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Volumn 6, Issue 4, 2011, Pages

Multiplexed immunoassay panel identifies novel CSF biomarkers for alzheimer's disease diagnosis and prognosis

Author keywords

[No Author keywords available]

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; AMYLOID BETA PROTEIN[1-42]; BIOLOGICAL MARKER; CALBINDIN; CYSTATIN C; EOTAXIN 3; FATTY ACID SYNTHASE; FIBRINOGEN; GROWTH REGULATED ALPHA PROTEIN; MACROPHAGE MIGRATION INHIBITION FACTOR; PANCREAS POLYPEPTIDE; PLASMINOGEN ACTIVATOR INHIBITOR 1; STROMELYSIN 2; TAU PROTEIN; TAU PROTEIN 181; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND RECEPTOR 3; UNCLASSIFIED DRUG; VASCULOTROPIN;

EID: 79955431733     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0018850     Document Type: Article
Times cited : (197)

References (95)
  • 4
    • 70350061949 scopus 로고    scopus 로고
    • Multimodal techniques for diagnosis and prognosis of Alzheimer's disease
    • Perrin RJ, Fagan AM, Holtzman DM, (2009) Multimodal techniques for diagnosis and prognosis of Alzheimer's disease. Nature 461: 916-922.
    • (2009) Nature , vol.461 , pp. 916-922
    • Perrin, R.J.1    Fagan, A.M.2    Holtzman, D.M.3
  • 5
    • 0141738373 scopus 로고    scopus 로고
    • CSF Markers for Incipient Alzheimer's Disease
    • Blennow K, Hampel H, (2003) CSF Markers for Incipient Alzheimer's Disease. Lancet Neurol 2: 605-613.
    • (2003) Lancet Neurol , vol.2 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 6
    • 33644832047 scopus 로고    scopus 로고
    • Inverse relation between in vivo amyloid imaging load and CSF Aβ42 in humans
    • Fagan A, Mintun M, Mach R, Lee S-Y, Dence C, Shah A, et al. (2006) Inverse relation between in vivo amyloid imaging load and CSF Aβ42 in humans. Ann Neurol 59: 512-519.
    • (2006) Ann Neurol , vol.59 , pp. 512-519
    • Fagan, A.1    Mintun, M.2    Mach, R.3    Lee, S.-Y.4    Dence, C.5    Shah, A.6
  • 7
    • 33947223454 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau/Aβ42 ratio as a prediction of cognitive decline in nondemented older adults
    • Fagan A, Roe C, Xiong C, Mintun M, Morris J, Holtzman D, (2007) Cerebrospinal fluid tau/Aβ42 ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol 64: 343-349.
    • (2007) Arch Neurol , vol.64 , pp. 343-349
    • Fagan, A.1    Roe, C.2    Xiong, C.3    Mintun, M.4    Morris, J.5    Holtzman, D.6
  • 8
    • 77949425172 scopus 로고    scopus 로고
    • Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease
    • Fagan AM, Mintun MA, Shah AR, Aldea P, Roe CM, Mach RH, et al. (2009) Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: implications for future clinical trials of Alzheimer's disease. EMBO Mol Med 1: 371-380.
    • (2009) EMBO Mol Med , vol.1 , pp. 371-380
    • Fagan, A.M.1    Mintun, M.A.2    Shah, A.R.3    Aldea, P.4    Roe, C.M.5    Mach, R.H.6
  • 10
    • 0033061647 scopus 로고    scopus 로고
    • Cerebrospinal fluid β-amyloid(1-42) in Alzheimer's disease: Differences between early- and late-onset Alzheimer's disease and stability during the course of disease
    • Andreasen N, Hess C, Davidsson P, Minthon L, Wallin A, Winblad B, et al. (1999) Cerebrospinal fluid β-amyloid(1-42) in Alzheimer's disease: Differences between early- and late-onset Alzheimer's disease and stability during the course of disease. Arch Neurol 56: 673-680.
    • (1999) Arch Neurol , vol.56 , pp. 673-680
    • Andreasen, N.1    Hess, C.2    Davidsson, P.3    Minthon, L.4    Wallin, A.5    Winblad, B.6
  • 14
    • 32544435900 scopus 로고    scopus 로고
    • Association Between CSF Biomarkers and Incipient Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Follow-Up Study
    • Hansson O, Zetterberg H, Buchhave P, Londos E, Blennow K, Minthon L, (2006) Association Between CSF Biomarkers and Incipient Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Follow-Up Study. Lancent Neurology 5: 228-234.
