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Volumn 30, Issue 2, 2014, Pages 233-242

Cerebrospinal fluid biomarkers of Alzheimer's disease

Author keywords

Alzheimer's disease; biomarker; cerebrospinal fluid; proteomics; tau; amyloid

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; BETA SECRETASE 1; BIOLOGICAL MARKER; CHEMOKINE; COLONY STIMULATING FACTOR 1; DICKKOPF HOMOLOG 3; HAPTOGLOBIN; HEART TYPE FATTY ACID BINDING PROTEIN; ISOPROSTANE DERIVATIVE; KYOTORPHIN; LIPOPROTEIN RECEPTOR 11; NEURONAL PENTRAXIN RECEPTOR; PIGMENT EPITHELIUM DERIVED FACTOR; PROTEIN YKL 40; PSORIASIN; SPHINGOMYELIN; TAU PROTEIN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; VISININ LIKE PROTEIN 1;

EID: 84899694982     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-013-1412-1     Document Type: Review
Times cited : (14)

References (93)
  • 3
    • 0026024052 scopus 로고
    • On drawing impairment in Alzheimer's disease
    • Kirk A, Kertesz A. On drawing impairment in Alzheimer's disease. Arch Neurol 1991, 48: 73-77.
    • (1991) Arch Neurol , vol.48 , pp. 73-77
    • Kirk, A.1    Kertesz, A.2
  • 4
    • 0027474471 scopus 로고
    • Explicit memory in Alzheimer's, Huntington's, and Parkinson's diseases
    • Pillon B, Deweer B, Agid Y, Dubois B. Explicit memory in Alzheimer's, Huntington's, and Parkinson's diseases. Arch Neurol 1993, 50: 374-379. (Pubitemid 23105460)
    • (1993) Archives of Neurology , vol.50 , Issue.4 , pp. 374-379
    • Pillon, B.1    Deweer, B.2    Agid, Y.3    Dubois, B.4
  • 5
    • 0027312981 scopus 로고
    • Neuropsychological patterns and language deficits in 20 consecutive cases of autopsy-confirmed Alzheimer's disease
    • Price BH, Gurvit H, Weintraub S, Geula C, Leimkuhler E, Mesulam M. Neuropsychological patterns and language deficits in 20 consecutive cases of autopsy-confirmed Alzheimer's disease. Arch Neurol 1993, 50: 931-937. (Pubitemid 23275121)
    • (1993) Archives of Neurology , vol.50 , Issue.9 , pp. 931-937
    • Price, B.H.1    Gurvit, H.2    Weintraub, S.3    Geula, C.4    Leimkuhler, E.5    Mesulam, M.6
  • 6
    • 0033976206 scopus 로고    scopus 로고
    • Atypical and typical presentations of Alzheimer's disease: A clinical, neuropsychological, neuroimaging and pathological study of 13 cases
    • Galton CJ, Patterson K, Xuereb JH, Hodges JR. Atypical and typical presentations of Alzheimer's disease: a clinical, neuropsychological, neuroimaging and pathological study of 13 cases. Brain 2000, 123: 484-498. (Pubitemid 30099534)
    • (2000) Brain , vol.123 , Issue.3 , pp. 484-498
    • Galton, C.J.1    Patterson, K.2    Xuereb, J.H.3    Hodges, J.R.4
  • 8
    • 0029946212 scopus 로고    scopus 로고
    • Analysis of the episodic memory deficit in early Alzheimer's disease: Evidence from the doors and people test
    • DOI 10.1016/0028-3932(95)00151-4
    • Greene JD, Baddeley AD, Hodges JR. Analysis of the episodic memory deficit in early Alzheimer's disease: evidence from the doors and people test. Neuropsychologia 1996, 34: 537-551. (Pubitemid 26154491)
    • (1996) Neuropsychologia , vol.34 , Issue.6 , pp. 537-551
    • Greene, J.D.W.1    Baddeley, A.D.2    Hodges, J.R.3
  • 9
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297: 353-356. (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 10
