A zebrafish chemical suppressor screening identifies small molecule inhibitors of the Wnt/β-catenin pathway

Chemistry and Biology

Volumn 21, Issue 4, 2014, Pages 530-540

  Nishiya, Naoyuki ^a   Oku, Yusuke ^a   Kumagai, Yusuke ^a   Sato, Yuki ^a   Yamaguchi, Emi ^a   Sasaki, Akari ^a   Shoji, Momoko ^a   Ohnishi, Yukimi ^a   Okamoto, Hitoshi ^b   Uehara, Yoshimasa ^a  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; GGTI 286; TRANSFERASE INHIBITOR; UNCLASSIFIED DRUG; WNT PROTEIN; GERANYLGERANYLTRANSFERASE TYPE-I; LEUCINE; MOLECULAR LIBRARY; TRANSFERASE;

ANIMAL CELL; ANIMAL EMBRYO; ANIMAL EXPERIMENT; ARTICLE; CELLULAR DISTRIBUTION; DRUG IDENTIFICATION; DRUG SCREENING; EMBRYO; EYE DEVELOPMENT; FOLLOW UP; GENE SILENCING; GENETIC SCREENING; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; WNT SIGNALING PATHWAY; ZEBRA FISH; ANALOGS AND DERIVATIVES; ANATOMY AND HISTOLOGY; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; EYE; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; STRUCTURE ACTIVITY RELATION;

DANIO RERIO; MAMMALIA;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BETA CATENIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EYE; LEUCINE; MOLECULAR STRUCTURE; SMALL MOLECULE LIBRARIES; STRUCTURE-ACTIVITY RELATIONSHIP; WNT PROTEINS; WNT SIGNALING PATHWAY; ZEBRAFISH;

EID: 84899642292     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.02.015     Document Type: Article

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