TetX is a flavin-dependent monooxygenase conferring resistance to tetracycline antibiotics

Journal of Biological Chemistry

Volumn 279, Issue 50, 2004, Pages 52346-52352

  Yang, Wangrong ^a   Moore, Ian F ^a   Koteva, Kalinka P ^a   Bareich, David C ^a   Hughes, Donald W ^b   Wright, Gerard D ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; CATALYSIS; ENZYMES; HYDROXYLATION; PH EFFECTS; STOICHIOMETRY;

ANTIMICROBIAL AGENTS; ENZYME ACTIVITY; MICROBIAL TRANSLATION; RIBOSOMAL PROTECTION;

ENZYME KINETICS;

DIMETHYLANILINE MONOOXYGENASE; DIMETHYLANILINE MONOOXYGENASE TETX; FLAVINE ADENINE NUCLEOTIDE; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; TETRACYCLINE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYCLIZATION; DEGRADATION; ENZYME ACTIVITY; ESCHERICHIA COLI; HYDROXYLATION; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TRANSPOSON;

BACTERIAL PROTEINS; BACTEROIDES FRAGILIS; ESCHERICHIA COLI; FLAVOPROTEINS; KINETICS; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OXYGENASES; OXYTETRACYCLINE; RECOMBINANT PROTEINS; TETRACYCLINE RESISTANCE;

BACTEROIDES; ESCHERICHIA COLI; TRANSPOSONS;

EID: 10644286346     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409573200     Document Type: Article

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