Characterization of unstable products of flavin- and pterin-dependent enzymes by continuous-flow mass spectrometry

Biochemistry

Volumn 53, Issue 16, 2014, Pages 2672-2679

  Roberts, Kenneth M ^a   Tormos, José R ^b   Fitzpatrick, Paul F ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b ST MARY'S UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ENZYMES; ISOTOPES; NITROGEN COMPOUNDS; OXIDATION;

DEUTERIUM KINETIC ISOTOPE EFFECT; NONENZYMATIC HYDROLYSIS; PHENYLALANINE HYDROXYLASE; STEADY-STATE KINETICS; TANDEM MASS SPECTROMETRY; TRANSIENT FORMATION; TYROSINE HYDROXYLASE; UNSTABLE PRODUCT;

MASS SPECTROMETRY;

4A HYDROXYPTERIN; BENZALDEHYDE; BUTANE; CARBON; DEUTERIUM; FLAVOPROTEIN N ACETYLPOLYAMINE OXIDASE; IMINE; N,N' DIBENZYL 1,4 DIAMINOBUTANE; NITROGEN; PHENYLALANINE 4 MONOOXYGENASE; PTERIN DERIVATIVE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CONTINUOUS FLOW MASS SPECTROMETRY; COVALENT BOND; HYDROLYSIS; KINETICS; MASS SPECTROMETRY; OXIDATION; PRIORITY JOURNAL; STEADY STATE; TANDEM MASS SPECTROMETRY;

BENZYLAMINES; DEUTERIUM; FLAVINS; KINETICS; MASS SPECTROMETRY; OXIDATION-REDUCTION; PHENYLALANINE HYDROXYLASE; PTERINS; PUTRESCINE; SUBSTRATE SPECIFICITY; TYROSINE 3-MONOOXYGENASE;

EID: 84899629639     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500267c     Document Type: Article

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