DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs

Chemistry and Biology

Volumn 21, Issue 4, 2014, Pages 481-487

  Yin, Zhou ^a   Wang, Yao ^a   Whittell, Louise R ^a   Jergic, Slobodan ^a   Liu, Michael ^b   Harry, Elizabeth ^b   Dixon, Nicholas E ^a   Kelso, Michael J ^a   Beck, Jennifer L ^a   Oakley, Aaron J ^a  

^a UNIVERSITY OF WOLLONGONG   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BROMFENAC; CARPROFEN; DNA DIRECTED DNA POLYMERASE ALPHA; DNA DIRECTED DNA POLYMERASE GAMMA; DNA POLYMERASE III BETA SUBUNIT; DOUBLE STRANDED DNA; FLUFENAMIC ACID; PENTAPEPTIDE; SINGLE STRANDED DNA BINDING PROTEIN; TOLFENAMIC ACID; UNCLASSIFIED DRUG; VEDAPROFEN; ANTIINFECTIVE AGENT; BACTERIAL DNA; BETA SUBUNIT, DNA POLYMERASE III; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN KINASE INHIBITOR; PROTEIN SUBUNIT;

ACINETOBACTER BAYLYI; AGAR GEL ELECTROPHORESIS; ANTIBACTERIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; DNA REPAIR; DNA REPLICATION; DNA SEQUENCE; DNA SYNTHESIS INHIBITION; DRUG DNA BINDING; DRUG STRUCTURE; ESCHERICHIA COLI; FLUORESCENCE POLARIZATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; STAPHYLOCOCCUS AUREUS; X RAY CRYSTALLOGRAPHY; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PROTEIN SUBUNIT; STRUCTURE ACTIVITY RELATION;

ESCHERICHIA COLI;

ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DNA POLYMERASE III; DNA REPLICATION; DNA, BACTERIAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; MODELS, MOLECULAR; PROTEIN KINASE INHIBITORS; PROTEIN SUBUNITS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84899640878     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.02.009     Document Type: Article

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