Technological developments and future perspectives on graphene-based metamaterials: A primer for neurosurgeons

Neurosurgery

Volumn 74, Issue 5, 2014, Pages 499-516

  Mattei, Tobias A ^a   Rehman, Azeem A ^b  

^a Invision Health Brain and Spine Center   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Biomedical devices; Graphene; Metamaterials; Plasmonics; Translational research

Indexed keywords

CARBON; GRAPHENE; GRAPHENE OXIDE; LITHIUM ION; METAMATERIAL; NANOMATERIAL; QUANTUM DOT; UNCLASSIFIED DRUG; GRAPHITE;

BIOMEDICINE; CHEMICAL STRUCTURE; ELECTROCHEMISTRY; ELECTROMAGNETIC FIELD; ELECTRONICS; HUMAN; INTENSIVE CARE; MEDICAL DEVICE; MOLECULAR DIAGNOSIS; NERVE DEGENERATION; NERVE SURGERY; NEUROMONITORING; NEUROSURGEON; NEUROSURGERY; NONHUMAN; ONCOLOGY; PRIORITY JOURNAL; REVIEW; SPINE SURGERY; TECHNOLOGY; ARTHRODESIS; BIOMECHANICS; BRAIN COMPUTER INTERFACE; CHEMISTRY; DEVICES; FLUORESCENCE RESONANCE ENERGY TRANSFER; FORECASTING; MATERIALS TESTING; MOLECULAR PATHOLOGY; NANOTECHNOLOGY; NERVE REGENERATION; OXIDATION REDUCTION REACTION; PROCEDURES; SURFACE PROPERTY; SYNTHESIS; TRENDS;

ARTHRODESIS; BIOMECHANICAL PHENOMENA; BRAIN-COMPUTER INTERFACES; CARBON; FLUORESCENCE RESONANCE ENERGY TRANSFER; FORECASTING; GRAPHITE; HUMANS; MATERIALS TESTING; NANOTECHNOLOGY; NERVE REGENERATION; NEUROSURGERY; OXIDATION-REDUCTION; PATHOLOGY, MOLECULAR; SURFACE PROPERTIES;

EID: 84899622780     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0000000000000302     Document Type: Review

References (146)

1. Novoselov KS, Geim AK, Morozov SV, et al. Electric field effect in atomically thin carbon films. Science. 2004;306(5696):666-669.
2. Wallace PR. The band structure of graphite. Phys Rev. 1947;71:622-634.
3. Geim AK, Novoselov KS. The rise of graphene. Nat Mater. 2007;6(3):183-191.
4. Sakamoto J, van Heijst J, Lukin O, Schluter AD. Two-dimensional polymers: just a dream of synthetic chemists? Angew Chem Int Ed Engl. 2009;48(6):1030-1069.
5. Ando T, Nakaishi T, Saito R. Berry's phase and absence of back scattering in carbon nanotubes. J Phys Soc Jpn. 1998;67:2857-2862.
6. Zheng Y, Ando T. Hall conductivity of a two-dimensional graphite system. Phys Rev B. 2002;65:245420.
7. Kupferschmidt K. Research funding. Graphene and brain projects win European jackpot. Science. 2013;339(6119):497.
8. Stoller MD, Park S, Zhu Y, An J, Ruoff RS. Graphene-based ultracapacitors. Nano Lett. 2008;8(10):3498-3502.
9. Kim H, Abdala AA, Macosko CW. Graphene/Polymer nanocomposites. Macromolecules. 2010;43:6515-6530.
10. Zhu Y, James DK, Tour JM. New routes to graphene, graphene oxide and their related applications. Adv Mater. 2012;24(36):4924-4955.
11. Griffith AA. The phenomena of rupture and flow in solids. Philos Trans R Soc LondA. 1921;221:163-198.
12. Lee C, Wei X, Kysar JW, Hone J. Measurement of the elastic properties and intrinsic strength of monolayer graphene. Science. 2008;321(5887):385-388.
13. Lee GH, Cooper RC, An SJ, et al. High-strength chemical-vapor-deposited graphene and grain boundaries. Science. 2013;340(6136):1073-1076.
