Rare earth nanoprobes for functional biomolecular imaging and theranostics

Journal of Materials Chemistry B

Volumn 2, Issue 20, 2014, Pages 2958-2973

  Naczynski, Dominik J ^a,d   Tan, Mei Chee ^b,c   Riman, Richard E ^c   Moghe, Prabhas V ^d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SINGAPORE UNIVERSITY OF TECHNOLOGY AND DESIGN   (Singapore)

^c Piscataway   (United States)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG DELIVERY; MOLECULAR IMAGING; PROBES; RARE EARTHS;

BIOCHEMICAL PATHWAY; BIOMOLECULAR IMAGING; CANCER PATHOGENESIS; DEEP TISSUE IMAGING; ENHANCED SENSITIVITY; MOLECULAR MECHANISM; MOLECULAR PROFILING; MOLECULAR SIGNATURES;

NANOPROBES;

EID: 84899529313     PISSN: 20507518     EISSN: 2050750X     Source Type: Journal    
DOI: 10.1039/c4tb00094c     Document Type: Review

References (165)

1. L. M. F. Merlo J. W. Pepper B. J. Reid C. C. Maley Cancer as an evolutionary and ecological process Nat. Rev. Cancer 2006 6 924 935
2. C. Sotiriou M. J. Piccart Opinion-Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care? Nat. Rev. Cancer 2007 7 545 553
3. R. R. Anderson and E. V. Ross, Cutaneous Laser Surgery, Laser-tissue interactions, Mosby, Philadelphia, PA, 1994, vol. 9
4. E. E. Graves R. Weissleder V. Ntziachristos Fluorescence molecular imaging of small animal tumor models Curr. Mol. Med. 2004 4 419 430
5. A. J. Welch The Thermal Response of Laser Irradiated Tissue IEEE J. Quantum Electron. 1984 20 1471 1481
6. R. Matthes et al., Revision of guidelines on limits of exposure to laser radiation of wavelengths between 400 nm and 1.4 μm Health Phys. 2000 79 431 440
7. J. Culver W. Akers S. Achilefu Multimodality molecular imaging with combined optical and SPECT/PET modalities J. Nucl. Med. 2008 49 169 172
8. J. K. Willmann N. van Bruggen L. M. Dinkelborg S. S. Gambhir Molecular imaging in drug development Nat. Rev. Drug Discovery 2008 7 591 607
9. J. V. Frangioni In vivo near-infrared fluorescence imaging Curr. Opin. Chem. Biol. 2003 7 626 634
10. M. E. Davis Z. Chen D. M. Shin Nanoparticle therapeutics: an emerging treatment modality for cancer Nat. Rev. Drug Discovery 2008 7 771 782
11. P. Debbage W. Jaschke Molecular imaging with nanoparticles: giant roles for dwarf actors Histochem. Cell Biol. 2008 130 845 875
12. Nanostructured Materials For Biomedical Applications, ed., M.C. Tan, G.M. Chow, and, L. Ren, Transworld Research Network, 2009
13. M. C. Tan, G. M. Chow, L. Ren and Q. Zhang, in Nanoscience in Biomedicine, ed., D. Shi, Springer, Berlin Heidelberg, 2009, pp. 272-289
14. J. V. Frangioni New technologies for human cancer imaging J. Clin. Oncol. 2008 26 4012 4021
15. S. E. A. Gratton et al., The effect of particle design on cellular internalization pathways Proc. Natl. Acad. Sci. U. S. A. 2008 105 11613 11618
16. B. D. Chithrani A. A. Ghazani W. C. W. Chan Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells Nano Lett. 2006 6 662 668
17. A. Verma F. Stellacci Effect of Surface Properties on Nanoparticle-Cell Interactions Small 2010 6 12 21
18. R. A. Sperling W. J. Parak Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles Philos. Trans. R. Soc., A 2010 368 1333 1383
19. C. Bremer V. Ntziachristos R. Weissleder Optical-based molecular imaging: contrast agents and potential medical applications Eur. Radiol. 2003 13 231 243
