2-Aminopyridine Derivatives as Potential σ2 Receptor Antagonists

ChemMedChem

Volumn 7, Issue 10, 2012, Pages 1847-1857

  Abate, Carmen ^a   Ferorelli, Savina ^a   Niso, Mauro ^a   Lovicario, Cesarea ^a   Infantino, Vittoria ^b   Convertini, Paolo ^a   Perrone, Roberto ^a   Berardi, Francesco ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF BASILICATA   (Italy)

Author keywords

receptors; 2 aminopyridines; Calcium; N cyclohexylpiperazines

Indexed keywords

1 (4 CYCLOHEXYLPIPERAZIN 1 YL) 4 [2(1H) OXO 3,4 DIHYDRO 1,8 NAPHTHYRIDIN 1 YL]BUTAN 1 ONE; 1 (4 CYCLOHEXYLPIPERAZIN 1 YL) 5 [2(1H) OXO 3,4 DIHYDRO 1,8 NAPHTHYRIDIN 1 YL]PENTAN 1 ONE; 1 (4 CYCLOHEXYLPIPERAZIN 1 YL) N ACETYL N (2 PYRIDYL) 4 AMINOBUTAN 1 ONE; 1 (4 CYCLOHEXYLPIPERAZIN 1 YL) N ACETYL N (2 PYRIDYL) 5 AMINOBUTAN 1 ONE; 1 [3 (4 CYCLOHEXYLPIPERAZIN 1 YL)PROPYL] 1,2,3,4 TETRAHYDRO 1,8 NAPHTHYRIDINE; 1 [3 (4 CYCLOHEXYLPIPERAZIN 1 YL)PROPYL] 3,4 DIHYDRO 1,8 NAPHTHYRIDIN 2 (1H) ONE; 1 [4 (4 CYCLOHEXYLPIPERAZIN 1 YL)BUTYL] 1,2,3,4 TETRAHYDRO 1,8 NAPHTHYRIDINE; 1 [5 (4 CYCLOHEXYLPIPERAZIN 1 YL)PENTYL] 1,2,3,4 TETRAHYDRO 1,8 NAPHTHYRIDINE; 2 AMINOPYRIDINE DERIVATIVE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N (2 PYRIDYL N OXIDE)PROPANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N (2 PYRIDYL)PROPANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N (4 METHOXY 2 PYRIDYL N OXIDE)PROPANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N (4 METHOXY 2 PYRIDYL)PROPANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N ETHYL N (2 PYRIDYL)BUTANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N ETHYL N (2 PYRIDYL)PENTANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N ETHYL N (2 PYRIDYL)PROPANAMINE; 3 (4 CYCLOHEXYLPIPERAZIN 1 YL) N ETHYL N (4 METHOXY 2 PYRIDYL)PROPANAMINE; 4 [3 (4 CYCLOHEXYLPIPERAZIN 1 YL)PROPYL] 2H PYRIDO[3,2 B] [1,4] OXAZIN 3 (4H) ONE; 4 [3 (4 CYCLOHEXYLPIPERAZIN 1 YL)PROPYL] 3,4 DIHYDRO 2H PYRIDO [3,2 B] [1,4] OXAZINE; CALCIUM ION; N [3 (4 CYCLOHEXYLPIPERAZIN 1 YL)PROPYL] N (2 PYRIDYL)ACETAMIDE; N [3 (4 CYCLOHEXYLPIPERAZIN 1 YL)PROPYL] N (4 METHOXY 2 PYRIDYL)ACETAMIDE; OPIATE ANTAGONIST; SIGMA OPIATE RECEPTOR ANTAGONIST; TETRALIN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CELL NUCLEUS; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL;

AMINOPYRIDINES; ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; KINETICS; LIGANDS; MCF-7 CELLS; MICE; RECEPTORS, SIGMA;

EID: 84866762588     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201200246     Document Type: Article

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