Trellakis, S.2
Bruderek, K.3
Schmaltz, D.4
Steller, G.5
Elian, M.6
Suttmann, H.7
Schenck, M.8
Welling, J.9
Zabel, P.10
Lang, S.11
-
3
-
-
0033562982
-
Unopposed production of granulocyte-macrophage colony-stimulating factorby tumors inhibits CD8 + T cell responses by dysregulating antigen-presenting cellmaturation
-
Bronte, V. , Chappell, D. B. , Apolloni, E. , Cabrelle, A. , Wang, M. , Hwu, P. , Restifo, N. P. (1999). Unopposed production of granulocyte-macrophage colony-stimulating factorby tumors inhibits CD8 + T cell responses by dysregulating antigen-presenting cellmaturation. J. Immunol. 162: 5728-5737.
-
(1999)
J. Immunol.
, vol.162
, pp. 5728-5737
-
-
Bronte, V.1
Chappell, D.B.2
Apolloni, E.3
Cabrelle, A.4
Wang, M.5
Hwu, P.6
Restifo, N.P.7
-
4
-
-
33747606201
-
Leukocyte infiltration incancer creates an unfavorable environment for antitumor immune responses: Anovel target for therapeutic intervention
-
Bronte, V. , Cingarlini, S. , Marigo, I. , De Santo, C. , Gallina, G. , Dolcetti, L. , Ugel, S. ,Peranzoni, E. , Mandruzzato, S. , and Zanovello, P. (2006). Leukocyte infiltration incancer creates an unfavorable environment for antitumor immune responses: anovel target for therapeutic intervention. Immunol. Invest. 35: 327-357.
-
(2006)
Immunol. Invest.
, vol.35
, pp. 327-357
-
-
Bronte, V.1
Cingarlini, S.2
Marigo, I.3
De Santo, C.4
Gallina, G.5
Dolcetti, L.6
Ugel, S.7
Peranzoni, E.8
Mandruzzato, S.9
Zanovello, P.10
-
5
-
-
23444456772
-
Regulation of immune responses by L-argininemetabolism
-
Bronte, V. , and Zanovello, P. (2005). Regulation of immune responses by L-argininemetabolism. Nat. Rev. Immunol. 5: 641-654.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 641-654
-
-
Bronte, V.1
Zanovello, P.2
-
6
-
-
35448954376
-
Reduced inflammation in the tumor microenvironment delays the accumulationof myeloid-derived suppressor cells and limits tumor progression
-
Bunt, S. K. , Yang, L. , Sinha, P. , Clements, V. K. , Leips, J. , and Ostrand-Rosenberg, S. (2007). Reduced inflammation in the tumor microenvironment delays the accumulationof myeloid-derived suppressor cells and limits tumor progression. Cancer Res. 67: 10019-10026.
-
(2007)
Cancer Res.
, vol.67
, pp. 10019-10019
-
-
Bunt, S.K.1
Yang, L.2
Sinha, P.3
Clements, V.K.4
Leips, J.5
Ostrand-Rosenberg, S.6
-
7
-
-
53349099219
-
Inhibition of dendriticcell differentiation and accumulation of myeloid-derived suppressor cells in cancer isregulated by S100A9 protein
-
Cheng, P. , Corzo, C. A. , Luetteke, N. , Yu, B. , Nagaraj, S. , Bui, M. M. , Ortiz, M. , Nacken,W. , Sorg, C. , Vogl, T. , Roth, J. , and Gabrilovich, D. I. (2008). Inhibition of dendriticcell differentiation and accumulation of myeloid-derived suppressor cells in cancer isregulated by S100A9 protein. J. Exp. Med. 205: 2235-2249.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2235-2249
-
-
Cheng, P.1
Corzo, C.A.2
Luetteke, N.3
Yu, B.4
Nagaraj, S.5
Bui, M.M.6
Ortiz Nacken M, W.7
Sorg, C.8
Vogl, T.9
Roth, J.10
Gabrilovich, D.I.11
-
8
-
-
79952280133
-
Myeloid cell diversification and complexity: An old conceptwith new turns in oncology
-
Chioda, M. , Peranzoni, E. , Desantis, G. , Papalini, F. , Falisi, E. , Solito, S. , Mandruzzato,S. , and Bronte, V. (2011). Myeloid cell diversification and complexity: an old conceptwith new turns in oncology. Cancer Metastasis Rev. 30: 27-43.
-
(2011)
Cancer Metastasis Rev.
, vol.30
, pp. 27-43
-
-
Chioda, M.1
Peranzoni, E.2
Desantis, G.3
Papalini, F.4
Falisi, E.5
Solito, S.6
Mandruzzato, S.7
Bronte, V.8
-
9
-
-
83655163684
-
CD15( +)/CD16 (low) human granulocytes fromterminal cancer patients: Granulocyticmyeloidderivedsuppressor cells that have suppressive function
-
Choi, J. , Suh, B. , Ahn, Y. O. , Kim, T. M. , Lee, J. O. , Lee, S. H. , and Heo, D. S. (2012). CD15( +)/CD16 (low) human granulocytes fromterminal cancer patients: granulocyticmyeloidderivedsuppressor cells that have suppressive function. Tumour Biol. 33: 121-129.
-
(2012)
Tumour Biol.
, vol.33
, pp. 121-129
-
-
Choi, J.1
Suh, B.2
Ahn, Y.O.3
Kim, T.M.4
Lee, J.O.5
Lee, S.H.6
Heo, D.S.7
-
10
-
-
80051617751
-
GM-CSF production by glioblastomacells has a functional role in eosinophil survival, activation, and growth factorproduction for enhanced tumor cell proliferation
-
Curran, C. S. , Evans, M. D. , and Bertics, P. J. (2011). GM-CSF production by glioblastomacells has a functional role in eosinophil survival, activation, and growth factorproduction for enhanced tumor cell proliferation. J. Immunol. 187: 1254-1263.