    • (2006) Lancent Neurology , vol.5 , pp. 228-234
    • Hansson, O.1    Zetterberg, H.2    Buchhave, P.3    Londos, E.4    Blennow, K.5    Minthon, L.6
  • 15
    • 34547890294 scopus 로고    scopus 로고
    • CSF tau/Aβ42 ratio for increased risk of mild cognitive impairment: A follow-up study
    • Li G, Sokal I, Quinn J, Leverenz J, Brodey M, Schellenberg G, et al. (2007) CSF tau/Aβ42 ratio for increased risk of mild cognitive impairment: A follow-up study. Neurology 69: 631-639.
    • (2007) Neurology , vol.69 , pp. 631-639
    • Li, G.1    Sokal, I.2    Quinn, J.3    Leverenz, J.4    Brodey, M.5    Schellenberg, G.6
  • 16
    • 0037514257 scopus 로고    scopus 로고
    • Decreased β-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer's disease
    • Sunderland T, Linker G, Mirza N, Putnam K, Friedman D, Kimmel L, et al. (2003) Decreased β-amyloid1-42 and increased tau levels in cerebrospinal fluid of patients with Alzheimer's disease. JAMA 289: 2094-2103.
    • (2003) JAMA , vol.289 , pp. 2094-2103
    • Sunderland, T.1    Linker, G.2    Mirza, N.3    Putnam, K.4    Friedman, D.5    Kimmel, L.6
  • 17
    • 20944443414 scopus 로고    scopus 로고
    • Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease
    • discussion 173-180
    • Zhang J, Goodlett DR, Quinn JF, Peskind E, Kaye JA, Zhou Y, et al. (2005) Quantitative proteomics of cerebrospinal fluid from patients with Alzheimer disease. J Alzheimers Dis 7: 125-133; discussion 173-180.
    • (2005) J Alzheimers Dis , vol.7 , pp. 125-133
    • Zhang, J.1    Goodlett, D.R.2    Quinn, J.F.3    Peskind, E.4    Kaye, J.A.5    Zhou, Y.6
  • 19
    • 33947287762 scopus 로고    scopus 로고
    • Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment
    • Simonsen A, McGuire J, Hansson O, Zetterberg H, Podust V, Davies H, et al. (2007) Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment. Arch Neurol 64: 366-370.
    • (2007) Arch Neurol , vol.64 , pp. 366-370
    • Simonsen, A.1    McGuire, J.2    Hansson, O.3    Zetterberg, H.4    Podust, V.5    Davies, H.6
  • 20
    • 36448997798 scopus 로고    scopus 로고
    • A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia
    • Simonsen AH, McGuire J, Podust VN, Hagnelius NO, Nilsson TK, Kapaki E, et al. (2007) A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia. Dement Geriatr Cogn Disord 24: 434-440.
    • (2007) Dement Geriatr Cogn Disord , vol.24 , pp. 434-440
    • Simonsen, A.H.1    McGuire, J.2    Podust, V.N.3    Hagnelius, N.O.4    Nilsson, T.K.5    Kapaki, E.6
  • 21
    • 0041358773 scopus 로고    scopus 로고
    • A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease
    • Carrette O, Demalte I, Scherl A, Yalkinoglu O, Corthals G, Burkhard P, et al. (2003) A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease. Proteomics 3: 1486-1494.
    • (2003) Proteomics , vol.3 , pp. 1486-1494
    • Carrette, O.1    Demalte, I.2    Scherl, A.3    Yalkinoglu, O.4    Corthals, G.5    Burkhard, P.6
  • 23
    • 33747409456 scopus 로고    scopus 로고
    • Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders
    • Abdi F, Quinn J, Jankovic J, McIntosh M, Leverenz J, Peskind E, et al. (2006) Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis 9: 293-348.
    • (2006) J Alzheimers Dis , vol.9 , pp. 293-348
    • Abdi, F.1    Quinn, J.2    Jankovic, J.3    McIntosh, M.4    Leverenz, J.5    Peskind, E.6
  • 24
    • 33847665648 scopus 로고    scopus 로고
    • Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease
    • Finehout EJ, Franck Z, Choe LH, Relkin N, Lee KH, (2007) Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease. Ann Neurol 61: 120-129.
    • (2007) Ann Neurol , vol.61 , pp. 120-129
    • Finehout, E.J.1    Franck, Z.2    Choe, L.H.3    Relkin, N.4    Lee, K.H.5
  • 26
    • 38449092906 scopus 로고    scopus 로고
    • Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease
    • Hu Y, Hosseini A, Kauwe J, Gross J, Cairns N, Goate A, et al. (2007) Identification and validation of novel CSF biomarkers for early stages of Alzheimer's disease. Proteomics- Clin Appl 1: 1373-1384.
