메뉴 건너뛰기




Volumn 279, Issue 19, 2012, Pages 3652-3664

Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer

Author keywords

gastric cancer; growth; growth arrest specific gene 1 (GAS1); proliferation; tumorigenesis

Indexed keywords

CASPASE 3; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA;

EID: 84866372420     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2012.08726.x     Document Type: Article
Times cited : (33)

References (44)
  • 3
    • 0031874523 scopus 로고    scopus 로고
    • Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts
    • DOI 10.1006/excr.1998.4011
    • Evdokiou A, &, Cowled PA, (1998) Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts. Exp Cell Res 240, 359-367. (Pubitemid 28371117)
    • (1998) Experimental Cell Research , vol.240 , Issue.2 , pp. 359-367
    • Evdokiou, A.1    Cowled, P.A.2
  • 4
    • 0026758356 scopus 로고
    • The growth arrest-specific gene, gas1, is involved in growth suppression
    • Del Sal G, Ruaro ME, Philipson L, &, Schneider C, (1992) The growth arrest-specific gene, gas1, is involved in growth suppression. Cell 70, 595-607.
    • (1992) Cell , vol.70 , pp. 595-607
    • Del Sal, G.1    Ruaro, M.E.2    Philipson, L.3    Schneider, C.4
  • 6
    • 12244264781 scopus 로고    scopus 로고
    • Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis
    • DOI 10.1002/jnr.10461
    • Zamorano A, Lamas M, Vergara P, Naranjo JR, &, Segovia J, (2003) Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis. J Neurosci Res 71, 256-263. (Pubitemid 36055470)
    • (2003) Journal of Neuroscience Research , vol.71 , Issue.2 , pp. 256-263
    • Zamorano, A.1    Lamas, M.2    Vergara, P.3    Naranjo, J.R.4    Segovia, J.5
  • 7
    • 1842472001 scopus 로고    scopus 로고
    • Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo
    • DOI 10.1016/j.nbd.2003.11.022, PII S0969996103002596
    • Zamorano A, Mellstrom B, Vergara P, Naranjo JR, &, Segovia J, (2004) Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo. Neurobiol Dis 15, 483-491. (Pubitemid 38429963)
    • (2004) Neurobiology of Disease , vol.15 , Issue.3 , pp. 483-491
    • Zamorano, A.1    Mellstrom, B.2    Vergara, P.3    Naranjo, J.R.4    Segovia, J.5
  • 9
    • 79951575789 scopus 로고    scopus 로고
    • Down-regulated GAS1 expression correlates with recurrence in stage II and III colorectal cancer
    • Jiang Z, Xu Y, &, Cai S, (2011) Down-regulated GAS1 expression correlates with recurrence in stage II and III colorectal cancer. Hum Pathol 42, 361-368.
    • (2011) Hum Pathol , vol.42 , pp. 361-368
    • Jiang, Z.1    Xu, Y.2    Cai, S.3
  • 10
    • 55749101028 scopus 로고    scopus 로고
    • A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene
    • Gobeil S, Zhu X, Doillon CJ, &, Green MR, (2008) A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene. Genes Dev 22, 2932-2940.
    • (2008) Genes Dev , vol.22 , pp. 2932-2940
    • Gobeil, S.1    Zhu, X.2    Doillon, C.J.3    Green, M.R.4
  • 11
    • 11144355361 scopus 로고    scopus 로고
    • Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis
    • DOI 10.1182/blood-2003-07-2459
    • Spagnuolo R, Corada M, Orsenigo F, Zanetta L, Deuschle U, Sandy P, Schneider C, Drake CJ, Breviario F, &, Dejana E, (2004) Gas1 is induced by VE-cadherin and vascular endothelial growth factor and inhibits endothelial cell apoptosis. Blood 103, 3005-3012. (Pubitemid 38451673)