-
(2011)
J. Immunol.
, vol.187
, pp. 1254-1263
-
-
Curran, C.S.1
Evans, M.D.2
Bertics, P.J.3
-
11
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlatewith clinical cancer stage, metastatic tumor burden, and doxorubicincyclophosphamidechemotherapy
-
Diaz-Montero, C. M. , Salem, M. L. , Nishimura, M. I. , Garrett-Mayer, E. , Cole, D. J. , andMontero, A. J. (2009). Increased circulating myeloid-derived suppressor cells correlatewith clinical cancer stage, metastatic tumor burden, and doxorubicincyclophosphamidechemotherapy. Cancer Immunol. Immunother. 58: 49-59.
-
(2009)
Cancer Immunol. Immunother.
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
Garrett-Mayer, E.4
Cole, D.J.5
Montero, A.J.6
-
12
-
-
74249101123
-
Hierarchyof immunosuppressive strength among myeloid-derived suppressor cell subsets isdetermined by GM-CSF
-
Dolcetti, L. , Peranzoni, E. , Ugel, S. , Marigo, I. , Fernandez Gomez, A. , Mesa, C. , Geilich,M. , Winkels, G. , Traggiai, E. , Casati, A. , Grassi, F. , and Bronte, V. (2010). Hierarchyof immunosuppressive strength among myeloid-derived suppressor cell subsets isdetermined by GM-CSF. Eur. J. Immunol. 40: 22-35.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 22-35
-
-
Dolcetti, L.1
Peranzoni, E.2
Ugel, S.3
Marigo, I.4
Fernandez Gomez, A.5
Mesa, C.6
Geilich, M.7
Winkels, G.8
Traggiai, E.9
Casati, A.10
Grassi, F.11
Bronte, V.12
-
13
-
-
33749134855
-
TCR zeta down-regulationunder chronic inflammation is mediated by myeloid suppressor cells differentiallydistributed between various lymphatic organs
-
Ezernitchi, A. V. , Vaknin, I. , Cohen-Daniel, L. , Levy, O. , Manaster, E. , Halabi, A. ,Pikarsky, E, Shapira, L. , and Baniyash, M. (2006). TCR zeta down-regulationunder chronic inflammation is mediated by myeloid suppressor cells differentiallydistributed between various lymphatic organs. J. Immunol. 177: 4763-4772.
-
(2006)
J. Immunol.
, vol.177
, pp. 4763-4772
-
-
Ezernitchi, A.V.1
Vaknin, I.2
Cohen-Daniel, L.3
Levy, O.4
Manaster, E.5
Halabi, A.6
Pikarsky, E.7
Shapira, L.8
Baniyash, M.9
-
14
-
-
84856706929
-
Phenotype, function and clinical implicationsof myeloid-derived suppressor cells in cancer patients
-
Filipazzi, P. , Huber, V. , and Rivoltini, L. (2012). Phenotype, function and clinical implicationsof myeloid-derived suppressor cells in cancer patients. Cancer Immunol. Immunother. 61: 255-263.
-
(2012)
Cancer Immunol. Immunother.
, vol.61
, pp. 255-263
-
-
Filipazzi, P.1
Huber, V.2
Rivoltini, L.3
-
15
-
-
34447258415
-
Identification of a new subset of myeloidsuppressor cells in peripheral blood of melanoma patients with modulation by agranulocyte-macrophage colony-stimulation factor-based antitumor vaccine
-
Filipazzi, P. , Valenti, R. , Huber, V. , Pilla, L. , Canese, P. , Iero, M. , Castelli, C. , Mariani, L. ,Parmiani, G. , and Rivoltini, L. (2007). Identification of a new subset of myeloidsuppressor cells in peripheral blood of melanoma patients with modulation by agranulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J. Clin. Oncol. 25: 2546-2553.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 2546-2553
-
-
Filipazzi, P.1
Valenti, R.2
Huber, V.3
Pilla, L.4
Canese, P.5
Iero, M.6
Castelli, C.7
Mariani, L.8
Parmiani, G.9
Rivoltini, L.10
-
16
-
-
79958052123
-
MDSC as amechanism of tumor escape from sunitinib mediated anti-angiogenic therapy
-
Finke, J. , Ko, J. , Rini, B. , Rayman, P. , Ireland, J. , and Cohen, P. (2011). MDSC as amechanism of tumor escape from sunitinib mediated anti-angiogenic therapy. Int. Immunopharmacol. 11: 856-861.
-
(2011)
Int. Immunopharmacol.
, vol.11
, pp. 856-861
-
-
Finke, J.1
Ko, J.2
Rini, B.3
Rayman, P.4
Ireland, J.5
Cohen, P.6
-
17
-
-
0032400862
-
Vascular endothelial growth factor inhibits the development of dendritic cellsand dramatically affects the differentiation of multiple hematopoietic lineagesin vivo
-
Gabrilovich, D. , Ishida, T. , Oyama, T. , Ran, S. , Kravtsov, V. , Nadaf, S. , and Carbone, D. P. (1998). Vascular endothelial growth factor inhibits the development of dendritic cellsand dramatically affects the differentiation of multiple hematopoietic lineagesin vivo. Blood 92: 4150-4166.
