메뉴 건너뛰기




Volumn 13, Issue 1, 2014, Pages

MiR-375 activates p21 and suppresses telomerase activity by coordinately regulating HPV E6/E7, E6AP, CIP2A, and 14-3-3ζ

Author keywords

E6AP; Human papillomavirus; MicroRNA; miR 375; p21; Telomerase

Indexed keywords

CELL PROTEIN; CIP2A PROTEIN; E6 ASSOCIATED PROTEIN; MICRORNA 375; MYC PROTEIN; PROTEIN 14 3 3; PROTEIN E6; PROTEIN E7; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; TELOMERASE; TELOMERASE REVERSE TRANSCRIPTASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; AUTOANTIGEN; DNA BINDING PROTEIN; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 16; E6 PROTEIN, HUMAN PAPILLOMAVIRUS TYPE 18; KIAA1524 PROTEIN, HUMAN; MEMBRANE PROTEIN; MICRORNA; MIRN375 MICRORNA, HUMAN; ONCOGENE PROTEIN E7, HUMAN PAPILLOMAVIRUS TYPE 16; ONCOPROTEIN; REPRESSOR PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UBE3A PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

EID: 84899487649     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-80     Document Type: Article
Times cited : (84)

References (91)
  • 1
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • 10.1016/j.cell.2009.01.002, 3794896, 19167326
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233. 10.1016/j.cell.2009.01.002, 3794896, 19167326.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 2
    • 84859067415 scopus 로고    scopus 로고
    • Functional microRNA targets in protein coding sequences
    • 10.1093/bioinformatics/bts043, 22285563
    • Reczko M, Maragkakis M, Alexiou P, Grosse I, Hatzigeorgiou AG. Functional microRNA targets in protein coding sequences. Bioinformatics 2012, 28:771-776. 10.1093/bioinformatics/bts043, 22285563.
    • (2012) Bioinformatics , vol.28 , pp. 771-776
    • Reczko, M.1    Maragkakis, M.2    Alexiou, P.3    Grosse, I.4    Hatzigeorgiou, A.G.5
  • 3
    • 84878682019 scopus 로고    scopus 로고
    • Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions
    • 10.1091/mbc.E12-12-0891, 3667718, 23552692
    • Jung HM, Patel RS, Phillips BL, Wang H, Cohen DM, Reinhold WC, Chang LJ, Yang LJ, Chan EK. Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interactions. Mol Biol Cell 2013, 24:1638-1648. 10.1091/mbc.E12-12-0891, 3667718, 23552692.
    • (2013) Mol Biol Cell , vol.24 , pp. 1638-1648
    • Jung, H.M.1    Patel, R.S.2    Phillips, B.L.3    Wang, H.4    Cohen, D.M.5    Reinhold, W.C.6    Chang, L.J.7    Yang, L.J.8    Chan, E.K.9
  • 4
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • 2612969, 18955434
    • Friedman RC, Farh KK, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009, 19:92-105. 2612969, 18955434.
    • (2009) Genome Res , vol.19 , pp. 92-105
    • Friedman, R.C.1    Farh, K.K.2    Burge, C.B.3    Bartel, D.P.4
  • 5
    • 0027985695 scopus 로고
    • Human papillomaviruses
    • 10.1146/annurev.mi.48.100194.002235, 7826013
    • zur Hausen H, de Villiers EM. Human papillomaviruses. Annu Rev Microbiol 1994, 48:427-447. 10.1146/annurev.mi.48.100194.002235, 7826013.
    • (1994) Annu Rev Microbiol , vol.48 , pp. 427-447
    • zur Hausen, H.1    de Villiers, E.M.2
  • 6
    • 56449114183 scopus 로고    scopus 로고
    • HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women
    • 10.1002/cncr.23764, 18980286
    • Gillison ML, Chaturvedi AK, Lowy DR. HPV prophylactic vaccines and the potential prevention of noncervical cancers in both men and women. Cancer 2008, 113:3036-3046. 10.1002/cncr.23764, 18980286.
    • (2008) Cancer , vol.113 , pp. 3036-3046
    • Gillison, M.L.1    Chaturvedi, A.K.2    Lowy, D.R.3
  • 8
    • 0033998608 scopus 로고    scopus 로고
    • Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31
    • 10.1128/JVI.74.9.4174-4182.2000, 111932, 10756030
    • Chang YE, Laimins LA. Microarray analysis identifies interferon-inducible genes and Stat-1 as major transcriptional targets of human papillomavirus type 31. J Virol 2000, 74:4174-4182. 10.1128/JVI.74.9.4174-4182.2000, 111932, 10756030.
    • (2000) J Virol , vol.74 , pp. 4174-4182
    • Chang, Y.E.1    Laimins, L.A.2
  • 9
    • 0035047160 scopus 로고    scopus 로고
    • Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes
    • 10.1128/JVI.75.9.4283-4296.2001, 114174, 11287578
    • Nees M, Geoghegan JM, Hyman T, Frank S, Miller L, Woodworth CD. Papillomavirus type 16 oncogenes downregulate expression of interferon-responsive genes and upregulate proliferation-associated and NF-kappaB-responsive genes in cervical keratinocytes. J Virol 2001, 75:4283-4296. 10.1128/JVI.75.9.4283-4296.2001, 114174, 11287578.
