-
1
-
-
0035034653
-
Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis
-
Ostendorf T, Kunter U, Grone HJ et al. Specific antagonism of PDGF prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol 2001; 12: 909-918.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 909-918
-
-
Ostendorf, T.1
Kunter, U.2
Grone, H.J.3
-
2
-
-
33645471300
-
Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis
-
Ostendorf T, Rong S, Boor P et al. Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. J Am Soc Nephrol 2006; 17: 1054-1062.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1054-1062
-
-
Ostendorf, T.1
Rong, S.2
Boor, P.3
-
3
-
-
10744223785
-
A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis
-
Ostendorf T, van Roeyen CR, Peterson JD et al. A fully human monoclonal antibody (CR002) identifies PDGF-D as a novel mediator of mesangioproliferative glomerulonephritis. J Am Soc Nephrol 2003; 14: 2237-2247.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2237-2247
-
-
Ostendorf, T.1
Van Roeyen, C.R.2
Peterson, J.D.3
-
4
-
-
37249021044
-
CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation
-
van Roeyen CR, Eitner F, Scholl T et al. CCN3 is a novel endogenous PDGF-regulated inhibitor of glomerular cell proliferation. Kidney Int 2008; 73: 86-94.
-
(2008)
Kidney Int
, vol.73
, pp. 86-94
-
-
Van Roeyen, C.R.1
Eitner, F.2
Scholl, T.3
-
5
-
-
0031874523
-
Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts
-
Evdokiou A, Cowled PA. Growth-regulatory activity of the growth arrest-specific gene, GAS1, in NIH3T3 fibroblasts. Exp Cell Res 1998; 240: 359-367.
-
(1998)
Exp Cell Res
, vol.240
, pp. 359-367
-
-
Evdokiou, A.1
Cowled, P.A.2
-
6
-
-
0034666231
-
The growth suppressing gas1 product is a GPI-linked protein
-
Stebel M, Vatta P, Ruaro ME et al. The growth suppressing gas1 product is a GPI-linked protein. FEBS Lett 2000; 481: 152-158.
-
(2000)
FEBS Lett
, vol.481
, pp. 152-158
-
-
Stebel, M.1
Vatta, P.2
Ruaro, M.E.3
-
7
-
-
0028841560
-
Gas1-induced growth suppression requires a transactivation-independent p53 function
-
Del Sal G, Ruaro EM, Utrera R et al. Gas1-induced growth suppression requires a transactivation-independent p53 function. Mol Cell Biol 1995; 15: 7152-7160.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 7152-7160
-
-
Del Sal, G.1
Ruaro, E.M.2
Utrera, R.3
-
8
-
-
0026758356
-
The growth arrest-specific gene, gas1, is involved in growth suppression
-
Del Sal G, Ruaro ME, Philipson L et al. The growth arrest-specific gene, gas1, is involved in growth suppression. Cell 1992; 70: 595-607.
-
(1992)
Cell
, vol.70
, pp. 595-607
-
-
Del Sal, G.1
Ruaro, M.E.2
Philipson, L.3
-
9
-
-
33744912010
-
Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling
-
Cabrera JR, Sanchez-Pulido L, Rojas AM et al. Gas1 is related to the glial cell-derived neurotrophic factor family receptors alpha and regulates Ret signaling. J Biol Chem 2006; 281: 14330-14339.
-
(2006)
J Biol Chem
, vol.281
, pp. 14330-14339
-
-
Cabrera, J.R.1
Sanchez-Pulido, L.2
Rojas, A.M.3
-
10
-
-
43049172139
-
Gas1 reduces Ret tyrosine 1062 phosphorylation and alters GDNF-mediated intracellular signaling
-
Lopez-Ramirez MA, Dominguez-Monzon G, Vergara P et al. Gas1 reduces Ret tyrosine 1062 phosphorylation and alters GDNF-mediated intracellular signaling. Int J Dev Neurosci 2008; 26: 497-503.
-
(2008)
Int J Dev Neurosci
, vol.26
, pp. 497-503
-
-
Lopez-Ramirez, M.A.1
Dominguez-Monzon, G.2
Vergara, P.3
-
11
-
-
34249904447
-
Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog
-
Seppala M, Depew MJ, Martinelli DC et al. Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog. J Clin Invest 2007; 117: 1575-1584.
