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Volumn 83, Issue 2, 2013, Pages 251-263

Growth arrest-specific protein 1 is a novel endogenous inhibitor of glomerular cell activation and proliferation

Author keywords

mesangial cell; mesangioproliferative glomerulonephritis; proliferation; shedding

Indexed keywords

ADAM10 ENDOPEPTIDASE; CELL PROTEIN; CREATININE; GROWTH ARREST SPECIFIC PROTEIN 1; IMMUNOGLOBULIN FC FRAGMENT; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BB; PLATELET DERIVED GROWTH FACTOR CC; PLATELET DERIVED GROWTH FACTOR DD; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

EID: 84873406405     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2012.400     Document Type: Article
Times cited : (23)

References (43)
  • 1
    • 0035034653 scopus 로고    scopus 로고
    • Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis
    • Ostendorf T, Kunter U, Grone HJ et al. Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol 2001; 12: 909-918.
    • (2001) J Am Soc Nephrol , vol.12 , pp. 909-918
    • Ostendorf, T.1    Kunter, U.2    Grone, H.J.3
  • 2
    • 33645471300 scopus 로고    scopus 로고
    • Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis
    • Ostendorf T, Rong S, Boor P et al. Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol 2006; 17: 1054-1062.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1054-1062
    • Ostendorf, T.1    Rong, S.2    Boor, P.3
  • 3
    • 10744223785 scopus 로고    scopus 로고
    • A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis
    • Ostendorf T, van Roeyen CR, Peterson JD et al. A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis. J Am Soc Nephrol 2003; 14: 2237-2247.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2237-2247
    • Ostendorf, T.1    Van Roeyen, C.R.2    Peterson, J.D.3
  • 4
    • 37249021044 scopus 로고    scopus 로고
    • CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation
    • van Roeyen CR, Eitner F, Scholl T et al. CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation. Kidney Int 2008; 73: 86-94.
    • (2008) Kidney Int , vol.73 , pp. 86-94
    • Van Roeyen, C.R.1    Eitner, F.2    Scholl, T.3
  • 5
    • 0031874523 scopus 로고    scopus 로고
    • Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts
    • Evdokiou A, Cowled PA. Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts. Exp Cell Res 1998; 240: 359-367.
    • (1998) Exp Cell Res , vol.240 , pp. 359-367
    • Evdokiou, A.1    Cowled, P.A.2
  • 6
    • 0034666231 scopus 로고    scopus 로고
    • The growth suppressing gas1 product is a GPI-linked protein
    • Stebel M, Vatta P, Ruaro ME et al. The growth suppressing gas1 product is a GPI-linked protein. FEBS Lett 2000; 481: 152-158.
    • (2000) FEBS Lett , vol.481 , pp. 152-158
    • Stebel, M.1    Vatta, P.2    Ruaro, M.E.3
  • 7
    • 0028841560 scopus 로고
    • Gas1-induced growth suppression requires a transactivation-independent p53 function
    • Del Sal G, Ruaro EM, Utrera R et al. Gas1-induced growth suppression requires a transactivation-independent p53 function. Mol Cell Biol 1995; 15: 7152-7160.
    • (1995) Mol Cell Biol , vol.15 , pp. 7152-7160
    • Del Sal, G.1    Ruaro, E.M.2    Utrera, R.3
  • 8
    • 0026758356 scopus 로고
    • The growth arrest-specific gene, gas1, is involved in growth suppression
    • Del Sal G, Ruaro ME, Philipson L et al. The growth arrest-specific gene, gas1, is involved in growth suppression. Cell 1992; 70: 595-607.
    • (1992) Cell , vol.70 , pp. 595-607
    • Del Sal, G.1    Ruaro, M.E.2    Philipson, L.3
  • 9
    • 33744912010 scopus 로고    scopus 로고
    • Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling
    • Cabrera JR, Sanchez-Pulido L, Rojas AM et al. Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling. J Biol Chem 2006; 281: 14330-14339.
    • (2006) J Biol Chem , vol.281 , pp. 14330-14339
    • Cabrera, J.R.1    Sanchez-Pulido, L.2    Rojas, A.M.3
  • 10
    • 43049172139 scopus 로고    scopus 로고
    • Gas1 reduces Ret tyrosine 1062 phosphorylation and alters GDNF-mediated intracellular signaling
