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Volumn 289, Issue 18, 2014, Pages 12896-12907

Ischemia-like Oxygen and Glucose Deprivation Mediates Down-regulation of Cell Surface γ-Aminobutyric AcidB Receptors via the Endoplasmic Reticulum (ER) Stress-induced Transcription Factor CCAAT/Enhancer-binding Protein (C/EBP)-homologous Protein (CHOP)

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EID: 84899753156     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.550517     Document Type: Article
Times cited : (43)

References (48)
  • 1
    • 3042546515 scopus 로고    scopus 로고
    • Molecular structure and physiological functions ofgabab receptors
    • Bettler, B., Kaupmann, K., Mosbacher, J., and Gassmann, M. (2004) Molecular structure and physiological functions ofGABAB receptors. Physiol. Rev. 84, 835-867
    • (2004) Physiol. Rev. , vol.84 , pp. 835-867
    • Bettler, B.1    Kaupmann, K.2    Mosbacher, J.3    Gassmann, M.4
  • 2
    • 0033667466 scopus 로고    scopus 로고
    • A trafficking checkpoint controls gabab receptor heterodimerization
    • Margeta-Mitrovic, M., Jan, Y. N., and Jan, L. Y. (2000) A trafficking checkpoint controls GABAB receptor heterodimerization. Neuron 27, 97-106
    • (2000) Neuron , vol.27 , pp. 97-106
    • Margeta-Mitrovic, M.1    Jan, Y.N.2    Jan, L.Y.3
  • 5
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton, P. (1999) Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568
    • (1999) Physiol. Rev. , vol.79 , pp. 1431-1568
    • Lipton, P.1
  • 6
    • 0035044262 scopus 로고    scopus 로고
    • Aminobutyric acid(a) neurotransmission and cerebral ischemia
    • Schwartz-Bloom, R. D., and Sah, R. (2001)-Aminobutyric acid(A) neurotransmission and cerebral ischemia. J. Neurochem. 77, 353-371
    • (2001) J. Neurochem. , vol.77 , pp. 353-371
    • Schwartz-Bloom, R.D.1    Sah, R.2
  • 7
    • 31944435395 scopus 로고    scopus 로고
    • Gabab receptor expression and cellular localization in gerbil hippocampus after transient global ischemia
    • Vollenweider, F., Bendfeldt, K., Maetzler, W., Otten, U., and Nitsch, C. (2006) GABAB receptor expression and cellular localization in gerbil hippocampus after transient global ischemia. Neurosci. Lett. 395, 118-123
    • (2006) Neurosci. Lett. , vol.395 , pp. 118-123
    • Vollenweider, F.1    Bendfeldt, K.2    Maetzler, W.3    Otten, U.4    Nitsch, C.5
  • 8
    • 79955725083 scopus 로고    scopus 로고
    • Mild hypothermia suppresses calcium-sensing receptor (casr) induction following forebrain ischemia while increasing gabab receptor 1 (gabab-r1) expression
    • Kim, J. Y., Kim, N., Yenari, M. A., and Chang, W. (2011) Mild hypothermia suppresses calcium-sensing receptor (CaSR) induction following forebrain ischemia while increasing GABAB receptor 1 (GABAB-R1) expression. Transl. Stroke Res. 2, 195-201
    • (2011) Transl. Stroke Res. , vol.2 , pp. 195-201
    • Kim, J.Y.1    Kim, N.2    Yenari, M.A.3    Chang, W.4
  • 9
    • 0032924871 scopus 로고    scopus 로고
    • Decreased hippocampal expression, but not functionality, of gabab receptors after transient cerebral ischemia in rats
    • Francis, J., Zhang, Y., Ho, W., Wallace, M. C., Zhang, L., and Eubanks, J. H. (1999) Decreased hippocampal expression, but not functionality, of GABAB receptors after transient cerebral ischemia in rats. J. Neurochem. 72, 87-94
    • (1999) J. Neurochem. , vol.72 , pp. 87-94