-
(2007)
J Clin Invest
, vol.117
, pp. 1575-1584
-
-
Seppala, M.1
Depew, M.J.2
Martinelli, D.C.3
-
12
-
-
0035371206
-
Functions of the growth arrest specific 1 gene in the development of the mouse embryo
-
Lee KK, Leung AK, Tang MK et al. Functions of the growth arrest specific 1 gene in the development of the mouse embryo. Dev Biol 2001; 234: 188-203.
-
(2001)
Dev Biol
, vol.234
, pp. 188-203
-
-
Lee, K.K.1
Leung, A.K.2
Tang, M.K.3
-
13
-
-
50849113116
-
Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17
-
Esselens CW, Malapeira J, Colome N et al. Metastasis-associated C4.4A, a GPI-anchored protein cleaved by ADAM10 and ADAM17. Biol Chem 2008; 389: 1075-1084.
-
(2008)
Biol Chem
, vol.389
, pp. 1075-1084
-
-
Esselens, C.W.1
Malapeira, J.2
Colome, N.3
-
14
-
-
7444222501
-
GPI-anchored protein cleavage in the regulation of transmembrane signals
-
Sharom FJ, Radeva G. GPI-anchored protein cleavage in the regulation of transmembrane signals. Subcell Biochem 2004; 37: 285-315.
-
(2004)
Subcell Biochem
, vol.37
, pp. 285-315
-
-
Sharom, F.J.1
Radeva, G.2
-
15
-
-
69249128689
-
Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein
-
Taylor DR, Parkin ET, Cocklin SL et al. Role of ADAMs in the ectodomain shedding and conformational conversion of the prion protein. J Biol Chem 2009; 284: 22590-22600.
-
(2009)
J Biol Chem
, vol.284
, pp. 22590-22600
-
-
Taylor, D.R.1
Parkin, E.T.2
Cocklin, S.L.3
-
16
-
-
0042237924
-
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion
-
Hundhausen C, Misztela D, Berkhout TA et al. The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion. Blood 2003; 102: 1186-1195.
-
(2003)
Blood
, vol.102
, pp. 1186-1195
-
-
Hundhausen, C.1
Misztela, D.2
Berkhout, T.A.3
-
17
-
-
15244349837
-
Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules
-
Ludwig A, Hundhausen C, Lambert MH et al. Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. Comb Chem High Throughput Screen 2005; 8: 161-171.
-
(2005)
Comb Chem High Throughput Screen
, vol.8
, pp. 161-171
-
-
Ludwig, A.1
Hundhausen, C.2
Lambert, M.H.3
-
18
-
-
66549086638
-
Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases
-
Koenen RR, Pruessmeyer J, Soehnlein O et al. Regulated release and functional modulation of junctional adhesion molecule A by disintegrin metalloproteinases. Blood 2009; 113: 4799-4809.
-
(2009)
Blood
, vol.113
, pp. 4799-4809
-
-
Koenen, R.R.1
Pruessmeyer, J.2
Soehnlein, O.3
-
19
-
-
45149117638
-
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin
-
Schulz B, Pruessmeyer J, Maretzky T et al. ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin. Circ Res 2008; 102: 1192-1201.
-
(2008)
Circ Res
, vol.102
, pp. 1192-1201
-
-
Schulz, B.1
Pruessmeyer, J.2
Maretzky, T.3
-
20
-
-
0034666386
-
Analysis of the domain requirement in Gas1 growth suppressing activity
-
Ruaro ME, Stebel M, Vatta P et al. Analysis of the domain requirement in Gas1 growth suppressing activity. FEBS Lett 2000; 481: 159-163.
-
(2000)
FEBS Lett
, vol.481
, pp. 159-163
-
-
Ruaro, M.E.1
Stebel, M.2
Vatta, P.3
-
21
-
-
10244265941
-
Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis
-
Shankland SJ, Hugo C, Coats SR et al. Changes in cell-cycle protein expression during experimental mesangial proliferative glomerulonephritis. Kidney Int 1996; 50: 1230-1239.
-
(1996)
Kidney Int
, vol.50
, pp. 1230-1239
-
-
Shankland, S.J.1
Hugo, C.2
Coats, S.R.3
-
23
-
-
0030781307
-
Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist
-
Pippin JW, Qu Q, Meijer L et al. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist. J Clin Invest 1997; 100: 2512-2520.