    • 0029967367 scopus 로고    scopus 로고
    • Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis
    • DOI 10.1007/s004010050508
    • Braak H, Braak E. Development of Alzheimer-related neurofibrillary changes in the neocortex inversely recapitulates cortical myelogenesis. Acta Neuropathol 1996, 92: 197-201. (Pubitemid 26248463)
    • (1996) Acta Neuropathologica , vol.92 , Issue.2 , pp. 197-201
    • Braak, H.1    Braak, E.2
  • 12
    • 33750885775 scopus 로고    scopus 로고
    • Molecular and biochemical features in Alzheimer's disease
    • DOI 10.2174/138161206778792967
    • Pallas M, Camins A. Molecular and biochemical features in Alzheimer's disease. Curr Pharm Des 2006, 12: 4389-4408. (Pubitemid 44718296)
    • (2006) Current Pharmaceutical Design , vol.12 , Issue.33 , pp. 4389-4408
    • Pallas, M.1    Camins, A.2
  • 13
    • 0034594469 scopus 로고    scopus 로고
    • Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients
    • DOI 10.1016/S0197-4580(00)00090-7, PII S0197458000000907
    • Pappas BA, Bayley PJ, Bui BK, Hansen LA, Thal LJ. Choline acetyltransferase activity and cognitive domain scores of Alzheimer's patients. Neurobiol Aging 2000, 21: 11-17. (Pubitemid 30224780)
    • (2000) Neurobiology of Aging , vol.21 , Issue.1 , pp. 11-17
    • Pappas, B.A.1    Bayley, P.J.2    Bui, B.K.3    Hansen, L.A.4    Thal, L.J.5
  • 14
    • 0023881790 scopus 로고
    • Possible neurotransmitter basis of behavioral changes in Alzheimer's disease
    • Palmer AM, Stratmann GC, Procter AW, Bowen DM. Possible neurotransmitter basis of behavioral changes in Alzheimer's disease. Ann Neurol 1988, 23: 616-620.
    • (1988) Ann Neurol , vol.23 , pp. 616-620
    • Palmer, A.M.1    Stratmann, G.C.2    Procter, A.W.3    Bowen, D.M.4
  • 16
    • 79956266421 scopus 로고    scopus 로고
    • Proteomic technologies for the identification of disease biomarkers in serum: Advances and challenges ahead
    • Ray S, Reddy PJ, Jain R, Gollapalli K, Moiyadi A, Srivastava S. Proteomic technologies for the identification of disease biomarkers in serum: Advances and challenges ahead. Proteomics 2011, 11: 2139-2161.
    • (2011) Proteomics , vol.11 , pp. 2139-2161
    • Ray, S.1    Reddy, P.J.2    Jain, R.3    Gollapalli, K.4    Moiyadi, A.5    Srivastava, S.6
  • 17
    • 0032989712 scopus 로고    scopus 로고
    • Tangles and plaques in nondemented aging and 'preclinical' alzheimer's disease
    • DOI 10.1002/1531-8249(199903)45:3<358::AID-ANA12
    • Price JL, Morris JC. Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease. Ann Neurol 1999, 45: 358-368. (Pubitemid 29120041)
    • (1999) Annals of Neurology , vol.45 , Issue.3 , pp. 358-368
    • Price, J.L.1    Morris, J.C.2
  • 18
    • 70350061949 scopus 로고    scopus 로고
    • Multimodal techniques for diagnosis and prognosis of Alzheimer's disease
    • Perrin RJ, Fagan AM, Holtzman DM. Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature 2009, 461: 916-922.
    • (2009) Nature , vol.461 , pp. 916-922
    • Perrin, R.J.1    Fagan, A.M.2    Holtzman, D.M.3
  • 19
    • 79956125839 scopus 로고    scopus 로고
    • Biomarkers in Alzheimer's disease drug development
    • Cummings JL. Biomarkers in Alzheimer's disease drug development. Alzheimers Dement 2011, 7: e13-44.