    • (2004) Blood , vol.103 , Issue.8 , pp. 3005-3012
    • Spagnuolo, R.1    Corada, M.2    Orsenigo, F.3    Zanetta, L.4    Deuschle, U.5    Sandy, P.6    Schneider, C.7    Drake, C.J.8    Breviario, F.9    Dejana, E.10
  • 13
    • 0037439019 scopus 로고    scopus 로고
    • Fragile sites and bladder cancer
    • DOI 10.1016/S0165-4608(02)00650-7, PII S0165460802006507
    • Moriarty HT, &, Webster LR, (2003) Fragile sites and bladder cancer. Cancer Genet Cytogenet 140, 89-98. (Pubitemid 36349007)
    • (2003) Cancer Genetics and Cytogenetics , vol.140 , Issue.2 , pp. 89-98
    • Moriarty, H.T.1    Webster, L.R.2
  • 14
    • 0024323196 scopus 로고
    • Involvement of bands 9q21-q22 in five cases of acute nonlymphocytic leukemia
    • DOI 10.1016/0165-4608(89)90229-X
    • Sreekantaiah C, Baer MR, Preisler HD, &, Sandberg AA, (1989) Involvement of bands 9q21-q22 in five cases of acute nonlymphocytic leukemia. Cancer Genet Cytogenet 39, 55-64. (Pubitemid 19169861)
    • (1989) Cancer Genetics and Cytogenetics , vol.39 , Issue.1 , pp. 55-64
    • Sreekantaiah, C.1    Baer, M.R.2    Preisler, H.D.3    Sandberg, A.A.4
  • 18
    • 70350400865 scopus 로고    scopus 로고
    • Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library
    • Zhao L, Pan Y, Gang Y, Wang H, Jin H, Tie J, Xia L, Zhang Y, He L, Yao L, et al. (2009) Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library. J Biol Chem 284, 26273-26285.
    • (2009) J Biol Chem , vol.284 , pp. 26273-26285
    • Zhao, L.1    Pan, Y.2    Gang, Y.3    Wang, H.4    Jin, H.5    Tie, J.6    Xia, L.7    Zhang, Y.8    He, L.9    Yao, L.10
  • 19
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • DOI 10.1038/35077213
    • Evan GI, &, Vousden KH, (2001) Proliferation, cell cycle and apoptosis in cancer. Nature 411, 342-348. (Pubitemid 32467043)
    • (2001) Nature , vol.411 , Issue.6835 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 20
  • 21
    • 10344222964 scopus 로고    scopus 로고
    • Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GAS1 and PTC mutations
    • Simoneau AR, Spruck CH III, Gonzalez-Zulueta M, Gonzalgo ML, Chan MF, Tsai YC, Dean M, Steven K, Horn T, &, Jones PA, (1996) Evidence for two tumor suppressor loci associated with proximal chromosome 9p to q and distal chromosome 9q in bladder cancer and the initial screening for GAS1 and PTC mutations. Cancer Res 56, 5039-5043. (Pubitemid 26374446)
    • (1996) Cancer Research , vol.56 , Issue.21 , pp. 5039-5043
    • Simoneau, A.R.1    Spruck III, C.H.2    Gonzalez-Zulueta, M.3    Gonzalgo, M.L.4    Chan, M.F.5    Tsai, Y.C.6    Dean, M.7    Steven, K.8    Horn, T.9    Jones, P.A.10
  • 22
    • 67349147868 scopus 로고    scopus 로고
    • Gas1 inhibits cell proliferation and induces apoptosis of human primary gliomas in the absence of Shh
    • Domínguez-Monzõn G, Benítez JA, Vergara P, Lorenzana R, &, Segovia J, (2009) Gas1 inhibits cell proliferation and induces apoptosis of human primary gliomas in the absence of Shh. Int J Dev Neurosci 27, 305-313.
    • (2009) Int J Dev Neurosci , vol.27 , pp. 305-313
    • Domínguez-Monzõn, G.1    Benítez, J.A.2    Vergara, P.3    Lorenzana, R.4    Segovia, J.5
  • 23
    • 0034057320 scopus 로고    scopus 로고
    • Apoptosis in cancer
    • Lowe SW, &, Lin AW, (2000) Apoptosis in cancer. Carcinogenesis 21, 485-495. (Pubitemid 30137934)
    • (2000) Carcinogenesis , vol.21 , Issue.3 , pp. 485-495
