Proteasomal degradation of γ-aminobutyric acidB receptors is mediated by the interaction of the GABAB2 C terminus with the proteasomal ATPase Rtp6 and regulated by neuronal activity

Journal of Biological Chemistry

Volumn 289, Issue 11, 2014, Pages 7738-7746

  Zemoura, Khaled ^a,b   Benke, Dietmar ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Neuroscience Center Zurich and Division of Neurosurgery   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELL MEMBRANES; MACHINERY;

AMINOBUTYRIC ACIDS; CELL SURFACE EXPRESSION; ENDOPLASMIC RETICULUM; INTERACTION LEVELS; NEURONAL ACTIVITIES; NEURONAL PLASTICITY; PROTEASOMAL DEGRADATION; PROTEIN DEGRADATION;

NEURONS;

4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR 2; ADENOSINE TRIPHOSPHATASE; PROTEASOME; PROTEIN RTP6; UNCLASSIFIED DRUG;

ARTICLE; BRAIN NERVE CELL; CARBOXY TERMINAL SEQUENCE; CELL ACTIVITY; CELL MIGRATION; CELL SURFACE; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENZYME ACTIVITY; ENZYME REGULATION; HOMEOSTASIS; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR MECHANICS; NERVE CELL PLASTICITY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SYNTHESIS REGULATION; REGULATORY MECHANISM;

ENDOPLASMIC RETICULUM (ER); ER-ASSOCIATED DEGRADATION; GABA RECEPTORS; PROTEASOME; UBIQUITIN;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE TRIPHOSPHATASES; ANIMALS; CELL MEMBRANE; ENDOPLASMIC RETICULUM; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HEK293 CELLS; HOMEOSTASIS; HUMANS; LIM DOMAIN PROTEINS; LYSINE; MICE; MUTATION; NEURONAL PLASTICITY; NEURONS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, WISTAR; RECEPTORS, GABA-B; SYNAPSES; TRANSCRIPTION FACTORS; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN;

EID: 84896261772     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.541987     Document Type: Article

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