-
(1998)
Blood
, vol.92
, pp. 4150-4166
-
-
Gabrilovich, D.1
Ishida, T.2
Oyama, T.3
Ran, S.4
Kravtsov, V.5
Nadaf, S.6
Carbone, D.P.7
-
18
-
-
33846434093
-
The terminology issue for myeloid-derived suppressorcells
-
author reply 426
-
Gabrilovich, D. I. , Bronte, V. , Chen, S. H. , Colombo, M. P. , Ochoa, A. , Ostrand-Rosenberg,S. , and Schreiber, H. (2007). The terminology issue for myeloid-derived suppressorcells. Cancer Res 67: 425; author reply 426.
-
(2007)
Cancer Res
, vol.67
, pp. 425
-
-
Gabrilovich, D.I.1
Bronte, V.2
Chen, S.H.3
Colombo, M.P.4
Ochoa, A.5
Ostrand-Rosenberg, S.6
Schreiber, H.7
-
19
-
-
61349100687
-
Myeloid-derived suppressor cells as regulatorsof the immune system
-
Gabrilovich, D. I. , and Nagaraj, S. (2009). Myeloid-derived suppressor cells as regulatorsof the immune system. Nat. Rev. Immunol. 9: 162-174.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
20
-
-
33749425534
-
Tumorsinduce a subset of inflammatory monocytes with immunosuppressive activity onCD8 + T cells
-
Gallina, G. , Dolcetti, L. , Serafini, P. , De Santo, C. , Marigo, I. , Colombo, M. P. , Basso, G. ,Brombacher, F. , Borrello, I. , Zanovello, P. , Bicciato, S. , and Bronte, V. (2006). Tumorsinduce a subset of inflammatory monocytes with immunosuppressive activity onCD8 + T cells. J. Clin. Invest. 116: 2777-2790.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
De Santo, C.4
Marigo, I.5
Colombo, M.P.6
Basso, G.7
Brombacher, F.8
Borrello, I.9
Zanovello, P.10
Bicciato, S.11
Bronte, V.12
-
21
-
-
70249140303
-
Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4 + andCD8 + T cells
-
Hanson, E. M. , Clements, V. K. , Sinha, P. , Ilkovitch, D. , and Ostrand-Rosenberg, S. (2009). Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4 + andCD8 + T cells. J. Immunol. 183: 937-944.
-
(2009)
J. Immunol.
, vol.183
, pp. 937-944
-
-
Hanson, E.M.1
Clements, V.K.2
Sinha, P.3
Ilkovitch, D.4
Ostrand-Rosenberg, S.5
-
22
-
-
42649129014
-
Systematic review of the associationbetween circulating interleukin-6 (IL-6) and cancer
-
Heikkila, K. , Ebrahim, S. , and Lawlor, D. A. (2008). Systematic review of the associationbetween circulating interleukin-6 (IL-6) and cancer. Eur. J. Cancer 44: 937-945.
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 937-945
-
-
Heikkila, K.1
Ebrahim, S.2
Lawlor, D.A.3
-
23
-
-
31544446571
-
Gr-1 +CD115 + immature myeloid suppressor cells mediate the developmentof tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
-
Huang, B. , Pan, P. Y. , Li, Q. , Sato, A. I. , Levy, D. E, Bromberg, J. , Divino, C. M. , and Chen,S. H. (2006). Gr-1 +CD115 + immature myeloid suppressor cells mediate the developmentof tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 66: 1123-1131.
-
(2006)
Cancer Res.
, vol.66
, pp. 1123-1131
-
-
Huang, B.1
Pan, P.Y.2
Li, Q.3
Sato, A.I.4
Levy, D.E.5
Bromberg, J.6
Divino, C.M.7
Chens, H.8
-
24
-
-
67650422616
-
The liver is a site for tumor-induced myeloidderivedsuppressor cell accumulation and immunosuppression
-
Ilkovitch, D. , and Lopez, D. M. (2009). The liver is a site for tumor-induced myeloidderivedsuppressor cell accumulation and immunosuppression. Cancer Res. 69: 5514-5521.
-
(2009)
Cancer Res.
, vol.69
, pp. 5514-5514
-
-
Ilkovitch, D.1
Lopez, D.M.2
-
25
-
-
51549091457
-
Tumor-educatedtolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of Tcells through oxygen-dependent pathways
-
Kuang, D. M. , Zhao, Q. , Xu, J. , Yun, J. P. , Wu, C. , and Zheng, L. (2008). Tumor-educatedtolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of Tcells through oxygen-dependent pathways. J. Immunol. 181: 3089-3098.
-
(2008)
J. Immunol.
, vol.181
, pp. 3089-3098
-
-
Kuang, D.M.1
Zhao, Q.2
Xu, J.3
Yun, J.P.4
Wu, C.5
Zheng, L.6
-
26
-
-
58149332680
-
Reversal of myeloid cell-mediated immunosuppressionin patients with metastatic renal cell carcinoma
-
Kusmartsev, S. , Su, Z. , Heiser, A. , Dannull, J. , Eruslanov, E. , Kubler, H. , Yancey, D. ,Dahm, P. , and Vieweg, J. (2008). Reversal of myeloid cell-mediated immunosuppressionin patients with metastatic renal cell carcinoma. Clin. Cancer Res. 14: 8270-8278.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 8270-8278
-
-
Kusmartsev, S.1
Su, Z.2
Heiser, A.3
Dannull, J.4
Eruslanov, E.5
Kubler, H.6
Yancey, D.7
Dahm, P.8
Vieweg, J.9
-
27
-
-
77956920766
-
Characterization of cytokineinducedmyeloid-derived suppressor cells from normal human peripheral bloodmononuclear cells
-
Lechner, M. G. , Liebertz, D. J. , and Epstein, A. L. (2010). Characterization of cytokineinducedmyeloid-derived suppressor cells from normal human peripheral bloodmononuclear cells. J. Immunol. 185: 2273-2284.