    • (2007) Proteomics - Clin Appl , vol.1 , pp. 1373-1384
    • Hu, Y.1    Hosseini, A.2    Kauwe, J.3    Gross, J.4    Cairns, N.5    Goate, A.6
  • 27
    • 0021271971 scopus 로고
    • Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease
    • McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan E, (1984) Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34: 939-944.
    • (1984) Neurology , vol.34 , pp. 939-944
    • McKhann, G.1    Drachman, D.2    Folstein, M.3    Katzman, R.4    Price, D.5    Stadlan, E.6
  • 28
    • 0027425211 scopus 로고
    • The Clinical Dementia Rating (CDR). Current version and scoring rules
    • Morris JC, (1993) The Clinical Dementia Rating (CDR). Current version and scoring rules. Neurology 43: 2412-2414.
    • (1993) Neurology , vol.43 , pp. 2412-2414
    • Morris, J.C.1
  • 29
    • 33747054765 scopus 로고    scopus 로고
    • Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI
    • Storandt M, Grant E, Miller J, Morris J, (2006) Longitudinal course and neuropathologic outcomes in original vs revised MCI and in pre-MCI. Neurology 67: 467-473.
    • (2006) Neurology , vol.67 , pp. 467-473
    • Storandt, M.1    Grant, E.2    Miller, J.3    Morris, J.4
  • 32
    • 10744232413 scopus 로고    scopus 로고
    • Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
    • Klunk W, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt D, et al. (2004) Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann Neurol 55: 306-319.
    • (2004) Ann Neurol , vol.55 , pp. 306-319
    • Klunk, W.1    Engler, H.2    Nordberg, A.3    Wang, Y.4    Blomqvist, G.5    Holt, D.6
  • 33
    • 79951480123 scopus 로고    scopus 로고
    • R: A language and environment for statistical computing
    • Team RDC, R Foundation for Statistical Computing
    • Team RDC (2010) R: A language and environment for statistical computing. R Foundation for Statistical Computing.
    • (2010)
  • 34
    • 8744249121 scopus 로고    scopus 로고
    • Combining correlated diagnostic tests---application to neuropathologic diagnosis of Alzheimer's disease
    • Xiong C, McKeel D, Miller J, Morris J, (2004) Combining correlated diagnostic tests---application to neuropathologic diagnosis of Alzheimer's disease. Medical Decision Making 24: 659-669.
    • (2004) Medical Decision Making , vol.24 , pp. 659-669
    • Xiong, C.1    McKeel, D.2    Miller, J.3    Morris, J.4
  • 37
    • 0035478854 scopus 로고    scopus 로고
    • Random Forests
    • Breiman L, (2001) Random Forests. Mach Learn 45: 5-32.
    • (2001) Mach Learn , vol.45 , pp. 5-32
    • Breiman, L.1
  • 38
    • 0035470889 scopus 로고    scopus 로고
    • Greedy Function Approximation: A Gradient Boosting Machine
    • Friedman JH, (2001) Greedy Function Approximation: A Gradient Boosting Machine. The Annals of Statistics 29: 1189-1232.
    • (2001) The Annals of Statistics , vol.29 , pp. 1189-1232
    • Friedman, J.H.1
  • 40
    • 79955431253 scopus 로고    scopus 로고
    • Proceedings of Neural Information Processing Systems Workshop on Statistical methods for Computational Experiments In Visual Processing and Computer Vision. Whistler
    • Caputo B, Sim K, Furesjo F, Smola A, (2001) Appearance-based object recognition using SVMs: which kernel should I use? Proceedings of Neural Information Processing Systems Workshop on Statistical methods for Computational Experiments In Visual Processing and Computer Vision. Whistler.
    • (2001) Appearance-based object recognition using SVMs: Which kernel should I use?
    • Caputo, B.1    Sim, K.2    Furesjo, F.3    Smola, A.4
  • 41
    • 2342533421 scopus 로고    scopus 로고
    • Class Prediction by Nearest Shrunken Centroids, with Applications to DNA Microarrays
    • Tibshirani R, Hastie T, Narasimhan B, Chu G, (2003) Class Prediction by Nearest Shrunken Centroids, with Applications to DNA Microarrays. Statistical Science 18: 104-117.
    • (2003) Statistical Science , vol.18 , pp. 104-117
    • Tibshirani, R.1    Hastie, T.2    Narasimhan, B.3    Chu, G.4
  • 42
    • 0003684449 scopus 로고    scopus 로고
    • The Elements of Statistical Learning
    • New York, Springer-Verlag
    • Hastie T, Tibshirani R, Friedman JH, (2001) The Elements of Statistical Learning. New York Springer-Verlag.