    • (2011) Alzheimers Dement , vol.7
    • Cummings, J.L.1
  • 20
    • 25144513449 scopus 로고    scopus 로고
    • CSF biomarkers for Alzheimer's disease: Use in early diagnosis and evaluation of drug treatment
    • DOI 10.1586/14737159.5.5.661
    • Blennow K. CSF biomarkers for Alzheimer's disease: use in early diagnosis and evaluation of drug treatment. Expert Rev Mol Diagn 2005, 5: 661-672. (Pubitemid 41337462)
    • (2005) Expert Review of Molecular Diagnostics , vol.5 , Issue.5 , pp. 661-672
    • Blennow, K.1
  • 21
    • 0035997231 scopus 로고    scopus 로고
    • Biogenesis and metabolism of Alzheimer's disease Abeta amyloid peptides
    • DOI 10.1016/S0196-9781(02)00063-3, PII S0196978102000633
    • Evin G, Weidemann A. Biogenesis and metabolism of Alzheimer's disease Abeta amyloid peptides. Peptides 2002, 23: 1285-1297. (Pubitemid 34786707)
    • (2002) Peptides , vol.23 , Issue.7 , pp. 1285-1297
    • Evin, G.1    Weidemann, A.2
  • 22
    • 0026721943 scopus 로고
    • Beta-amyloid precursor protein cleavage by a membrane-bound protease
    • Sisodia SS. Beta-amyloid precursor protein cleavage by a membrane-bound protease. Proc Natl Acad Sci U S A 1992, 89: 6075-6079.
    • (1992) Proc Natl Acad Sci U S a , vol.89 , pp. 6075-6079
    • Sisodia, S.S.1
  • 23
    • 84864471159 scopus 로고    scopus 로고
    • A mutation in APP protects against Alzheimer/'s disease and age-related cognitive decline
    • Jonsson T, Atwal JK, Steinberg S, Snaedal J, Jonsson PV, Bjornsson S, et al. A mutation in APP protects against Alzheimer/'s disease and age-related cognitive decline. Nature 2012, 488(7409): 96-99
    • (2012) Nature , vol.488 , Issue.7409 , pp. 96-99
    • Jonsson, T.1    Atwal, J.K.2    Steinberg, S.3    Snaedal, J.4    Jonsson, P.V.5    Bjornsson, S.6
  • 24
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
    • DOI 10.1038/325733a0
    • Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, et al. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 1987, 325: 733-736. (Pubitemid 17054046)
    • (1987) Nature , vol.325 , Issue.6106 , pp. 733-736
    • Kang, J.1    Lemaire, H.-G.2    Unterbeck, A.3
  • 25
    • 33745027879 scopus 로고    scopus 로고
    • Molecular mechanisms for Alzheimer's disease: Implications for neuroimaging and therapeutics
    • DOI 10.1111/j.1471-4159.2006.03989.x
    • Masters CL, Cappai R, Barnham KJ, Villemagne VL. Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics. J Neurochem 2006, 97: 1700-1725. (Pubitemid 43873662)
    • (2006) Journal of Neurochemistry , vol.97 , Issue.6 , pp. 1700-1725
    • Masters, C.L.1    Cappai, R.2    Barnham, K.J.3    Villemagne, V.L.4
  • 26
    • 0032590054 scopus 로고    scopus 로고
    • Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
    • McLean CA, Cherny RA, Fraser FW, Fuller SJ, Smith MJ, Beyreuther K, et al. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann Neurol 1999, 46: 860-866.
    • (1999) Ann Neurol , vol.46 , pp. 860-866
    • McLean, C.A.1    Cherny, R.A.2    Fraser, F.W.3    Fuller, S.J.4    Smith, M.J.5    Beyreuther, K.6
  • 27
    • 0028169925 scopus 로고
    • Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: Evidence that an initially deposited species is A beta 42(43)
    • Iwatsubo T, Odaka A, Suzuki N, Mizusawa H, Nukina N, Ihara Y. Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). Neuron 1994, 13: 45-53.
    • (1994) Neuron , vol.13 , pp. 45-53
    • Iwatsubo, T.1    Odaka, A.2    Suzuki, N.3    Mizusawa, H.4    Nukina, N.5    Ihara, Y.6
  • 28
    • 84861914969 scopus 로고    scopus 로고
    • Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-beta1-42 oligomers are revealed in vivo by using a novel animal model
    • Brouillette J, Caillierez R, Zommer N, Alves-Pires C, Benilova I, Blum D, et al. Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-beta1-42 oligomers are revealed in vivo by using a novel animal model. J Neurosci 2012, 32: 7852-7861.