-
(2010)
J. Immunol.
, vol.185
, pp. 2273-2284
-
-
Lechner, M.G.1
Liebertz, D.J.2
Epstein, A.L.3
-
28
-
-
79958066494
-
Functional characterization of human Cd33 + and Cd11b + myeloidderivedsuppressor cell subsets induced from peripheral blood mononuclear cellsco-cultured with a diverse set of human tumor cell lines
-
Lechner, M. G. , Megiel, C. , Russell, S. M. , Bingham, B. , Arger, N. , Woo, T. , and Epstein,A. L. (2011). Functional characterization of human Cd33 + and Cd11b + myeloidderivedsuppressor cell subsets induced from peripheral blood mononuclear cellsco-cultured with a diverse set of human tumor cell lines. J. Transl. Med. 9: 90.
-
(2011)
J. Transl. Med.
, vol.9
, pp. 90
-
-
Lechner, M.G.1
Megiel, C.2
Russell, S.M.3
Bingham, B.4
Arger, N.5
Woo, T.6
Epstein, A.L.7
-
29
-
-
59849126377
-
Cancer-expanded myeloid-derivedsuppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1
-
Li, H. , Han, Y. , Guo, Q. , Zhang, M. , and Cao, X. (2009). Cancer-expanded myeloid-derivedsuppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1. J. Immunol. 182: 240-249.
-
(2009)
J Immunol.
, vol.182
, pp. 240-249
-
-
Li, H.1
Han, Y.2
Guo, Q.3
Zhang, M.4
Cao, X.5
-
30
-
-
70350133511
-
IL4Ralpha + myeloid-derived suppressor cell expansion in cancer patients
-
Mandruzzato, S. , Solito, S. , Falisi, E. , Francescato, S. , Chiarion-Sileni, V. , Mocellin, S. ,Zanon, A. , Rossi, C. R. , Nitti, D. , Bronte, V. , and Zanovello, P. (2009). IL4Ralpha + myeloid-derived suppressor cell expansion in cancer patients. J. Immunol. 182: 6562-6568.
-
(2009)
J. Immunol.
, vol.182
, pp. 6562-6562
-
-
Mandruzzato, S.1
Solito, S.2
Falisi, E.3
Francescato, S.4
Chiarion-Sileni, V.5
Mocellin, S.6
Zanon, A.7
Rossi, C.R.8
Nitti, D.9
Bronte, V.10
Zanovello, P.11
-
31
-
-
77953914366
-
Tumor-induced tolerance and immune suppressiondepend on the C/EBPbeta transcription factor
-
Marigo, I. , Bosio, E. , Solito, S. , Mesa, C. , Fernandez, A. , Dolcetti, L. , Ugel, S. , Sonda, N. ,Bicciato, S. , Falisi, E. , Calabrese, F. , Basso, G. , Zanovello, P. , Cozzi, E. ,Mandruzzato, S. and Bronte, V. (2010). Tumor-induced tolerance and immune suppressiondepend on the C/EBPbeta transcription factor. Immunity 32: 790-802.
-
(2010)
Immunity
, vol.32
, pp. 790-802
-
-
Marigo, I.1
Bosio, E.2
Solito, S.3
Mesa, C.4
Fernandez, A.5
Dolcetti, L.6
Ugel, S.7
Sonda, N.8
Bicciato, S.9
Falisi, E.10
Calabrese, F.11
Basso, G.12
Zanovello, P.13
Cozzi, E.14
Mandruzzato, S.15
Bronte, V.16
-
32
-
-
54549109936
-
Modulation of the antitumorimmune response by complement
-
Markiewski, M. M. , DeAngelis, R. A. , Benencia, F. , Ricklin-Lichtsteiner, S. K. , Koutoulaki,A. , Gerard, C. , Coukos, G. , and Lambris, J. D. (2008/0. Modulation of the antitumorimmune response by complement. Nat Immunol 9: 1225-1235.
-
(2008)
Nat Immunol
, vol.9
, pp. 1225-1225
-
-
Markiewski, M.M.1
Deangelis, R.A.2
Benencia, F.3
Ricklin-Lichtsteiner, S.K.4
Koutoulaki, A.5
Gerard, C.6
Coukos, G.7
Lambris, J.D.8
-
33
-
-
70349247889
-
Activated CD11b +CD15 +granulocytes increase in the blood of patientswith uveal melanoma
-
McKenna, K. C. , Beatty, K. M. , Bilonick, R. A. , Schoenfield, L. , Lathrop, K. L. , and Singh,A. D. (2009). Activated CD11b +CD15 +granulocytes increase in the blood of patientswith uveal melanoma. Invest. Ophthalmol. Vis. Sci. 50: 4295-4303.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 4295-4303
-
-
McKenna, K.C.1
Beatty, K.M.2
Bilonick, R.A.3
Schoenfield, L.4
Lathrop, K.L.5
Singh, A.D.6
-
34
-
-
80054730389
-
Chronic inflammationpromotes myeloid-derived suppressor cell activation blocking antitumor immunityin transgenic mouse melanoma model
-
Meyer, C. , Sevko, A. , Ramacher, M. , Bazhin, A. V. , Falk, C. S. ; Osen, W. , Borrello, I. , Kato,M. , Schadendorf, D. , Baniyash, M. , and Umansky, V. (2011). Chronic inflammationpromotes myeloid-derived suppressor cell activation blocking antitumor immunityin transgenic mouse melanoma model. Proc Natl Acad Sci USA 108: 17111-17116.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 17111-17116
-
-
Meyer, C.1
Sevko, A.2
Ramacher, M.3
Bazhin, A.V.4
Falk, C.S.5
Osen, W.6
Borrello, I.7
Kato, M.8
Schadendorf, D.9
Baniyash, M.10
Umansky, V.11
-
35
-
-
84555205600
-
IL-6/IL-6receptor system and its role in physiological and pathological conditions
-
Mihara, M. , Hashizume, M. , Yoshida, H. , Suzuki, M. , and Shiina, M. (2012). IL-6/IL-6receptor system and its role in physiological and pathological conditions. Clin. Sci. (Lond. ) 122: 143-159.