20. S. A. Hilderbrand R. Weissleder Near-infrared fluorescence: application to in vivo molecular imaging Curr. Opin. Chem. Biol. 2010 14 71 79
21. R. Weissleder V. Ntziachristos Shedding light onto live molecular targets Nat. Med. 2003 9 123 128
22. F. S. Azar and X. Intes, Translational Multimodality Optical Imaging, Artech House, 2008
23. J. Beuthan O. Minet J. Helfmann M. Herrig G. Muller The spatial variation of the refractive index in biological cells Phys. Med. Biol. 1996 41 369 382
24. V. Backman et al., Polarized light scattering spectroscopy for quantitative measurement of epithelial cellular structures in situ IEEE J. Sel. Top. Quantum Electron. 1999 5 1019 1026
25. Z. Liu S. Tabakman K. Welsher H. Dai Carbon Nanotubes in Biology and Medicine: In vitro and In vivo Detection, Imaging and Drug Delivery Nano Res. 2009 2 85 120
26. F. Zhang R. Wang NIR Luminescent Nanomaterials for Biomedical Imaging J. Mater. Chem. B 2013 10.1039/c3tb21447h
27. A. M. Smith H. Duan A. M. Mohs S. Nie Bioconjugated quantum dots for in vivo molecular and cellular imaging Adv. Drug Delivery Rev. 2008 60 1226 1240
28. D. J. Naczynski et al., Rare-earth-doped biological composites as in vivo shortwave infrared reporters Nat. Commun. 2013 4 2199
29. 4/polymer core/shell/shell nanoparticles with significant enhancement of upconversion fluorescence Chem. Mater. 2007 19 341 343
30. R. Reisfeld and C. K. Jorgensen, in Lasers and Excited State of Rare Earths, Springer-Verlag, New York, 1977, pp. 64-122
31. R. Reisfeld and C. K. Jorgensen, in Handbook on the Physics and Chemistry of Rare Earth, ed., J. K. A. Gshneidner, and, L. Eyring, Elsevier Scientific Publishers B. V., New York, 1987, pp. 1-99
32. 3) J. Chem. Phys. 1989 90 3443 3457
33. J. Solé, L. Bausa and D. Jaque, An Introduction to the Optical Spectroscopy of Inorganic Solids, Wiley, 2005
34. B. Henderson and G. F. Imbusch, Optical Spectroscopy of Inorganic Solids, Oxford University Press, Incorporated, 2006
35. x J. Am. Chem. Soc. 2011 133 373 378
36. A. Kornienko et al., Highly NIR-Emissive Lanthanide Polyselenides Inorg. Chem. 2011 50 9184 9190
37. M. C. Tan D. J. Naczynski P. V. Moghe R. E. Riman Engineering the Design of Brightly-Emitting Luminescent Nanostructured Photonic Composite Systems Aust. J. Chem. 2013 66 1008 1020
38. G. A. Kumar C. W. Chen J. Ballato R. E. Riman Optical characterization of infrared emitting rare-earth-doped fluoride nanocrystals and their transparent nanocomposites Chem. Mater. 2007 19 1523 1528
39. 4:Yb, Er up-conversion nanocrystals J. Nanosci. Nanotechnol. 2010 10 1685 1692
40. T. Andelman M. C. Tan R. E. Riman Thermochemical engineering of hydrothermal crystallisation processes Mater. Res. Innovations 2010 14 9 15
41. 3:Nd nanoparticles J. Appl. Phys. 2009 106 063118/063111 063118/063112
42. 4:Yb, Er Nanocrystals J. Phys. Chem. C 2013 117 13297 13304
43. 3 for broadband 1.5 μm amplification J. Appl. Phys. 2004 95 40 47
44. R. E. Riman G. A. Kumar V. Atakan J. G. Brennan J. Ballato Engineered solution synthesis of rare-earth nanomaterials and their optical properties Proc. SPIE-Int. Soc. Opt. Eng. 2007 6707 670707/670701 670707/670711
45. 4:Yb, Er nanocrystals from a unique delayed nucleation pathway monitored with upconversion spectroscopy J. Phys. Chem. C 2007 111 13730 13739