-
(1997)
J Clin Invest
, vol.100
, pp. 2512-2520
-
-
Pippin, J.W.1
Qu, Q.2
Meijer, L.3
-
24
-
-
0033919485
-
Activation of PLC and PI 3 kinase by PDGF receptor alpha is not sufficient for mitogenesis and migration in mesangial cells
-
Choudhury GG, Grandaliano G, Jin DC et al. Activation of PLC and PI 3 kinase by PDGF receptor alpha is not sufficient for mitogenesis and migration in mesangial cells. Kidney Int 2000; 57: 908-917.
-
(2000)
Kidney Int
, vol.57
, pp. 908-917
-
-
Choudhury, G.G.1
Grandaliano, G.2
Jin, D.C.3
-
25
-
-
0026070076
-
Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: Modulation and/or suppression by inflammatory cytokines
-
Floege J, Topley N, Hoppe J et al. Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines. Clin Exp Immunol 1991; 86: 334-341.
-
(1991)
Clin Exp Immunol
, vol.86
, pp. 334-341
-
-
Floege, J.1
Topley, N.2
Hoppe, J.3
-
26
-
-
0035949695
-
Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite
-
Lee CS, Buttitta L, Fan CM. Evidence that the WNT-inducible growth arrest-specific gene 1 encodes an antagonist of sonic hedgehog signaling in the somite. Proc Natl Acad Sci USA 2001; 98: 11347-11352.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 11347-11352
-
-
Lee, C.S.1
Buttitta, L.2
Fan, C.M.3
-
27
-
-
3242884172
-
Restriction of sonic hedgehog signaling during early tooth development
-
Cobourne MT, Miletich I, Sharpe PT. Restriction of sonic hedgehog signaling during early tooth development. Development 2004; 131: 2875-2885.
-
(2004)
Development
, vol.131
, pp. 2875-2885
-
-
Cobourne, M.T.1
Miletich, I.2
Sharpe, P.T.3
-
28
-
-
0036434863
-
Platelet-derived growth factor-D expression in developing and mature human kidneys
-
Changsirikulchai S, Hudkins KL, Goodpaster TA et al. Platelet-derived growth factor-D expression in developing and mature human kidneys. Kidney Int 2002; 62: 2043-2054.
-
(2002)
Kidney Int
, vol.62
, pp. 2043-2054
-
-
Changsirikulchai, S.1
Hudkins, K.L.2
Goodpaster, T.A.3
-
29
-
-
82455212863
-
Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-d
-
van Roeyen CR, Eitner F, Boor P et al. Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D. Kidney Int 2011; 80: 1292-1305.
-
(2011)
Kidney Int
, vol.80
, pp. 1292-1305
-
-
Van Roeyen, C.R.1
Eitner, F.2
Boor, P.3
-
30
-
-
33645456580
-
Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival
-
Eremina V, Cui S, Gerber H et al. Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. J Am Soc Nephrol 2006; 17: 724-735.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 724-735
-
-
Eremina, V.1
Cui, S.2
Gerber, H.3
-
31
-
-
0037119414
-
The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway
-
Sakamoto K, Yamaguchi S, Ando R et al. The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway. J Biol Chem 2002; 277: 29399-29405.
-
(2002)
J Biol Chem
, vol.277
, pp. 29399-29405
-
-
Sakamoto, K.1
Yamaguchi, S.2
Ando, R.3
-
32
-
-
0028925604
-
The glycophosphatidylinositol anchor affects the conformation of Thy-1 protein
-
Barboni E, Rivero BP, George AJ et al. The glycophosphatidylinositol anchor affects the conformation of Thy-1 protein. J Cell Sci 1995; 108(Part 2): 487-497.
-
(1995)
J Cell Sci
, vol.108
, Issue.PART 2
, pp. 487-497
-
-
Barboni, E.1
Rivero, B.P.2
George, A.J.3
-
33
-
-
69449086668
-
ADAM17 upregulation in human renal disease: A role in modulating TGF-alpha availability?
-
Melenhorst WB, Visser L, Timmer A et al. ADAM17 upregulation in human renal disease: a role in modulating TGF-alpha availability? Am J Physiol Renal Physiol 2009; 297: F781-F790.