    • Francis, J.1    Zhang, Y.2    Ho, W.3    Wallace, M.C.4    Zhang, L.5    Eubanks, J.H.6
  • 10
    • 67349174608 scopus 로고    scopus 로고
    • Ischaemia differentially regulates gabab receptor subunits in organotypic hippocampal slice cultures
    • Cimarosti, H., Kantamneni, S., and Henley, J. M. (2009) Ischaemia differentially regulates GABAB receptor subunits in organotypic hippocampal slice cultures. Neuropharmacology 56, 1088-1096
    • (2009) Neuropharmacology , vol.56 , pp. 1088-1096
    • Cimarosti, H.1    Kantamneni, S.2    Henley, J.M.3
  • 11
    • 0037085941 scopus 로고    scopus 로고
    • Baclofen is neuroprotective and prevents loss of calcium/calmodulin- dependent protein kinase ii immunoreactivity in the ischemic gerbil hippocampus
    • Babcock, A. M., Everingham, A., Paden, C. M., and Kimura, M. (2002) Baclofen is neuroprotective and prevents loss of calcium/calmodulin-dependent protein kinase II immunoreactivity in the ischemic gerbil hippocampus. J. Neurosci. Res. 67, 804-811
    • (2002) J. Neurosci. Res. , vol.67 , pp. 804-811
    • Babcock, A.M.1    Everingham, A.2    Paden, C.M.3    Kimura, M.4
  • 12
    • 28444475223 scopus 로고    scopus 로고
    • Ischemic preconditioning ameliorates excitotoxicity by shifting glutamate/-aminobutyric acid release and biosynthesis
    • Dave, K. R., Lange-Asschenfeldt, C., Raval, A. P., Prado, R., Busto, R., Saul, I., and Pérez-Pinzón, M. A. (2005) Ischemic preconditioning ameliorates excitotoxicity by shifting glutamate/-aminobutyric acid release and biosynthesis. J. Neurosci. Res. 82, 665-673
    • (2005) J. Neurosci. Res. , vol.82 , pp. 665-673
    • Dave, K.R.1    Lange-Asschenfeldt, C.2    Raval, A.P.3    Prado, R.4    Busto, R.5    Saul, I.6    Pérez-Pinzón, M.A.7
  • 13
    • 0031259076 scopus 로고    scopus 로고
    • High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: A quantal bioassay study using the intraluminal suture occlusion method
    • Jackson-Friedman, C., Lyden, P. D., Nunez, S., Jin, A., and Zweifler, R. (1997) High dose baclofen is neuroprotective but also causes intracerebral hemorrhage: a quantal bioassay study using the intraluminal suture occlusion method. Exp. Neurol. 147, 346-352
    • (1997) Exp. Neurol. , vol.147 , pp. 346-352
    • Jackson-Friedman, C.1    Lyden, P.D.2    Nunez, S.3    Jin, A.4    Zweifler, R.5
  • 14
    • 0035122516 scopus 로고    scopus 로고
    • Additivity and independence of neuroprotective effects of gabaa and gabab receptor agonists in complete global cerebral ischemia
    • Kulinskii, V. I., and Mikhel'son, G. V. (2000) Additivity and independence of neuroprotective effects of GABAA and GABAB receptor agonists in complete global cerebral ischemia. Bull. Exp. Biol. Med. 130, 772-774
    • (2000) Bull. Exp. Biol. Med. , Issue.130 , pp. 772-774
    • Kulinskii, V.1    Mikhel'son, G.2
  • 15
    • 41449086952 scopus 로고    scopus 로고
    • Co-activation of gaba receptors inhibits the jnk3 apoptotic pathway via the disassembly of the glur6- psd95-mlk3 signaling module in cerebral ischemic-reperfusion
    • Han, D., Zhang, Q. G., Yong-Liu, Li C., Zong, Y. Y., Yu, C. Z., Wang, W., Yan, J. Z., and Zhang, G. Y. (2008) Co-activation of GABA receptors inhibits the JNK3 apoptotic pathway via the disassembly of the GluR6- PSD95-MLK3 signaling module in cerebral ischemic-reperfusion. FEBS Lett. 582, 1298-1306