46. F. Zhang et al., Uniform nanostructured arrays of sodium rare-earth fluorides for highly efficient multicolor upconversion luminescence Angew. Chem., Int. Ed. 2007 46 7976 7979
47. 4 Fabricated by Hydrothermal Process: Effects of pH Values and Fluoride Sources ChemInform 2007 19 4933 4942
48. 3 nanoparticles IEEE Trans. Nanotechnol. 2006 5 123 128
49. 4:Yb, Er infrared-to-visible up-conversion phosphors Nano Lett. 2004 4 2191 2196
50. 3+via thermal decomposition of lanthanide trifluoroacetate precursors J. Am. Chem. Soc. 2006 128 7444 7445
51. G. S. Yi et al., Synthesis and characterization of high-efficiency nanocrystal up-conversion phosphors: ytterbium and erbium codoped lanthanum molybdate Chem. Mater. 2002 14 2910 2914
52. 3+, phosphors of controlled size and morphology Adv. Mater. 2005 17 2119 2123
53. 4 nanocrystals Adv. Mater. 2004 16 2102 2105
54. F. van de Rijke et al., Up-converting phosphor reporters for nucleic acid microarrays Nat. Biotechnol. 2001 19 273 276
55. T. Zako et al., Development of Near Infrared-Fluorescent Nanophosphors and Applications for Cancer Diagnosis and Therapy J. Nanomater. 2010 10.1155/2010/491471
56. P. N. Prasad, in Nanophotonics, John Wiley & Sons, Inc., 2004, pp. 129-151
57. 3+ Doped Fluoride Nanophosphors Nano Lett. 2008 8 3834 3838
58. F. Wang X. G. Liu Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals Chem. Soc. Rev. 2009 38 976 989
59. J. Chen J. X. Zhao Upconversion Nanomaterials: Synthesis, Mechanism, and Applications in Sensing Sensors 2012 12 2414 2435
60. F. Auzel Upconversion and anti-Stokes processes with f and d ions in solids Chem. Rev. 2004 104 139 173
61. O. Ballato R. E. Riman E. Snitzer Sol-gel synthesis of rare-earth-doped lanthanum halides for highly efficient 1.3 μm optical amplification Opt. Lett. 1997 22 691 693
62. V. Singh et al., Infrared emissions, visible up-conversion, thermoluminescence and defect centres in Er3Al5O12 phosphor obtained by solution combustion reaction Appl. Phys. B: Lasers Opt. 2010 101 631 638
63. B. van Saders L. Al-Baroudi M. C. Tan R. E. Riman Rare-earth doped particles with tunable infrared emissions for biomedical imaging Opt. Mater. Express 2013 3 566 573
64. 3 nanoparticles with no visible upconversion Opt. Express 2009 17 15904 15910
65. R. C. Powell, Physics of Solid-State Laser Materials, AIP Press/Springer, 1998
66. S. Sudo, Optical Fiber Amplifiers: Materials, Devices, and Applications, Artech House, 1997
67. 3 Nanoparticles as Fluorescent Probes Eur. J. Inorg. Chem. 2010 2010 2673 2677
68. M. Kamimura N. Kanayama K. Tokuzen K. Soga Y. Nagasaki Near-infrared (1550 nm) in vivo bioimaging based on rare-earth doped ceramic nanophosphors modified with PEG-b-poly(4-vinylbenzylphosphonate) Nanoscale 2011 3 3705 3713
69. G. Blasse and B. C. Grabmaier, Luminescent materials: with 31 tables, Springer, Berlin, Heidelberg [u.a.], 1994
70. 4:Yb-Er ACS Appl. Mater. Interfaces 2011 3 3910 3915
71. S. Hirano K. T. Suzuki Exposure, metabolism, and toxicity of rare earths and related compounds Environ. Health Perspect. 1996 104 85 95
72. 4 upconversion fluorescent nanocrystals Biomaterials 2008 29 4122 4128
73. 4:Yb, Tm nanocrystals Biomaterials 2011 32 9059 9067
