Acetaldehyde targets superoxide dismutase 2 in liver cancer cells inducing transient enzyme impairment and a rapid transcriptional recovery

Food and Chemical Toxicology

Volumn 69, Issue , 2014, Pages 102-108

  Clavijo Cornejo, Denise ^a   Gutiérrez Carrera, Mario ^a   Palestino Domínguez, Mayrel ^a   Dominguez Perez, Mayra ^a   Nuño, Natalia ^a   Souza, Veronica ^a,b   Miranda, Roxana U ^a   Kershenobich, David ^b,c   Gutiérrez Ruiz, Ma Concepción ^a,b   Bucio, Leticia ^a,b   Gómez Quiroz, Luis E ^a,b  

^a DEPARTAMENTO DE QUÍMICA   (Mexico)

^b Red Fisiopatología de las Enfermedades Hepáticas PROMEP SEP ^*  (Mexico)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

Acetaldehyde; Hepatocytes; Liver cancer; Nuclear factor kappa B; SOD

Indexed keywords

ACETALDEHYDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN KINASE C; COPPER ZINC SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ARTICLE; CANCER CELL CULTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REGULATION; ENZYME SYNTHESIS; HEPATOBLASTOMA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CANCER; OXIDATIVE STRESS; PROTEIN CONTENT; TRANSCRIPTION REGULATION; DRUG EFFECTS; METABOLISM; MITOCHONDRION; MOLECULARLY TARGETED THERAPY;

ACETALDEHYDE; HEP G2 CELLS; HUMANS; MITOCHONDRIA; MOLECULAR TARGETED THERAPY; NF-KAPPA B; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84899704433     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.04.002     Document Type: Article

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