14. Class for Physics of the Royal Swedish Academy of Sciences. Scientific background on the Nobel Prize in Physics 2010. Graphene. The Official Web Site of the Nobel Prize. Available at: http://www. nobelprize. org/nobel- prizes/physics/laureates/2010/advanced-physicsprize2010. pdf. Accessed September 17, 2013.
15. Liu X, Metcalf TH, Robinson JT, Houston BH, Scarpa F. Shear modulus of monolayer graphene prepared by chemical vapor deposition. Nano Lett. 2012;12 (2):1013-1017.
16. Frank IW, Tanenbaum DM, van der Zande AM, McEuen PL. Mechanical properties of suspended graphene sheets. J Vas Sci Technol. 2007;25:2558-2561.
17. Kim Y, Lee J, Yeom MS, et al. Strengthening effect of single-atomic-layer graphene in metal-graphene nanolayered composites. Nat Commun. 2013;4:2114.
18. Nair RR, Blake P, Grigorenko AN, et al. Fine structure constant defines visual transparency of graphene. Science. 2008;320(5881):1308.
19. Loh KP, Bao Q, Eda G, Chhowalla M. Graphene oxide as a chemically tunable platform for optical applications. Nat Chem. 2010;2(12):1015-1024.
20. Bernardi M, Palummo M, Grossman JC. Extraordinary sunlight absorption and one nanometer thick photovoltaics using two-dimensional monolayer materials. Nano Lett. 2013;13(8):3664-3670.
21. Bitounis D, Ali-Boucetta H, Hong BH, Min DH, Kostarelos K. Prospects and challenges of graphene in biomedical applications. Adv Mater. 2013;25(16):2258-2268.
22. Day ES, Morton JG, West JL. Nanoparticles for thermal cancer therapy. J Biomech Eng. 2009;131(7):074001.
23. Liu L, Ni F, Zhang J, et al. Thermal analysis in the rat glioma model during directly multipoint injection hyperthermia incorporating magnetic nanoparticles. J Nanosci Nanotechnol. 2011;11(12):10333-10338.
24. Balandin AA, Ghosh S, Bao W, et al. Superior thermal conductivity of singlelayer graphene. Nano Lett. 2008;8(3):902-907.
25. Zhang J, Zhang L, Xu W. Surface plasmon polaritons: physics and applications. J Phys D Appl Phys. 2012;45:113001.
26. Barnes WL, Dereux A, Ebbesen TW. Surface plasmon subwavelength optics. Nature. 2003;424(6950):824-830.
27. Zheng YB, Kiraly B, Weiss PS, Huang TJ. Molecular plasmonics for biology and nanomedicine. Nanomedicine (Lond). 2012;7(5):751-770.
28. Wang L, Cai W, Zhang X, Xu J. Surface plasmons at the interface between graphene and Kerr-type nonlinear media. Opt Lett. 2012;37(13):2730-2732.
29. Timp W, Mirsaidov UM, Wang DX, Comer J, Aksimentiev A, Timp G. Nanopore sequencing: electrical measurements of the code of life. IEEE Trans Nanotechnol. 2010;9(3):281-294.
30. Chen D, Tang L, Li J. Graphene-based materials in electrochemistry. Chem Soc Rev. 2010;39(8):3157-3180.
31. Kasry A, Ardakani AA, Tulevski GS, Menges B, Copel M, Vyklicky L. Highly efficient fluorescence quenching with graphene. J Phys Chem. 2012; 116:2858-2862.
32. Colditz MJ, Jeffree RL. Aminolevulinic acid (ALA)-protoporphyrin IX fluorescence guided tumour resection. Part 1: clinical, radiological and pathological studies. J Clin Neurosci. 2012;19(11):1471-1474.
33. Lane BC, Cohen-Gadol AA. Fluorescein fluorescence use in the management of intracranial neoplastic and vascular lesions: a review and report of a new technique. Curr Drug Discov Technol. 2013;10(2):160-169.
34. Novoselov KS, Geim AK, Morozov SV, et al. Two-dimensional gas of massless dirac fermions in graphene. Nature. 2005;438(7065):197-200.
35. Chen JH, Jang C, Xiao S, Ishigami M, Fuhrer MS. Intrinsic and extrinsic performance limits of graphene devices on SiO2. Nat Nanotechnol. 2008;3(4) 206-209.