    • (2008) FEBS Lett. , vol.582 , pp. 1298-1306
    • Han, D.1    Zhang, Q.G.2    Yong-Liu Li, C.3    Zong, Y.Y.4    Yu, C.Z.5    Wang, W.6    Yan, J.Z.7    Zhang, G.Y.8
  • 16
    • 0028923159 scopus 로고
    • Baclofen is cytoprotective to cerebral ischemia in gerbils
    • Lal, S., Shuaib, A., and Ijaz, S. (1995) Baclofen is cytoprotective to cerebral ischemia in gerbils. Neurochem. Res. 20, 115-119
    • (1995) Neurochem. Res. , vol.20 , pp. 115-119
    • Lal, S.1    Shuaib, A.2    Ijaz, S.3
  • 17
    • 42749097879 scopus 로고    scopus 로고
    • Additive neuroprotection of gabaa and gabab receptor agonists in cerebral ischemic injury via pi-3k/akt pathway inhibiting the ask1-jnk cascade
    • Xu, J., Li, C., Yin, X. H., and Zhang, G. Y. (2008) Additive neuroprotection of GABAA and GABAB receptor agonists in cerebral ischemic injury via PI-3K/Akt pathway inhibiting the ASK1-JNK cascade. Neuropharmacology 54, 1029-1040
    • (2008) Neuropharmacology , vol.54 , pp. 1029-1040
    • Xu, J.1    Li, C.2    Yin, X.H.3    Zhang, G.Y.4
  • 18
    • 57049115942 scopus 로고    scopus 로고
    • Neuroprotection of-aminobutyric acid receptor agonists via enhancing neuronal nitric oxide synthase (ser847) phosphorylation through increased neuronal nitric oxide synthase and psd95 interaction and inhibited protein phosphatase activity in cerebral ischemia
    • Zhou, C., Li, C., Yu, H. M., Zhang, F., Han, D., and Zhang, G. Y. (2008) Neuroprotection of-aminobutyric acid receptor agonists via enhancing neuronal nitric oxide synthase (Ser847) phosphorylation through increased neuronal nitric oxide synthase and PSD95 interaction and inhibited protein phosphatase activity in cerebral ischemia. J. Neurosci. Res. 86, 2973-2983
    • (2008) J. Neurosci. Res. , vol.86 , pp. 2973-2983
    • Zhou, C.1    Li, C.2    Yu, H.M.3    Zhang, F.4    Han, D.5    Zhang, G.Y.6
  • 19
    • 36849040517 scopus 로고    scopus 로고
    • Activation of gaba receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of nr2a by src after cerebral ischemia and reperfusion
    • Zhang, F., Li, C., Wang, R., Han, D., Zhang, Q. G., Zhou, C., Yu, H. M., and Zhang, G. Y. (2007) Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion. Neuroscience 150, 938-949
    • (2007) Neuroscience , vol.150 , pp. 938-949
    • Zhang, F.1    Li, C.2    Wang, R.3    Han, D.4    Zhang, Q.G.5    Zhou, C.6    Yu, H.M.7    Zhang, G.Y.8
  • 20
    • 57049117856 scopus 로고    scopus 로고
    • Cell death and endoplasmic reticulum stress: Disease relevance and therapeutic opportunities
    • Kim, I., Xu, W., and Reed, J. C. (2008) Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat. Rev. Drug. Discov. 7, 1013-1030
    • (2008) Nat. Rev. Drug. Discov. , vol.7 , pp. 1013-1030
    • Kim, I.1    Xu, W.2    Reed, J.C.3
  • 21
    • 1842843855 scopus 로고    scopus 로고
    • Roles of chop/gadd153 in endoplasmic reticulum stress
    • Oyadomari, S., and Mori, M. (2004) Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11, 381-389
    • (2004) Cell Death Differ. , vol.11 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 22
    • 25844489095 scopus 로고    scopus 로고
    • Subtype-selective interaction with the transcription factor ccaat/enhancer-binding protein (c/ebp) homologous protein (chop) regulates cell surface expression of gabab receptors
    • Sauter, K., Grampp, T., Fritschy, J. M., Kaupmann, K., Bettler, B., Mohler, H., and Benke, D. (2005) Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABAB receptors. J. Biol. Chem. 280, 33566-33572