-
(2012)
Clin. Sci. (Lond. )
, vol.122
, pp. 143-159
-
-
Mihara, M.1
Hashizume, M.2
Yoshida, H.3
Suzuki, M.4
Shiina, M.5
-
36
-
-
80054694464
-
Chemokine nitrationprevents intratumoral infiltration of antigen-specific T cells
-
Molon, B. , Ugel, S. , Del Pozzo, F. , Soldani, C. , Zilio, S. , Avella, D. , De Palma, A. , Mauri, P. ,Monegal, A. , Rescigno,M. , Savino, B. , Colombo, P. , Jonjic,N. , Pecanic, S. , Lazzarato, L. ,Fruttero, R. , Gasco, A. , Bronte, V. , and Viola, A. (2011). Chemokine nitrationprevents intratumoral infiltration of antigen-specific T cells. J. Exp. Med. 208: 1949-1962.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 1949-1962
-
-
Molon, B.1
Ugel, S.2
Del Pozzo, F.3
Soldani, C.4
Zilio, S.5
Avella, D.6
De Palma, A.7
Mauri, P.8
Monegal, A.9
Rescigno, M.10
Savino, B.11
Colombo, P.12
Jonjic, N.13
Pecanic, S.14
Lazzarato, L.15
Fruttero, R.16
Gasco, A.17
Bronte, V.18
Viola, A.19
-
37
-
-
84856899903
-
Myeloid-derived suppressor cells in cancer patients: A clinical perspective
-
Montero, A. J. , Diaz-Montero, C. M. , Kyriakopoulos, C. E. , Bronte, V. , and Mandruzzato, S. (2012). Myeloid-derived suppressor cells in cancer patients: A clinical perspective. J. Immunother. 35: 107-115.
-
(2012)
J. Immunother.
, vol.35
, pp. 107-115
-
-
Montero, A.J.1
Diaz-Montero, C.M.2
Kyriakopoulos, C.E.3
Bronte, V.4
Mandruzzato, S.5
-
38
-
-
0027773087
-
GM-CSF production in human adenocarcinomacell lines
-
Monti, F. , Szymczuk, S. , Motta, M. R. , Benini, C. , Fattori, P. P. , Pini, E. , Pasquini, E. , Zoli,W. , Amadori, D. , and Ravaioli, A. (1993). GM-CSF production in human adenocarcinomacell lines. J. Biol. Regul. Homeost. Agents 7: 85-91.
-
(1993)
J. Biol. Regul. Homeost. Agents
, vol.7
, pp. 85-91
-
-
Monti, F.1
Szymczuk, S.2
Motta, M.R.3
Benini, C.4
Fattori, P.P.5
Pini, E.6
Pasquini, E.7
Zoli, W.8
Amadori, D.9
Ravaioli, A.10
-
39
-
-
77955771348
-
GM-CSF is one of the main breast tumor-derived soluble factors involved in thedifferentiation of CD11b-Gr1-bone marrow progenitor cells into myeloid-derivedsuppressor cells
-
Morales, J. K. , Kmieciak, M. , Knutson, K. L. , Bear, H. D. , and Manjili. M. H. (2010). GM-CSF is one of the main breast tumor-derived soluble factors involved in thedifferentiation of CD11b-Gr1-bone marrow progenitor cells into myeloid-derivedsuppressor cells. Breast Cancer Res. Treat. 123: 39-49.
-
(2010)
Breast Cancer Res. Treat.
, vol.123
, pp. 39-49
-
-
Morales, J.K.1
Kmieciak, M.2
Knutson, K.L.3
Bear, H.D.4
Manjili, M.H.5
-
40
-
-
34447118098
-
Altered recognition of antigen is a mechanism ofCD8 + T cell tolerance in cancer
-
Nagaraj, S. , Gupta, K. ,Pisarev, V. , Kinarsky, L. , Sherman, S. , Kang, L. , Herber, D. L. ,Schneck, J. , Gabrilovich, D. I. (2007). Altered recognition of antigen is a mechanism ofCD8 + T cell tolerance in cancer. Nat. Med. 13: 828-835.
-
(2007)
Nat. Med.
, vol.13
, pp. 828-835
-
-
Nagaraj, S.1
Gupta, K.2
Pisarev, V.3
Kinarsky, L.4
Sherman, S.5
Kang, L.6
Herber, D.L.7
Schneck, J.8
Gabrilovich, D.I.9
-
41
-
-
84857205712
-
Antigen-specific CD4 + T cells regulate function of myeloid-derived suppressor cellsin cancer via retrograde MHC class II signaling
-
Nagaraj, S. , Nelson, A. , Youn, J. I. , Cheng, P. , Quiceno, D. , and Gabrilovich, D. I. (2012). Antigen-specific CD4 + T cells regulate function of myeloid-derived suppressor cellsin cancer via retrograde MHC class II signaling. Cancer Ress
-
(2012)
Cancer Ress
-
-
Nagaraj, S.1
Nelson, A.2
Youn, J.I.3
Cheng, P.4
Quiceno, D.5
Gabrilovich, D.I.6
-
42
-
-
84255170450
-
PGE2-Induced CXCL12 Production and CXCR4 expression controls the accumulationof human MDSCs in ovarian cancer environment
-
Obermajer, N. , Muthuswamy, R. , Odunsi, K. , Edwards, R. P. , and Kalinski, P. (2011). PGE2-Induced CXCL12 Production and CXCR4 expression controls the accumulationof human MDSCs in ovarian cancer environment. Cancer Res. 71: 7463-7470.
