Effects of hypoxia on transcription factor expression in human monocytes and macrophages

Immunobiology

Volumn 213, Issue 9-10, 2008, Pages 899-908

  Elbarghati, Laila ^a   Murdoch, Craig ^b   Lewis, Claire E ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Hypoxia; Macrophages; Monocytes; Transcription factors

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; EARLY GROWTH RESPONSE FACTOR 1; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; TRANSCRIPTION FACTOR;

ARTICLE; CELL DIFFERENTIATION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EXPERIMENTAL NEOPLASM; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; ISCHEMIA; MACROPHAGE; MONOCYTE; NECROSIS; PRIORITY JOURNAL; PROTEIN TRANSPORT; REOXYGENATION; UPREGULATION;

ACTIVATING TRANSCRIPTION FACTOR 4; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELLS, CULTURED; EARLY GROWTH RESPONSE PROTEIN 1; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MACROPHAGES; MONOCYTES; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 52749087157     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2008.07.016     Document Type: Article

References (45)

1. Ameri K., Lewis C.E., Raida M., Sowter H., Hai T., and Harris A.L. Anoxic induction of ATF-4 via HIF-1-independent pathways of protein stabilization in human cancer cells. Blood 103 (2004) 1876-1882
2. Battaglia F., Delfino S., Merello E., Puppo M., Piva R., Varesio L., and Bosco M.C. Hypoxia transcriptionally induces macrophage-inflammatory protein-3α/CCL-20 in primary human mononuclear phagocytes through nuclear factor κB. J. Leukocyte Biol. 83 (2008) 648-662
3. Blais J.D., Filipenko V., Bi M., Harding H.P., Ron D., Koumenis C., Wouters B.G., and Bell J.C. Activating transcription factor 4 is translationally regulated by hypoxic stress. Mol. Cell. Biol. 24 (2004) 7469-7482
4. Burke B., Tang N., Corke K.P., Tazzyman D., Ameri K., Wells M., and Lewis C.E. Expression of HIF-1α by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy. J. Pathol. 196 (2002) 204-212
5. Cibelli G., Schoch S., and Thiel G. Nuclear targeting of cAMP response element binding protein 2 (CREB2). Eur. J. Cell Biol. 78 (1999) 642-649
6. Cramer T., Yamanishi Y., Clausen B.E., Forster I., Pawlinski R., Mackman N., Haase V.H., Jaenisch R., Corr M., Nizet V., Firestein G.S., Gerber H.P., Ferrara N., and Johnson R.S. HIF-1α is essential for myeloid cell-mediated inflammation. Cell 112 (2003) 645-657
7. D'Angelo G., Duplan E., Boyer N., Vigne P., and Frelin C. Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation. J. Biol. Chem. 278 (2003) 38183-38187
8. Estes S.D., Stoler D.L., and Anderson G.R. Normal fibroblasts induce the C/EBP beta and ATF-4 bZIP transcription factors in response to anoxia. Exp. Cell Res. 220 (1995) 47-54
9. Fong C.C., Zhang Q., Shi Y.F., Wu R.S., Fong W.F., and Yang M. Effect of hypoxia on RAW264.7 macrophages apoptosis and signaling. Toxicology 235 (2007) 52-61
10. Hara S., Hamada J., Kobayashi C., Kondo Y., and Imura N. Expression and characterization of hypoxia-inducible factor (HIF)-3α in human kidney: suppression of HIF-mediated gene expression by HIF-3α. Biochem. Biophys. Res. Commun. 287 (2001) 808-813
11. Harmey J.H., Dimitriadis E., Kay E., Redmond H.P., and Bouchier-Hayes D. Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor β-1. Ann. Surg. Oncol. 5 (1998) 271-278
12. Harris A.L. Hypoxia - a key regulatory factor in tumour growth. Nat. Rev. Cancer. 2 (2002) 38-47
13. Hehlgans T., Seitz C., Lewis C., and Mannel D.N. Hypoxic up-regulation of TNF receptor type 2 expression involves NF-IL-6 and is independent of HIF-1 or HIF-2. J. Interferon Cytokine Res. 21 (2001) 757-762
14. Heidbreder M., Frohlich F., Johren O., Dendorfer A., Qadri F., and Dominiak P. Hypoxia rapidly activates HIF-3α mRNA expression. FASEB J. 17 (2003) U432-U450
15. Holmquist L., Jogi A., and Pahlman S. Phenotypic persistence after reoxygenation of hypoxic neuroblastoma cells. Int. J. Cancer 116 (2005) 218-225
16. Jiang B.H., Rue E., Wang G.L., Roe R., and Semenza G.L. Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1. J. Biol. Chem. 271 (1996) 17771-17778
17. Kharbanda S., Nakamura T., Stone R., Hass R., Bernstein S., Datta R., Sukhatme V.P., and Kufe D. Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation. J. Clin. Invest. 88 (1991) 571-577
18. Koong A.C., Chen E.Y., and Giaccia A.J. Hypoxia causes the activation of nuclear factor κB through the phosphorylation of IκB alpha on tyrosine residues. Cancer Res. 54 (1994) 1425-1430
19. Krauss S.W., Chen C., Penman S., and Heald R. Nuclear actin and protein 4.1: essential interactions during nuclear assembly in vitro. Proc. Natl. Acad. Sci. USA 100 (2003) 10752-10757
20. Leek R.D., Lewis C.E., Whitehouse R., Greenall M., Clarke J., and Harris A.L. Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res. 56 (1996) 4625-4629