    • (2005) J. Biol. Chem. , vol.280 , pp. 33566-33572
    • Sauter, K.1    Grampp, T.2    Fritschy, J.M.3    Kaupmann, K.4    Bettler, B.5    Mohler, H.6    Benke, D.7
  • 23
    • 0033578638 scopus 로고    scopus 로고
    • Aminobutyric acid type b receptor splice variant proteins gbr1a and gbr1b are both associated with gbr2 in situ and display differential regional and subcellular distribution
    • Benke, D., Honer, M., Michel, C., Bettler, B., and Mohler, H. (1999)-Aminobutyric acid type B receptor splice variant proteins GBR1a and GBR1b are both associated with GBR2 in situ and display differential regional and subcellular distribution. J. Biol. Chem. 274, 27323-27330
    • (1999) J. Biol. Chem. , vol.274 , pp. 27323-27330
    • Benke, D.1    Honer, M.2    Michel, C.3    Bettler, B.4    Mohler, H.5
  • 25
    • 0025922807 scopus 로고
    • Gabaa receptors display association of 2-subunit with-1- and-2/3- subunits
    • Benke, D., Mertens, S., Trzeciak, A., Gillessen, D., and Mohler, H. (1991) GABAA receptors display association of 2-subunit with-1- and-2/3- subunits. J. Biol. Chem. 266, 4478-4483
    • (1991) J. Biol. Chem. , vol.266 , pp. 4478-4483
    • Benke, D.1    Mertens, S.2    Trzeciak, A.3    Gillessen, D.4    Mohler, H.5
  • 26
    • 56249127867 scopus 로고    scopus 로고
    • Constitutive, agonist-accelerated, recycling and lysosomal degradation of gabab receptors in cortical neurons
    • Grampp, T., Notz, V., Broll, I., Fischer, N., and Benke, D. (2008) Constitutive, agonist-accelerated, recycling and lysosomal degradation of GABAB receptors in cortical neurons. Mol. Cell. Neurosci. 39, 628-637
    • (2008) Mol. Cell. Neurosci. , vol.39 , pp. 628-637
    • Grampp, T.1    Notz, V.2    Broll, I.3    Fischer, N.4    Benke, D.5
  • 28
    • 0037088589 scopus 로고    scopus 로고
    • Erk activation by g-protein-coupled receptors in mouse brain is receptor identity-specific
    • Vanhoose, A. M., Emery, M., Jimenez, L., and Winder, D. G. (2002) ERK activation by G-protein-coupled receptors in mouse brain is receptor identity-specific. J. Biol. Chem. 277, 9049-9053
    • (2002) J. Biol. Chem. , vol.277 , pp. 9049-9053
    • Vanhoose, A.M.1    Emery, M.2    Jimenez, L.3    Winder, D.G.4
  • 29
    • 0142180127 scopus 로고    scopus 로고
    • Hydroxybutyrate reduces mitogen-activated protein kinase phosphorylation via gabab receptor activation in mouse frontal cortex and hippocampus
    • Ren, X., and Mody, I. (2003)-Hydroxybutyrate reduces mitogen-activated protein kinase phosphorylation via GABAB receptor activation in mouse frontal cortex and hippocampus. J. Biol. Chem. 278, 42006-42011
    • (2003) J. Biol. Chem. , vol.278 , pp. 42006-42011
    • Ren, X.1    Mody, I.2
  • 30
    • 34447621270 scopus 로고    scopus 로고
    • Dominant role of gabab2 and g+ for gabab receptormediated- erk1/2/creb pathway in cerebellar neurons
    • Tu, H., Rondard, P., Xu, C., Bertaso, F., Cao, F., Zhang, X., Pin, J. P., and Liu, J. (2007) Dominant role of GABAB2 and G+ for GABAB receptormediated- ERK1/2/CREB pathway in cerebellar neurons. Cell Signal. 19, 1996-2002
    • (2007) Cell Signal. , vol.19 , pp. 1996-2002
    • Tu, H.1    Rondard, P.2    Xu, C.3    Bertaso, F.4    Cao, F.5    Zhang, X.6    Pin, J.P.7    Liu, J.8
  • 31
    • 84858158942 scopus 로고    scopus 로고