74. J. Liu D. M. Aruguete M. Murayama M. F. Hochella, Jr Influence of size and aggregation on the reactivity of an environmentally and industrially relevant nanomaterial (PbS) Environ. Sci. Technol. 2009 43 8178 8183
75. A. K. Iyer G. Khaled J. Fang H. Maeda Exploiting the enhanced permeability and retention effect for tumor targeting Drug Discovery Today 2006 11 812 818
76. F. Yuan et al., Vascular-Permeability in a Human Tumor Xenograft-Molecular-Size Dependence and Cutoff Size Cancer Res. 1995 55 3752 3756
77. P. Couvreur C. Vauthier Nanotechnology: Intelligent design to treat complex disease Pharm. Res. 2006 23 1417 1450
78. S. K. Hobbs et al., Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment Proc. Natl. Acad. Sci. U. S. A. 1998 95 4607 4612
79. V. P. Torchilin Recent advances with liposomes as pharmaceutical carriers Nat. Rev. Drug Discovery 2005 4 145 160
80. 2S nanoparticles J. Mater. Sci.: Mater. Med. 2009 20 2091 2103
81. 2S nanoparticles for potential cancer therapy: cytotoxicity, in vitro carcinogenicity, and cellular uptake J. Biomed. Mater. Res., Part A 2008 85 787 796
82. T. Nomura N. Koreeda F. Yamashita Y. Takakura M. Hashida Effect of particle size and charge on the disposition of lipid carriers after intratumoral injection into tissue-isolated tumors Pharm. Res. 1998 15 128 132
83. S. Hu-Lieskovan J. D. Heidel D. W. Bartlett M. E. Davis T. J. Triche Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma Cancer Res. 2005 65 8984 8992
84. 4 nanoparticles with PEG-phosphate ligands for NIR (800 nm) biolabeling within the biological window Langmuir 2010 26 1157 1164
85. N. M. Idris et al., Tracking transplanted cells in live animal using upconversion fluorescent nanoparticles Biomaterials 2009 30 5104 5113
86. R. Abdul Jalil Y. Zhang Biocompatibility of silica coated NaYF(4) upconversion fluorescent nanocrystals Biomaterials 2008 29 4122 4128
87. 4 Nanocrystals Adv. Funct. Mater. 2009 19 853 859
88. 4 nanocrystals in aqueous solution displaying strong up-conversion emission Chem. Mater. 2007 19 1396 1400
89. 4 nanocrystals with multicolor upconversion fluorescence emission Angew. Chem., Int. Ed. 2006 45 7732 7735
90. 4 nanoparticles with upconversion fluorescence Nanotechnology 2006 17 5786 5791
91. D. K. Chatteriee A. J. Rufalhah Y. Zhang Upconversion fluorescence imaging of cells and small animals using lanthanide doped nanocrystals Biomaterials 2008 29 937 943
92. W. T. Godbey K. K. Wu A. G. Mikos Poly(ethylenimine) and its role in gene delivery J. Controlled Release 1999 60 149 160
93. S. M. Moghimi A. C. Hunter J. C. Murray Long-circulating and target-specific nanoparticles: Theory to practice Pharmacol. Rev. 2001 53 283 318
94. H. S. Choi et al., Design considerations for tumour-targeted nanoparticles Nat. Nanotechnol. 2010 5 42 47
95. X. Montet M. Funovics K. Montet-Abou R. Weissleder L. Josephson Multivalent effects of RGD peptides obtained by nanoparticle display J. Med. Chem. 2006 49 6087 6093
96. M. E. Davis et al., Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles Nature 2010 464 1067 U1140
97. L. Xiong T. Yang Y. Yang C. Xu F. Li Long-term in vivo biodistribution imaging and toxicity of polyacrylic acid-coated upconversion nanophosphors Biomaterials 2010 31 7078 7085
98. S. Hirano K. T. Suzuki Exposure, metabolism, and toxicity of rare earths and related compounds Environ. Health Perspect. 1996 104 85