    • (2012) J Neurosci , vol.32 , pp. 7852-7861
    • Brouillette, J.1    Caillierez, R.2    Zommer, N.3    Alves-Pires, C.4    Benilova, I.5    Blum, D.6
  • 30
    • 0027332081 scopus 로고
    • beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: Implications for the pathology of Alzheimer disease
    • Roher AE, Lowenson JD, Clarke S, Woods AS, Cotter RJ, Gowing E, et al. beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. Proc Natl Acad Sci U S A 1993, 90: 10836-10840.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 10836-10840
    • Roher, A.E.1    Lowenson, J.D.2    Clarke, S.3    Woods, A.S.4    Cotter, R.J.5    Gowing, E.6
  • 31
    • 0028971443 scopus 로고
    • Amyloid beta-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation
    • Lannfelt L, Basun H, Vigo-Pelfrey C, Wahlund LO, Winblad B, Lieberburg I, et al. Amyloid beta-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation. Neurosci Lett 1995, 199: 203-206.
    • (1995) Neurosci Lett , vol.199 , pp. 203-206
    • Lannfelt, L.1    Basun, H.2    Vigo-Pelfrey, C.3    Wahlund, L.O.4    Winblad, B.5    Lieberburg, I.6
  • 33
    • 0028861225 scopus 로고
    • Concentrations of amyloid beta protein in cerebrospinal fluid of patients with Alzheimer's disease
    • van Gool WA, Kuiper MA, Walstra GJ, Wolters EC, Bolhuis PA. Concentrations of amyloid beta protein in cerebrospinal fluid of patients with Alzheimer's disease. Ann Neurol 1995, 37: 277-279.
    • (1995) Ann Neurol , vol.37 , pp. 277-279
    • Van Gool, W.A.1    Kuiper, M.A.2    Walstra, G.J.3    Wolters, E.C.4    Bolhuis, P.A.5
  • 34
    • 0033061647 scopus 로고    scopus 로고
    • Cerebrospinal fluid beta-amyloid((1-42)) in Alzheimer disease: Differences between early- and late-onset Alzheimer disease and stability during the course of disease
    • DOI 10.1001/archneur.56.6.673
    • Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, et al. Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: differences between early- and late-onset Alzheimer disease and stability during the course of disease. Arch Neurol 1999, 56: 673-680. (Pubitemid 29266465)
    • (1999) Archives of Neurology , vol.56 , Issue.6 , pp. 673-680
    • Andreasen, N.1    Hesse, C.2    Davidsson, P.3    Minthon, L.4    Wallin, A.5    Winblad, B.6    Vanderstichele, H.7    Vanmechelen, E.8    Blennow, K.9
  • 35
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • DOI 10.1016/S1474-4422(03)00530-1
    • Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol 2003, 2: 605-613. (Pubitemid 37162569)
    • (2003) Lancet Neurology , vol.2 , Issue.10 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 39
    • 33947223454 scopus 로고    scopus 로고
    • 42 ratio as a prediction of cognitive decline in nondemented older adults
    • DOI 10.1001/archneur.64.3.noc60123
    • Fagan AM, Roe CM, Xiong C, Mintun MA, Morris JC, Holtzman DM. Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol 2007, 64: 343-349. (Pubitemid 46425688)
    • (2007) Archives of Neurology , vol.64 , Issue.3 , pp. 343-349
    • Fagan, A.M.1    Roe, C.M.2    Xiong, C.3    Mintun, M.A.4    Morris, J.C.5    Holtzman, D.M.6
  • 44
    • 0034892016 scopus 로고    scopus 로고
    • Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: A discrimination from Alzheimer's disease?
    • DOI 10.1136/jnnp.71.3.401
    • Kapaki E, Kilidireas K, Paraskevas GP, Michalopoulou M, Patsouris E. Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: a discrimination from Alzheimer's disease? J Neurol Neurosurg Psychiatry 2001, 71: 401-403. (Pubitemid 32772543)
    • (2001) Journal of Neurology Neurosurgery and Psychiatry , vol.71 , Issue.3 , pp. 401-403
    • Kapaki, E.1    Kilidireas, K.2    Paraskevas, G.P.3    Michalopoulou, M.4    Patsouris, E.5
  • 46
  • 49
    • 0036182732 scopus 로고    scopus 로고
    • Decreased CSF-beta-amyloid 42 in Alzheimer's disease and amyotrophic lateral sclerosis may reflect mismetabolism of beta-amyloid induced by disparate mechanisms
    • Sjogren M, Davidsson P, Wallin A, Granerus AK, Grundstrom E, Askmark H, et al. Decreased CSF-beta-amyloid 42 in Alzheimer's disease and amyotrophic lateral sclerosis may reflect mismetabolism of beta-amyloid induced by disparate mechanisms. Dement Geriatr Cogn Disord 2002, 13: 112-118.