21. Lewis C.E., and Murdoch C. Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies. Am. J. Pathol. 167 (2005) 627-635
22. Lewis C.E., and Pollard J.W. Distinct role of macrophages in different tumor microenvironments. Cancer Res. 66 (2006) 605-612
23. Lewis J.S., Lee J.A., Underwood J.C., Harris A.L., and Lewis C.E. Macrophage responses to hypoxia: relevance to disease mechanisms. J. Leukocyte Biol. 66 (1999) 889-900
24. Lewis J.S., Landers R.J., Underwood J.C., Harris A.L., and Lewis C.E. Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas. J. Pathol. 192 (2000) 150-158
25. Negus R.P., Stamp G.W., Hadley J., and Balkwill F.R. Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines. Am. J. Pathol. 150 (1997) 1723-1734
26. Oikawa M., Abe M., Kurosawa H., Hida W., Shirato K., and Sato Y. Hypoxia induces transcription factor ETS-1 via the activity of hypoxia-inducible factor-1. Biochem. Biophys. Res. Commun. 289 (2001) 39-43
27. Onita T., Ji P.G., Xuan J.W., Sakai H., Kanetake H., Maxwell P.H., Fong G.H., Gabril M.Y., Moussa M., and Chin J.L. Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2α correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer. Clin. Cancer Res. 8 (2002) 471-480
28. Pan Z., Hetherington C.J., and Zhang D.E. CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor β signaling in monocyte development. J. Biol. Chem. 274 (1999) 23242-23248
29. Park H.J., Lee Y.W., Hennig B., and Toborek M. Linoleic acid-induced VCAM-1 expression in human microvascular endothelial cells is mediated by the NFκB-dependent pathway. Nutr. Cancer 41 (2001) 126-134
30. Peyssonnaux C., Datta V., Cramer T., Doedens A., Theodorakis E.A., Gallo R.L., Hurtado-Ziola N., Nizet V., and Johnson R.S. HIF-1α expression regulates the bactericidal capacity of phagocytes. J. Clin. Invest. 115 (2005) 1806-1815
31. Rehli M., Krause S.W., Kreutz M., and Andreesen R. Carboxypeptidase M is identical to the MAX.1 antigen and its expression is associated with monocyte to macrophage differentiation. J. Biol. Chem. 270 (1995) 15644-15649
32. Schmitz M.L., and Baeuerle P.A. The p65 subunit is responsible for the strong transcription activating potential of NFκB. EMBO J. 10 (1991) 3805-3817
33. Scott L.M., Civin C.I., Rorth P., and Friedman A.D. A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells. Blood 80 (1992) 1725-1735
34. Semenza G.L. HIF-1 and human disease: one highly involved factor. Genes Dev. 14 (2000) 1983-1991
35. Shweiki D., Itin A., Soffer D., and Keshet E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359 (1992) 843-845
36. Siu F., Bain P.J., LeBlanc-Chaffin R., Chen H., and Kilberg M.S. ATF4 is a mediator of the nutrient-sensing response pathway that activates the human asparagine synthetase gene. J. Biol. Chem. 277 (2002) 24120-24127
37. Talks K.L., Turley H., Gatter K.C., Maxwell P.H., Pugh C.W., Ratcliffe P.J., and Harris A.L. The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am. J. Pathol. 157 (2000) 411-421
38. Uchida T., Rossignol F., Matthay M.A., Mounier R., Couette S., Clottes E., and Clerici C. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1α and HIF-2α expression in lung epithelial cells: implication of natural antisense HIF-1α. J. Biol. Chem. 279 (2004) 14871-14878
39. Vaupel P., Thews O., and Hoeckel M. Treatment resistance of solid tumors: role of hypoxia and anemia. Med. Oncol. 18 (2001) 243-259
40. White J.R., Harris R.A., Lee S.R., Craigon M.H., Binley K., Price T., Beard G.L., Mundy C.R., and Naylor S. Genetic amplification of the transcriptional response to hypoxia as a novel means of identifying regulators of angiogenesis. Genomics 83 (2004) 1-8
41. Wiesener M.S., Turley H., Allen W.E., Willam C., Eckardt K.U., Talks K.L., Wood S.M., Gatter K.C., Harris A.L., Pugh C.W., Ratcliffe P.J., and Maxwell P.H. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1α. Blood 92 (1998) 2260-2268
42. Yamashiro S., Takeya M., Nishi T., Kuratsu J., Yoshimura T., Ushio Y., and Takahashi K. Tumor-derived monocyte chemoattractant protein-1 induces intratumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors. Am. J. Pathol. 145 (1994) 856-867
43. Yan S.F., Tritto I., Pinsky D., Liao H., Huang J., Fuller G., Brett J., May L., and Stern D. Induction of interleukin 6 (IL-6) by hypoxia in vascular cells. Central role of the binding site for nuclear factor-IL-6. J. Biol. Chem. 270 (1995) 11463-11471
44. Yan S.F., Lu J., Zou Y.S., Soh-Won J., Cohen D.M., Buttrick P.M., Cooper D.R., Steinberg S.F., Mackman N., Pinsky D.J., and Stern D.M. Hypoxia-associated induction of early growth response-1 gene expression. J. Biol. Chem. 274 (1999) 15030-15040
45. Zhong H., and Simons J.W. Direct comparison of GAPDH, β-actin, cyclophilin, and 28S rRNA as internal standards for quantifying RNA levels under hypoxia. Biochem. Biophys. Res. Commun. 259 (1999) 523-526