    • (2001)
    • Hastie, T.1    Tibshirani, R.2    Friedman, J.H.3
  • 44
    • 70350225480 scopus 로고    scopus 로고
    • Increased plasma urotensin-II and carotid atherosclerosis are associated with vascular dementia
    • Ban Y, Watanabe T, Suguro T, Matsuyama TA, Iso Y, Sakai T, et al. (2009) Increased plasma urotensin-II and carotid atherosclerosis are associated with vascular dementia. J Atheroscler Thromb 16: 179-187.
    • (2009) J Atheroscler Thromb , vol.16 , pp. 179-187
    • Ban, Y.1    Watanabe, T.2    Suguro, T.3    Matsuyama, T.A.4    Iso, Y.5    Sakai, T.6
  • 45
    • 77649131948 scopus 로고    scopus 로고
    • The role of macrophage migration inhibitory factor in Alzheimer's disease
    • Bacher M, Deuster O, Aljabari B, Egensperger R, Neff F, Jessen F, et al. (2010) The role of macrophage migration inhibitory factor in Alzheimer's disease. Mol Med 16: 116-121.
    • (2010) Mol Med , vol.16 , pp. 116-121
    • Bacher, M.1    Deuster, O.2    Aljabari, B.3    Egensperger, R.4    Neff, F.5    Jessen, F.6
  • 46
    • 64249099065 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer's disease
    • Popp J, Bacher M, Kolsch H, Noelker C, Deuster O, Dodel R, et al. (2009) Macrophage migration inhibitory factor in mild cognitive impairment and Alzheimer's disease. J Psychiatr Res 43: 749-753.
    • (2009) J Psychiatr Res , vol.43 , pp. 749-753
    • Popp, J.1    Bacher, M.2    Kolsch, H.3    Noelker, C.4    Deuster, O.5    Dodel, R.6
  • 47
    • 34347407998 scopus 로고    scopus 로고
    • Fibrinogen gamma-A chain precursor in CSF: a candidate biomarker for Alzheimer's disease
    • Lee JW, Namkoong H, Kim HK, Kim S, Hwang DW, Na HR, et al. (2007) Fibrinogen gamma-A chain precursor in CSF: a candidate biomarker for Alzheimer's disease. BMC Neurol 7: 14.
    • (2007) BMC Neurol , vol.7 , pp. 14
    • Lee, J.W.1    Namkoong, H.2    Kim, H.K.3    Kim, S.4    Hwang, D.W.5    Na, H.R.6
  • 49
    • 33644663637 scopus 로고    scopus 로고
    • Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia
    • van Oijen M, Witteman JC, Hofman A, Koudstaal PJ, Breteler MM, (2005) Fibrinogen is associated with an increased risk of Alzheimer disease and vascular dementia. Stroke 36: 2637-2641.
    • (2005) Stroke , vol.36 , pp. 2637-2641
    • van Oijen, M.1    Witteman, J.C.2    Hofman, A.3    Koudstaal, P.J.4    Breteler, M.M.5
  • 50
    • 0035132281 scopus 로고    scopus 로고
    • Local and systemic GM-CSF increase in Alzheimer's disease and vascular dementia
    • Tarkowski E, Wallin A, Regland B, Blennow K, Tarkowski A, (2001) Local and systemic GM-CSF increase in Alzheimer's disease and vascular dementia. Acta Neurol Scand 103: 166-174.
    • (2001) Acta Neurol Scand , vol.103 , pp. 166-174
    • Tarkowski, E.1    Wallin, A.2    Regland, B.3    Blennow, K.4    Tarkowski, A.5
  • 51
    • 0343569927 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid fas (Apo-1) levels in Alzheimer's disease. Relationship with IL-6 concentrations
    • Martinez M, Fernandez-Vivancos E, Frank A, De la Fuente M, Hernanz A, (2000) Increased cerebrospinal fluid fas (Apo-1) levels in Alzheimer's disease. Relationship with IL-6 concentrations. Brain Res 869: 216-219.
    • (2000) Brain Res , vol.869 , pp. 216-219
    • Martinez, M.1    Fernandez-Vivancos, E.2    Frank, A.3    de la Fuente, M.4    Hernanz, A.5
  • 52
    • 77954049661 scopus 로고    scopus 로고
    • Increase of SCF plasma concentration during donepezil treatment of patients with early Alzheimer's disease
    • Leyhe T, Hoffmann N, Stransky E, Laske C, (2009) Increase of SCF plasma concentration during donepezil treatment of patients with early Alzheimer's disease. Int J Neuropsychopharmacol 12: 1319-1326.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 1319-1326
    • Leyhe, T.1    Hoffmann, N.2    Stransky, E.3    Laske, C.4
  • 56
  • 57
    • 0036167595 scopus 로고    scopus 로고
    • Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia
    • Tarkowski E, Issa R, Sjogren M, Wallin A, Blennow K, Tarkowski A, et al. (2002) Increased intrathecal levels of the angiogenic factors VEGF and TGF-beta in Alzheimer's disease and vascular dementia. Neurobiol Aging 23: 237-243.