    • (2001) J Virol , vol.75 , pp. 4283-4296
    • Nees, M.1    Geoghegan, J.M.2    Hyman, T.3    Frank, S.4    Miller, L.5    Woodworth, C.D.6
  • 10
    • 0033526860 scopus 로고    scopus 로고
    • The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha
    • 10.1006/viro.1999.9771, 10388655
    • Barnard P, McMillan NA. The human papillomavirus E7 oncoprotein abrogates signaling mediated by interferon-alpha. Virology 1999, 259:305-313. 10.1006/viro.1999.9771, 10388655.
    • (1999) Virology , vol.259 , pp. 305-313
    • Barnard, P.1    McMillan, N.A.2
  • 11
    • 0032128003 scopus 로고    scopus 로고
    • Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity
    • 10.1101/gad.12.13.2061, 316980, 9649509
    • Ronco LV, Karpova AY, Vidal M, Howley PM. Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity. Genes Dev 1998, 12:2061-2072. 10.1101/gad.12.13.2061, 316980, 9649509.
    • (1998) Genes Dev , vol.12 , pp. 2061-2072
    • Ronco, L.V.1    Karpova, A.Y.2    Vidal, M.3    Howley, P.M.4
  • 12
    • 64049114881 scopus 로고    scopus 로고
    • Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins
    • 10.1002/rmv.605, 19156753
    • Yugawa T, Kiyono T. Molecular mechanisms of cervical carcinogenesis by high-risk human papillomaviruses: novel functions of E6 and E7 oncoproteins. Rev Med Virol 2009, 19:97-113. 10.1002/rmv.605, 19156753.
    • (2009) Rev Med Virol , vol.19 , pp. 97-113
    • Yugawa, T.1    Kiyono, T.2
  • 13
    • 0032840918 scopus 로고    scopus 로고
    • Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
    • 10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F, 10451482
    • Walboomers JM, Jacobs MV, Manos MM, Bosch FX, Kummer JA, Shah KV, Snijders PJ, Peto J, Meijer CJ, Munoz N. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999, 189:12-19. 10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F, 10451482.
    • (1999) J Pathol , vol.189 , pp. 12-19
    • Walboomers, J.M.1    Jacobs, M.V.2    Manos, M.M.3    Bosch, F.X.4    Kummer, J.A.5    Shah, K.V.6    Snijders, P.J.7    Peto, J.8    Meijer, C.J.9    Munoz, N.10
  • 14
    • 78649381966 scopus 로고    scopus 로고
    • The role of human papillomavirus infection in head and neck cancers
    • Syrjanen S. The role of human papillomavirus infection in head and neck cancers. Ann Oncol 2010, 21(Suppl 7):vii243-vii245.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 7 , pp. 7243-7245
    • Syrjanen, S.1
  • 15
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • 10.1016/S0168-1702(02)00190-9, 12445661
    • Munger K, Howley PM. Human papillomavirus immortalization and transformation functions. Virus Res 2002, 89:213-228. 10.1016/S0168-1702(02)00190-9, 12445661.
    • (2002) Virus Res , vol.89 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 16
    • 0035929353 scopus 로고    scopus 로고
    • Switching and signaling at the telomere
    • 10.1016/S0092-8674(01)00492-5, 11572773
    • Blackburn EH. Switching and signaling at the telomere. Cell 2001, 106:661-673. 10.1016/S0092-8674(01)00492-5, 11572773.
    • (2001) Cell , vol.106 , pp. 661-673
    • Blackburn, E.H.1
  • 18
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • 10.1038/345458a0, 2342578
    • Harley CB, Futcher AB, Greider CW. Telomeres shorten during ageing of human fibroblasts. Nature 1990, 345:458-460. 10.1038/345458a0, 2342578.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 20
    • 0035812845 scopus 로고    scopus 로고
    • The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability
    • 10.1016/S0092-8674(01)00504-9, 11595186
    • Hemann MT, Strong MA, Hao LY, Greider CW. The shortest telomere, not average telomere length, is critical for cell viability and chromosome stability. Cell 2001, 107:67-77. 10.1016/S0092-8674(01)00504-9, 11595186.
    • (2001) Cell , vol.107 , pp. 67-77
    • Hemann, M.T.1    Strong, M.A.2    Hao, L.Y.3    Greider, C.W.4
  • 22
    • 0030008177 scopus 로고    scopus 로고
    • Telomerase activation by the E6 gene product of human papillomavirus type 16
    • 10.1038/380079a0, 8598912
    • Klingelhutz AJ, Foster SA, McDougall JK. Telomerase activation by the E6 gene product of human papillomavirus type 16. Nature 1996, 380:79-82. 10.1038/380079a0, 8598912.
    • (1996) Nature , vol.380 , pp. 79-82
    • Klingelhutz, A.J.1    Foster, S.A.2    McDougall, J.K.3
  • 23
    • 0036143843 scopus 로고    scopus 로고
    • Telomerase in cancer and aging
    • 10.1016/S1040-8428(01)00188-3, 11796230
    • Granger MP, Wright WE, Shay JW. Telomerase in cancer and aging. Crit Rev Oncol Hematol 2002, 41:29-40. 10.1016/S1040-8428(01)00188-3, 11796230.
