c-Jun transactivates Puma gene expression to promote osteoarthritis

Molecular Medicine Reports

Volumn 9, Issue 5, 2014, Pages 1606-1612

  Lu, Huading ^a   Hou, Gang ^a   Zhang, Yongkai ^a   Dai, Yuhu ^a   Zhao, Huiqing ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; JNK c Jun; Osteoarthritis; PUMA

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; INTERLEUKIN 1BETA; MESSENGER RNA; PROTEIN BCL 2; PUMA PROTEIN; STRESS ACTIVATED PROTEIN KINASE;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL SUSPENSION; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME INHIBITION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; OSTEOARTHRITIS; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

AGED; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELLS, CULTURED; CHONDROCYTES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MIDDLE AGED; OSTEOARTHRITIS; PROTO-ONCOGENE PROTEINS C-JUN; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; UP-REGULATION;

EID: 84899523181     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.1981     Document Type: Article

References (33)

1. Goldring MB and Goldring SR: Osteoarthritis. J Cell Physiol 213: 626-634, 2007. (Pubitemid 350058254)
2. Arden N and Nevitt MC: Osteoarthritis: epidemiology. Best Pract Res Clin Rheumatol 20: 3-25, 2006. (Pubitemid 43230460)
3. Hashimoto S, Ochs RL, Komiya S and Lotz M: Linkage of chondrocyte apoptosis and cartilage degradation in human osteoarthritis. Arthritis Rheum 41: 1632-1638, 1998. (Pubitemid 28459922)
4. Heraud F, Heraud A and Harmand MF: Apoptosis in normal and osteoarthritic human articular cartilage. Ann Rheum Dis 59: 959-965, 2000.
5. Kobayashi M, Squires GR, Mousa A, et al: Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage. Arthritis Rheum 52: 128-135, 2005. (Pubitemid 40129241)
6. Yasuhara R, Miyamoto Y, Akaike T, et al: Interleukin-1beta induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner. Biochem J 389: 315-323, 2005. (Pubitemid 41021134)
7. Lopez-Armada MJ, Carames B, Lires-Dean M, et al: Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes. Osteoarthritis Cartilage 14: 660-669, 2006. (Pubitemid 43869411)
8. Hagemeier K, Lurbke A, Hucke S, et al: Puma, but not noxa is essential for oligodendroglial cell death. Glia 61: 1712-1723, 2013.
9. Guadagno J, Xu X, Karajgikar M, Brown A and Cregan SP: Microglia-derived TNFalpha induces apoptosis in neural precursor cells via transcriptional activation of the Bcl-2 family member Puma. Cell Death Dis 4: e538, 2013.
10. Zheng X, He K, Zhang L and Yu J: Crizotinib induces PUMA-dependent apoptosis in colon cancer cells. Mol Cancer Ther 12: 777-786, 2013.
11. Reimertz C, Kogel D, Rami A, Chittenden T and Prehn JH: Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J Cell Biol 162: 587-597, 2003. (Pubitemid 37022937)
12. Zou CG, Cao XZ, Zhao YS, et al: The molecular mechanism of endoplasmic reticulum stress-induced apoptosis in PC-12 neuronal cells: the protective effect of insulin-like growth factor I. Endocrinology 150: 277-285, 2009.
13. Chang L and Karin M: Mammalian MAP kinase signalling cascades. Nature 410: 37-40, 2001. (Pubitemid 32225829)
14. Islam S, Kermode T, Sultana D, et al: Expression profile of protein tyrosine kinase genes in human osteoarthritis chondrocytes. Osteoarthritis Cartilage 9: 684-693, 2001. (Pubitemid 33076759)
