-
1
-
-
20844444779
-
Idiosyncratic drug hepatotoxicity
-
Kaplowitz N. Idiosyncratic drug hepatotoxicity. Nat Rev Drug Discov 2005;4:489-499.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 489-499
-
-
Kaplowitz, N.1
-
2
-
-
85012828315
-
Risk factors for drug-induced liver disease
-
Kaplowitz N, DeLeve LD (eds.) New York: Informa Healthcare
-
DeLeve LD. Risk factors for drug-induced liver disease. In: Kaplowitz N, DeLeve LD (eds.) Drug-induced liver disease. New York: Informa Healthcare, 2007;291-305.
-
(2007)
Drug-induced Liver Disease
, pp. 291-305
-
-
DeLeve, L.D.1
-
3
-
-
0035110952
-
Mitochondria: Important target for drug toxicity?
-
Krähenbühl S. Mitochondria: important target for drug toxicity? J Hepatol 2001;34:334-336.
-
(2001)
J Hepatol
, vol.34
, pp. 334-336
-
-
Krähenbühl, S.1
-
4
-
-
0037339203
-
16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria
-
DOI 10.1097/00008571-200303000-00004
-
Sutton A, Khoury H, Prip-Buus C, Cepanec C, Pessayre D, Degoul F. The Ala16Val genetic dimorphism modulates the import of human manganese superoxide dismutase into rat liver mitochondria. Pharmacogenetics 2003;13:145-157. (Pubitemid 36324244)
-
(2003)
Pharmacogenetics
, vol.13
, Issue.3
, pp. 145-157
-
-
Sutton, A.1
Khoury, H.2
Prip-Buus, C.3
Cepanec, C.4
Pessayre, D.5
Degoul, F.6
-
5
-
-
34249284163
-
Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H:Quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury
-
Huang YS, Su WJ, Huang YH, Chen CY, Chang FY, Lin HC, et al. Genetic polymorphisms of manganese superoxide dismutase, NAD(P)H:quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to drug-induced liver injury. J Hepatol 2007;47:128-134.
-
(2007)
J Hepatol
, vol.47
, pp. 128-134
-
-
Huang, Y.S.1
Su, W.J.2
Huang, Y.H.3
Chen, C.Y.4
Chang, F.Y.5
Lin, H.C.6
-
6
-
-
0034489653
-
The glutathione peroxidases
-
Arthur JR. The glutathione peroxidases. Cell Mol Life Sci 2000;57:1825-1835.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 1825-1835
-
-
Arthur, J.R.1
-
7
-
-
4344649455
-
Functional variants in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients
-
DOI 10.2337/diabetes.53.9.2455
-
Hamanishi T, Furuta H, Kato H, Asako Doi1, Masanori Tamai1, Hiroko Shimomura, et al. Functional variant in the glutathione peroxidase-1 (GPx-1) gene are associated with increased intima-media thickness of carotid arteries and risk of macrovascular diseases in Japanese type 2 diabetic patients. Diabetes 2004;53:2455-2460. (Pubitemid 39145603)
-
(2004)
Diabetes
, vol.53
, Issue.9
, pp. 2455-2460
-
-
Hamanishi, T.1
Furuta, H.2
Kato, H.3
Doi, A.4
Tamai, M.5
Shimomura, H.6
Sakagashira, S.7
Nishi, M.8
Sasaki, H.9
Sanke, T.10
Nanjo, K.11
-
8
-
-
18744376412
-
Drug-induced liver injury: An analysis of 461 incidences submitted to the Spanish registry over a 10-year period
-
Andrade RJ, Lucena MI, Fernández MC, Pelaez G, Pachkoria K, García-Ruiz E, et al. Drug-induced liver injury: an analysis of 461 incidences submitted to the Spanish registry over a 10-year period. Gastroenterology 2005;129:512-521.
-
(2005)
Gastroenterology
, vol.129
, pp. 512-521
-
-
Andrade, R.J.1
Lucena, M.I.2
Fernández, M.C.3
Pelaez, G.4
Pachkoria, K.5
García-Ruiz, E.6
-
9
-
-
0025227871
-
Criteria of drug-induced liver disorders: Report of an international consensus meeting
-
Benichou C. Criteria of drug-induced liver disorders: report of an international consensus meeting. J Hepatol 1990;11:272-276.