    • (2002) Neurobiol Aging , vol.23 , pp. 237-243
    • Tarkowski, E.1    Issa, R.2    Sjogren, M.3    Wallin, A.4    Blennow, K.5    Tarkowski, A.6
  • 58
    • 0032406078 scopus 로고    scopus 로고
    • Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor receptors I and II, and alpha1-antichymotrypsin
    • Lanzrein AS, Johnston CM, Perry VH, Jobst KA, King EM, Smith AD, (1998) Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease: interleukin-1beta, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-alpha, the soluble tumor necrosis factor receptors I and II, and alpha1-antichymotrypsin. Alzheimer Dis Assoc Disord 12: 215-227.
    • (1998) Alzheimer Dis Assoc Disord , vol.12 , pp. 215-227
    • Lanzrein, A.S.1    Johnston, C.M.2    Perry, V.H.3    Jobst, K.A.4    King, E.M.5    Smith, A.D.6
  • 59
    • 0034057048 scopus 로고    scopus 로고
    • Serum and cerebrospinal fluid cystatin C levels in vascular and Alzheimer's dementia
    • Kalman J, Marki-Zay J, Juhasz A, Santha A, Dux L, Janka Z, (2000) Serum and cerebrospinal fluid cystatin C levels in vascular and Alzheimer's dementia. Acta Neurol Scand 101: 279-282.
    • (2000) Acta Neurol Scand , vol.101 , pp. 279-282
    • Kalman, J.1    Marki-Zay, J.2    Juhasz, A.3    Santha, A.4    Dux, L.5    Janka, Z.6
  • 60
    • 19444377184 scopus 로고    scopus 로고
    • Oxidative imbalance and cathepsin D changes as peripheral blood biomarkers of Alzheimer disease: a pilot study
    • Straface E, Matarrese P, Gambardella L, Vona R, Sgadari A, Silveri MC, et al. (2005) Oxidative imbalance and cathepsin D changes as peripheral blood biomarkers of Alzheimer disease: a pilot study. FEBS Lett 579: 2759-2766.
    • (2005) FEBS Lett , vol.579 , pp. 2759-2766
    • Straface, E.1    Matarrese, P.2    Gambardella, L.3    Vona, R.4    Sgadari, A.5    Silveri, M.C.6
  • 61
    • 43149101531 scopus 로고    scopus 로고
    • Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study
    • Lopez OL, Kuller LH, Mehta PD, Becker JT, Gach HM, Sweet RA, et al. (2008) Plasma amyloid levels and the risk of AD in normal subjects in the Cardiovascular Health Study. Neurology 70: 1664-1671.
    • (2008) Neurology , vol.70 , pp. 1664-1671
    • Lopez, O.L.1    Kuller, L.H.2    Mehta, P.D.3    Becker, J.T.4    Gach, H.M.5    Sweet, R.A.6
  • 62
    • 33947683350 scopus 로고    scopus 로고
    • Genotype and plasma concentration of cystatin C in patients with late-onset Alzheimer disease
    • Chuo LJ, Sheu WH, Pai MC, Kuo YM, (2007) Genotype and plasma concentration of cystatin C in patients with late-onset Alzheimer disease. Dement Geriatr Cogn Disord 23: 251-257.
    • (2007) Dement Geriatr Cogn Disord , vol.23 , pp. 251-257
    • Chuo, L.J.1    Sheu, W.H.2    Pai, M.C.3    Kuo, Y.M.4
  • 64
    • 7244219832 scopus 로고    scopus 로고
    • Meningeal derived cerebrospinal fluid proteins in different forms of dementia: is a meningopathy involved in normal pressure hydrocephalus?
    • Brettschneider J, Riepe MW, Petereit HF, Ludolph AC, Tumani H, (2004) Meningeal derived cerebrospinal fluid proteins in different forms of dementia: is a meningopathy involved in normal pressure hydrocephalus? J Neurol Neurosurg Psychiatry 75: 1614-1616.
    • (2004) J Neurol Neurosurg Psychiatry , vol.75 , pp. 1614-1616
    • Brettschneider, J.1    Riepe, M.W.2    Petereit, H.F.3    Ludolph, A.C.4    Tumani, H.5
  • 65
    • 60349101411 scopus 로고    scopus 로고
    • Reduced levels of amyloid-beta-binding proteins in cerebrospinal fluid from Alzheimer's disease patients
    • Hansson SF, Andreasson U, Wall M, Skoog I, Andreasen N, Wallin A, et al. (2009) Reduced levels of amyloid-beta-binding proteins in cerebrospinal fluid from Alzheimer's disease patients. J Alzheimers Dis 16: 389-397.