15. Fan Z, Soder S, Oehler S, Fundel K and Aigner T: Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage. Am J Pathol 171: 938-946, 2007. (Pubitemid 47440992)
16. Mengshol JA, Vincenti MP, Coon CI, Barchowsky A and Brinckerhoff CE: Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. Arthritis Rheum 43: 801-811, 2000.
17. Newton R, Stevens DA, Hart LA, Lindsay M, Adcock IM and Barnes PJ: Superinduction of COX-2 mRNA by cycloheximide and interleukin-1beta involves increased transcription and correlates with increased NF-kappaB and JNK activation. FEBS Lett 418: 135-138, 1997. (Pubitemid 27514432)
18. Ray A, Shakya A and Ray BK: Inflammation-responsive transcription factors SAF-1 and c-Jun/c-Fos promote canine MMP-1 gene expression. Biochim Biophys Acta 1732: 53-61, 2005. (Pubitemid 43267304)
19. Ambacher KK, Pitzul KB, Karajgikar M, Hamilton A, Ferguson SS and Cregan SP: The JNK- and AKT/GSK3beta- signaling pathways converge to regulate Puma induction and neuronal apoptosis induced by trophic factor deprivation. PloS One 7: e46885, 2012.
20. Zhao Z, Wang J, Tang J, et al: JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells. Biochem J 444: 291-301, 2012.
21. Zamli Z and Sharif M: Chondrocyte apoptosis: a cause or consequence of osteoarthritis? Int J Rheum Dis 14: 159-166, 2011.
22. Carames B, Taniguchi N, Otsuki S, Blanco FJ and Lotz M: Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis. Arthritis Rheum 62: 791-801, 2010.
23. D'Lima D, Hermida J, Hashimoto S, Colwell C and Lotz M: Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis. Arthritis Rheum 54: 1814-1821, 2006. (Pubitemid 43877931)
24. Zemmyo M, Meharra EJ, Kuhn K, Creighton-Achermann L and Lotz M: Accelerated, aging-dependent development of osteoarthritis in alpha1 integrin-deficient mice. Arthritis Rheum 48: 2873-2880, 2003. (Pubitemid 37280616)
25. Mistry D, Oue Y, Chambers MG, Kayser MV and Mason RM: Chondrocyte death during murine osteoarthritis. Osteoarthritis Cartilage 12: 131-141, 2004. (Pubitemid 38181120)
26. Thomas CM, Fuller CJ, Whittles CE and Sharif M: Chondrocyte death by apoptosis is associated with cartilage matrix degradation. Osteoarthritis Cartilage 15: 27-34, 2007. (Pubitemid 46117914)
27. Blanco FJ, Guitian R, Vazquez-Martul E, de Toro FJ and Galdo F: Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology. Arthritis Rheum 41: 284-289, 1998. (Pubitemid 28087696)
28. Sharif M, Whitehouse A, Sharman P, Perry M and Adams M: Increased apoptosis in human osteoarthritic cartilage corresponds to reduced cell density and expression of caspase-3. Arthritis Rheum 50: 507-515, 2004. (Pubitemid 38198834)
29. Matsuo M, Nishida K, Yoshida A, Murakami T and Inoue H: Expression of caspase-3 and -9 relevant to cartilage destruction and chondrocyte apoptosis in human osteoarthritic cartilage. Acta Med Okayama 55: 333-340, 2001.
30. Kim HA, Lee YJ, Seong SC, Choe KW and Song YW: Apoptotic chondrocyte death in human osteoarthritis. J Rheumatol 27: 455-462, 2000. (Pubitemid 30095481)
31. Hashimoto S, Takahashi K, Amiel D, Coutts RD and Lotz M: Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis. Arthritis Rheum 41: 1266-1274, 1998. (Pubitemid 28313430)
32. Hashimoto S, Nishiyama T, Hayashi S, et al: Role of p53 in human chondrocyte apoptosis in response to shear strain. Arthritis Rheum 60: 2340-2349, 2009.
33. Aigner T, Hemmel M, Neureiter D, et al: Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage. Arthritis Rheum 44: 1304-1312, 2001. (Pubitemid 32537528)