Egr-1 mediates chronic hypoxia-induced renal interstitial fibrosis via the PKC/ERK pathway

American Journal of Nephrology

Volumn 39, Issue 5, 2014, Pages 436-448

  Sun, Shiren ^a   Ning, Xiaoxuan ^a,b   Zhai, Ying ^a   Du, Rui ^a   Lu, Yuanyuan ^a   He, Lijie ^a   Li, Rong ^a   Wu, Weini ^a   Sun, Wenjuan ^a   Wang, Hanmin ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Egr 1; Hypoxia; PKC ERK; Renal fibrosis

Indexed keywords

CALVASCULIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR EGR 1; UVOMORULIN; 2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; CADHERIN; CALCIUM BINDING PROTEIN; CALPHOSTIN C; EARLY GROWTH RESPONSE FACTOR 1; EGR1 PROTEIN, HUMAN; FLAVONOID; FSP1 PROTEIN, HUMAN; NAPHTHALENE DERIVATIVE; PROTEIN KINASE C; PROTEIN KINASE INHIBITOR; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; TRANSCRIPTION FACTOR SNAIL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EXPERIMENTAL HYPOXIA; FIBROSING ALVEOLITIS; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VIVO STUDY; KIDNEY CELL; KIDNEY FIBROSIS; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RENAL INTERSTITIAL FIBROSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CELL HYPOXIA; CHEMISTRY; CHRONIC KIDNEY FAILURE; DRUG EFFECTS; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; FIBROSIS; GENETIC TRANSFECTION; GENETICS; KIDNEY TUBULE; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT; UPREGULATION; ANIMAL TISSUE; HYPOXIA; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTRACELLULAR SIGNALING; KIDNEY EPITHELIUM;

ANIMALS; CADHERINS; CALCIUM-BINDING PROTEINS; CELL HYPOXIA; CELLS, CULTURED; EARLY GROWTH RESPONSE PROTEIN 1; EPITHELIAL CELLS; EPITHELIAL-MESENCHYMAL TRANSITION; FIBROSIS; FLAVONOIDS; GENE KNOCKDOWN TECHNIQUES; HUMANS; KIDNEY TUBULES; MALE; MAP KINASE SIGNALING SYSTEM; NAPHTHALENES; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RENAL INSUFFICIENCY, CHRONIC; RNA, MESSENGER; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84899771102     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000362249     Document Type: Article

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