Pontin is required for pre-TCR signaling at the β-selection checkpoint in T cell development

Biochemical and Biophysical Research Communications

Volumn 447, Issue 1, 2014, Pages 44-50

  Boo, Kyungjin ^a   Baek, Sung Hee ^a   Lee, Ho ^b  

^a Seoul National University   (South Korea)

^b National Cancer Center   (South Korea)

Author keywords

Notch; p53; Pontin; T cell development; Selection checkpoint

Indexed keywords

NOTCH RECEPTOR; PONTIN; PROTEIN P53; REGULATOR PROTEIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BETA SELECTION CHECKPOINT; CELL CYCLE CHECKPOINT; CELL MATURATION; CELL POPULATION; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; LOXP SITE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; WILD TYPE;

MUS;

NOTCH; P53; PONTIN; T CELL DEVELOPMENT; Β-SELECTION CHECKPOINT;

ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL DIFFERENTIATION; DNA HELICASES; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84899493267     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.03.092     Document Type: Article

References (35)

1. E.S. David-Fung, M.A. Yui, M. Morales, H. Wang, T. Taghon, R.A. Diamond, and E.V. Rothenberg Progression of regulatory gene expression states in fetal and adult pro-T-cell development Immunol. Rev. 209 2006 212 236
2. D.L. Wiest, M.A. Berger, and M. Carleton Control of early thymocyte development by the pre-T cell receptor complex: A receptor without a ligand? Semin. Immunol. 11 1999 251 262
3. M. Ciofani, and J.C. Zuniga-Pflucker A survival guide to early T cell development Immunol. Res. 34 2006 117 132
4. M.A. Bogue, C.M. Zhu, E. AguilarCordova, L.A. Donehower, and D.B. Roth p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes Genes Dev. 10 1996 553 565
5. C.J. Guidos, C.J. Williams, I. Grandal, G. Knowles, M.T.F. Huang, and J.S. Danska V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors Genes Dev. 10 1996 2038 2054
6. J.A. Di, M.J. Lenardo, and J.C. ZunigaPflucker p53 prevents maturation to the CD4(+)CD8(+) stage of thymocyte differentiation in the absence of T cell receptor rearrangement J. Exp. Med. 183 1996 1923 1928
7. P.S. Costello, S.C. Cleverley, R. Galandrini, S.W. Henning, and D.A. Cantrell The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis J. Exp. Med. 192 2000 77 85
8. M.C. Haks, P. Krimpenfort, J.H.N. van den Brakel, and A.M. Kruisbeek Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells Immunity 11 1999 91 101
9. S.J. Anderson, J.P.H. Lauritsen, M.G. Hartman, A.M.D. Foushee, J.M. Lefebvre, S.A. Shinton, B. Gerhardt, R.R. Hardy, T. Oravecz, and D.L. Wiest Ablation of ribosomal protein L22 selectively impairs alpha beta T cell development by activation of a p53-dependent checkpoint Immunity 26 2007 759 772
10. S.H. Baek When ATPases pontin and reptin met telomerase Dev. Cell 14 2008 459 461
11. P. Gallant Control of transcription by pontin and reptin Trends Cell Biol. 17 2007 187 192
12. S. Jha, and A. Dutta RVB1/RVB2: running rings around molecular biology Mol. Cell 34 2009 521 533
13. Y. Feng, N. Lee, and E.R. Fearon TIP49 regulates beta-catenin-mediated neoplastic transformation and T-cell factor target gene induction via effects on chromatin remodeling Cancer Res. 63 2003 8726 8734
14. O. Huber, L. Menard, V. Haurie, A. Nicou, D. Taras, and J. Rosenbaum Pontin and reptin, two related ATPases with multiple roles in cancer Cancer Res. 68 2008 6873 6876
15. J.H. Kim, J.M. Lee, H.J. Nam, H.J. Choi, J.W. Yang, J.S. Lee, M.H. Kim, S.I. Kim, C.H. Chung, K.I. Kim, and S.H. Baek SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells Proc. Natl. Acad. Sci. USA 104 2007 20793 20798
16. K. Taniue, T. Oda, T. Hayashi, M. Okuno, and T. Akiyama A member of the ETS family, EHF, and the ATPase RUVBL1 inhibit p53-mediated apoptosis EMBO Rep. 12 2011 682 689