    • (2002) Dement Geriatr Cogn Disord , vol.13 , pp. 112-118
    • Sjogren, M.1    Davidsson, P.2    Wallin, A.3    Granerus, A.K.4    Grundstrom, E.5    Askmark, H.6
  • 50
    • 0034942145 scopus 로고    scopus 로고
    • Clinical significance of neurobiochemical profiles in the lumbar cerebrospinal fluid of Alzheimer's disease patients
    • DOI 10.1007/s007020170091
    • Rosler N, Wichart I, Jellinger KA. Clinical significance of neurobiochemical profiles in the lumbar cerebrospinal fluid of Alzheimer's disease patients. J Neural Transm 2001, 108: 231-246. (Pubitemid 32695765)
    • (2001) Journal of Neural Transmission , vol.108 , Issue.2 , pp. 231-246
    • Rosler, N.1    Wichart, I.2    Jellinger, K.A.3
  • 51
    • 0035997222 scopus 로고    scopus 로고
    • beta-Amyloid (Abeta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease
    • DOI 10.1016/S0196-9781(02)00056-6, PII S0196978102000566
    • Andreasen N, Blennow K. beta-amyloid (A beta) protein in cerebrospinal fluid as a biomarker for Alzheimer's disease. Peptides 2002, 23: 1205-1214. (Pubitemid 34786700)
    • (2002) Peptides , vol.23 , Issue.7 , pp. 1205-1214
    • Andreasen, N.1    Blennow, K.2
  • 53
    • 0036630457 scopus 로고    scopus 로고
    • Relationships among cerebrospinal fluid biomarkers in dementia of the Alzheimer type
    • DOI 10.1097/00002093-200207000-00003
    • Csernansky JG, Miller JP, McKeel D, Morris JC. Relationships among cerebrospinal fluid biomarkers in dementia of the Alzheimer type. Alzheimer Dis Assoc Disord 2002, 16: 144-149. (Pubitemid 35001089)
    • (2002) Alzheimer Disease and Associated Disorders , vol.16 , Issue.3 , pp. 144-149
    • Csernansky, J.G.1    Miller, J.P.2    McKeel, D.3    Morris, J.C.4
  • 54
    • 0037244487 scopus 로고    scopus 로고
    • Cerebrospinal fluid levels of total-tau, phosphotau and A beta 42 predicts development of Alzheimer's disease in patients with mild cognitive impairment
    • Andreasen N, Vanmechelen E, Vanderstichele H, Davidsson P, Blennow K. Cerebrospinal fluid levels of total-tau, phosphotau and A beta 42 predicts development of Alzheimer's disease in patients with mild cognitive impairment. Acta Neurol Scand Suppl 2003, 179: 47-51.
    • (2003) Acta Neurol Scand Suppl , vol.179 , pp. 47-51
    • Andreasen, N.1    Vanmechelen, E.2    Vanderstichele, H.3    Davidsson, P.4    Blennow, K.5
  • 57
    • 0032211829 scopus 로고    scopus 로고
    • Tau in Alzheimer's disease
    • DOI 10.1016/S0962-8924(98)01368-3, PII S0962892498013683
    • Mandelkow EM, Mandelkow E. Tau in Alzheimer's disease. Trends Cell Biol 1998, 8: 425-427. (Pubitemid 28529713)
    • (1998) Trends in Cell Biology , vol.8 , Issue.11 , pp. 425-427
    • Mandelkow, E.-M.1    Mandelkow, E.2
  • 59
    • 0036107977 scopus 로고    scopus 로고
    • Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients: An ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay
    • Hu YY, He SS, Wang X, Duan QH, Grundke-Iqbal I, Iqbal K, et al. Levels of nonphosphorylated and phosphorylated tau in cerebrospinal fluid of Alzheimer's disease patients : an ultrasensitive bienzyme-substrate-recycle enzyme-linked immunosorbent assay. Am J Pathol 2002, 160: 1269-1278. (Pubitemid 34411631)
    • (2002) American Journal of Pathology , vol.160 , Issue.4 , pp. 1269-1278
    • Hu, Y.Y.1    He, S.S.2    Wang, X.3    Duan, Q.H.4    Grundke-Iqbal, I.5    Iqbal, K.6    Wang, J.7
  • 60
    • 67651204382 scopus 로고    scopus 로고
    • CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment
    • Mattsson N, Zetterberg H, Hansson O, Andreasen N, Parnetti L, Jonsson M, et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. JAMA 2009, 302: 385-393.