    • (2002) Crit Rev Oncol Hematol , vol.41 , pp. 29-40
    • Granger, M.P.1    Wright, W.E.2    Shay, J.W.3
  • 25
    • 33748587841 scopus 로고    scopus 로고
    • A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes
    • 10.1016/j.cell.2006.07.031, 16990141
    • Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM, Lim B, Rigoutsos I. A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell 2006, 126:1203-1217. 10.1016/j.cell.2006.07.031, 16990141.
    • (2006) Cell , vol.126 , pp. 1203-1217
    • Miranda, K.C.1    Huynh, T.2    Tay, Y.3    Ang, Y.S.4    Tam, W.L.5    Thomson, A.M.6    Lim, B.7    Rigoutsos, I.8
  • 27
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • 10.1016/j.cell.2004.12.035, 15652477
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005, 120:15-20. 10.1016/j.cell.2004.12.035, 15652477.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 28
    • 0025953696 scopus 로고
    • The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines
    • 10.1073/pnas.88.13.5523, 51909, 1648218
    • Scheffner M, Munger K, Byrne JC, Howley PM. The state of the p53 and retinoblastoma genes in human cervical carcinoma cell lines. Proc Natl Acad Sci U S A 1991, 88:5523-5527. 10.1073/pnas.88.13.5523, 51909, 1648218.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5523-5527
    • Scheffner, M.1    Munger, K.2    Byrne, J.C.3    Howley, P.M.4
  • 29
    • 0025896299 scopus 로고
    • Status of c-myc, p53 and retinoblastoma genes in human papillomavirus positive and negative squamous cell carcinomas of the anus
    • Crook T, Wrede D, Tidy J, Scholefield J, Crawford L, Vousden KH. Status of c-myc, p53 and retinoblastoma genes in human papillomavirus positive and negative squamous cell carcinomas of the anus. Oncogene 1991, 6:1251-1257.
    • (1991) Oncogene , vol.6 , pp. 1251-1257
    • Crook, T.1    Wrede, D.2    Tidy, J.3    Scholefield, J.4    Crawford, L.5    Vousden, K.H.6
  • 30
    • 1642515808 scopus 로고    scopus 로고
    • Human papillomavirus type 16 and TP53 mutation in oral cancer: matched analysis of the IARC multicenter study
    • 10.1158/0008-5472.CAN-03-3284, 14744758
    • Dai M, Clifford GM, le Calvez F, Castellsague X, Snijders PJ, Pawlita M, Herrero R, Hainaut P, Franceschi S. Human papillomavirus type 16 and TP53 mutation in oral cancer: matched analysis of the IARC multicenter study. Cancer Res 2004, 64:468-471. 10.1158/0008-5472.CAN-03-3284, 14744758.
    • (2004) Cancer Res , vol.64 , pp. 468-471
    • Dai, M.1    Clifford, G.M.2    le Calvez, F.3    Castellsague, X.4    Snijders, P.J.5    Pawlita, M.6    Herrero, R.7    Hainaut, P.8    Franceschi, S.9
  • 31
    • 0027358723 scopus 로고
    • The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53
    • 10.1016/0092-8674(93)90384-3, 8221889
    • Scheffner M, Huibregtse JM, Vierstra RD, Howley PM. The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. Cell 1993, 75:495-505. 10.1016/0092-8674(93)90384-3, 8221889.
    • (1993) Cell , vol.75 , pp. 495-505
    • Scheffner, M.1    Huibregtse, J.M.2    Vierstra, R.D.3    Howley, P.M.4
  • 32
    • 36749050812 scopus 로고    scopus 로고
    • Life and death decisions by the E2F transcription factors
    • 10.1016/j.ceb.2007.10.006, 2268988, 18032011
    • Iaquinta PJ, Lees JA. Life and death decisions by the E2F transcription factors. Curr Opin Cell Biol 2007, 19:649-657. 10.1016/j.ceb.2007.10.006, 2268988, 18032011.
    • (2007) Curr Opin Cell Biol , vol.19 , pp. 649-657
    • Iaquinta, P.J.1    Lees, J.A.2
  • 33
    • 0029834371 scopus 로고    scopus 로고
    • E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway
    • Boyer SN, Wazer DE, Band V. E7 protein of human papilloma virus-16 induces degradation of retinoblastoma protein through the ubiquitin-proteasome pathway. Cancer Res 1996, 56:4620-4624.
    • (1996) Cancer Res , vol.56 , pp. 4620-4624
    • Boyer, S.N.1    Wazer, D.E.2    Band, V.3
  • 34
    • 0001510491 scopus 로고    scopus 로고
    • The RB and p53 pathways in cancer
    • 10.1016/S1535-6108(02)00102-2, 12204530
    • Sherr CJ, McCormick F. The RB and p53 pathways in cancer. Cancer Cell 2002, 2:103-112. 10.1016/S1535-6108(02)00102-2, 12204530.
    • (2002) Cancer Cell , vol.2 , pp. 103-112
    • Sherr, C.J.1    McCormick, F.2
  • 35
    • 70249090057 scopus 로고    scopus 로고
    • The rb pathway and cancer therapeutics
    • 10.2174/138945009788680392, 3151466, 19601762
    • Du W, Searle JS. The rb pathway and cancer therapeutics. Curr Drug Targets 2009, 10:581-589. 10.2174/138945009788680392, 3151466, 19601762.