    • Lowe, S.W.1    Lin, A.W.2
  • 24
    • 84862495085 scopus 로고    scopus 로고
    • Gas1 induces cell death through an intrinsic apoptotic pathway
    • Zarco N, Gonzalez-Ramirez R, Gonzalez RO, &, Segovia J, (2012) Gas1 induces cell death through an intrinsic apoptotic pathway. Apoptosis 17, 627-635.
    • (2012) Apoptosis , vol.17 , pp. 627-635
    • Zarco, N.1    Gonzalez-Ramirez, R.2    Gonzalez, R.O.3    Segovia, J.4
  • 25
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux DL, Cory S, &, Adams JM, (1988) Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 335, 440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 26
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D, Nunez G, Milliman C, Schreiber RD, &, Korsmeyer SJ, (1990) Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348, 334-336. (Pubitemid 120029101)
    • (1990) Nature , vol.348 , Issue.6299 , pp. 334-336
    • Hockenbery, D.1    Ninez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 27
    • 44949249814 scopus 로고    scopus 로고
    • MiR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells
    • DOI 10.1002/ijc.23501
    • Xia L, Zhang D, Du R, Pan Y, Zhao L, Sun S, Hong L, Liu J, &, Fan D, (2008) miR-15b and miR-16 modulate multidrug resistance by targeting BCL2 in human gastric cancer cells. Int J Cancer 123, 372-379. (Pubitemid 351842022)
    • (2008) International Journal of Cancer , vol.123 , Issue.2 , pp. 372-379
    • Xia, L.1    Zhang, D.2    Du, R.3    Pan, Y.4    Zhao, L.5    Sun, S.6    Hong, L.7    Liu, J.8    Fan, D.9
  • 28
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • DOI 10.1126/science.275.5302.967
    • Rampino N, Yamamoto H, Ionov Y, Li Y, Sawai H, Reed JC, &, Perucho M, (1997) Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science 275, 967-969. (Pubitemid 27087710)
    • (1997) Science , vol.275 , Issue.5302 , pp. 967-969
    • Rampino, N.1    Yamamoto, H.2    Ionov, Y.3    Li, Y.4    Sawai, H.5    Reed, J.C.6    Perucho, M.7
  • 29
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programed cell death
    • DOI 10.1016/0092-8674(93)90509-O
    • Oltvai ZN, Milliman CL, &, Korsmeyer SJ, (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619. (Pubitemid 23259742)
    • (1993) Cell , vol.74 , Issue.4 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 30
    • 0032877668 scopus 로고    scopus 로고
    • Dysregulation of apoptosis in cancer
    • Reed JC, (1999) Dysregulation of apoptosis in cancer. J Clin Oncol 17, 2941-2953. (Pubitemid 29415256)
    • (1999) Journal of Clinical Oncology , vol.17 , Issue.9 , pp. 2941-2953
    • Reed, J.C.1
  • 32
    • 38849103854 scopus 로고    scopus 로고
    • A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax
    • DOI 10.1139/O07-141
    • Li X, Hong L, Zhao Y, Jin H, Fan R, Du R, Xia L, Luo G, &, Fan D, (2007) A new apoptosis inhibitor, CIAPIN1 (cytokine-induced apoptosis inhibitor 1), mediates multidrug resistance in leukemia cells by regulating MDR-1, Bcl-2, and Bax. Biochem Cell Biol 85, 741-750. (Pubitemid 351198421)
    • (2007) Biochemistry and Cell Biology , vol.85 , Issue.6 , pp. 741-750
    • Li, X.1    Hong, L.2    Zhao, Y.3    Jin, H.4    Fan, R.5    Du, R.6    Xia, L.7    Luo, G.8    Fan, D.9
  • 33
    • 0035942494 scopus 로고    scopus 로고
    • Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: A possible promotion mechanism for tumour growth