    • (2009) J Alzheimers Dis , vol.16 , pp. 389-397
    • Hansson, S.F.1    Andreasson, U.2    Wall, M.3    Skoog, I.4    Andreasen, N.5    Wallin, A.6
  • 68
    • 2942737051 scopus 로고    scopus 로고
    • Binding of cystatin C to Alzheimer's amyloid beta inhibits in vitro amyloid fibril formation
    • Sastre M, Calero M, Pawlik M, Mathews PM, Kumar A, Danilov V, et al. (2004) Binding of cystatin C to Alzheimer's amyloid beta inhibits in vitro amyloid fibril formation. Neurobiol Aging 25: 1033-1043.
    • (2004) Neurobiol Aging , vol.25 , pp. 1033-1043
    • Sastre, M.1    Calero, M.2    Pawlik, M.3    Mathews, P.M.4    Kumar, A.5    Danilov, V.6
  • 69
    • 77149131537 scopus 로고    scopus 로고
    • Cystatin C protects neuronal cells from amyloid-beta-induced toxicity
    • Tizon B, Ribe EM, Mi W, Troy CM, Levy E, (2010) Cystatin C protects neuronal cells from amyloid-beta-induced toxicity. J Alzheimers Dis 19: 885-894.
    • (2010) J Alzheimers Dis , vol.19 , pp. 885-894
    • Tizon, B.1    Ribe, E.M.2    Mi, W.3    Troy, C.M.4    Levy, E.5
  • 70
    • 36549043900 scopus 로고    scopus 로고
    • Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models
    • Mi W, Pawlik M, Sastre M, Jung SS, Radvinsky DS, Klein AM, et al. (2007) Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models. Nat Genet 39: 1440-1442.
    • (2007) Nat Genet , vol.39 , pp. 1440-1442
    • Mi, W.1    Pawlik, M.2    Sastre, M.3    Jung, S.S.4    Radvinsky, D.S.5    Klein, A.M.6
  • 71
    • 62649160992 scopus 로고    scopus 로고
    • Plasminogen activator activity is inhibited while neuroserpin is up-regulated in the Alzheimer disease brain
    • Fabbro S, Seeds NW, (2009) Plasminogen activator activity is inhibited while neuroserpin is up-regulated in the Alzheimer disease brain. Journal of Neurochemistry 109: 303-315.
    • (2009) Journal of Neurochemistry , vol.109 , pp. 303-315
    • Fabbro, S.1    Seeds, N.W.2
  • 72
    • 0141641077 scopus 로고    scopus 로고
    • The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration
    • Melchor JP, Pawlak R, Strickland S, (2003) The tissue plasminogen activator-plasminogen proteolytic cascade accelerates amyloid-beta (Abeta) degradation and inhibits Abeta-induced neurodegeneration. J Neurosci 23: 8867-8871.
    • (2003) J Neurosci , vol.23 , pp. 8867-8871
    • Melchor, J.P.1    Pawlak, R.2    Strickland, S.3
  • 73
    • 34547131583 scopus 로고    scopus 로고
    • Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms
    • Cacquevel M, Launay S, Castel H, Benchenane K, Cheenne S, Buee L, et al. (2007) Ageing and amyloid-beta peptide deposition contribute to an impaired brain tissue plasminogen activator activity by different mechanisms. Neurobiol Dis 27: 164-173.
    • (2007) Neurobiol Dis , vol.27 , pp. 164-173
    • Cacquevel, M.1    Launay, S.2    Castel, H.3    Benchenane, K.4    Cheenne, S.5    Buee, L.6
  • 74
    • 0034660602 scopus 로고    scopus 로고
    • Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitation
    • Oyama R, Yamamoto H, Titani K, (2000) Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitation. Biochim Biophys Acta 1479: 91-102.
    • (2000) Biochim Biophys Acta , vol.1479 , pp. 91-102
    • Oyama, R.1    Yamamoto, H.2    Titani, K.3
  • 75
    • 77953679700 scopus 로고    scopus 로고
    • Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease
    • Cortes-Canteli M, Paul J, Norris EH, Bronstein R, Ahn HJ, Zamolodchikov D, et al. (2010) Fibrinogen and beta-amyloid association alters thrombosis and fibrinolysis: a possible contributing factor to Alzheimer's disease. Neuron 66: 695-709.
    • (2010) Neuron , vol.66 , pp. 695-709
    • Cortes-Canteli, M.1    Paul, J.2    Norris, E.H.3    Bronstein, R.4    Ahn, H.J.5    Zamolodchikov, D.6
  • 76
    • 34547791784 scopus 로고    scopus 로고
    • Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease
    • Paul J, Strickland S, Melchor JP, (2007) Fibrin deposition accelerates neurovascular damage and neuroinflammation in mouse models of Alzheimer's disease. J Exp Med 204: 1999-2008.