99. S. A. Hilderbrand F. Shao C. Salthouse U. Mahmood R. Weissleder Upconverting luminescent nanomaterials: application to in vivo bioimaging Chem. Commun. 2009 4188 4190
100. H. Hu et al., Multimodal-luminescence core-shell nanocomposites for targeted imaging of tumor cells Chem.-Eur. J. 2009 15 3577 3584
101. 4 upconversion fluorescent nanocrystals Biomaterials 2008 29 4122 4128
102. S. Cui et al., In vivo targeted deep-tissue photodynamic therapy based on near-infrared light triggered upconversion nanoconstruct ACS Nano 2013 7 676 688
103. 4:Yb/Er nanocrystals by folic acid-chitosan conjugates for targeted lung cancer cell imaging J. Mater. Chem. 2011 21 7661 7667
104. D. J. Naczynski et al., Albumin nanoshell encapsulation of near-infrared-excitable rare-earth nanoparticles enhances biocompatibility and enables targeted cell imaging Small 2010 6 1631 1640
105. M. Cui et al., Multifunctional Albumin Nanoparticles As Combination Drug Carriers for Intra-Tumoral Chemotherapy Adv. Healthcare Mater. 2013 2 1236 1245
106. M. Yu et al., Laser scanning up-conversion luminescence microscopy for imaging cells labeled with rare-earth nanophosphors Anal. Chem. 2009 81 930 935
107. V. Ntziachristos C. Bremer R. Weissleder Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging Eur. Radiol. 2003 13 195 208
108. J. V. Frangioni In vivo near-infrared fluorescence imaging Curr. Opin. Chem. Biol. 2003 7 626 634
109. P. N. Prasad, in Introduction to Biophotonics, John Wiley & Sons, Inc., 2004, pp. 1-10
110. N. Billinton A. W. Knight Seeing the wood through the trees: A review of techniques for distinguishing green fluorescent protein from endogenous autofluorescence Anal. Biochem. 2001 291 175 197
111. A. N. Bashkatov E. A. Genina V. I. Kochubey V. V. Tuchin Optical properties of the subcutaneous adipose tissue in the spectral range 400-2500 nm Opt. Spectrosc. 2005 99 836 842
112. G. Zonios J. Bykowski N. Kollias Skin melanin, hemoglobin, and light scattering properties can be quantitatively assessed in vivo using diffuse reflectance spectroscopy J. Invest. Dermatol. 2001 117 1452 1457
113. Y. T. Lim et al., Selection of quantum dot wavelengths for biomedical assays and imaging Mol. Imaging 2003 2 50 64
114. A. M. Smith M. C. Mancini S. Nie Bioimaging: second window for in vivo imaging Nat. Nanotechnol. 2009 4 710 711
115. A. L. Rogach A. Eychmuller S. G. Hickey S. V. Kershaw Infrared-emitting colloidal nanocrystals: synthesis, assembly, spectroscopy, and applications Small 2007 3 536 557
116. R. Hardman A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors Environ. Health Perspect. 2006 114 165 172
117. K. Welsher et al., A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice Nat. Nanotechnol. 2009 4 773 780
118. H. J. Dai et al., High performance in vivo near-IR (>1 μm) imaging and photothermal cancer therapy with carbon nanotubes Nano Res. 2010 3 779 793
119. E. Schrock et al., Multicolor spectral karyotyping of human chromosomes Science 1996 273 494 497
120. I. L. Medintz H. T. Uyeda E. R. Goldman H. Mattoussi Quantum dot bioconjugates for imaging, labelling and sensing Nat. Mater. 2005 4 435 446
121. M. C. Tan J. Connolly R. E. Riman Optical Efficiency of Short Wave Infrared Emitting Phosphors J. Phys. Chem. C 2011 115 17952 17957