    • DOI 10.1038/sj.onc.1204422
    • Oehler MK, Norbury C, Hague S, Rees MC, &, Bicknell R, (2001) Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth. Oncogene 20, 2937-2945. (Pubitemid 33027761)
    • (2001) Oncogene , vol.20 , Issue.23 , pp. 2937-2945
    • Oehler, M.K.1    Norbury, C.2    Hague, S.3    Rees, M.C.P.4    Bicknell, R.5
  • 34
    • 0029888125 scopus 로고    scopus 로고
    • Overexpression of HER2 modulates bcl-2, Bcl-X(L) and tamoxifen induced apoptosis in human MCP-7 breast cancer cells
    • Kumar R, Mandal M, Lipton A, Harvey H, &, Thompson CB, (1996) Overexpression of HER2 modulates bcl-2, bcl-XL, and tamoxifen-induced apoptosis in human MCF-7 breast cancer cells. Clin Cancer Res 2, 1215-1219. (Pubitemid 26238454)
    • (1996) Clinical Cancer Research , vol.2 , Issue.7 , pp. 1215-1219
    • Kumar, R.1    Mandal, M.2    Lipton, A.3    Harvey, H.4    Thompson, C.B.5
  • 35
    • 0032589824 scopus 로고    scopus 로고
    • Bcl-x(L) and Bcl-2 expression in squamous cell carcinoma of the head and neck
    • DOI 10.1002/(SICI)1097-0142(19990101)85:1<164::AID-CNCR23>3.0.CO;2- Q
    • Pena JC, Thompson CB, Recant W, Vokes EE, &, Rudin CM, (1999) Bcl-xL and Bcl-2 expression in squamous cell carcinoma of the head and neck. Cancer 85, 164-170. (Pubitemid 29031371)
    • (1999) Cancer , vol.85 , Issue.1 , pp. 164-170
    • Pena, J.C.1    Thompson, C.B.2    Recant, W.3    Vokes, E.E.4    Rudin, C.M.5
  • 37
    • 34250839385 scopus 로고    scopus 로고
    • P75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells
    • DOI 10.1593/neo.07175
    • Jin H, Pan Y, Zhao L, Zhai H, Li X, Sun L, He L, Chen Y, Hong L, Du Y, et al. (2007) p75 neurotrophin receptor suppresses the proliferation of human gastric cancer cells. Neoplasia 9, 471-478. (Pubitemid 46983449)
    • (2007) Neoplasia , vol.9 , Issue.6 , pp. 471-478
    • Jin, H.1    Pan, Y.2    Zhao, L.3    Zhai, H.4    Li, X.5    Sun, L.6    He, L.7    Chen, Y.8    Hong, L.9    Du, Y.10    Fan, D.11
  • 38
    • 36849064813 scopus 로고    scopus 로고
    • The role of Gas1 in embryonic development and its implications for human disease
    • Martinelli DC, &, Fan CM, (2007) The role of Gas1 in embryonic development and its implications for human disease. Cell Cycle 6, 2650-2655. (Pubitemid 350224048)
    • (2007) Cell Cycle , vol.6 , Issue.21 , pp. 2650-2655
    • Martinelli, D.C.1    Fan, C.-M.2
  • 43
    • 77953552969 scopus 로고    scopus 로고
    • New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis
    • Wang Y, Gao J, Zhang D, Zhang J, Ma J, &, Jiang H, (2010) New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis. J Hepatol 53, 132-144.
    • (2010) J Hepatol , vol.53 , pp. 132-144
    • Wang, Y.1    Gao, J.2    Zhang, D.3    Zhang, J.4    Ma, J.5    Jiang, H.6
  • 44
    • 80054751348 scopus 로고    scopus 로고
    • Downregulation of RPL6 by siRNA inhibits proliferation and cell cycle progression of human gastric cancer cell lines
    • Wu Q, Gou Y, Wang Q, Jin H, Cui L, Zhang Y, He L, Wang J, Nie Y, Shi Y, et al. (2011) Downregulation of RPL6 by siRNA inhibits proliferation and cell cycle progression of human gastric cancer cell lines. PLoS One 6, e26401.
    • (2011) PLoS One , vol.6
    • Wu, Q.1    Gou, Y.2    Wang, Q.3    Jin, H.4    Cui, L.5    Zhang, Y.6    He, L.7    Wang, J.8    Nie, Y.9    Shi, Y.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.