36. Geim AK. Graphene: status and prospects. Science. 2009;324(5934):1530- 1534.
37. Nagaosa N, Sinova J, Onoda S, MacDonald AH, Ong NP. Anomalous Hall effect. Rev Mod Phys. 2010;82:1539-1592.
38. Bolotin KI, Ghahari F, Shulman MD, Stormer HL, Kim P. Observation of the fractional quantum Hall effect in graphene. Nature. 2009;462(7270):196-199.
39. Katsnelson MI, Novoselov KS, Geim AK. Chiral tunneling and the Klein paradox in graphene. Nat Phys. 2006;2:620-625.
40. Steinberg H, Barak G, Yacoby A, Pfeiffer LN. Charge fractionalization in quantum wires. Nat Phys. 2007;4:116-119.
41. Guo G, Lin Z, Tu T, Cao G, Li X, Guo G. Quantum computation with graphene nanoribbon. New J Phys. 2009;11:123005.
42. Tsai JS. Toward a superconducting quantum computer. harnessing macroscopic quantum coherence. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86(4):275-292.
43. Barreiro JT, Müller M, Schindler P, et al. An open-system quantum simulator with trapped ions. Nature. 2011;470(7335):486-491.
44. Brennen GK, Caves CM, Jessen PS, Deutsch IH. Quantum logic gates in optical lattices. Phys Rev Lett. 1999;82:1060-1063.
45. Imamo-glu A, Awschalom DD, Burkard G, et al. Quantum information processing using quantum dot spins and cavity-QED. Phys Rev Lett. 1999;83:4204.
46. Jones JA. Quantum computing with NMR. Prog Nucl Magn Reson Spectrosc. 2011;59(2):91-120.
47. Lee B, Liu CY, Apuzzo ML. Quantum computing: a prime modality in neurosurgery's future. World Neurosurg. 2012;78(5):404-408.
48. Wiebe N, Braun D, Lloyd S. Quantum algorithm for data fitting. Phys Rev Lett. 2012;109(5):050505.
49. Onoda M, Nagaosa N. Quantized anomalous Hall effect in two-dimensional ferromagnets: quantum Hall effect in metals. Phys Rev Lett. 2003;90(20):206601.
50. Ha SH, Jeong YS, Lee YJ. Free standing reduced graphene oxide film cathodes for lithium ion batteries. ACS Appl Mater Interfaces. 2013;5(23):12295-12303.
51. Pesin D, MacDonald AH. Spintronics and pseudospintronics in graphene and topological insulators. Nat Mater. 2012;11(5):409-416.
52. Tombros N, Jozsa C, Popinciuc M, Jonkman HT, van Wees BJ. Electronic spin transport and spin precession in single graphene layers at room temperature. Nature. 2007;448(7153):571-574.
53. Castro Neto AH, Guinea F, Torres NMR, Novoselov KS, Geim AK. The electronic properties of graphene. Rev Mod Phys. 2009;81:109-162.
54. Hasan MZ, Kane CL. Topological insulators. Rev Mod Phys. 2010;82:3045-3067.
55. Seneor P, Dlubak B, Martin MB, Anana A, Jaffres H, Fert A. Spintronics with graphene. MRS Bull. 2012;37:1245-1254.
56. Das KT, Prusty S. Recent advances in applications of graphene. Int J Chem Sci Appl. 2013;4:39-55.
57. Xu M, Fujita D, Hanagata N. Perspectives and challenges of emerging singlemolecule DNA sequencing technologies. Small. 2009;5(23):2638-2649.
58. Weinmann HJ, Ebert W, Misselwitz B, Schmitt-Willich H. Tissue-specific MR contrast agents. Eur J Radiol. 2003;46(1):33-44.
59. Yang K, Hu L, Ma X, et al. Multimodal imaging guided photothermal therapy using functionalized graphene nanosheets anchored with magnetic nanoparticles. Adv Mater. 2012;24(14):1868-1872.
60. Sun X, Liu Z, Welsher K, et al. Nano-graphene oxide for cellular imaging and drug delivery. Nano Res. 2008;1(3):203-212.
61. Wang Y, Li Z, Hu D, Lin CT, Li J, Lin Y. Aptamer/graphene oxide nanocomplex for in situ molecular probing in living cells. J Am Chem Soc. 2010;132(27):9274-9276.