-
(2009)
Am J Physiol Renal Physiol
, vol.297
-
-
Melenhorst, W.B.1
Visser, L.2
Timmer, A.3
-
34
-
-
42249110692
-
The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells
-
Schramme A, Abdel-Bakky MS, Kampfer-Kolb N et al. The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells. Biochem Biophys Res Commun 2008; 370: 311-316.
-
(2008)
Biochem Biophys Res Commun
, vol.370
, pp. 311-316
-
-
Schramme, A.1
Abdel-Bakky, M.S.2
Kampfer-Kolb, N.3
-
35
-
-
1842472001
-
Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo
-
Zamorano A, Mellstrom B, Vergara P et al. Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo. Neurobiol Dis 2004; 15: 483-491.
-
(2004)
Neurobiol Dis
, vol.15
, pp. 483-491
-
-
Zamorano, A.1
Mellstrom, B.2
Vergara, P.3
-
36
-
-
0025277931
-
Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells
-
Floege J, Topley N, Wessel K et al. Monokines and platelet-derived growth factor modulate prostanoid production in growth arrested, human mesangial cells. Kidney Int 1990; 37: 859-869.
-
(1990)
Kidney Int
, vol.37
, pp. 859-869
-
-
Floege, J.1
Topley, N.2
Wessel, K.3
-
37
-
-
0036014940
-
Transcription factor Ets-1 regulates gelatinase a gene expression in mesangial cells
-
Reisdorff J, En-Nia A, Stefanidis I et al. Transcription factor Ets-1 regulates gelatinase a gene expression in mesangial cells. J Am Soc Nephrol 2002; 13: 1568-1578.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1568-1578
-
-
Reisdorff, J.1
En-Nia, A.2
Stefanidis, I.3
-
38
-
-
33646156419
-
Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells
-
van Roeyen CR, Ostendorf T, Denecke B et al. Biological responses to PDGF-BB versus PDGF-DD in human mesangial cells. Kidney Int 2006; 69: 1393-1402.
-
(2006)
Kidney Int
, vol.69
, pp. 1393-1402
-
-
Van Roeyen, C.R.1
Ostendorf, T.2
Denecke, B.3
-
39
-
-
0036147231
-
Quantitative gene expression analysis in renal biopsies: A novel protocol for a high-throughput multicenter application
-
Cohen CD, Frach K, Schlondorff D et al. Quantitative gene expression analysis in renal biopsies: a novel protocol for a high-throughput multicenter application. Kidney Int 2002; 61: 133-140.
-
(2002)
Kidney Int
, vol.61
, pp. 133-140
-
-
Cohen, C.D.1
Frach, K.2
Schlondorff, D.3
-
40
-
-
0025732353
-
Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation
-
Johnson RJ, Iida H, Alpers CE et al. Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest 1991; 87: 847-858.
-
(1991)
J Clin Invest
, vol.87
, pp. 847-858
-
-
Johnson, R.J.1
Iida, H.2
Alpers, C.E.3
-
41
-
-
84860235408
-
A novel, dual role of CCN3 in experimental glomerulonephritis: Pro-angiogenic and antimesangioproliferative effects
-
van Roeyen CR, Boor P, Borkham-Kamphorst E et al. A novel, dual role of CCN3 in experimental glomerulonephritis: pro-angiogenic and antimesangioproliferative effects. Am J Pathol 2012; 180: 1979-1990.
-
(2012)
Am J Pathol
, vol.180
, pp. 1979-1990
-
-
Van Roeyen, C.R.1
Boor, P.2
Borkham-Kamphorst, E.3
-
42
-
-
0036208983
-
Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney
-
Eitner F, Ostendorf T, Van Roeyen C et al. Expression of a novel PDGF isoform, PDGF-C, in normal and diseased rat kidney. J Am Soc Nephrol 2002; 13: 910-917.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 910-917
-
-
Eitner, F.1
Ostendorf, T.2
Van Roeyen, C.3
-
43
-
-
0032896149
-
Novel approach to specific growth factor inhibition in vivo: Antagonism of platelet-derived growth factor in glomerulonephritis by aptamers
-
Floege J, Ostendorf T, Janssen U et al. Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers. Am J Pathol 1999; 154: 169-179.
-
(1999)
Am J Pathol
, vol.154
, pp. 169-179
-
-
Floege, J.1
Ostendorf, T.2
Janssen, U.3
|