122. A. Kennedy et al., Recommendations for radioembolization of hepatic malignancies using yttrium-90 microsphere brachytherapy: a consensus panel report from the radioembolization brachytherapy oncology consortium Int. J. Radiat. Oncol., Biol., Phys. 2007 68 13 23
123. K. Welsher S. P. Sherlock H. Dai Deep-tissue anatomical imaging of mice using carbon nanotube fluorophores in the second near-infrared window Proc. Natl. Acad. Sci. U. S. A. 2011 108 8943 8948
124. R. M. Levenson D. T. Lynch H. Kobayashi J. M. Backer M. V. Backer Multiplexing with multispectral imaging: From mice to microscopy ILAR J. 2008 49 78 88
125. C. L. Zavaleta et al., Multiplexed imaging of surface enhanced Raman scattering nanotags in living mice using noninvasive Raman spectroscopy Proc. Natl. Acad. Sci. U. S. A. 2009 106 13511 13516
126. Y. Zhang Y. Tang X. Liu L. Zhang Y. Lv A highly sensitive upconverting phosphors-based off-on probe for the detection of glutathione Sens. Actuators, B 2013 185 363 369
127. J. Peng Y. Wang J. Wang X. Zhou Z. Liu A new biosensor for glucose determination in serum based on up-converting fluorescence resonance energy transfer Biosens. Bioelectron. 2011 28 414 420
128. 4 nanocrystals Angew. Chem., Int. Ed. Engl. 2011 50 6306 6310
129. L. Wang Y. Li Green upconversion nanocrystals for DNA detection Chem. Commun. 2006 2557 2559
130. F. Vetrone et al., Temperature Sensing Using Fluorescent Nanothermometers ACS Nano 2010 4 3254 3258
131. C. Wang L. Cheng Z. Liu Drug delivery with upconversion nanoparticles for multi-functional targeted cancer cell imaging and therapy Biomaterials 2011 32 1110 1120
132. 2 Nanospheres as Carriers for Drug Delivery J. Phys. Chem. C 2011 115 15801 15811
133. H. Xu et al., Polymer encapsulated upconversion nanoparticle/iron oxide nanocomposites for multimodal imaging and magnetic targeted drug delivery Biomaterials 2011 32 9364 9373
134. L. Cheng et al., Highly-sensitive multiplexed in vivo imaging using pegylated upconversion nanoparticles Nano Res. 2010 3 722 732
135. L. Xiong et al., High Contrast Upconversion Luminescence Targeted Imaging in vivo Using Peptide-Labeled Nanophosphors Anal. Chem. 2009 81 8687 8694
136. Q. Liu W. Feng T. Yang T. Yi F. Li Upconversion luminescence imaging of cells and small animals Nat. Protoc. 2013 8 2033 2044
137. K. Liu et al., Covalently assembled NIR nanoplatform for simultaneous fluorescence imaging and photodynamic therapy of cancer cells ACS Nano 2012 6 4054 4062
138. N. M. Idris et al., In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers Nat. Med. 2012 18 1580 1585
139. H. S. Qian H. C. Guo P. C. Ho R. Mahendran Y. Zhang Mesoporous-silica- coated up-conversion fluorescent nanoparticles for photodynamic therapy Small 2009 5 2285 2290
140. G. Shan R. Weissleder S. A. Hilderbrand Upconverting organic dye doped core-shell nano-composites for dual-modality NIR imaging and photo-thermal therapy Theranostics 2013 3 267 274
141. L. Cheng et al., Facile preparation of multifunctional upconversion nanoprobes for multimodal imaging and dual-targeted photothermal therapy Angew. Chem., Int. Ed. Engl. 2011 50 7385 7390
142. 3+@Ag core-shell nanocomposites: integration of upconversion imaging and photothermal therapy J. Mater. Chem. 2011 21 6193 6200
143. 3+@hydrogel core-shell hybrid microspheres ACS Nano 2012 6 3327 3338