62. Qian J, Wang D, Cai FH, et al. Observation of multiphoton-induced fluorescence from graphene oxide nanoparticles and applications in in vivo functional bioimaging. Angew Chem Int Ed Engl. 2012;51(42):10570-10575.
63. Chen W, Yi P, Zhang Y, Zhang L, Deng Z, Zhang Z. Composites of aminodextran-coated Fe3O4 nanoparticles and graphene oxide for cellular magnetic resonance imaging. ACS Appl Mater Interfaces. 2011;3(10):4085-4091.
64. Yang K, Zhang S, Zhang G, Sun X, Lee ST, Liu Z. Graphene in mice: ultrahigh in vivo tumor uptake and efficient photothermal therapy. Nano Lett. 2010;10(9):3318-3323.
65. Yang K, Feng L, Shi X, Liu Z. Nano-graphene in biomedicine: theranostic applications. Chem Soc Rev. 2013;42(2):530-547.
66. Laaksonen P, Kainlauri M, Laaksonen T, et al. Interfacial engineering by proteins: exfoliation and functionalization of graphene by hydrophobins. Angew Chem Int Ed Engl. 2010;49(29):4946-4949.
67. Shen J, Shi M, Yan B, et al. Covalent attaching protein to graphene oxide via diimide-activated amidation. Colloids Surf B Biointerfaces. 2010;81(2):434-438.
68. Chen Y, Star A, Vidal S. Sweet carbon nanostructures: carbohydrate conjugates with carbon nanotubes and graphene and their applications. Chem Soc Rev. 2013;42(11):4532-4542.
69. Qi X, Tan C, Wei J, Zhang H. Synthesis of graphene-conjugated polymer nanocomposites for electronic device applications. Nanoscale. 2013;5(4):1440-1451.
70. Wang Z, Ge Z, Zheng X, et al. Polyvalent DNA-graphene nanosheets "click" conjugates. Nanoscale. 2012;4(2):394-399.
71. Cheng F, Chen W, Hu L, et al. Highly dispersible PEGylated graphene/Au composites as gene delivery vector and potential cancer therapeutic agent. JMater Chem B. 2013;1:4956-4962.
72. Zhang L, Xia J, Zhao Q, Liu L, Zhang Z. Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs. Small. 2010;6(4):537-644.
73. Liu Z, Robinson JT, Sun X, Dai H. PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. J Am Chem Soc. 2008;130(33):10876- 10877.
74. Abbott NJ. Blood-brain barrier structure and function and the challenges for CNS drug delivery. J Inherit Metab Dis. 2013;36(3):437-449.
75. Haar CP, Hebbar P, Wallace GC IV, et al. Drug resistance in glioblastoma: a mini review. Neurochem Res. 2012;37(6):1192-1200.
76. Robinson JT, Tabakman SM, Liang Y, et al. Ultrasmall reduced graphene oxide with high near-infrared absorbance for photothermal therapy. J Am Chem Soc. 2011;133(17):6825-6831.
77. Markovic ZM, Harhaji-Trajkovic LM, Todorovic-Markovic BM, et al. In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes. Biomaterials. 2011;32(4):1121-1129.
78. Dhawan V, DeGeorgia M. Neurointensive care biophysiological monitoring. J Neurointerv Surg. 2012;4(6):407-413.
79. Tisdall MM, Smith M. Cerebral microdialysis: research technique or clinical tool. Br J Anaesth. 2006;97(1):18-25.
80. Bhatia A, Gupta AK. Neuromonitoring in the intensive care unit. II. Cerebral oxygenation monitoring and microdialysis. Intensive Care Med. 2007;33(8):1322-1328.
81. De Georgia MA, Deogaonkar A. Multimodal monitoring in the neurological intensive care unit. Neurologist. 2005;11(1):45-54.
82. Rao GS, Durga P. Changing trends in monitoring brain ischemia: from intracranial pressure to cerebral oximetry. Curr Opin Anaesthesiol. 2011;24(5):487-494.
83. Artiles MS, Rout CS, Fisher TS. Graphene-based hybrid materials and devices for biosensing. Adv Drug Deliv Rev. 2011;63(14-15):1352-1360.
84. Lee MS, Lee K, Kim SY, et al. High-performance, transparent, and stretchable electrodes using graphene-metal nanowire hybrid structures. Nano Lett. 2013;13 (6):2814-2821.