    • Lopez-Ramirez MA, Dominguez-Monzon G, Vergara P et al. Gas1 reduces Ret tyrosine 1062 phosphorylation and alters GDNF-mediated intracellular signaling. Int J Dev Neurosci 2008; 26: 497-503.
    • (2008) Int J Dev Neurosci , vol.26 , pp. 497-503
    • Lopez-Ramirez, M.A.1    Dominguez-Monzon, G.2    Vergara, P.3
  • 11
    • 34249904447 scopus 로고    scopus 로고
    • Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog
    • Seppala M, Depew MJ, Martinelli DC et al. Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog. J Clin Invest 2007; 117: 1575-1584.
    • (2007) J Clin Invest , vol.117 , pp. 1575-1584
    • Seppala, M.1    Depew, M.J.2    Martinelli, D.C.3
  • 12
    • 0035371206 scopus 로고    scopus 로고
    • Functions of the growth arrest specific 1 gene in the development of the mouse embryo
    • Lee KK, Leung AK, Tang MK et al. Functions of the growth arrest specific 1 gene in the development of the mouse embryo. Dev Biol 2001; 234: 188-203.
    • (2001) Dev Biol , vol.234 , pp. 188-203
    • Lee, K.K.1    Leung, A.K.2    Tang, M.K.3
  • 13
    • 50849113116 scopus 로고    scopus 로고
    • Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17
    • Esselens CW, Malapeira J, Colome N et al. Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17. Biol Chem 2008; 389: 1075-1084.
    • (2008) Biol Chem , vol.389 , pp. 1075-1084
    • Esselens, C.W.1    Malapeira, J.2    Colome, N.3
  • 14
    • 7444222501 scopus 로고    scopus 로고
    • GPI-anchored protein cleavage in the regulation of transmembrane signals
    • Sharom FJ, Radeva G. GPI-anchored protein cleavage in the regulation of transmembrane signals. Subcell Biochem 2004; 37: 285-315.
    • (2004) Subcell Biochem , vol.37 , pp. 285-315
    • Sharom, F.J.1    Radeva, G.2
  • 15
    • 69249128689 scopus 로고    scopus 로고
    • Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein
    • Taylor DR, Parkin ET, Cocklin SL et al. Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein. J Biol Chem 2009; 284: 22590-22600.
    • (2009) J Biol Chem , vol.284 , pp. 22590-22600
    • Taylor, D.R.1    Parkin, E.T.2    Cocklin, S.L.3
  • 16
    • 0042237924 scopus 로고    scopus 로고
    • The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
    • Hundhausen C, Misztela D, Berkhout TA et al. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 2003; 102: 1186-1195.
    • (2003) Blood , vol.102 , pp. 1186-1195
    • Hundhausen, C.1    Misztela, D.2    Berkhout, T.A.3
  • 17
    • 15244349837 scopus 로고    scopus 로고
    • Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules
    • Ludwig A, Hundhausen C, Lambert MH et al. Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. Comb Chem High Throughput Screen 2005; 8: 161-171.
    • (2005) Comb Chem High Throughput Screen , vol.8 , pp. 161-171
    • Ludwig, A.1    Hundhausen, C.2    Lambert, M.H.3
  • 18
    • 66549086638 scopus 로고    scopus 로고
    • Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases
    • Koenen RR, Pruessmeyer J, Soehnlein O et al. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood 2009; 113: 4799-4809.
    • (2009) Blood , vol.113 , pp. 4799-4809
    • Koenen, R.R.1    Pruessmeyer, J.2    Soehnlein, O.3
  • 19
    • 45149117638 scopus 로고    scopus 로고
    • ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin
    • Schulz B, Pruessmeyer J, Maretzky T et al. ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. Circ Res 2008; 102: 1192-1201.
    • (2008) Circ Res , vol.102 , pp. 1192-1201
    • Schulz, B.1    Pruessmeyer, J.2    Maretzky, T.3
  • 20
    • 0034666386 scopus 로고    scopus 로고
    • Analysis of the domain requirement in Gas1 growth suppressing activity
    • Ruaro ME, Stebel M, Vatta P et al. Analysis of the domain requirement in Gas1 growth suppressing activity. FEBS Lett 2000; 481: 159-163.
    • (2000) FEBS Lett , vol.481 , pp. 159-163
    • Ruaro, M.E.1    Stebel, M.2    Vatta, P.3
  • 21
    • 10244265941 scopus 로고    scopus 로고
    • Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis
    • Shankland SJ, Hugo C, Coats SR et al. Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis. Kidney Int 1996; 50: 1230-1239.