-
(2011)
Cancer Res.
, vol.71
, pp. 7463-7470
-
-
Obermajer, N.1
Muthuswamy, R.2
Odunsi, K.3
Edwards, R.P.4
Kalinski, P.5
-
43
-
-
0029841427
-
Oxidative stress bytumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cellreceptor complex and antigen-specific T-cell responses
-
Otsuji, M. , Kimura, Y. , Aoe, T. , Okamoto, Y. , and Saito, T. (1996). Oxidative stress bytumor-derived macrophages suppresses the expression of CD3 zeta chain of T-cellreceptor complex and antigen-specific T-cell responses. Proc. Natl. Acad. Sci. USA93: 13119-13124.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13119-13119
-
-
Otsuji, M.1
Kimura, Y.2
Aoe, T.3
Okamoto, Y.4
Saito, T.5
-
44
-
-
33847258205
-
Opposite immune functions of GM-CSF administered as vaccine adjuvantin cancer patients
-
Parmiani, G. , Castelli, C. , Pilla, L. , Santinami, M. , Colombo, M. P. , and Rivoltini, L. (2007). Opposite immune functions of GM-CSF administered as vaccine adjuvantin cancer patients. Ann. Oncol. 18: 226-232.
-
(2007)
Ann. Oncol.
, vol.18
, pp. 226-232
-
-
Parmiani, G.1
Castelli, C.2
Pilla, L.3
Santinami, M.4
Colombo, M.P.5
Rivoltini, L.6
-
45
-
-
77951258918
-
Myeloid-derived suppressor cell heterogeneity and subset definition
-
Peranzoni, E. , Zilio, S. , Marigo, I. , Dolcetti, L. , Zanovello, P. , Mandruzzato, S. , andBronte, V. (2010). Myeloid-derived suppressor cell heterogeneity and subset definition. Curr. Opin. Immunol. 22: 238-244.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 238-244
-
-
Peranzoni, E.1
Zilio, S.2
Marigo, I.3
Dolcetti, L.4
Zanovello, P.5
Mandruzzato, S.6
Bronte, V.7
-
46
-
-
77953141534
-
Immature immunosuppressive CD14 +HLA-DR-/low cells in melanoma patientsare Stat3hi and overexpress CD80 CD83, and DC-sign
-
Poschke, I. , D. Mougiakakos, J. Hansson, G. V. Masucci, and R. Kiessling. 2010. Immature immunosuppressive CD14 +HLA-DR-/low cells in melanoma patientsare Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res 70: 4335-4345.
-
(2010)
Cancer Res
, vol.70
, pp. 4335-4345
-
-
Poschke, I.1
Mougiakakos, D.2
Hansson, J.3
Masucci, G.V.4
Kiessling, R.5
-
47
-
-
60549088732
-
Arginase I-producing myeloid-derived suppressor cells in renal cellcarcinoma are a subpopulation of activated granulocytes
-
Rodriguez, P. C. , Ernstoff, M. S. , Hernandez, C. , Atkins, M. , Zabaleta, J. , Sierra, R. , andOchoa, A. C. 2009. Arginase I-producing myeloid-derived suppressor cells in renal cellcarcinoma are a subpopulation of activated granulocytes. Cancer Res. 69: 1553-1560.
-
(2009)
Cancer Res.
, vol.69
, pp. 1553-1560
-
-
Rodriguez, P.C.1
Ernstoff, M.S.2
Hernandez, C.3
Atkins, M.4
Zabaleta, J.5
Sierra, R.6
Ochoa, A.C.7
-
48
-
-
41149148269
-
Arginine regulation by myeloid derived suppressorcells and tolerance in cancer: Mechanisms and therapeutic perspectives
-
Rodriguez, P. C. , and Ochoa, A. C. (2008). Arginine regulation by myeloid derived suppressorcells and tolerance in cancer: mechanisms and therapeutic perspectives. Immunol. Rev. 222: 180-191.
-
(2008)
Immunol Rev.
, vol.222
, pp. 180-191
-
-
Rodriguez, P.C.1
Ochoa, A.C.2
-
49
-
-
0029973703
-
Human prostate carcinoma cell lines secrete GM-CSF and express GM-CSF-receptoron their cell surface
-
Rokhlin, O. W. , Griebling, T. L. , Karassina, N. V. , Raines, M. A. , and Cohen, M. B. (1996). Human prostate carcinoma cell lines secrete GM-CSF and express GM-CSF-receptoron their cell surface. Anticancer Res. 16: 557-563.
-
(1996)
Anticancer Res.
, vol.16
, pp. 557-563
-
-
Rokhlin, O.W.1
Griebling, T.L.2
Karassina, N.V.3
Raines, M.A.4
Cohen, M.B.5
-
50
-
-
0035987985
-
Down-regulation of the CD3-zeta chain in sentinel node biopsies from breast cancerpatients
-
Schule, J. , Bergkvist, L. , Hakansson, L. , Gustafsson, B. , and Hakansson, A. (2002). Down-regulation of the CD3-zeta chain in sentinel node biopsies from breast cancerpatients. Breast Cancer Res. Treat. 74: 33-40.
-
(2002)
Breast Cancer Res. Treat.