    • (2009) Curr Drug Targets , vol.10 , pp. 581-589
    • Du, W.1    Searle, J.S.2
  • 36
    • 0031961995 scopus 로고    scopus 로고
    • Effects of p21 (Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication
    • 121530, 9418909
    • Niculescu AB, Chen X, Smeets M, Hengst L, Prives C, Reed SI. Effects of p21 (Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol 1998, 18:629-643. 121530, 9418909.
    • (1998) Mol Cell Biol , vol.18 , pp. 629-643
    • Niculescu, A.B.1    Chen, X.2    Smeets, M.3    Hengst, L.4    Prives, C.5    Reed, S.I.6
  • 38
    • 0035836706 scopus 로고    scopus 로고
    • Myc represses the p21 (WAF1/CIP1) promoter and interacts with Sp1/Sp3
    • 10.1073/pnas.081074898, 31865, 11274368
    • Gartel AL, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F, Tyner AL. Myc represses the p21 (WAF1/CIP1) promoter and interacts with Sp1/Sp3. Proc Natl Acad Sci U S A 2001, 98:4510-4515. 10.1073/pnas.081074898, 31865, 11274368.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4510-4515
    • Gartel, A.L.1    Ye, X.2    Goufman, E.3    Shianov, P.4    Hay, N.5    Najmabadi, F.6    Tyner, A.L.7
  • 39
    • 22744450481 scopus 로고    scopus 로고
    • Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes
    • 10.1038/sj.onc.1208652, 15856024
    • Ceballos E, Munoz-Alonso MJ, Berwanger B, Acosta JC, Hernandez R, Krause M, Hartmann O, Eilers M, Leon J. Inhibitory effect of c-Myc on p53-induced apoptosis in leukemia cells. Microarray analysis reveals defective induction of p53 target genes and upregulation of chaperone genes. Oncogene 2005, 24:4559-4571. 10.1038/sj.onc.1208652, 15856024.
    • (2005) Oncogene , vol.24 , pp. 4559-4571
    • Ceballos, E.1    Munoz-Alonso, M.J.2    Berwanger, B.3    Acosta, J.C.4    Hernandez, R.5    Krause, M.6    Hartmann, O.7    Eilers, M.8    Leon, J.9
  • 40
    • 0033569422 scopus 로고    scopus 로고
    • Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
    • 10.1101/gad.13.20.2658, 317106, 10541552
    • Eischen CM, Weber JD, Roussel MF, Sherr CJ, Cleveland JL. Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis. Genes Dev 1999, 13:2658-2669. 10.1101/gad.13.20.2658, 317106, 10541552.
    • (1999) Genes Dev , vol.13 , pp. 2658-2669
    • Eischen, C.M.1    Weber, J.D.2    Roussel, M.F.3    Sherr, C.J.4    Cleveland, J.L.5
  • 41
    • 0000418970 scopus 로고    scopus 로고
    • C-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells
    • 10.1038/sj.onc.1203541, 10822369
    • Ceballos E, Delgado MD, Gutierrez P, Richard C, Muller D, Eilers M, Ehinger M, Gullberg U, Leon J. c-Myc antagonizes the effect of p53 on apoptosis and p21WAF1 transactivation in K562 leukemia cells. Oncogene 2000, 19:2194-2204. 10.1038/sj.onc.1203541, 10822369.
    • (2000) Oncogene , vol.19 , pp. 2194-2204
    • Ceballos, E.1    Delgado, M.D.2    Gutierrez, P.3    Richard, C.4    Muller, D.5    Eilers, M.6    Ehinger, M.7    Gullberg, U.8    Leon, J.9
  • 42
    • 0024281617 scopus 로고
    • Inactivation of the retinoblastoma susceptibility gene in human breast cancers
    • 10.1126/science.3388033, 3388033
    • Lee EY, To H, Shew JY, Bookstein R, Scully P, Lee WH. Inactivation of the retinoblastoma susceptibility gene in human breast cancers. Science 1988, 241:218-221. 10.1126/science.3388033, 3388033.
    • (1988) Science , vol.241 , pp. 218-221
    • Lee, E.Y.1    To, H.2    Shew, J.Y.3    Bookstein, R.4    Scully, P.5    Lee, W.H.6
  • 44
    • 80455143338 scopus 로고    scopus 로고
    • Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation
    • 10.1016/j.bpj.2011.09.052, 3207173, 22067145
    • Aguda BD, Kim Y, Kim HS, Friedman A, Fine HA. Qualitative network modeling of the Myc-p53 control system of cell proliferation and differentiation. Biophys J 2011, 101:2082-2091. 10.1016/j.bpj.2011.09.052, 3207173, 22067145.
    • (2011) Biophys J , vol.101 , pp. 2082-2091
    • Aguda, B.D.1    Kim, Y.2    Kim, H.S.3    Friedman, A.4    Fine, H.A.5
  • 46
    • 0032792828 scopus 로고    scopus 로고
    • Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells
    • Kusumoto M, Ogawa T, Mizumoto K, Ueno H, Niiyama H, Sato N, Nakamura M, Tanaka M. Adenovirus-mediated p53 gene transduction inhibits telomerase activity independent of its effects on cell cycle arrest and apoptosis in human pancreatic cancer cells. Clin Cancer Res 1999, 5:2140-2147.