    • (1996) Kidney Int , vol.50 , pp. 1230-1239
    • Shankland, S.J.1    Hugo, C.2    Coats, S.R.3
  • 22
  • 23
    • 0030781307 scopus 로고    scopus 로고
    • Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist
    • Pippin JW, Qu Q, Meijer L et al. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist. J Clin Invest 1997; 100: 2512-2520.
    • (1997) J Clin Invest , vol.100 , pp. 2512-2520
    • Pippin, J.W.1    Qu, Q.2    Meijer, L.3
  • 24
    • 0033919485 scopus 로고    scopus 로고
    • Activation of PLC and PI 3 kinase by PDGF receptor alpha is not sufficient for mitogenesis and migration in mesangial cells
    • Choudhury GG, Grandaliano G, Jin DC et al. Activation of PLC and PI 3 kinase by PDGF receptor alpha is not sufficient for mitogenesis and migration in mesangial cells. Kidney Int 2000; 57: 908-917.
    • (2000) Kidney Int , vol.57 , pp. 908-917
    • Choudhury, G.G.1    Grandaliano, G.2    Jin, D.C.3
  • 25
    • 0026070076 scopus 로고
    • Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: Modulation and/or suppression by inflammatory cytokines
    • Floege J, Topley N, Hoppe J et al. Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines. Clin Exp Immunol 1991; 86: 334-341.
    • (1991) Clin Exp Immunol , vol.86 , pp. 334-341
    • Floege, J.1    Topley, N.2    Hoppe, J.3
  • 26
    • 0035949695 scopus 로고    scopus 로고
    • Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite
    • Lee CS, Buttitta L, Fan CM. Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite. Proc Natl Acad Sci USA 2001; 98: 11347-11352.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 11347-11352
    • Lee, C.S.1    Buttitta, L.2    Fan, C.M.3
  • 27
    • 3242884172 scopus 로고    scopus 로고
    • Restriction of sonic hedgehog signaling during early tooth development
    • Cobourne MT, Miletich I, Sharpe PT. Restriction of sonic hedgehog signaling during early tooth development. Development 2004; 131: 2875-2885.
    • (2004) Development , vol.131 , pp. 2875-2885
    • Cobourne, M.T.1    Miletich, I.2    Sharpe, P.T.3
  • 28
    • 0036434863 scopus 로고    scopus 로고
    • Platelet-derived growth factor-D expression in developing and mature human kidneys
    • Changsirikulchai S, Hudkins KL, Goodpaster TA et al. Platelet-derived growth factor-D expression in developing and mature human kidneys. Kidney Int 2002; 62: 2043-2054.
    • (2002) Kidney Int , vol.62 , pp. 2043-2054
    • Changsirikulchai, S.1    Hudkins, K.L.2    Goodpaster, T.A.3
  • 29
    • 82455212863 scopus 로고    scopus 로고
    • Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-d
    • van Roeyen CR, Eitner F, Boor P et al. Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D. Kidney Int 2011; 80: 1292-1305.
    • (2011) Kidney Int , vol.80 , pp. 1292-1305
    • Van Roeyen, C.R.1    Eitner, F.2    Boor, P.3
  • 30
    • 33645456580 scopus 로고    scopus 로고
    • Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival
    • Eremina V, Cui S, Gerber H et al. Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol 2006; 17: 724-735.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 724-735
    • Eremina, V.1    Cui, S.2    Gerber, H.3
  • 31
    • 0037119414 scopus 로고    scopus 로고
    • The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway
    • Sakamoto K, Yamaguchi S, Ando R et al. The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway. J Biol Chem 2002; 277: 29399-29405.
    • (2002) J Biol Chem , vol.277 , pp. 29399-29405
    • Sakamoto, K.1    Yamaguchi, S.2    Ando, R.3
  • 32
    • 0028925604 scopus 로고
    • The glycophosphatidylinositol anchor affects the conformation of Thy-1 protein
    • Barboni E, Rivero BP, George AJ et al. The glycophosphatidylinositol anchor affects the conformation of Thy-1 protein. J Cell Sci 1995; 108(Part 2): 487-497.
    • (1995) J Cell Sci , vol.108 , Issue.PART 2 , pp. 487-497
    • Barboni, E.1    Rivero, B.P.2    George, A.J.3
  • 33
    • 69449086668 scopus 로고    scopus 로고
    • ADAM17 upregulation in human renal disease: A role in modulating TGF-alpha availability?
