Co-activation of GABA receptors inhibits the JNK3 apoptotic pathway via the disassembly of the GluR6-PSD95-MLK3 signaling module in cerebral ischemic-reperfusion

FEBS Letters

Volumn 582, Issue 9, 2008, Pages 1298-1306

  Han, Dong ^a   Zhang, Quan Guang ^a   Yong Liu, ^a   Li, Chong ^a   Zong, Yan Yan ^a   Yu, Chang Zhou ^a   Wang, Wei ^a   Yan, Jing Zhi ^a   Zhang, Guang Yi ^a  

^a XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Baclofen; Cerebral ischemia; JNK pathway; Muscimol; Neuroprotection

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; BACLOFEN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; MIXED LINEAGE KINASE 3; MUSCIMOL; PROTEIN JNK3; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; MALE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; BACLOFEN; BRAIN ISCHEMIA; GABA AGONISTS; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MAP KINASE KINASE KINASES; MEMBRANE PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASE 10; MUSCIMOL; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA; RECEPTORS, KAINIC ACID; REPERFUSION INJURY; SIGNAL TRANSDUCTION;

EID: 41449086952     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.02.044     Document Type: Article

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