    • (1999) Clin Cancer Res , vol.5 , pp. 2140-2147
    • Kusumoto, M.1    Ogawa, T.2    Mizumoto, K.3    Ueno, H.4    Niiyama, H.5    Sato, N.6    Nakamura, M.7    Tanaka, M.8
  • 47
    • 0034048726 scopus 로고    scopus 로고
    • Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription
    • Kanaya T, Kyo S, Hamada K, Takakura M, Kitagawa Y, Harada H, Inoue M. Adenoviral expression of p53 represses telomerase activity through down-regulation of human telomerase reverse transcriptase transcription. Clin Cancer Res 2000, 6:1239-1247.
    • (2000) Clin Cancer Res , vol.6 , pp. 1239-1247
    • Kanaya, T.1    Kyo, S.2    Hamada, K.3    Takakura, M.4    Kitagawa, Y.5    Harada, H.6    Inoue, M.7
  • 49
    • 0035911690 scopus 로고    scopus 로고
    • Rb and E2F-1 regulate telomerase activity in human cancer cells
    • 10.1016/S0167-4781(00)00296-7, 11267653
    • Crowe DL, Nguyen DC. Rb and E2F-1 regulate telomerase activity in human cancer cells. Biochim Biophys Acta 2001, 1518:1-6. 10.1016/S0167-4781(00)00296-7, 11267653.
    • (2001) Biochim Biophys Acta , vol.1518 , pp. 1-6
    • Crowe, D.L.1    Nguyen, D.C.2
  • 50
    • 33646898172 scopus 로고    scopus 로고
    • Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms
    • 10.1016/j.semcancer.2006.03.007, 16678437
    • Gardino AK, Smerdon SJ, Yaffe MB. Structural determinants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms. Semin Cancer Biol 2006, 16:173-182. 10.1016/j.semcancer.2006.03.007, 16678437.
    • (2006) Semin Cancer Biol , vol.16 , pp. 173-182
    • Gardino, A.K.1    Smerdon, S.J.2    Yaffe, M.B.3
  • 51
    • 0034212582 scopus 로고    scopus 로고
    • Involvement of 14-3-3 proteins in nuclear localization of telomerase
    • 10.1093/emboj/19.11.2652, 212742, 10835362
    • Seimiya H, Sawada H, Muramatsu Y, Shimizu M, Ohko K, Yamane K, Tsuruo T. Involvement of 14-3-3 proteins in nuclear localization of telomerase. EMBO J 2000, 19:2652-2661. 10.1093/emboj/19.11.2652, 212742, 10835362.
    • (2000) EMBO J , vol.19 , pp. 2652-2661
    • Seimiya, H.1    Sawada, H.2    Muramatsu, Y.3    Shimizu, M.4    Ohko, K.5    Yamane, K.6    Tsuruo, T.7
  • 52
    • 78751660177 scopus 로고    scopus 로고
    • Pervasive roles of microRNAs in cardiovascular biology
    • 10.1038/nature09783, 3073349, 21248840
    • Small EM, Olson EN. Pervasive roles of microRNAs in cardiovascular biology. Nature 2011, 469:336-342. 10.1038/nature09783, 3073349, 21248840.
    • (2011) Nature , vol.469 , pp. 336-342
    • Small, E.M.1    Olson, E.N.2
  • 53
    • 49949117302 scopus 로고    scopus 로고
    • Widespread changes in protein synthesis induced by microRNAs
    • 10.1038/nature07228, 18668040
    • Selbach M, Schwanhausser B, Thierfelder N, Fang Z, Khanin R, Rajewsky N. Widespread changes in protein synthesis induced by microRNAs. Nature 2008, 455:58-63. 10.1038/nature07228, 18668040.
    • (2008) Nature , vol.455 , pp. 58-63
    • Selbach, M.1    Schwanhausser, B.2    Thierfelder, N.3    Fang, Z.4    Khanin, R.5    Rajewsky, N.6
  • 56
    • 65249186738 scopus 로고    scopus 로고
    • MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma
    • 10.1158/1078-0432.CCR-08-3131, 2669849, 19351747
    • Avissar M, Christensen BC, Kelsey KT, Marsit CJ. MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin Cancer Res 2009, 15:2850-2855. 10.1158/1078-0432.CCR-08-3131, 2669849, 19351747.
    • (2009) Clin Cancer Res , vol.15 , pp. 2850-2855
    • Avissar, M.1    Christensen, B.C.2    Kelsey, K.T.3    Marsit, C.J.4
  • 59
    • 80054991467 scopus 로고    scopus 로고
    • MiR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1
    • 10.1016/j.ajpath.2011.07.037, 3204087, 21945323
    • Wang F, Li Y, Zhou J, Xu J, Peng C, Ye F, Shen Y, Lu W, Wan X, Xie X. miR-375 is down-regulated in squamous cervical cancer and inhibits cell migration and invasion via targeting transcription factor SP1. Am J Pathol 2011, 179:2580-2588. 10.1016/j.ajpath.2011.07.037, 3204087, 21945323.