85. Kim KS, Zhao Y, Jang H, et al. Large-scale pattern growth of graphene films for stretchable transparent electrodes. Nature. 2009;457(7230):706-710.
86. Gu H, Yu Y, Liu X, Ni B, Zhou T, Shi G. Layer-by-layer self-assembly of functionalized graphene nanoplates for glucose sensing in vivo integrated with on-line microdialysis system. Biosens Bioelectron. 2012;32(1):118-126.
87. Biju V. Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy. Chem Soc Rev. 2013;43(3):744-764.
88. Reina A, Jia X, Nezich D, et al. Large area, few-layer graphene films on arbitrary substrates by chemical vapor deposition. Nano Lett. 2009;9(1):30-35.
89. Heo C, Lee SY, Jo A, Jung S, Suh M, Lee YH. Flexible, transparent, and noncytotoxic graphene electric field stimulator for effective cerebral blood volume enhancement. ACS Nano. 2013;7(6):4869-4878.
90. Taghva A, Khalessi AA, Kim PE, Liu CY, Apuzzo ML. From atom to brain: applications of molecular imaging to neurosurgery. World Neurosurg. 2010;73(5):477-485.
91. Bayley H, Martin CR. Resistive-pulse sensing-from microbes to molecules. Chem Rev. 2000;100(7):2575-2594.
92. Venkatesan BM, Bashir R. Nanopore sensors for nucleic acid analysis. Nat Nanotechnol. 2011;6(10):615-624.
93. Nelson T, Zhang B, Prezhdo OV. Detection of nucleic acids with graphene nanopores: ab initio characterization of a novel sequencing device. Nano Lett. 2010;10(9):3237-3242.
94. Stine R, Robinson JT, Sheehan PE, Tamanaha CR. Real-time DNA detection using reduced graphene oxide field effect transistors. Adv Mater. 2010;22(46):5297-5300.
95. Bonanni A, Pumera M. Graphene platform for hairpin-DNA-based impedimetric genosensing. ACS Nano. 2011;5(3):2356-2361.
96. Wang Y, Li Y, Tang L, Lu J, Li J. Application of graphene-modified electrode for selective detection of dopamine. Electrochem Commun. 2009;11:889-892.
97. Adachi Y, Higuchi H, Watanabe K, Kazama T, Doi M, Sato S. The effect of halothane or sevoflurane anesthesia on the extracellular concentration of dopamine and its metabolites examined by in vivo microdialysis techniques [in Japanese]. Masui. 2006;55(12):1452-1458.
98. Leitl MD, Onvani S, Bowers MS, et al. Pain-related depression of the mesolimbic dopamine system in rats: expression, blockade by analgesics, and role of endogenous k-opioids. Neuropsychopharmacology. 2014;39(3)614-624.
99. Day RN, Davidson MW. Fluorescent proteins for FRET microscopy: monitoring protein interactions in living cells. Bioessays. 2012;34(5):341-350.
100. Zadran S, Standley S, Wong K, Otiniano E, Amighi A, Baudry M. Fluorescence resonance energy transfer (FRET)-based biosensors: visualizing cellular dynamics and bioenergetics. Appl Microbiol Biotechnol. 2012;96(4):895-902.
101. Dong H, Gao W, Yan F, Ji H, Ju H. Fluorescence resonance energy transfer between quantum dots and graphene oxide for sensing biomolecules. Anal Chem. 2010;82(13):5511-5517.
102. He S, Song B, Li D, et al. A graphene nanoprobe for rapid, sensitive, and multicolor fluorescent DNA analysis. Adv Funct Mater. 2010;20:453-459.
103. Lu Z, Zhang L, Deng Y, Li S, He N. Graphene oxide for rapid microRNA detection. Nanoscale. 2012;4(19):5840-5842.
104. Mattei TA, Fassett DR. Combined S-1 and S-2 sacral alar-iliac screws as a salvage technique for pelvic fixation after pseudarthrosis and lumbosacropelvic instability. J Neurosurg Spine. 2013;19(3):321-330.
105. Soultanis KC, Pyrovolou N, Zahos KA, et al. Late postoperative infection following spinal instrumentation: stainless steel versus titanium implants. J Surg Orthop Adv. 2008;17(3):193-199.
