Quantification, Antioxidant and Antimicrobial Activity of Phenolics Isolated from Different Extracts of Capsicum frutescens (Pimenta Malagueta)

Molecules

Volumn 19, Issue 4, 2014, Pages 5434-5447

  Nascimento, Patrícia L A ^a   Nascimento, Talita C E S ^a   Ramos, Natália S M ^a   Silva, Girliane R ^a   Gomes, José Erick Galindo ^a   Falcão, Rosângela E A ^b   Moreira, Keila A ^a   Porto, Ana L F ^a   Silva, Tania M S ^a  

^a UNIVERSIDADE FEDERAL RURAL DE PERNAMBUCO   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

Author keywords

Antimicrobial; Antioxidant; Capsaicin; Capsicum frutescens; Chrysoeriol; Dihydrocapsaicin

Indexed keywords

2,2'-AZINO-DI-(3-ETHYLBENZOTHIAZOLINE)-6-SULFONIC ACID; 2,2-DIPHENYL-1-PICRYLHYDRAZYL; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; BENZOTHIAZOLE DERIVATIVE; BIPHENYL DERIVATIVE; FREE RADICAL; PHENOL DERIVATIVE; PICRIC ACID; PLANT EXTRACT; SCAVENGER; SULFONIC ACID DERIVATIVE;

CANDIDA ALBICANS; CHEMISTRY; DRUG EFFECTS; FRUIT; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; MICROBIAL SENSITIVITY TEST; PEPPER;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; BENZOTHIAZOLES; BIPHENYL COMPOUNDS; CANDIDA ALBICANS; CAPSICUM; FREE RADICAL SCAVENGERS; FREE RADICALS; FRUIT; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; MICROBIAL SENSITIVITY TESTS; PHENOLS; PICRATES; PLANT EXTRACTS; SULFONIC ACIDS;

EID: 84899542635     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules19045434     Document Type: Article

References (37)