    • Gabab receptor-mediated erk1/2 phosphorylation via a direct interaction with cav1.3 channels
    • Im, B. H., and Rhim, H. (2012) GABAB receptor-mediated ERK1/2 phosphorylation via a direct interaction with CaV1.3 channels. Neurosci. Lett. 513, 89-94
    • (2012) Neurosci. Lett. , vol.513 , pp. 89-94
    • Im, B.H.1    Rhim, H.2
  • 34
    • 84896261772 scopus 로고    scopus 로고
    • Proteasomal degradation of-aminobutyric acidb receptors is mediated by the interaction of the gabab2 c terminus with the proteasomal atpase rtp6 and regulated by neuronal activity
    • Zemoura, K., and Benke, D. (2014) Proteasomal degradation of-aminobutyric acidB receptors is mediated by the interaction of the GABAB2 C terminus with the proteasomal ATPase Rtp6 and regulated by neuronal activity. J. Biol. Chem. 289, 7738-7746
    • (2014) J. Biol. Chem. , vol.289 , pp. 7738-7746
    • Zemoura, K.1    Benke, D.2
  • 35
    • 0027298139 scopus 로고
    • Disturbances of cerebral protein synthesis and ischemic cell death
    • Hossmann, K. A. (1993) Disturbances of cerebral protein synthesis and ischemic cell death. Prog. Brain Res. 96, 161-177
    • (1993) Prog. Brain Res. , vol.96 , pp. 161-177
    • Hossmann, K.A.1
  • 36
    • 0032619914 scopus 로고    scopus 로고
    • Disturbance of endoplasmic reticulum functions: A key mechanism underlying cell damage?
    • Paschen, W., and Doutheil, J. (1999) Disturbance of endoplasmic reticulum functions: a key mechanism underlying cell damage? Acta Neurochir. Suppl. 73, 1-5
    • (1999) Acta Neurochir. Suppl. , vol.73 , pp. 1-5
    • Paschen, W.1    Doutheil, J.2
  • 37
    • 63149183734 scopus 로고    scopus 로고
    • Apolipoprotein e-deficient mice are more vulnerable to er stress after transient forebrain ischemia
    • Osada, N., Kosuge, Y., Kihara, T., Ishige, K., and Ito, Y. (2009) Apolipoprotein E-deficient mice are more vulnerable to ER stress after transient forebrain ischemia. Neurochem. Int. 54, 403-409
    • (2009) Neurochem. Int. , vol.54 , pp. 403-409
    • Osada, N.1    Kosuge, Y.2    Kihara, T.3    Ishige, K.4    Ito, Y.5
  • 38
    • 77953539363 scopus 로고    scopus 로고
    • Characterization of neuronal and astroglial responses to er stress in the hippocampal ca1 area in mice following transient forebrain ischemia
    • Osada, N., Kosuge, Y., Ishige, K., and Ito, Y. (2010) Characterization of neuronal and astroglial responses to ER stress in the hippocampal CA1 area in mice following transient forebrain ischemia. Neurochem. Int. 57, 1-7
    • (2010) Neurochem. Int. , vol.57 , pp. 1-7
    • Osada, N.1    Kosuge, Y.2    Ishige, K.3    Ito, Y.4
  • 39
    • 1842854719 scopus 로고    scopus 로고
    • Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving chop
    • Tajiri, S., Oyadomari, S., Yano, S., Morioka, M., Gotoh, T., Hamada, J.-I., Ushio, Y., and Mori, M. (2004) Ischemia-induced neuronal cell death is mediated by the endoplasmic reticulum stress pathway involving CHOP. Cell Death Differ. 11, 403-415
    • (2004) Cell Death Differ. , vol.11 , pp. 403-415
    • Tajiri, S.1    Oyadomari, S.2    Yano, S.3    Morioka, M.4    Gotoh, T.5    Hamada, J.-I.6    Ushio, Y.7    Mori, M.8
  • 40
    • 0032544514 scopus 로고    scopus 로고
    • Activation of gadd153 expression through transient cerebral ischemia: Evidence that ischemia causes endoplasmic reticulum dysfunction