, vol.74
, pp. 33-40
-
-
Schule, J.1
Bergkvist, L.2
Hakansson, L.3
Gustafsson, B.4
Hakansson, A.5
-
51
-
-
33751531874
-
Phosphodiesterase-5 inhibition augments endogenousantitumor immunity by reducing myeloid-derived suppressor cell function
-
Serafini, P. , Meckel, K. , Kelso, M. , Noonan, K. , Califano, J. , Koch, W. , Dolcetti, L. , Bronte,V. , and Borrello, I. (2006). Phosphodiesterase-5 inhibition augments endogenousantitumor immunity by reducing myeloid-derived suppressor cell function. J. Exp. Med. 203: 2691-2702.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 2691-2702
-
-
Serafini, P.1
Meckel, K.2
Kelso, M.3
Noonan, K.4
Califano, J.5
Koch, W.6
Dolcetti, L.7
Bronte, V.8
Borrello, I.9
-
52
-
-
48549085973
-
Myeloid-derived suppressorcells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
-
Serafini, P. , Mgebroff, S. , Noonan, K. , and Borrello, I. (2008). Myeloid-derived suppressorcells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 68: 5439-5449.
-
(2008)
Cancer Res.
, vol.68
, pp. 5439-5449
-
-
Serafini, P.1
Mgebroff, S.2
Noonan, K.3
Borrello, I.4
-
53
-
-
79956348160
-
Myeloid-derived suppressor cells express the death receptorFas and apoptose in response to T cell-expressed FasL
-
Sinha, P. , Chornoguz, O. , Clements, V. K. , Artemenko, K. A. , Zubarev, R. A. , and Ostrand-Rosenberg, S. (2011). Myeloid-derived suppressor cells express the death receptorFas and apoptose in response to T cell-expressed FasL. Blood 117: 5381-5390.
-
(2011)
Blood
, vol.117
, pp. 5381-5390
-
-
Sinha, P.1
Chornoguz, O.2
Clements, V.K.3
Artemenko, K.A.4
Zubarev, R.A.5
Ostrand-Rosenberg, S.6
-
54
-
-
34249300128
-
Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressorcells
-
Sinha, P. , Clements, V. K. , Fulton, A. M. , and Ostrand-Rosenberg, S. (2007). Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressorcells. Cancer Res. 67: 4507-4513.
-
(2007)
Cancer Res.
, vol.67
, pp. 4507-4513
-
-
Sinha, P.1
Clements, V.K.2
Fulton, A.M.3
Ostrand-Rosenberg, S.4
-
55
-
-
79959856425
-
Antigen specificity of immune suppressionby myeloid-derived suppressor cells
-
Solito, S. , Bronte, V. , and Mandruzzato, S. (2011a). Antigen specificity of immune suppressionby myeloid-derived suppressor cells. J. Leukoc. Biol. 90: 31-36.
-
(2011)
J. Leukoc. Biol.
, vol.90
, pp. 31-36
-
-
Solito, S.1
Bronte, V.2
Mandruzzato, S.3
-
56
-
-
80052178466
-
A human promyelocytic-like population is responsiblefor the immune suppression mediated by myeloid-derived suppressor cells
-
Solito, S. , Falisi, E. , Diaz-Montero, C. M. , Doni, A. , Pinton, L. , Rosato, A. , Francescato, S. ,Basso, G. , Zanovello, P. , Onicescu, G. , Garrett-Mayer, E. , Montero, A. J. , Bronte, V. ,and Mandruzzato, S. (2011b). A human promyelocytic-like population is responsiblefor the immune suppression mediated by myeloid-derived suppressor cells. Blood118: 2254-2265.
-
(2011)
Blood
, vol.118
, pp. 2254-2254
-
-
Solito, S.1
Falisi, E.2
Diaz-Montero, C.M.3
Doni, A.4
Pinton, L.5
Rosato, A.6
Francescato, S.7
Basso, G.8
Zanovello, P.9
Onicescu, G.10
Garrett-Mayer, E.11
Montero, A.J.12
Bronte, V.13
Mandruzzato, S.14
-
57
-
-
79953113052
-
Transcription factorsin myeloid-derived suppressor cell recruitment and function
-
Sonda, N. , Chioda, M. , Zilio, S. , Simonato, F. , and Bronte, V. (2011). Transcription factorsin myeloid-derived suppressor cell recruitment and function. Curr. Opin. Immunol. 23: 279-285.
-
(2011)
Curr. Opin. Immunol.
, vol.23
, pp. 279-279
-
-
Sonda, N.1
Chioda, M.2
Zilio, S.3
Simonato, F.4
Bronte, V.5
-
58
-
-
29144504335
-
CD11b +Gr-1 + immature myeloid cells mediate suppression of Tcells in mice bearing tumors of IL-1beta-secreting cells
-
Song, X. , Krelin, Y. , Dvorkin, T. , Bjorkdahl, O. , Segal, S. , Dinarello, C. A. , Voronov, E. , andApte, R. N. (2005). CD11b +Gr-1 + immature myeloid cells mediate suppression of Tcells in mice bearing tumors of IL-1beta-secreting cells. J. Immunol. 175: 8200-8208.
-
(2005)
J. Immunol.
, vol.175
, pp. 8200-8208
-
-
Song, X.1
Krelin, Y.2
Dvorkin, T.3
Bjorkdahl, O.4
Segal, S.5
Dinarello, C.A.6
Voronov, E.7
Apte, R.N.8
-
59
-
-
48149107380
-
Lung cancer patients' CD4( +) T cells are activatedin vitro by MHC II cell-based vaccines despite the presence of myeloid-derivedsuppressor cells
-
Srivastava, M. K. , Bosch, J. J. , Thompson, J. A. , Ksander, B. R. , Edelman, M. J. , andOstrand-Rosenberg, S. (2008). Lung cancer patients' CD4( +) T cells are activatedin vitro by MHC II cell-based vaccines despite the presence of myeloid-derivedsuppressor cells. Cancer Immunol. Immunother. 57: 1493-1504.