    • (2007) J Exp Med , vol.204 , pp. 1999-2008
    • Paul, J.1    Strickland, S.2    Melchor, J.P.3
  • 77
    • 0038079348 scopus 로고    scopus 로고
    • Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death
    • Su JH, Anderson AJ, Cribbs DH, Tu C, Tong L, Kesslack P, et al. (2003) Fas and Fas ligand are associated with neuritic degeneration in the AD brain and participate in beta-amyloid-induced neuronal death. Neurobiol Dis 12: 182-193.
    • (2003) Neurobiol Dis , vol.12 , pp. 182-193
    • Su, J.H.1    Anderson, A.J.2    Cribbs, D.H.3    Tu, C.4    Tong, L.5    Kesslack, P.6
  • 78
    • 77949338415 scopus 로고    scopus 로고
    • The FAS gene, brain volume, and disease progression in Alzheimer's disease
    • Erten-Lyons D, Jacobson A, Kramer P, Grupe A, Kaye J, (2010) The FAS gene, brain volume, and disease progression in Alzheimer's disease. Alzheimers Dement 6: 118-124.
    • (2010) Alzheimers Dement , vol.6 , pp. 118-124
    • Erten-Lyons, D.1    Jacobson, A.2    Kramer, P.3    Grupe, A.4    Kaye, J.5
  • 79
    • 0037125956 scopus 로고    scopus 로고
    • Metalloproteinase shedding of Fas ligand regulates beta-amyloid neurotoxicity
    • Ethell DW, Kinloch R, Green DR, (2002) Metalloproteinase shedding of Fas ligand regulates beta-amyloid neurotoxicity. Curr Biol 12: 1595-1600.
    • (2002) Curr Biol , vol.12 , pp. 1595-1600
    • Ethell, D.W.1    Kinloch, R.2    Green, D.R.3
  • 80
    • 0035478618 scopus 로고    scopus 로고
    • Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand
    • Morishima Y, Gotoh Y, Zieg J, Barrett T, Takano H, Flavell R, et al. (2001) Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. J Neurosci 21: 7551-7560.
    • (2001) J Neurosci , vol.21 , pp. 7551-7560
    • Morishima, Y.1    Gotoh, Y.2    Zieg, J.3    Barrett, T.4    Takano, H.5    Flavell, R.6
  • 81
    • 68549086855 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain
    • Burger S, Noack M, Kirazov LP, Kirazov EP, Naydenov CL, Kouznetsova E, et al. (2009) Vascular endothelial growth factor (VEGF) affects processing of amyloid precursor protein and beta-amyloidogenesis in brain slice cultures derived from transgenic Tg2576 mouse brain. Int J Dev Neurosci 27: 517-523.
    • (2009) Int J Dev Neurosci , vol.27 , pp. 517-523
    • Burger, S.1    Noack, M.2    Kirazov, L.P.3    Kirazov, E.P.4    Naydenov, C.L.5    Kouznetsova, E.6
  • 82
    • 67650149742 scopus 로고    scopus 로고
    • VEGF genetic variability is associated with increased risk of developing Alzheimer's disease
    • Del Bo R, Ghezzi S, Scarpini E, Bresolin N, Comi GP, (2009) VEGF genetic variability is associated with increased risk of developing Alzheimer's disease. J Neurol Sci 283: 66-68.
    • (2009) J Neurol Sci , vol.283 , pp. 66-68
    • Del Bo, R.1    Ghezzi, S.2    Scarpini, E.3    Bresolin, N.4    Comi, G.P.5
  • 83
    • 71649093560 scopus 로고    scopus 로고
    • Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR-2
    • Patel NS, Mathura VS, Bachmeier C, Beaulieu-Abdelahad D, Laporte V, Weeks O, et al. (2010) Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR-2. J Neurochem 112: 66-76.
    • (2010) J Neurochem , vol.112 , pp. 66-76
    • Patel, N.S.1    Mathura, V.S.2    Bachmeier, C.3    Beaulieu-Abdelahad, D.4    Laporte, V.5    Weeks, O.6
  • 84
    • 77049093949 scopus 로고    scopus 로고
    • Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients
    • Cheng X, Yang L, He P, Li R, Shen Y, (2010) Differential activation of tumor necrosis factor receptors distinguishes between brains from Alzheimer's disease and non-demented patients. J Alzheimers Dis 19: 621-630.