1. Menichini, F.; Tundis, R.; Bonesi, M.; Loizzo, M.R.; Conforti, F.; Statti, G.; de Cindio, B.; Houghton, P.J.; Menichini, F. The influence of fruit ripening on the phytochemical contente and biological activity of Capsicum Chinese Jacq. Cv Habanero. Food Chem. 2009, 114, 553-560.
2. Barboza, G.E.; Bianchetti, L.B. Three new species of Capsicum (Solanaceae) and a key to the wild species from Brazil. Syst. Bot. 2005, 30, 863-871.
3. Garces-Claver, A.; Arnedo-Andres, M.S.; Abadia, J.; Gil-Ortega, R.; Alvarez-Fernandez, A. Determination of capsaicin and dihydrocapsaicin in Capsicum fruits by liquid chromatographyelectrospray/ time-of-flight mass spectrometry. J. Agric. Food Chem. 2006, 54, 9303-9311.
4. Cisneros-Pineda, O.; Torres-Tapia, L.W.; Gutierrez-Pacheco, L.C.; Contreras-Martin, F.; Gonzalez-Estrada, T.; Peraza-Sanchez, S.R. Capsaicinoids quantification in chili peppers cultivated in the state of Yucatan, Mexico. Food Chem. 2007, 104, 1755-1760.
5. Alvarez-Parrilla, E.; la Rosa, L.A.; Amarowicz, R.; Shahidi, F. Antioxidant activity of fresh and processed jalapeno and Serrano peppers. J. Agric. Food Chem. 2011, 59, 163-173.
6. Cushnie, T.P.T.; Lamb, A.J. Recent advances in understanding the antibacterial properties of flavonoids. Int. J. Antimicrob. Agents 2011, 38, 99-107.
7. Peterson, J.; Dwyer, J. Taxonomic classification helps identify flavonoid-containing foods on a semiquantitative food frequency questionnaire. J. Am. Diet. Assoc. 1998, 98, 677-685.
8. Bae, H.; Jayaprakasha, G.K.; Jifon, J.; Patil, B.S. Extraction efficiency and validation of an HPLC method for flavonoid analysis. Food Chem. 2012, 130, 751-758.
9. Othman, Z.A.A.; Ahmed, Y.B.H.; Habila, M.A.; Ghafar, A.A. Determination of Capsaicin and Dihydrocapsaicin in Capsicum Fruit Samples using High Performance Liquid Chromatography. Molecules 2011, 16, 8919-8929.
10. Dorantes, L.; Colmenero, R.; Hernandez, H.; Mota, L.; Jaramillo, M.E.; Fernandez, E.; Solano, C. Inhibition of growth of some foodborne pathogenic bacteria by Capsicum annum extracts. Int. J. Food Microbiol. 2000, 57, 125-128.
11. Sokmen, A.; Gulluce, M.; Akpulat, A.; Daferera, D.; Tepe, B.; Polissiou, M.; Sokmen, M.; Sahin, F. The in vitro antimicrobial and antioxidant activities of the essential oils and methanol extracts of endemic Thymus spathulifolius. Food Control. 2004, 15, 627-634.
12. Zimmer, A.R.; Leonardi, B.; Miron, D.; Schapoval, E.; Oliveira, J.R.; Gosmann, G. Antioxidant and anti-inflammatory proprerties of Capsicum baccatum: From traditional use to scientific approach. J. Ethnopharmacol. 2012, 139, 228-233.
13. Al-Fartosy, A.J.M.; Zearah, S.A. Antioxidant, antibacterial and cytotoxicity activities of flavonoid extract from Capsicum annum L. seeds. Iraqi Natl. J. Chem. 2013, 49, 100-112.
14. Materska, M.; Perucka, I. Antioxidant activity of the main phenolic compounds isolated from hot pepper fruit (Capsicum annuum L.). J. Agric. Food Chem. 2005, 53, 1750-1756.
15. Kozukue, N.; Han, J.S.; Kozukue, E.; Lee, S.J.; Kim, J.A.; Lee, K.R.; Levin, C.E.; Friedman, M. Analysis of eight capsaicinoids in peppers and pepper-containing foods by high-performance liquid chromatography and liquid chromatography-mass spectrometry. J. Agric. Food Chem. 2005, 53, 9172-9181.
16. Higashiguchi, F.; Nakamura, H.; Hayashi, H.; Kometani, T. Purification and structure determination of glucosides of capsaicin and dihydrocapsaicin from various Capsicum fruits. J. Agric. Food Chem. 2006, 54, 5948-5953.
17. Cichewicz, R.H.; Thorpe, P.A. The antimicrobial properties of chile peppers (Capsicum species) and their uses in Mayan medicine. J. Ethnopharmacol. 1996, 52, 61-70.
18. Jin, J.R.; Huiming, P.; Beibei, X.; Xia, Z.X. Separation and quantitative analysis of capsaicinoids in chili peppers by reversed-phase argentation LC. Chromatographia 2009, 70, 1011-1013.