-
(1990)
J Hepatol
, vol.11
, pp. 272-276
-
-
Benichou, C.1
-
11
-
-
19944399431
-
A comprehensive listing of bioactivation pathways of organic functional groups
-
DOI 10.2174/1389200054021799
-
Kalgutkar AS, Gardner I, Obach RS, Shaffer CL, Callegari E, Henne KR, et al. A comprehensive listing of bioactivation pathways of organic functional groups. Current Drug Metabolism 2005;6:161-225. (Pubitemid 40753853)
-
(2005)
Current Drug Metabolism
, vol.6
, Issue.3
, pp. 161-225
-
-
Kalgutkar, A.S.1
Gardner, I.2
Obach, R.S.3
Shaffer, C.L.4
Callegari, E.5
Henne, K.R.6
Mutlib, A.E.7
Dalvie, D.K.8
Lee, J.S.9
Nakai, Y.10
O'Donnell, J.P.11
Boer, J.12
Harriman, S.P.13
-
12
-
-
18844373318
-
Role of metabolism in drug-induced idiosyncratic hepatotoxicity
-
DOI 10.1080/10408440590935620
-
Walgren JL, Mitchell MD, Thompson DC. Role of metabolism in drug-induced idiosyncratic hepatotoxicity. Crit Rev Toxicol 2005;35:325-361. (Pubitemid 40691298)
-
(2005)
Critical Reviews in Toxicology
, vol.35
, Issue.4
, pp. 325-361
-
-
Walgren, J.L.1
Mitchell, M.D.2
Thompson, D.C.3
-
13
-
-
33947204690
-
Mitochondrial abnormalities: A link to idiosyncratic drug hepatotoxicity?
-
Boelsterli UA, Lim PLK. Mitochondrial abnormalities: a link to idiosyncratic drug hepatotoxicity? Toxicol Appl Pharmacol 2007;220:92-107.
-
(2007)
Toxicol Appl Pharmacol
, vol.220
, pp. 92-107
-
-
Boelsterli, U.A.1
Lim, P.L.K.2
-
14
-
-
0036163759
-
Mechanisms of hepatotoxicity
-
Jaeschke H, Gores GJ, Cederbaum AI, Hinson JA, Pessayre D, Lemasters JJ. Mechanisms of hepatotoxicity. Toxicol Sci 2002;65:166-176.
-
(2002)
Toxicol Sci
, vol.65
, pp. 166-176
-
-
Jaeschke, H.1
Gores, G.J.2
Cederbaum, A.I.3
Hinson, J.A.4
Pessayre, D.5
Lemasters, J.J.6
-
15
-
-
33947327550
-
Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to drug-induced idiosyncratic liver injury (DILI)
-
DOI 10.1038/sj.bjp.0707122, PII 0707122
-
Pachkoria K, Lucena MI, Ruiz-Cabello F, Crespo E, Cabello MR, Andrade RJ, et al. Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to drug-induced idiosyncratic liver injury (DILI). Br J Pharmacol 2007;150:808-815. (Pubitemid 46440210)
-
(2007)
British Journal of Pharmacology
, vol.150
, Issue.6
, pp. 808-815
-
-
Pachkoria, K.1
Lucena, M.I.2
Ruiz-Cabello, F.3
Crespo, E.4
Cabello, M.R.5
Andrade, R.J.6
-
16
-
-
0035513076
-
Candidate gene case-control association studies: Advantages and potential pitfalls
-
Daly AK, Day CP. Candidate gene case-control association studies: advantages and potential pitfalls. Br J Clin Pharmacol 2001;52:489-499.
-
(2001)
Br J Clin Pharmacol
, vol.52
, pp. 489-499
-
-
Daly, A.K.1
Day, C.P.2
-
17
-
-
49649102889
-
Glutathione S-transferase M1 and T1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury
-
Lucena MI, Andrade RJ, Martínez C, Ulzurrun E, García-Martín E, Borraz Y, et al. Glutathione S-transferase M1 and T1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury. HEPATOLOGY 2008;48:588-596.
-
(2008)
Hepatology
, vol.48
, pp. 588-596
-
-
Lucena, M.I.1
Andrade, R.J.2
Martínez, C.3
Ulzurrun, E.4
García-Martín, E.5
Borraz, Y.6
-
18
-
-
76749147800
-
Pharmacogenomics in drug induced liver injury
-
Andrade RJ, Agúndez JA, Lucena MI, Martínez C, Cueto R, García-Martín E. Pharmacogenomics in drug induced liver injury. Curr Drug Metab 2009;10:956-970.
-
(2009)
Curr Drug Metab
, vol.10
, pp. 956-970
-
-
Andrade, R.J.1
Agúndez, J.A.2
Lucena, M.I.3
Martínez, C.4
Cueto, R.5
García-Martín, E.6
-
19
-
-
34347250517
-
Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities
-
DOI 10.1093/toxsci/kfl180
-
Ong MMK, Latchoumycandane C, Boelsterli UA. Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities. Toxicol Sci 2007;97:205-213. (Pubitemid 47072169)
-
(2007)
Toxicological Sciences
, vol.97
, Issue.1
, pp. 205-213
-
-
Ong, M.M.K.1
Latchoumycandane, C.2
Boelsterli, U.A.3
-
20
-
-
67049169349
-
Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen
-
Fujimoto K, Kumagai K, Ito K, Arakawa S, Ando Y, Oda S, et al. Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen. Toxicol Pathol 2009;37:193-200.