    • (2010) J Alzheimers Dis , vol.19 , pp. 621-630
    • Cheng, X.1    Yang, L.2    He, P.3    Li, R.4    Shen, Y.5
  • 85
    • 49349097514 scopus 로고    scopus 로고
    • Age-related differences in NFkappaB translocation and Bcl-2/Bax ratio caused by TNFalpha and Abeta42 promote survival in middle-age neurons and death in old neurons
    • Patel JR, Brewer GJ, (2008) Age-related differences in NFkappaB translocation and Bcl-2/Bax ratio caused by TNFalpha and Abeta42 promote survival in middle-age neurons and death in old neurons. Exp Neurol 213: 93-100.
    • (2008) Exp Neurol , vol.213 , pp. 93-100
    • Patel, J.R.1    Brewer, G.J.2
  • 86
  • 87
    • 78049424619 scopus 로고    scopus 로고
    • YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease
    • Craig-Schapiro R, Perrin RJ, Roe CM, Xiong C, Carter D, et al. (2010) YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease. Biol Psychiatry 68: 903-912.
    • (2010) Biol Psychiatry , vol.68 , pp. 903-912
    • Craig-Schapiro, R.1    Perrin, R.J.2    Roe, C.M.3    Xiong, C.4    Carter, D.5
  • 88
    • 0032539814 scopus 로고    scopus 로고
    • Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function
    • Guo Q, Christakos S, Robinson N, Mattson MP, (1998) Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function. Proc Natl Acad Sci U S A 95: 3227-3232.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3227-3232
    • Guo, Q.1    Christakos, S.2    Robinson, N.3    Mattson, M.P.4
  • 89
    • 0027499734 scopus 로고
    • Calbindin-D28k immunoreactivity and selective vulnerability to ischemia in the dentate gyrus of the developing rat
    • Goodman JH, Wasterlain CG, Massarweh WF, Dean E, Sollas AL, Sloviter RS, (1993) Calbindin-D28k immunoreactivity and selective vulnerability to ischemia in the dentate gyrus of the developing rat. Brain Res 606: 309-314.
    • (1993) Brain Res , vol.606 , pp. 309-314
    • Goodman, J.H.1    Wasterlain, C.G.2    Massarweh, W.F.3    Dean, E.4    Sollas, A.L.5    Sloviter, R.S.6
  • 90
    • 0026069449 scopus 로고
    • Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons
    • Mattson MP, Rychlik B, Chu C, Christakos S, (1991) Evidence for calcium-reducing and excito-protective roles for the calcium-binding protein calbindin-D28k in cultured hippocampal neurons. Neuron 6: 41-51.
    • (1991) Neuron , vol.6 , pp. 41-51
    • Mattson, M.P.1    Rychlik, B.2    Chu, C.3    Christakos, S.4
  • 91
    • 9044243405 scopus 로고    scopus 로고
    • Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons
    • Prehn JH, Bindokas VP, Jordan J, Galindo MF, Ghadge GD, Roos RP, et al. (1996) Protective effect of transforming growth factor-beta 1 on beta-amyloid neurotoxicity in rat hippocampal neurons. Mol Pharmacol 49: 319-328.
    • (1996) Mol Pharmacol , vol.49 , pp. 319-328
    • Prehn, J.H.1    Bindokas, V.P.2    Jordan, J.3    Galindo, M.F.4    Ghadge, G.D.5    Roos, R.P.6
  • 92
    • 0025358695 scopus 로고
    • Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases
    • Iacopino AM, Christakos S, (1990) Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases. Proc Natl Acad Sci U S A 87: 4078-4082.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 4078-4082
    • Iacopino, A.M.1    Christakos, S.2
  • 94
    • 0034784224 scopus 로고    scopus 로고
    • Relationship of calbindin D28K-immunoreactive cells and neuropathological changes in the hippocampal formation of Alzheimer's disease
    • Iritani S, Niizato K, Emson PC, (2001) Relationship of calbindin D28K-immunoreactive cells and neuropathological changes in the hippocampal formation of Alzheimer's disease. Neuropathology 21: 162-167.
    • (2001) Neuropathology , vol.21 , pp. 162-167
    • Iritani, S.1    Niizato, K.2    Emson, P.C.3
  • 95
    • 0034757594 scopus 로고    scopus 로고
    • Accumulation of calbindin in cortical pyramidal cells with ageing; a putative protective mechanism which fails in Alzheimer's disease
    • Greene JR, Radenahmad N, Wilcock GK, Neal JW, Pearson RC, (2001) Accumulation of calbindin in cortical pyramidal cells with ageing; a putative protective mechanism which fails in Alzheimer's disease. Neuropathol Appl Neurobiol 27: 339-342.
    • (2001) Neuropathol Appl Neurobiol , vol.27 , pp. 339-342
    • Greene, J.R.1    Radenahmad, N.2    Wilcock, G.K.3    Neal, J.W.4    Pearson, R.C.5


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