    • (2011) Am J Pathol , vol.179 , pp. 2580-2588
    • Wang, F.1    Li, Y.2    Zhou, J.3    Xu, J.4    Peng, C.5    Ye, F.6    Shen, Y.7    Lu, W.8    Wan, X.9    Xie, X.10
  • 60
    • 46249083024 scopus 로고    scopus 로고
    • MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations
    • 10.1002/hep.22256, 18433021
    • Ladeiro Y, Couchy G, Balabaud C, Bioulac-Sage P, Pelletier L, Rebouissou S, Zucman-Rossi J. MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology 2008, 47:1955-1963. 10.1002/hep.22256, 18433021.
    • (2008) Hepatology , vol.47 , pp. 1955-1963
    • Ladeiro, Y.1    Couchy, G.2    Balabaud, C.3    Bioulac-Sage, P.4    Pelletier, L.5    Rebouissou, S.6    Zucman-Rossi, J.7
  • 61
    • 83555177355 scopus 로고    scopus 로고
    • MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor
    • 10.1136/gutjnl-2011-300178, 21813472
    • Kong KL, Kwong DL, Chan TH, Law SY, Chen L, Li Y, Qin YR, Guan XY. MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor. Gut 2012, 61:33-42. 10.1136/gutjnl-2011-300178, 21813472.
    • (2012) Gut , vol.61 , pp. 33-42
    • Kong, K.L.1    Kwong, D.L.2    Chan, T.H.3    Law, S.Y.4    Chen, L.5    Li, Y.6    Qin, Y.R.7    Guan, X.Y.8
  • 62
    • 77955708471 scopus 로고    scopus 로고
    • MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2
    • 10.1038/cr.2010.79, 20548334
    • Ding L, Xu Y, Zhang W, Deng Y, Si M, Du Y, Yao H, Liu X, Ke Y, Si J, Zhou T. MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res 2010, 20:784-793. 10.1038/cr.2010.79, 20548334.
    • (2010) Cell Res , vol.20 , pp. 784-793
    • Ding, L.1    Xu, Y.2    Zhang, W.3    Deng, Y.4    Si, M.5    Du, Y.6    Yao, H.7    Liu, X.8    Ke, Y.9    Si, J.10    Zhou, T.11
  • 63
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • 10.1016/0092-8674(90)90409-8, 2175676
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1990, 63:1129-1136. 10.1016/0092-8674(90)90409-8, 2175676.
    • (1990) Cell , vol.63 , pp. 1129-1136
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 66
    • 0028331229 scopus 로고
    • Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins
    • 10.1101/gad.8.6.666, 7926757
    • White AE, Livanos EM, Tlsty TD. Differential disruption of genomic integrity and cell cycle regulation in normal human fibroblasts by the HPV oncoproteins. Genes Dev 1994, 8:666-677. 10.1101/gad.8.6.666, 7926757.
    • (1994) Genes Dev , vol.8 , pp. 666-677
    • White, A.E.1    Livanos, E.M.2    Tlsty, T.D.3
  • 67
    • 0036784599 scopus 로고    scopus 로고
    • Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells
    • 10.1128/JVI.76.20.10559-10568.2002, 136576, 12239337
    • Helt AM, Funk JO, Galloway DA. Inactivation of both the retinoblastoma tumor suppressor and p21 by the human papillomavirus type 16 E7 oncoprotein is necessary to inhibit cell cycle arrest in human epithelial cells. J Virol 2002, 76:10559-10568. 10.1128/JVI.76.20.10559-10568.2002, 136576, 12239337.
    • (2002) J Virol , vol.76 , pp. 10559-10568
    • Helt, A.M.1    Funk, J.O.2    Galloway, D.A.3
  • 68
    • 1842575867 scopus 로고    scopus 로고
    • Splicing of a cap-proximal human Papillomavirus 16 E6E7 intron promotes E7 expression, but can be restrained by distance of the intron from its RNA 5' cap
    • 10.1016/j.jmb.2004.02.023, 15046980
    • Zheng ZM, Tao M, Yamanegi K, Bodaghi S, Xiao W. Splicing of a cap-proximal human Papillomavirus 16 E6E7 intron promotes E7 expression, but can be restrained by distance of the intron from its RNA 5' cap. J Mol Biol 2004, 337:1091-1108. 10.1016/j.jmb.2004.02.023, 15046980.
    • (2004) J Mol Biol , vol.337 , pp. 1091-1108
    • Zheng, Z.M.1    Tao, M.2    Yamanegi, K.3    Bodaghi, S.4    Xiao, W.5
  • 69
    • 33646167060 scopus 로고    scopus 로고
    • The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiation
    • 10.1128/JVI.80.9.4249-4263.2006, 1472016, 16611884
    • Tang S, Tao M, McCoy JP, Zheng ZM. The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiation. J Virol 2006, 80:4249-4263. 10.1128/JVI.80.9.4249-4263.2006, 1472016, 16611884.