-
(2009)
Toxicol Pathol
, vol.37
, pp. 193-200
-
-
Fujimoto, K.1
Kumagai, K.2
Ito, K.3
Arakawa, S.4
Ando, Y.5
Oda, S.6
-
21
-
-
18044364791
-
Mechanism of the tumor suppressive effect of MnSOD overexpression
-
Oberley LW. Mechanism of the tumor suppressive effect of MnSOD overexpression. Biomed Pharmacother 2005;59:143-148.
-
(2005)
Biomed Pharmacother
, vol.59
, pp. 143-148
-
-
Oberley, L.W.1
-
22
-
-
31744450413
-
Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase
-
DOI 10.1016/j.jtbi.2005.06.034, PII S0022519305002924
-
Kowald A, Lehrach H, Klipp E. Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase. J Theor Biol 2006;238:828-840. (Pubitemid 43175833)
-
(2006)
Journal of Theoretical Biology
, vol.238
, Issue.4
, pp. 828-840
-
-
Kowald, A.1
Lehrach, H.2
Klipp, E.3
-
23
-
-
0038708252
-
A study to survey susceptible genetic factors responsible for troglitazone-associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus
-
DOI 10.1016/S0009-9236(03)00014-6
-
Watanabe I, Tomita A, Shimizu M, Sugawara M, Yasumo H, Koishi R, et al. A study to survey susceptible genetic factors responsible for troglitazone- associated hepatotoxicity in Japanese patients with type 2 diabetes mellitus. Clin Pharmacol Ther 2003;73:435-455. (Pubitemid 36549828)
-
(2003)
Clinical Pharmacology and Therapeutics
, vol.73
, Issue.5
, pp. 435-455
-
-
Watanabe, I.1
Tomita, A.2
Shimizu, M.3
Sugawara, M.4
Yasumo, H.5
Koishi, R.6
Takahashi, T.7
Miyoshi, K.8
Nakamura, K.9
Izumi, T.10
Matsushita, Y.11
Furukawa, H.12
Haruyama, H.13
Koga, T.14
-
24
-
-
38949104743
-
Idiosyncratic drug reactions: Past, present, and future
-
DOI 10.1021/tx700186p
-
Uetrecht J. Idiosynctratic drug reactions: past, present and future. Chem Res Toxicol 2008:21:84-92. (Pubitemid 351219710)
-
(2008)
Chemical Research in Toxicology
, vol.21
, Issue.1
, pp. 84-92
-
-
Uetrecht, J.1
-
25
-
-
67349231918
-
Underlying mitochondrial dysfunction triggers flutamideinduced oxidative liver injury in a mouse model of idiosyncratic drug toxicity
-
Kashimshetty R, Desai VG, Kale VM, Lee T, Moland CL, Branham WS, et al. Underlying mitochondrial dysfunction triggers flutamideinduced oxidative liver injury in a mouse model of idiosyncratic drug toxicity. Toxicol Appl Pharmacol 2009;238:150-159.
-
(2009)
Toxicol Appl Pharmacol
, vol.238
, pp. 150-159
-
-
Kashimshetty, R.1
Desai, V.G.2
Kale, V.M.3
Lee, T.4
Moland, C.L.5
Branham, W.S.6
-
26
-
-
23244439961
-
Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids
-
DOI 10.1097/01.MPG.0000170600.80640.88
-
Sokol RJ, Dahl R, Devereaux MW, Yerushalmi B, Kobak GE, Gumpricht E. Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids. J Pediatr Gastroenterol Nutr 2005;41:235-243. (Pubitemid 41099374)
-
(2005)
Journal of Pediatric Gastroenterology and Nutrition
, vol.41
, Issue.2
, pp. 235-243
-
-
Sokol, R.J.1
Dahl, R.2
Devereaux, M.W.3
Yerushalmi, B.4
Kobak, G.E.5
Gumpricht, E.6
-
27
-
-
68949091980
-
Phenotypic characterization of idiosyncratic drug-induced liver injury: The influence of age and sex
-
Lucena MI, Andrade RJ, Kaplowitz N, García-Cortes M, Fernández MC, Romero-Gomez M, et al. Phenotypic characterization of idiosyncratic drug-induced liver injury: the influence of age and sex. HEPATOLOGY 2009;49:2001-2009.
-
(2009)
Hepatology
, vol.49
, pp. 2001-2009
-
-
Lucena, M.I.1
Andrade, R.J.2
Kaplowitz, N.3
García-Cortes, M.4
Fernández, M.C.5
Romero-Gomez, M.6
|