Novel derivatives of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4- tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with improved fluorescent and σ receptors binding properties

Journal of Medicinal Chemistry

Volumn 57, Issue 8, 2014, Pages 3314-3323

  Abate, Carmen ^a   Niso, Mauro ^a   Marottoli, Roberta ^a   Riganti, Chiara ^b   Ghigo, Dario ^b   Ferorelli, Savina ^a   Ossato, Giulia ^c   Perrone, Roberto ^a   Lacivita, Enza ^a   Lamb, Don C ^c   Berardi, Francesco ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 CYCLOHEXYL 4 [3 (5 METHOXY 1,2,3,4 TETRAHYDRONAPHTHALEN 1 YL) N PROPYL]PIPERAZINE; PB 28; PENTAZOCINE; TRACER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BREAST TUMOR; CONFOCAL MICROSCOPY; DRUG RECEPTOR BINDING; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; LIGAND BINDING; PHARMACOPHORE; RECEPTOR BINDING ASSAY; STRUCTURE ACTIVITY RELATION; TUMOR CELL;

ANIMALS; FLOW CYTOMETRY; FLUORESCENCE; GUINEA PIGS; HUMANS; LIGANDS; MALE; MCF-7 CELLS; PIPERAZINES; RATS; RECEPTORS, SIGMA;

EID: 84899565055     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401874n     Document Type: Article

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