    • (2006) J Virol , vol.80 , pp. 4249-4263
    • Tang, S.1    Tao, M.2    McCoy, J.P.3    Zheng, Z.M.4
  • 70
    • 77951044009 scopus 로고    scopus 로고
    • Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation
    • 10.1073/pnas.1002620107, 2872467, 20351270
    • Rosenberger S, De-Castro Arce J, Langbein L, Steenbergen RD, Rosl F. Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation. Proc Natl Acad Sci U S A 2010, 107:7006-7011. 10.1073/pnas.1002620107, 2872467, 20351270.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7006-7011
    • Rosenberger, S.1    De-Castro Arce, J.2    Langbein, L.3    Steenbergen, R.D.4    Rosl, F.5
  • 71
    • 42249105032 scopus 로고    scopus 로고
    • Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells
    • 10.1038/sj.onc.1210919, 2447163, 17998940
    • Martinez I, Gardiner AS, Board KF, Monzon FA, Edwards RP, Khan SA. Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells. Oncogene 2008, 27:2575-2582. 10.1038/sj.onc.1210919, 2447163, 17998940.
    • (2008) Oncogene , vol.27 , pp. 2575-2582
    • Martinez, I.1    Gardiner, A.S.2    Board, K.F.3    Monzon, F.A.4    Edwards, R.P.5    Khan, S.A.6
  • 72
    • 62549156668 scopus 로고    scopus 로고
    • Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6
    • 10.1261/rna.1442309, 2661824, 19258450
    • Wang X, Wang HK, McCoy JP, Banerjee NS, Rader JS, Broker TR, Meyers C, Chow LT, Zheng ZM. Oncogenic HPV infection interrupts the expression of tumor-suppressive miR-34a through viral oncoprotein E6. RNA 2009, 15:637-647. 10.1261/rna.1442309, 2661824, 19258450.
    • (2009) RNA , vol.15 , pp. 637-647
    • Wang, X.1    Wang, H.K.2    McCoy, J.P.3    Banerjee, N.S.4    Rader, J.S.5    Broker, T.R.6    Meyers, C.7    Chow, L.T.8    Zheng, Z.M.9
  • 73
    • 79957611432 scopus 로고    scopus 로고
    • Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway
    • 10.1038/onc.2010.613, 21242962
    • Au Yeung CL, Tsang TY, Yau PL, Kwok TT. Human papillomavirus type 16 E6 induces cervical cancer cell migration through the p53/microRNA-23b/urokinase-type plasminogen activator pathway. Oncogene 2011, 30:2401-2410. 10.1038/onc.2010.613, 21242962.
    • (2011) Oncogene , vol.30 , pp. 2401-2410
    • Au Yeung, C.L.1    Tsang, T.Y.2    Yau, P.L.3    Kwok, T.T.4
  • 74
    • 84866248074 scopus 로고    scopus 로고
    • Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells
    • 10.1002/path.3997, 22287315
    • Shi M, Du L, Liu D, Qian L, Hu M, Yu M, Yang Z, Zhao M, Chen C, Guo L, Wang L, Song L, Ma Y, Guo N. Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells. J Pathol 2012, 228:148-157. 10.1002/path.3997, 22287315.
    • (2012) J Pathol , vol.228 , pp. 148-157
    • Shi, M.1    Du, L.2    Liu, D.3    Qian, L.4    Hu, M.5    Yu, M.6    Yang, Z.7    Zhao, M.8    Chen, C.9    Guo, L.10    Wang, L.11    Song, L.12    Ma, Y.13    Guo, N.14
  • 75
    • 77951454817 scopus 로고    scopus 로고
    • Human papillomaviruses modulate expression of microRNA 203 upon epithelial differentiation to control levels of p63 proteins
    • 10.1128/JVI.00078-10, 2863797, 20219920
    • Melar-New M, Laimins LA. Human papillomaviruses modulate expression of microRNA 203 upon epithelial differentiation to control levels of p63 proteins. J Virol 2010, 84:5212-5221. 10.1128/JVI.00078-10, 2863797, 20219920.
    • (2010) J Virol , vol.84 , pp. 5212-5221
    • Melar-New, M.1    Laimins, L.A.2
  • 81
    • 80655127810 scopus 로고
    • Regulation of cellular miRNA expression by human papillomaviruses
    • Zheng ZM, Wang X. Regulation of cellular miRNA expression by human papillomaviruses. Biochim Biophys Acta 1809, 2011:668-677.
    • (1809) Biochim Biophys Acta , vol.2011 , pp. 668-677
    • Zheng, Z.M.1    Wang, X.2
  • 82
    • 0026671476 scopus 로고
    • Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation
    • 10.1126/science.1323879, 1323879
    • Meyers C, Frattini MG, Hudson JB, Laimins LA. Biosynthesis of human papillomavirus from a continuous cell line upon epithelial differentiation. Science 1992, 257:971-973. 10.1126/science.1323879, 1323879.
    • (1992) Science , vol.257 , pp. 971-973
    • Meyers, C.1    Frattini, M.G.2    Hudson, J.B.3    Laimins, L.A.4
  • 83
    • 1842343575 scopus 로고
    • Human papillomavirus type 16 alters human epithelial cell differentiation in vitro
    • 10.1073/pnas.85.19.7169, 282145, 2459699
    • McCance DJ, Kopan R, Fuchs E, Laimins LA. Human papillomavirus type 16 alters human epithelial cell differentiation in vitro. Proc Natl Acad Sci U S A 1988, 85:7169-7173. 10.1073/pnas.85.19.7169, 282145, 2459699.