    • (2009) JAMA , vol.302 , pp. 385-393
    • Mattsson, N.1    Zetterberg, H.2    Hansson, O.3    Andreasen, N.4    Parnetti, L.5    Jonsson, M.6
  • 62
    • 62349094208 scopus 로고    scopus 로고
    • Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment
    • Brys M, Pirraglia E, Rich K, Rolstad S, Mosconi L, Switalski R, et al. Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment. Neurobiol Aging 2009, 30: 682-690.
    • (2009) Neurobiol Aging , vol.30 , pp. 682-690
    • Brys, M.1    Pirraglia, E.2    Rich, K.3    Rolstad, S.4    Mosconi, L.5    Switalski, R.6
  • 66
    • 0037040525 scopus 로고    scopus 로고
    • Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients
    • DOI 10.1016/S0304-3940(02)00047-2, PII S0304394002000472
    • Hu YY, He SS, Wang XC, Duan QH, Khatoon S, Iqbal K, et al. Elevated levels of phosphorylated neurofilament proteins in cerebrospinal fluid of Alzheimer disease patients. Neurosci Lett 2002, 320: 156-160. (Pubitemid 34164438)
    • (2002) Neuroscience Letters , vol.320 , Issue.3 , pp. 156-160
    • Hu, Y.-Y.1    He, S.-S.2    Wang, X.-C.3    Duan, Q.-H.4    Khatoon, S.5    Iqbal, K.6    Grundke-Iqbal, I.7    Wang, J.-Z.8
  • 68
    • 75749143930 scopus 로고    scopus 로고
    • Amyloid-beta(1-42), total tau, and phosphorylated tau as cerebrospinal fluid biomarkers for the diagnosis of Alzheimer disease
    • Mulder C, Verwey NA, van der Flier WM, Bouwman FH, Kok A, van Elk EJ, et al. Amyloid-beta(1-42), total tau, and phosphorylated tau as cerebrospinal fluid biomarkers for the diagnosis of Alzheimer disease. Clin Chem 2010, 56: 248-253.
    • (2010) Clin Chem , vol.56 , pp. 248-253
    • Mulder, C.1    Verwey, N.A.2    Van Der Flier, W.M.3    Bouwman, F.H.4    Kok, A.5    Van Elk, E.J.6
  • 69
    • 58449133739 scopus 로고    scopus 로고
    • S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10
    • Qin W, Ho L, Wang J, Peskind E, Pasinetti GM. S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. PLoS One 2009, 4: e4183
    • (2009) PLoS One , vol.4
    • Qin, W.1    Ho, L.2    Wang, J.3    Peskind, E.4    Pasinetti, G.M.5
  • 72
    • 78651269012 scopus 로고    scopus 로고
    • A beta 40 Oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease
    • Gao CM, Yam AY, Wang XM, Magdangal E, Salisbury C, Peretz D, et al. A beta 40 Oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease. PLoS One 2010, 5.
    • (2010) PLoS One , vol.5
    • Gao, C.M.1    Yam, A.Y.2    Wang, X.M.3    Magdangal, E.4    Salisbury, C.5    Peretz, D.6
  • 74
    • 84863423724 scopus 로고    scopus 로고
    • Cerebrospinal fluid amyloid-beta 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia
    • Bibl M, Gallus M, Welge V, Esselmann H, Wolf S, Ruther E, et al. Cerebrospinal fluid amyloid-beta 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia. J Neural Transm 2012, 119: 805-813.
    • (2012) J Neural Transm , vol.119 , pp. 805-813
    • Bibl, M.1    Gallus, M.2    Welge, V.3    Esselmann, H.4    Wolf, S.5    Ruther, E.6
  • 76
    • 78549247122 scopus 로고    scopus 로고
    • Macrophage colony-stimulating factor (M-CSF) in plasma and CSF of patients with mild cognitive impairment and Alzheimer's disease
    • Laske C, Stransky E, Hoffmann N, Maetzler W, Straten G, Eschweiler GW, et al. Macrophage colony-stimulating factor (M-CSF) in plasma and CSF of patients with mild cognitive impairment and Alzheimer's disease. Curr Alzheimer Res 2010, 7: 409-414.
