Metformin inhibits inflammatory response via AMPK-PTEN pathway in vascular smooth muscle cells

Biochemical and Biophysical Research Communications

Volumn 425, Issue 4, 2012, Pages 866-872

  Kim, Sun Ae ^a   Choi, Hyoung Chul ^a  

^a Yeungnam University College of Medicine   (South Korea)

Author keywords

AMPK; Inflammation; PTEN; VSMC

Indexed keywords

CYCLOOXYGENASE 2; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; METFORMIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INFLAMMATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; CELLS, CULTURED; HYPOGLYCEMIC AGENTS; INFLAMMATION; MALE; METFORMIN; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PROTEIN KINASES; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84865956222     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.07.165     Document Type: Article

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