19. Nascimento, P.L.A.; Nascimento, T.C.E.S.; Ramos, N.S.M.; Silva, G.R.; Camara, C.A.; Silva, T.M.S.; Moreira, K.A.; Porto, A.L.F. Antimicrobial and antioxidant activities of pimenta malagueta (Capsicum frutescens). Afr. J. Microbiol. Res. 2013, 7, 3526-3533.
20. Howard, L.R.; Talcott, S.T.; Brenes, C.H.; Villalon, B. Changes in phytochemical and antioxidant activity of selected pepper cultivars (Capsicum species) as influenced by maturity. J. Agric. Food Chem. 2000, 48, 1713-1720.
21. Zhuang, Y.; Chen, L.; Sun, L.; Cao, J. Bioactive characteristics and antioxidant activities of nine peppers. J. Funct. Foods 2012, 4, 331-338.
22. Oboh, G.; Ogunruku, O.O. Cyclophosphamide-induced oxidative stress in brain: Protective effect of hot short pepper (Capsicum frutescens L. var. abbreviatum). Exp. Toxicol. Pathol. 2010, 62, 227-233.
23. Chinn, M.S.; Sharma-Shivappa, R.R.; Cotter, J.L. Solvent extraction and quantification of capsaicinoids from Capsicum chinense. Food Bioprod. Process. 2011, 89, 340-345.
24. Tapia, J.C.; Garcia, R.; Escamilla, E.M.; Calva, C.; Rocha, J.A. Capsaicin recovery from a cell culture broth. Ind. Eng. Chem. Res. 1993, 32, 2242-2246.
25. Collins, M.D.; Wasmund, L.M.; Bosland, P.W. Improved Method for Quantifying Capsaicinoids in Capsicum Using High-performance Liquid Chromatography. Hortscience 1995, 30, 137-139.
26. Wahyuni, Y.; Ballester, A.R.; Sudarmonowati, E.; Bino, R.J.; Bovy, A.G. Metabolite biodiversity in pepper (Capsicum) fruits of thirty-two diverse accessions: Variation in health-related compounds and implications for breeding. Phytochemistry 2011, 72, 1358-1370.
27. Kirschbaum-Titze, P.; Hiepler, C.; Mueller-Seitz, E.; Petz, M. Pungency in paprika (Capsicum annuum). 1. Decrease of capsaicinoid content following cellular disruption. J. Agric. Food Chem. 2002, 50, 1260-1263.
28. Marin, A.; Ferreres, F.; Tomas-Barberan, F.A.; Gil, M.I. Characterization and Quantitation of Antioxidant Constituents of Sweet Pepper (Capsicum annuum L.). J. Agric. Food Chem. 2004, 52, 3861-3869.
29. Bamoniri, A.; Ebrahimabadi, A.H.; Mazoochi, A.; Behpour, M.; Kashi, F.J.; Batooli, H. Antioxidant and antimicrobial activity evaluation and essential oil analysis of Semenovia. tragioides Boiss. from Iran. Food Chem. 2010, 122, 553-558.
30. Flagan, S.F.; Leadbetter, J.R. Utilization of capsaicin and vanillylamine as growth substrates by Capsicum (hot pepper)-associated bacteria. Environ. Microbiol. 2006, 8, 560-565.
31. Molina-Torres, J.; Garcia-Chavez, A.; Ramirez-Chavez, E. Antimicrobial properties of alkamides present in flavouring plants traditionally used in Mesoamerica: Affinin and capsaicin. J. Ethnopharmacol. 1999, 64, 241-248.
32. Cos, P.; Vlietinck, A.J.; Berghe, D.V.; Maes, L. Anti-infective potential of natural products: How to develop a stronger in vitro 'proof-of-concept'. J. Ethnopharmacol. 2006, 106, 290-302.
33. Slinkard, K.; Singleton, V.L. Total phenol analyses: Automation and comparison with manual methods. Am. J. Enol. Viticult. 1977, 28, 49-55.
34. Silva, T.M.S.; Camara, C.A.; Lins, A.C.S.; Barbosa, J.M.; Silva, E.M.S.; Freitas, B.M.; Santos, F.A.R. Chemical composition and free radical scavenging activity of pollen loads from stingless bee Melipona. subnitida Ducke. J. Food Compos. Anal. 2006, 19, 507-511.
35. Re, R.; Pellegrini, N.; Proteggente, A.; Pannala, A.; Yang, M.; Rice-Evans, C. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic. Biol. Med. 1999, 26, 11231-1237.
36. National Committee for Clinical Laboratory Standards (NCCLS). Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically, In Approved Standand NCCLS Document M7-A6, 6th ed.; NCCLS: Wayne, NJ, USA, 2003; Volume 23, pp. 1-50.
37. Clinical and Laboratory Standarts Institute (CLSI). Reference Method for broth dilution antifungal susceptibility testing of yeasts, In Approved Standard M27-A3, 3rd ed.; CLSI: Wayne, NJ, USA, 2008; pp. 1-25.