-
(2008)
Cancer Immunol. Immunother.
, vol.57
, pp. 1493-1504
-
-
Srivastava, M.K.1
Bosch, J.J.2
Thompson, J.A.3
Ksander, B.R.4
Edelman, M.J.5
Ostrand-Rosenberg, S.6
-
60
-
-
75149123468
-
Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystineand cysteine
-
Srivastava, M. K. , Sinha, P. Clements, V. K. , Rodriguez, P. , and Ostrand-Rosenberg, S. (2010). Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystineand cysteine. Cancer Res 70: 68-77.
-
(2010)
Cancer Res
, vol.70
, pp. 68-77
-
-
Srivastava, M.K.1
Sinha, P.2
Clements, V.K.3
Rodriguez, P.4
Ostrand-Rosenberg, S.5
-
61
-
-
48649091348
-
STAT3: Animportant regulator of multiple cytokine functions
-
Stepkowski, S. M. , Chen, W. , Ross, J. A. , Nagy, Z. S. , and Kirken, R. A. (2008). STAT3: animportant regulator of multiple cytokine functions. Transplantation 85: 1372-1377.
-
(2008)
Transplantation
, vol.85
, pp. 1372-1377
-
-
Stepkowski, S.M.1
Chen, W.2
Ross, J.A.3
Nagy, Z.S.4
Kirken, R.A.5
-
62
-
-
68849128500
-
Therapeutic targeting of myeloid-derived suppressor cells
-
Ugel, S. , Delpozzo, F. , Desantis, G. , Papalini, F. , Simonato, F. , Sonda, N. , Zilio, S. , andBronte, V. (2009). Therapeutic targeting of myeloid-derived suppressor cells. CurrOpin Pharmacol 9: 470-481.
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 470-481
-
-
Ugel, S.1
Delpozzo, F.2
Desantis, G.3
Papalini, F.4
Simonato, F.5
Sonda, N.6
Zilio, S.7
Bronte, V.8
-
63
-
-
77951086882
-
5-Fluorouracil selectively killstumor-associated myeloid-derived suppressor cells resulting in enhanced T celldependentantitumor immunity
-
Vincent, J. , Mignot, G. , Chalmin, F. , Ladoire, S. , Bruchard, M. , Chevriaux, A. , Martin, F. ,Apetoh, L. , Rebe, C. , and Ghiringhelli, F. (2010). 5-Fluorouracil selectively killstumor-associated myeloid-derived suppressor cells resulting in enhanced T celldependentantitumor immunity. Cancer Res. 70: 3052-3061.
-
(2010)
Cancer Res.
, vol.70
, pp. 3052-3061
-
-
Vincent, J.1
Mignot, G.2
Chalmin, F.3
Ladoire, S.4
Bruchard, M.5
Chevriaux, A.6
Martin Apetoh F, L.7
Rebe, C.8
Ghiringhelli, F.9
-
64
-
-
81155131681
-
Tumor-derived G-CSFfacilitates neoplastic growth through a granulocytic myeloid-derived suppressor celldependentmechanism
-
Waight, J. D. , Hu, Q. , Miller, A. , Liu, S. , and Abrams, S. I. (2011). Tumor-derived G-CSFfacilitates neoplastic growth through a granulocytic myeloid-derived suppressor celldependentmechanism. PLoS One 6: e27690.
-
(2011)
PLoS One
, vol.6
-
-
Waight, J.D.1
Hu, Q.2
Miller, A.3
Liu, S.4
Abrams, S.I.5
-
65
-
-
78649586268
-
The biology of myeloid-derived suppressor cells the blessing and the curse of morphological and functional heterogeneity
-
Youn, J. I. , and Gabrilovich, D. L. (2010). The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. Eur. J. Immunol. 40: 2969-2975.
-
(2010)
Eur J Immunol
, vol.40
, pp. 2969-2975
-
-
Youn, J.I.1
Gabrilovich, D.L.2
-
66
-
-
80052194777
-
Increased circulating immunosuppressiveCD14( +)HLA-DR(-/low) cells correlate with clinical cancer stage andpathological grade in patients with bladder carcinoma
-
Yuan, X. K. , X. K. Zhao, Y. C. Xia, X. Zhu, and P. Xiao. 2011. Increased circulating immunosuppressiveCD14( +)HLA-DR(-/low) cells correlate with clinical cancer stage andpathological grade in patients with bladder carcinoma. J. Int. Med. Res. 39: 1381-1391.
-
(2011)
J. Int. Med. Res.
, vol.39
, pp. 1381-1391
-
-
Yuan, X.K.1
Zhao, X.K.2
Xia, Y.C.3
Zhu, X.4
Xiao, P.5
-
67
-
-
20244367914
-
Arginase-producing myeloid suppressor cells in renal cell carcinomapatients: A mechanism of tumor evasion
-
Zea, A. H. , Rodriguez, P. C. , Atkins, M. B. , Hernandez, C. , Signoretti, S. , Zabaleta, J. ,McDermott, D. , Quiceno, D. , Youmans, A. , O'Neill, A. , Mier, J. , and Ochoa, A. C. (2005). Arginase-producing myeloid suppressor cells in renal cell carcinomapatients: a mechanism of tumor evasion. Cancer Res 65: 3044-3048.
-
(2005)
Cancer Res
, vol.65
, pp. 3044-3048
-
-
Zea, A.H.1
Rodriguez, P.C.2
Atkins, M.B.3
Hernandez, C.4
Signoretti, S.5
Zabaleta, J.6
McDermott, D.7
Quiceno, D.8
Youmans, A.9
O'Neill, A.10
Mier, J.11
Ochoa, A.C.12
|