    • (2010) Curr Alzheimer Res , vol.7 , pp. 409-414
    • Laske, C.1    Stransky, E.2    Hoffmann, N.3    Maetzler, W.4    Straten, G.5    Eschweiler, G.W.6
  • 77
    • 80053484102 scopus 로고    scopus 로고
    • Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease
    • Jiang H, Hampel H, Prvulovic D, Wallin A, Blennow K, Li RN, et al. Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease. Mol Neurodegener 2011, 6: 69.
    • (2011) Mol Neurodegener , vol.6 , pp. 69
    • Jiang, H.1    Hampel, H.2    Prvulovic, D.3    Wallin, A.4    Blennow, K.5    Li, R.N.6
  • 78
    • 62949121626 scopus 로고    scopus 로고
    • Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases
    • Yin GN, Lee HW, Cho JY, Suk K. Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases. Brain Res 2009, 1265: 158-170.
    • (2009) Brain Res , vol.1265 , pp. 158-170
    • Yin, G.N.1    Lee, H.W.2    Cho, J.Y.3    Suk, K.4
  • 79
    • 84888202286 scopus 로고    scopus 로고
    • CSF alpha-synuclein improves diagnostic and prognostic performance of CSF tau and A beta in Alzheimer's disease
    • Toledo JB, Korff A, Shaw LM, Trojanowski JQ, Zhang J. CSF alpha-synuclein improves diagnostic and prognostic performance of CSF tau and A beta in Alzheimer's disease. Acta Neuropathol 2013, 126: 683-697.
    • (2013) Acta Neuropathol , vol.126 , pp. 683-697
    • Toledo, J.B.1    Korff, A.2    Shaw, L.M.3    Trojanowski, J.Q.4    Zhang, J.5
  • 80
    • 84895829915 scopus 로고    scopus 로고
    • Neuropeptide kyotorphin (tyrosyl-arginine) has decreased levels in the cerebro-spinal fluid of Alzheimer's disease patients: Potential diagnostic and pharmacologic alimplications
    • Santos SM, Garcia-Nimo L, Santos SS, Tavares I, Cocho JA, Castanho M. Neuropeptide kyotorphin (tyrosyl-arginine) has decreased levels in the cerebro-spinal fluid of Alzheimer's disease patients: potential diagnostic and pharmacologic alimplications. Front Aging Neurosci 2013, 5.
    • (2013) Front Aging Neurosci , vol.5
    • Santos, S.M.1    Garcia-Nimo, L.2    Santos, S.S.3    Tavares, I.4    Cocho, J.A.5    Castanho, M.6
  • 81
    • 79952701623 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid F-2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers
    • Montine TJ, Peskind ER, Quinn JF, Wilson AM, Montine KS, Galasko D. Increased cerebrospinal fluid F-2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers. Neuromolecular Med 2011, 13: 37-43.
    • (2011) Neuromolecular Med , vol.13 , pp. 37-43
    • Montine, T.J.1    Peskind, E.R.2    Quinn, J.F.3    Wilson, A.M.4    Montine, K.S.5    Galasko, D.6
  • 84
    • 80051481026 scopus 로고    scopus 로고
    • Visinin-like Protein-1: Diagnostic and prognostic biomarker in Alzheimer disease
    • Tarawneh R, D'Angelo G, Macy E, Xiong CJ, Carter D, Cairns NJ, et al. Visinin-like Protein-1: diagnostic and prognostic biomarker in Alzheimer disease. Ann Neurol 2011, 70: 274-285.
    • (2011) Ann Neurol , vol.70 , pp. 274-285
    • Tarawneh, R.1    D'Angelo, G.2    Macy, E.3    Xiong, C.J.4    Carter, D.5    Cairns, N.J.6
  • 85
    • 84860832253 scopus 로고    scopus 로고
    • CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease
    • Tarawneh R, Lee JM, Ladenson JH, Morris JC, Holtzman DM. CSF VILIP-1 predicts rates of cognitive decline in early Alzheimer disease. Neurology 2012, 78: 709-719.