106. Knott PT, Mardjetko SM, Kim RH, et al. A comparison of magnetic and radiographic imaging artifact after using three types of metal rods: stainless steal, titanium, and vitallium. Spine J. 2010;10(9):789-794.
107. Smith JS, Shaffrey CI, Ames CP, et al. Assessment of symptomatic rod fracture after posterior instrumented fusion for adult spinal deformity. Neurosurgery. 2012;71(4):862-867.
108. Scheer JK, Tang JA, Smith JS, et al. Reoperation rates and impact on outcome in a large, prospective, multicenter, adult spinal deformity database. J Neurosurg Spine. 2013;19(4)464-470. doi: 10. 3171/2013. 7. SPINE12901.
109. Hu W, Peng C, Luo W, et al. Graphene-based antibacterial paper. ACS Nano. 2010;4(7):4317-4323.
110. Pu J, Mo Y, Wan S, Wang L. Fabrication of novel graphene-fullerene hybrid lubricating films based on self-assembly for MEMS applications. Chem Commun (Camb). 2013;50(4):469-471.
111. Benzel EC, Kayanja M, Fleischman A, Roy S. Spine biomechanics: fundamentals and future. Clin Neurosurg. 2006;53:98-105.
112. Lebedeva IV, Knizhnik AA, Popov AM, Lozovik YE, Potapkin BV. Modeling of graphene-based NEMS. Physica E. 2012;44:949-954.
113. Xiao W, Hu XY, Zeng W, Huang JH, Zhang YG, Luo ZJ. Rapid sciatic nerve regeneration of rats by a surface modified collagen-chitosan scaffold. Injury. 2013;44(7):941-946.
114. Wang X, He J, Wang Y, Cui FZ. Hyaluronic acid-based scaffold for central neural tissue engineering. Interf Focus. 2012;2(3):278-291.
115. Lu MC, Ho CY, Hsu SF, et al. Effects of electrical stimulation at different frequencies on regeneration of transected peripheral nerve. Neurorehabil Neural Repair. 2008;22(4):367-373.
116. Lu MC, Tsai CC, Chen SC, Tsai FJ, Yao CH, Chen YS. Use of electrical stimulation at different current levels to promote recovery after peripheral nerve injury in rats. J Trauma. 2009;67(5):1066-1072.
117. Wang WJ, Zhu H, Li F, Wan LD, Li HC, Ding WL. Electrical stimulation promotes motor nerve regeneration selectivity regardless of end-organ connection. J Neurotrauma. 2009;26(4):641-649.
118. Gordon T, Udina E, Verge VM, de Chaves EI. Brief electrical stimulation accelerates axon regeneration in the peripheral nervous system and promotes sensory axon regeneration in the central nervous system. Mot Control. 2009;13(4):412-441.
119. Zhou K, Thouas GA, Bernard CC, et al. Method to impart electro- and biofunctionality to neural scaffolds using graphene-polyelectrolyte multilayers. ACS Appl Mater Interfaces. 2012;4(9):4524-4531.
120. Li N, Zhang Q, Gao S, et al. Three-dimensional graphene foam as a biocompatible and conductive scaffold for neural stem cells. Sci Rep. 2013;3:1604.
121. Sahni D, Jea A, Meta JA, et al. Biocompatibility of pristine graphene for neuronal interface. J Neurosurg Pediatr. 2013;11(5):575-583.
122. Li N, Zhang X, Song Q, et al. The promotion of neurite sprouting and outgrowth of mouse hippocampal cells in culture by graphene substrates. Biomaterials. 2011;32(35):9374-9382.
123. Wang K, Ruan J, Song H, et al. Biocompatibility of graphene oxide. Nanoscale Res Lett. 2011;6:8.
124. Li Y, Yuan H, von dem Bussche A, et al. Graphene microsheets enter cells through spontaneous membrane penetration at edge asperities and corner sites. Proc Natl Acad Sci U S A. 2013;110(30):12295-12300.
125. Singh G, Rice P, Mahajan RL, McIntosh JR. Fabrication and characterization of a carbon nanotube-based nanoknife. Nanotechnology. 2009;20(9):095701.
126. Lee B, Liu CY, Apuzzo ML. A primer on brain-machine interfaces, concepts, and technology: a key element in the future of functional neurorestoration. World Neurosurg. 2013;79(3-4):457-471.
