A mouse model for Betacoronavirus subgroup 2c using a bat coronavirus strain HKU5 variant

mBio

Volumn 5, Issue 2, 2014, Pages

  Agnihothram, Sudhakar ^a   Yount Jr , Boyd L ^a   Donaldson, Eric F ^a   Huynh, Jeremy ^a   Menachery, Vineet D ^a   Gralinski, Lisa E ^a   Graham, Rachel L ^a   Becker, Michelle M ^b   Tomar, Sakshi ^d   Scobey, Trevor D ^a   Osswald, Heather L ^d   Whitmore, Alan ^a   Gopal, Robin ^c   Ghosh, Arun K ^d   Mesecar, Andrew ^d   Zambon, Maria ^c   Heise, Mark ^a   Denison, Mark R ^b   Baric, Ralph S ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS VACCINE;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAT CORONAVIRUS STRAIN HKU5; BETACORONAVIRUS SUBGROUP 2C; CONTROLLED STUDY; CORONAVIRUS; CORONAVIRUS INFECTION; EOSINOPHILIA; FLOW CYTOMETRY; GENE MUTATION; IMMUNOHISTOCHEMISTRY; LUNG ALVEOLUS EPITHELIUM; LUNG INFECTION; LUNG PARENCHYMA; M GENE; MOUSE; NONHUMAN; NSP13 GENE; NSP14 GENE; NUCLEOTIDE SEQUENCE; ORF5 GENE; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DOMAIN; SARS CORONAVIRUS; VIRUS GENE; VIRUS REPLICATION; VIRUS STRAIN; VIRUS VIRULENCE; WEIGHT REDUCTION;

ANIMALS; CHIROPTERA; CORONAVIRUS; CORONAVIRUS INFECTIONS; DISEASE MODELS, ANIMAL; DRUG CARRIERS; ENCEPHALITIS VIRUS, VENEZUELAN EQUINE; EOSINOPHILIA; GENETIC VECTORS; MICE; MICE, INBRED BALB C; RESPIRATORY SYSTEM; VACCINES, SYNTHETIC; VIRAL VACCINES;

EID: 84899747216     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00047-14     Document Type: Article

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