    • (2012) Neurology , vol.78 , pp. 709-719
    • Tarawneh, R.1    Lee, J.M.2    Ladenson, J.H.3    Morris, J.C.4    Holtzman, D.M.5
  • 86
  • 87
    • 78650171191 scopus 로고    scopus 로고
    • Nano-HPLC-MS analysis of phospholipids in cerebrospinal fluid of Alzheimer's disease patients - A pilot study
    • Kosicek M, Kirsch S, Bene R, Trkanjec Z, Titlic M, Bindila L, et al. Nano-HPLC-MS analysis of phospholipids in cerebrospinal fluid of Alzheimer's disease patients-a pilot study. Anal Bioanal Chem 2010, 398: 2929-2937.
    • (2010) Anal Bioanal Chem , vol.398 , pp. 2929-2937
    • Kosicek, M.1    Kirsch, S.2    Bene, R.3    Trkanjec, Z.4    Titlic, M.5    Bindila, L.6
  • 88
    • 79951938156 scopus 로고    scopus 로고
    • Combined measurement of PEDF, haptoglobin and tau in cerebrospinal fluid improves the diagnostic discrimination between alzheimer's disease and other dementias
    • Abraham JD, Calvayrac-Pawlowski S, Cobo S, Salvetat N, Vicat G, Molina L, et al. Combined measurement of PEDF, haptoglobin and tau in cerebrospinal fluid improves the diagnostic discrimination between alzheimer's disease and other dementias. Biomarkers 2011, 16: 161-171.
    • (2011) Biomarkers , vol.16 , pp. 161-171
    • Abraham, J.D.1    Calvayrac-Pawlowski, S.2    Cobo, S.3    Salvetat, N.4    Vicat, G.5    Molina, L.6
  • 89
    • 84885182452 scopus 로고    scopus 로고
    • Heart-type fatty acid binding protein and vascular endothelial growth factor: Cerebrospinal fluid biomarker candidates for Alzheimer's disease
    • Guo LH, Alexopoulos P, Perneczky R. Heart-type fatty acid binding protein and vascular endothelial growth factor: cerebrospinal fluid biomarker candidates for Alzheimer's disease. Eur Arch Psychiatry Clin Neurosci 2013, 263: 553-560.
    • (2013) Eur Arch Psychiatry Clin Neurosci , vol.263 , pp. 553-560
    • Guo, L.H.1    Alexopoulos, P.2    Perneczky, R.3
  • 90
    • 84863229780 scopus 로고    scopus 로고
    • Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid
    • Vafadar-Isfahani B, Ball G, Coveney C, Lemetre C, Boocock D, Minthon L, et al. Identification of SPARC-like 1 protein as part of a biomarker panel for Alzheimer's disease in cerebrospinal fluid. J Alzheimers Dis 2012, 28: 625-636.
    • (2012) J Alzheimers Dis , vol.28 , pp. 625-636
    • Vafadar-Isfahani, B.1    Ball, G.2    Coveney, C.3    Lemetre, C.4    Boocock, D.5    Minthon, L.6
  • 91
    • 79955506338 scopus 로고    scopus 로고
    • Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease
    • Perrin RJ, Craig-Schapiro R, Malone JP, Shah AR, Gilmore P, Davis AE, et al. Identification and validation of novel cerebrospinal fluid biomarkers for staging early Alzheimer's disease. PLoS One 2011, 6: e16032.
    • (2011) PLoS One , vol.6
    • Perrin, R.J.1    Craig-Schapiro, R.2    Malone, J.P.3    Shah, A.R.4    Gilmore, P.5    Davis, A.E.6
  • 92
    • 79955431733 scopus 로고    scopus 로고
    • Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis
    • Craig-Schapiro R, Kuhn M, Xiong CJ, Pickering EH, Liu JX, Misko TP, et al. Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis. PLoS One 2011, 6: e18850.
    • (2011) PLoS One , vol.6
    • Craig-Schapiro, R.1    Kuhn, M.2    Xiong, C.J.3    Pickering, E.H.4    Liu, J.X.5    Misko, T.P.6
  • 93
    • 80055039372 scopus 로고    scopus 로고
    • Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: Identification and prospective evaluation of new synaptic biomarkers
    • Jahn H, Wittke S, Zurbig P, Raedler TJ, Arlt S, Kellmann M, et al. Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers. PLoS One 2011, 6: e26540.
    • (2011) PLoS One , vol.6
    • Jahn, H.1    Wittke, S.2    Zurbig, P.3    Raedler, T.J.4    Arlt, S.5    Kellmann, M.6


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