127. Otis B, Moritz C, Holleman J, et al. Circuit techniques for wireless brain interfaces. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:3213-3216.
128. Wang H, Nezich D, Kong J, Palacios T. Graphene frequency multipliers. IEEE Electron Device Lett. 2009;30:547-549.
129. Discher DE, Janmey P, Wang YL. Tissue cells feel and respond to the stiffness of their substrate. Science. 2005;310(5751):1139-1143.
130. Shuvo MA, Khan MA, Karim H, Morton P, Wilson T, Lin Y. Investigation of modified graphene for energy storage applications. ACS Appl Mater Interfaces. 2013;5(16):7881-7885.
131. Radhakrishnan G, Cardema JD, Adams PM, Kim HI, Foran B. Fabrication and electrochemical characterization of single and multi-layer graphene anodes for lithium-ion batteries. J Electrochem Soc. 2012;159(6):A752-A761.
132. Leuthardt EC, Schalk G, Moran D, Ojemann JG. The emerging world of motor neuroprosthetics: a neurosurgical perspective. Neurosurgery. 2006;59(1):1-14.
133. Whiting DM, Tomycz ND, Bailes J, et al. Lateral hypothalamic area deep brain stimulation for refractory obesity: a pilot study with preliminary data on safety, body weight, and energy metabolism. J Neurosurg. 2013;119(1):56-63.
134. Robison RA, Taghva A, Liu CY, Apuzzo ML. Surgery of the mind, mood, and conscious state: an idea in evolution. World Neurosurg. 2013;80(3-4):S2-S26.
135. Guridi J, Rodriguez-Oroz MC, Alegre M, Obeso JA. Hardware complications in deep brain stimulation: electrode impedance and loss of clinical benefit. Parkinsonism Relat Disord. 2012;18(6):765-769.
136. Royo-Gascon N, Wininger M, Scheinbeim JI, Firestein BL, Craelius W. Piezoelectric substrates promote neurite growth in rat spinal cord neurons. Ann Biomed Eng. 2013;41(1):112-122.
137. Yao L, Shanley L, McCaig C, Zhao M. Small applied electric fields guide migration of hippocampal neurons. J Cell Physiol. 2008;216(2):527-535.
138. Alexander JK, Fuss B, Colello RJ. Electric field-induced astrocyte alignment directs neurite outgrowth. Neuron Glia Biol. 2006;2(2):93-103.
139. Moriarty LJ, Borgens RB. An oscillating extracellular voltage gradient reduces the density and influences the orientation of astrocytes in injured mammalian spinal cord. J Neurocytol. 2001;30(1):45-57.
140. Sherafat MA, Heibatollahi M, Mongabadi S, Moradi F, Javan M, Ahmadiani A. Electromagnetic field stimulation potentiates endogenous myelin repair by recruiting subventricular neural stem cells in an experimental model of white matter demyelination. J Mol Neurosci. 2012;48(1):144-153.
141. Shapiro S, Borgens R, Pascuzzi R, et al. Oscillating field stimulation for complete spinal cord injury in humans: a phase 1 trial. J Neurosurg Spine. 2005;2(1):3-10.
142. Kirson ED, Dbalý V, Tovarys F, et al. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors. Proc Natl Acad Sci U S A. 2007;104(24):10152-10157.
143. Rulseh AM, Keller J, Klener J, et al. Long-term survival of patients suffering from glioblastoma multiforme treated with tumor-treating fields. World J Surg Oncol. 2012;24:220.
144. U. S. Food and Drug Administration (FDA). Tumor treatment fields. NovoTTF- 10A system. In: Summary of Safety and Effectiveness Data (SSED). Premarket Approval Application (PMA) No. P100034. Premarket Notification Database. Rockville, MD: FDA; 2011. Available online at: http://www. accessdata. fda. gov/ cdrh-docs/pdf10/P100034b. pdf. Accessed December 15, 2013.
145. Heo C, Yoo J, Lee S, et al. The control of neural cell-to-cell interactions through non-contact electrical field stimulation using graphene electrodes. Biomaterials. 2011;32(1):19-27.
146. Weiss NO, Zhou H, Liao L, et al. Graphene: an emerging electronic material. Adv Mater. 2012;24(43):5782-5825.