17. M. Oukka, I.C. Ho, F.C. de la Brousse, T. Hoey, M.J. Grusby, and L.H. Glimcher The transcription factor NFAT4 is involved in the generation and survival of T cells Immunity 9 1998 295 304
18. A.M. Ranger, M.R. Hodge, E.M. Gravallese, M. Oukka, L. Davidson, F.W. Alt, F.C. de la Brousse, T. Hoey, M. Grusby, and L.H. Glimcher Delayed lymphoid repopulation with defects in IL-4-driven responses produced by inactivation of NF-ATc Immunity 8 1998 125 134
19. H. Yoshida, H. Nishina, H. Takimoto, L.E.M. Marengere, A.C. Wakeham, D. Bouchard, Y.Y. Kong, T. Ohteki, A. Shahinian, M. Bachmann, P.S. Ohashi, J.M. Penninger, G.R. Crabtree, and T.W. Mak The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production Immunity 8 1998 115 124
20. R.E. Voll, E. Jimi, R.J. Phillips, D.F. Barber, M. Rincon, A.C. Hayday, R.A. Flavell, and S. Ghosh NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development Immunity 13 2000 677 689
21. 2+ mobilization and activation of NF-kappa B and NFAT Nat. Immunol. 2 2001 403 409
22. J.R. Neilson, M.M. Winslow, E.M. Hur, and G.R. Crabtree Calcineurin B1 is essential for positive but not negative selection during thymocyte development Immunity 20 2004 255 266
23. K. Cante-Barrett, M.M. Winslow, and G.R. Crabtree Selective role of NFATc3 in positive selection of thymocytes J. Immunol. 179 2007 103 110
24. E.K. Koltsova, M. Ciofani, R. Benezra, T. Miyazaki, N. Clipstone, J.C. Zuniga-Pflucker, and D.L. Wiest Early growth response 1 and NF-ATc1 act in concert to promote thymocyte development beyond the beta-selection checkpoint J. Immunol. 179 2007 4694 4703
25. R. Berga-Bolanos, M. Alberdi, M. Buxade, J. Aramburu, and C. Lopez-Rodriguez NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte development Proc. Natl. Acad. Sci. USA 110 2013 16091 16096
26. Y. Yashiro-Ohtani, Y.P. He, T. Ohtani, M.E. Jones, O. Shestova, L.W. Xu, T.C. Fang, M.Y. Chiang, A.M. Intlekofer, S.C. Blacklow, Y. Zhuang, and W.S. Pear Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A Genes Dev. 23 2009 1665 1676
27. D.J. Izon, J.C. Aster, Y.P. He, A. Weng, F.G. Karnell, V. Patriub, L.W. Xu, S. Bakkour, C. Rodriguez, D. Allman, and W.S. Pear Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1 Immunity 16 2002 231 243
28. X.Y. Li, F. Gounari, A. Protopopov, K. Khazaie, and H. von Boehmer Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular Notch1 J. Exp. Med. 205 2008 2851 U2872
29. M.L. Deftos, E. Huang, E.W. Ojala, K.A. Forbush, and M.J. Bevan Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes Immunity 13 2000 73 84
30. B.J. Fowlkes, and E.A. Robey A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development J. Immunol. 169 2002 1817 1821
31. A.G. Pajerowski, C. Nguyen, H. Aghajanian, M.J. Shapiro, and V.S. Shapiro NKAP Is a transcriptional repressor of Notch signaling and is required for T cell development Immunity 30 2009 696 707
32. M. Dose, I. Khan, Z.Y. Guo, D. Kovalovsky, A. Krueger, H. von Boehmer, K. Khazaie, and F. Gounari C-Myc mediates pre-TCR-induced proliferation but not developmental progression Blood 108 2006 2669 2677
33. N.C. Douglas, H. Jacobs, A.L.M. Bothwell, and A.C. Hayday Defining the specific physiological requirements for c-Myc in T cell development Nat. Immunol. 2 2001 307 315
34. I. Saba, C. Kosan, L. Vassen, L. Klein-Hitpass, and T. Moroy Miz-1 is required to coordinate the expression of TCR beta and p53 effector genes at the pre-TCR "beta-selection" checkpoint J. Immunol. 187 2011 2982 2992
35. T. Taghon, M.A. Yui, R. Pant, R.A. Diamond, and E.V. Rothenberg Developmental and molecular characterization of emerging beta- and gamma delta-selected pre-T cells in the adult mouse thymus Immunity 24 2006 53 64