    • (1988) Proc Natl Acad Sci U S A , vol.85 , pp. 7169-7173
    • McCance, D.J.1    Kopan, R.2    Fuchs, E.3    Laimins, L.A.4
  • 84
    • 84865475867 scopus 로고    scopus 로고
    • Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer
    • 10.1074/jbc.M112.366518, 3436145, 22761427
    • Jung HM, Phillips BL, Patel RS, Cohen DM, Jakymiw A, Kong WW, Cheng JQ, Chan EK. Keratinization-associated miR-7 and miR-21 Regulate Tumor Suppressor Reversion-inducing Cysteine-rich Protein with Kazal Motifs (RECK) in Oral Cancer. J Biol Chem 2012, 287:29261-29272. 10.1074/jbc.M112.366518, 3436145, 22761427.
    • (2012) J Biol Chem , vol.287 , pp. 29261-29272
    • Jung, H.M.1    Phillips, B.L.2    Patel, R.S.3    Cohen, D.M.4    Jakymiw, A.5    Kong, W.W.6    Cheng, J.Q.7    Chan, E.K.8
  • 85
    • 2942579108 scopus 로고    scopus 로고
    • Mapping and analysis of HPV16 integration sites in a head and neck cancer cell line
    • 10.1002/ijc.20193, 15146560
    • Ragin CC, Reshmi SC, Gollin SM. Mapping and analysis of HPV16 integration sites in a head and neck cancer cell line. Int J Cancer 2004, 110:701-709. 10.1002/ijc.20193, 15146560.
    • (2004) Int J Cancer , vol.110 , pp. 701-709
    • Ragin, C.C.1    Reshmi, S.C.2    Gollin, S.M.3
  • 86
    • 14744275857 scopus 로고    scopus 로고
    • The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase
    • 10.1128/JVI.79.6.3737-3747.2005, 1075713, 15731267
    • Kelley ML, Keiger KE, Lee CJ, Huibregtse JM. The global transcriptional effects of the human papillomavirus E6 protein in cervical carcinoma cell lines are mediated by the E6AP ubiquitin ligase. J Virol 2005, 79:3737-3747. 10.1128/JVI.79.6.3737-3747.2005, 1075713, 15731267.
    • (2005) J Virol , vol.79 , pp. 3737-3747
    • Kelley, M.L.1    Keiger, K.E.2    Lee, C.J.3    Huibregtse, J.M.4
  • 87
    • 77952019174 scopus 로고    scopus 로고
    • Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells
    • 10.1002/gcc.20765, 2859695, 20232482
    • Jakymiw A, Patel RS, Deming N, Bhattacharyya I, Shah P, Lamont RJ, Stewart CM, Cohen DM, Chan EK. Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosomes Cancer 2010, 49:549-559. 10.1002/gcc.20765, 2859695, 20232482.
    • (2010) Genes Chromosomes Cancer , vol.49 , pp. 549-559
    • Jakymiw, A.1    Patel, R.S.2    Deming, N.3    Bhattacharyya, I.4    Shah, P.5    Lamont, R.J.6    Stewart, C.M.7    Cohen, D.M.8    Chan, E.K.9
  • 88
    • 67650066325 scopus 로고    scopus 로고
    • RNA (E6 and E7) assays versus DNA (E6 and E7) assays for risk evaluation for women infected with human papillomavirus
    • 10.1128/JCM.01733-08, 2708475, 19403762
    • Cattani P, Siddu A, D'Onghia S, Marchetti S, Santangelo R, Vellone VG, Zannoni GF, Fadda G. RNA (E6 and E7) assays versus DNA (E6 and E7) assays for risk evaluation for women infected with human papillomavirus. J Clin Microbiol 2009, 47:2136-2141. 10.1128/JCM.01733-08, 2708475, 19403762.
    • (2009) J Clin Microbiol , vol.47 , pp. 2136-2141
    • Cattani, P.1    Siddu, A.2    D'Onghia, S.3    Marchetti, S.4    Santangelo, R.5    Vellone, V.G.6    Zannoni, G.F.7    Fadda, G.8
  • 89
    • 0037440078 scopus 로고    scopus 로고
    • SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity
    • 140528, 12527792
    • Wege H, Chui MS, Le HT, Tran JM, Zern MA. SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity. Nucleic Acids Res 2003, 31:E3-E13. 140528, 12527792.
    • (2003) Nucleic Acids Res , vol.31
    • Wege, H.1    Chui, M.S.2    Le, H.T.3    Tran, J.M.4    Zern, M.A.5
  • 90
    • 0037173724 scopus 로고    scopus 로고
    • Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer
    • 10.1038/sj.onc.1205625, 12118381
    • Soo Hoo L, Zhang JY, Chan EKL. Cloning and characterization of a novel 90 kDa 'companion' auto-antigen of p62 overexpressed in cancer. Oncogene 2002, 21:5006-5015. 10.1038/sj.onc.1205625, 12118381.
    • (2002) Oncogene , vol.21 , pp. 5006-5015
    • Soo Hoo, L.1    Zhang, J.Y.2    Chan, E.K.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.