    • Paschen, W., Gissel, C., Linden, T., Althausen, S., and Doutheil, J. (1998) Activation of Gadd153 expression through transient cerebral ischemia: evidence that ischemia causes endoplasmic reticulum dysfunction. Mol. Brain Res. 60, 115-122
    • (1998) Mol. Brain Res. , vol.60 , pp. 115-122
    • Paschen, W.1    Gissel, C.2    Linden, T.3    Althausen, S.4    Doutheil, J.5
  • 41
    • 37849026711 scopus 로고    scopus 로고
    • Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil
    • Oida, Y., Shimazawa, M., Imaizumi, K., and Hara, H. (2008) Involvement of endoplasmic reticulum stress in the neuronal death induced by transient forebrain ischemia in gerbil. Neuroscience 151, 111-119
    • (2008) Neuroscience , vol.151 , pp. 111-119
    • Oida, Y.1    Shimazawa, M.2    Imaizumi, K.3    Hara, H.4
  • 42
    • 34547128859 scopus 로고    scopus 로고
    • Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice
    • Morimoto, N., Oida, Y., Shimazawa, M., Miura, M., Kudo, T., Imaizumi, K., and Hara, H. (2007) Involvement of endoplasmic reticulum stress after middle cerebral artery occlusion in mice. Neuroscience 147, 957-967
    • (2007) Neuroscience , vol.147 , pp. 957-967
    • Morimoto, N.1    Oida, Y.2    Shimazawa, M.3    Miura, M.4    Kudo, T.5    Imaizumi, K.6    Hara, H.7
  • 44
    • 0036022403 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-mediated apoptosis in pancreatic-cells
    • Oyadomari, S., Araki, E., and Mori, M. (2002) Endoplasmic reticulum stress-mediated apoptosis in pancreatic-cells. Apoptosis 7, 335-345
    • (2002) Apoptosis , vol.7 , pp. 335-345
    • Oyadomari, S.1    Araki, E.2    Mori, M.3
  • 45
    • 0032054744 scopus 로고    scopus 로고
    • Chop is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
    • Zinszner, H., Kuroda, M., Wang, X., Batchvarova, N., Lightfoot, R. T., Remotti, H., Stevens, J. L., and Ron, D. (1998) CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 12, 982-995
    • (1998) Genes Dev. , vol.12 , pp. 982-995
    • Zinszner, H.1    Kuroda, M.2    Wang, X.3    Batchvarova, N.4    Lightfoot, R.T.5    Remotti, H.6    Stevens, J.L.7    Ron, D.8
  • 46
    • 0026050850 scopus 로고
    • Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum ca-atpase family of calcium pumps
    • Lytton, J., Westlin, M., and Hanley, M. R. (1991) Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J. Biol. Chem. 266, 17067-17071
    • (1991) J. Biol. Chem. , vol.266 , pp. 17067-17071
    • Lytton, J.1    Westlin, M.2    Hanley, M.R.3
  • 47
    • 61449210006 scopus 로고    scopus 로고
    • Identification of a novel region of the gabab2 c-terminus that regulates surface expression and neuronal targeting of the gabab receptor
    • Pooler, A. M., Gray, A. G., and McIlhinney, R. A. (2009) Identification of a novel region of the GABAB2 C-terminus that regulates surface expression and neuronal targeting of the GABAB receptor. Eur. J. Neurosci. 29, 869-878
    • (2009) Eur. J. Neurosci. , vol.29 , pp. 869-878
    • Pooler, A.M.1    Gray, A.G.2    McIlhinney, R.A.3
  • 48
    • 84863981333 scopus 로고    scopus 로고
    • The role of glutamate in neuronal ischemic injury: The role of spark in fire
    • Kostandy, B. B. (2012) The role of glutamate in neuronal ischemic injury: the role of spark in fire. Neurol. Sci. 33, 223-237
    • (2012) Neurol. Sci. , vol.33 , pp. 223-237
    • Kostandy, B.B.1


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