    • Melenhorst WB, Visser L, Timmer A et al. ADAM17 upregulation in human renal disease: a role in modulating TGF-alpha availability? Am J Physiol Renal Physiol 2009; 297: F781-F790.
    • (2009) Am J Physiol Renal Physiol , vol.297
    • Melenhorst, W.B.1    Visser, L.2    Timmer, A.3
  • 34
    • 42249110692 scopus 로고    scopus 로고
    • The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells
    • Schramme A, Abdel-Bakky MS, Kampfer-Kolb N et al. The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells. Biochem Biophys Res Commun 2008; 370: 311-316.
    • (2008) Biochem Biophys Res Commun , vol.370 , pp. 311-316
    • Schramme, A.1    Abdel-Bakky, M.S.2    Kampfer-Kolb, N.3
  • 35
    • 1842472001 scopus 로고    scopus 로고
    • Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo
    • Zamorano A, Mellstrom B, Vergara P et al. Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo. Neurobiol Dis 2004; 15: 483-491.
    • (2004) Neurobiol Dis , vol.15 , pp. 483-491
    • Zamorano, A.1    Mellstrom, B.2    Vergara, P.3
  • 36
    • 0025277931 scopus 로고
    • Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells
    • Floege J, Topley N, Wessel K et al. Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells. Kidney Int 1990; 37: 859-869.
    • (1990) Kidney Int , vol.37 , pp. 859-869
    • Floege, J.1    Topley, N.2    Wessel, K.3
  • 37
    • 0036014940 scopus 로고    scopus 로고
    • Transcription factor Ets-1 regulates gelatinase a gene expression in mesangial cells
    • Reisdorff J, En-Nia A, Stefanidis I et al. Transcription factor Ets-1 regulates gelatinase a gene expression in mesangial cells. J Am Soc Nephrol 2002; 13: 1568-1578.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1568-1578
    • Reisdorff, J.1    En-Nia, A.2    Stefanidis, I.3
  • 38
    • 33646156419 scopus 로고    scopus 로고
    • Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells
    • van Roeyen CR, Ostendorf T, Denecke B et al. Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells. Kidney Int 2006; 69: 1393-1402.
    • (2006) Kidney Int , vol.69 , pp. 1393-1402
    • Van Roeyen, C.R.1    Ostendorf, T.2    Denecke, B.3
  • 39
    • 0036147231 scopus 로고    scopus 로고
    • Quantitative gene expression analysis in renal biopsies: A novel protocol for a high-throughput multicenter application
    • Cohen CD, Frach K, Schlondorff D et al. Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application. Kidney Int 2002; 61: 133-140.
    • (2002) Kidney Int , vol.61 , pp. 133-140
    • Cohen, C.D.1    Frach, K.2    Schlondorff, D.3
  • 40
    • 0025732353 scopus 로고
    • Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation
    • Johnson RJ, Iida H, Alpers CE et al. Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 1991; 87: 847-858.
    • (1991) J Clin Invest , vol.87 , pp. 847-858
    • Johnson, R.J.1    Iida, H.2    Alpers, C.E.3
  • 41
    • 84860235408 scopus 로고    scopus 로고
    • A novel, dual role of CCN3 in experimental glomerulonephritis: Pro-angiogenic and antimesangioproliferative effects
    • van Roeyen CR, Boor P, Borkham-Kamphorst E et al. A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects. Am J Pathol 2012; 180: 1979-1990.
    • (2012) Am J Pathol , vol.180 , pp. 1979-1990
    • Van Roeyen, C.R.1    Boor, P.2    Borkham-Kamphorst, E.3
  • 42
    • 0036208983 scopus 로고    scopus 로고
    • Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney
    • Eitner F, Ostendorf T, Van Roeyen C et al. Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney. J Am Soc Nephrol 2002; 13: 910-917.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 910-917
    • Eitner, F.1    Ostendorf, T.2    Van Roeyen, C.3
  • 43
    • 0032896149 scopus 로고    scopus 로고
    • Novel approach to specific growth factor inhibition in vivo: Antagonism of platelet-derived growth factor in glomerulonephritis by aptamers
    • Floege J, Ostendorf T, Janssen U et al. Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers. Am J Pathol 1999; 154: 169-179.
    • (1999) Am J Pathol , vol.154 , pp. 169-179
    • Floege, J.1    Ostendorf, T.2    Janssen, U.3


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