144. Y. Yang B. Velmurugan X. Liu B. Xing NIR photoresponsive crosslinked upconverting nanocarriers toward selective intracellular drug release Small 2013 9 2937 2944
145. E. L. Kaijzel G. van der Pluijm C. W. G. M. Lowik Whole-body optical Imaging in animal models to assess cancer development and progression Clin. Cancer Res. 2007 13 3490 3497
146. M. F. Kircher et al., A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle Nat. Med. 2012 18 829
147. J. Kim Y. Piao T. Hyeon Multifunctional nanostructured materials for multimodal imaging, and simultaneous imaging and therapy Chem. Soc. Rev. 2009 38 372 390
148. M. F. Kircher U. Mahmood R. S. King R. Weissleder L. Josephson A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation Cancer Res. 2003 63 8122 8125
149. M. Nahrendorf et al., Hybrid PET-optical imaging using targeted probes Proc. Natl. Acad. Sci. U. S. A. 2010 107 7910 7915
150. 5:Yb/Er nanoprobes for multi-modal upconversion fluorescent, in vivo X-ray computed tomography and biomagnetic imaging Biomaterials 2012 33 9232 9238
151. G. Pratx C. M. Carpenter C. Sun L. Xing X-ray luminescence computed tomography via selective excitation: a feasibility study IEEE Trans. Med. Imag. 2010 29 1992 1999
152. H. Xing et al., Multifunctional nanoprobes for upconversion fluorescence, MR and CT trimodal imaging Biomaterials 2012 33 1079 1089
153. J.-N. Liu et al., Simultaneous nuclear imaging and intranuclear drug delivery by nuclear-targeted multifunctional upconversion nanoprobes Biomaterials 2012 33 7282 7290
154. J. Zhou et al., Dual-modality in vivo imaging using rare-earth nanocrystals with near-infrared to near-infrared (NIR-to-NIR) upconversion luminescence and magnetic resonance properties Biomaterials 2010 31 3287 3295
155. 3+ nanophosphors for upconversion luminescence, MR, and PET imaging of tumor angiogenesis J. Nucl. Med. 2013 54 96 103
156. 4 nanophosphors for multimodality PET/MR/UCL imaging Biomaterials 2011 32 1148 1156
157. L. V. Wang Multiscale photoacoustic microscopy and computed tomography Nat. Photonics 2009 3 503 509
158. D. M. McDonald P. L. Choyke Imaging of angiogenesis: from microscope to clinic Nat. Med. 2003 9 713 725
159. J. Sanz Z. A. Fayad Imaging of atherosclerotic cardiovascular disease Nature 2008 451 953 957
160. R. Murthy et al., Yttrium-90 microsphere therapy for hepatic malignancy: devices, indications, technical considerations, and potential complications Radiographics 2005 25 suppl. 1 S41 S55
161. N. Desai Nanoparticle albumin bound (nab) technology: targeting tumors through the endothelial gp60 receptor and SPARC Nanomedicine: Nanotechnology, Biology and Medicine 2007 3 339
162. N. Desai V. Trieu B. Damascelli P. Soon-Shiong SPARC Expression Correlates with Tumor Response to Albumin-Bound Paclitaxel in Head and Neck Cancer Patients Transl. Oncol. 2009 2 59 64
163. O. L. Podhajcer et al., The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host Cancer Metastasis Rev. 2008 27 691 705
164. J. E. Schnitzer P. Oh Antibodies to SPARC Inhibit Albumin Binding to SPARC, Gp60, and Microvascular Endothelium Am. J. Physiol. 1992 263 H1872 H1879
165. S. M. Vogel R. D. Minshall M. Pilipovic C. Tiruppathi A. B. Malik Albumin uptake and transcytosis in endothelial cells in vivo induced by albumin-binding protein Am. J. Physiol. 2001 281 L1512 L1522