Evidences of +896 A/G TLR4 polymorphism as an indicative of prevalence of complications in T2DM patients

Mediators of Inflammation

Volumn 2014, Issue , 2014, Pages

  Balistreri, Carmela Rita ^a   Bonfigli, Anna Rita ^b   Boemi, Massimo ^b   Olivieri, Fabiola ^b,c   Ceriello, Antonio ^d,e   Genovese, Stefano ^f   Franceschi, Claudio ^g   Spazzafumo, Liana ^b   Fabietti, Paolo ^b   Candore, Giuseppina ^a   Caruso, Calogero ^a   Lio, Domenico ^a   Testa, Roberto ^b  

^a UNIVERSITY OF PALERMO   (Italy)

^b INRCA   (Italy)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^d INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f IRCCS MULTIMEDICA   (Italy)

^g UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN A1; C REACTIVE PROTEIN; CHOLESTEROL; CREATININE; FIBRINOGEN; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HIGH SENSITIVITY C REACTIVE PROTEIN; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG; UREA; TLR4 PROTEIN, HUMAN;

ADULT; AGED; ARTERY DISEASE; ARTICLE; CAUCASIAN; CHRONIC KIDNEY FAILURE; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC PATIENT; DIABETIC RETINOPATHY; DISEASE ASSOCIATION; FEMALE; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENOTYPE; HEREDITY; HETEROZYGOTE; HUMAN; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; KIDNEY FAILURE; MAJOR CLINICAL STUDY; MALE; NEUROPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; SINGLE NUCLEOTIDE POLYMORPHISM; COMPLICATION; GENE FREQUENCY; GENETICS; MIDDLE AGED; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; DIABETES MELLITUS, TYPE 2; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TOLL-LIKE RECEPTOR 4;

EID: 84899479667     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/973139     Document Type: Article

References (48)

1. Unwin N., Whiting D., Guariguata L., Ghyoot G., Gan D., International diabetes federation. Updated Diabetes Atlas 2011 5th Brussels, Belgium
2. Balistreri C. R., Caruso C., Candore G., The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediators of Inflammation 2010 2010 19 2-s2.0-77955404414 10.1155/2010/802078 802078
3. Hotamisligil G. S., Inflammation and metabolic disorders. Nature 2006 444 7121 860 867 2-s2.0-33845866857 10.1038/nature05485 (Pubitemid 46024993)
4. Lontchi-Yimagou E., Sobngwi E., Matsha T. E., Kengne A. P., Diabetes mellitus and inflammation. Current Diabetes Report 2013 13 435 444
5. Kolb H., Mandrup-Poulsen T., An immune origin of type 2 diabetes? Diabetologia 2005 48 6 1038 1050 2-s2.0-21344460247 10.1007/s00125-005-1764-9 (Pubitemid 40909636)
6. Shoelson S. E., Lee J., Goldfine A. B., Inflammation and insulin resistance. Journal of Clinical Investigation 2006 116 7 1793 1801 2-s2.0-33745861300 10.1172/JCI29069
7. Okada T., Chong W. L., Hu J., Hinault C., Michael M. D., Krützfeldt J., Yin C., Holzenberger M., Stoffel M., Kulkarni R. N., Insulin receptors in β -cells are critical for islet compensatory growth response to insulin resistance. Proceedings of the National Academy of Sciences of the United States of America 2007 104 21 8977 8982 2-s2.0-34547482573 10.1073/pnas.0608703104 (Pubitemid 47175422)
8. Wang Q., Jin T., The role of insulin signaling in the development of β -cell dysfunction and diabetes. Islets 2009 1 2 95 101 2-s2.0-79953242703
9. Balistreri C. R., Colonna-Romano G., Lio D., Candore G., Caruso C., TLR4 polymorphisms and ageing: implications for the pathophysiology of age-related diseases. Journal of Clinical Immunology 2009 29 4 406 415 2-s2.0-67651213832 10.1007/s10875-009-9297-5
10. Sirisinha S., Insight into the mechanisms regulating immunehomeostasis in health and disease. Asian Pacific Journal of Allergy and Immunology 2011 29 1 1 14 2-s2.0-79958276436
11. Newton K., Dixit V. M., Signaling in innate immunity and inflammation. Cold Spring Harbor Perspectives in Biology 2012 4 3 006049 10.1101/cshperspect. a006049
12. Hutton M. J., Soukhatcheva G., Johnson J. D., Verchere C. B., Role of the TLR signalling molecule TRIF in beta-cell function and glucose homeostasis. Islets 2010 2 2 104 111 10.4161/isl.2.2.11209 2-s2.0-77953402405
13. Garay-Malpartida H. M., Mourão R. F., Mantovani M., Santos I. A., Sogayar M. C., Goldberg A. C., Toll-like receptor 4 (TLR4) expression in human and murine pancreatic beta-cells affects cell viability and insulin homeostasis. BMC Immunology 2011 12, article 18 2-s2.0-79952044141 10.1186/1471-2172-12-18
14. Ellingsgaard H., Hauselmann I., Schuler B., Habib A. M., Baggio L. L., Meier D. T., Eppler E., Bouzakri K., Wueest S., Muller Y. D., Hansen A. M. K., Reinecke M., Konrad D., Gassmann M., Reimann F., Halban P. A., Gromada J., Drucker D. J., Gribble F. M., Ehses J. A., Donath M. Y., Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nature Medicine 2011 17 11 1481 1489 2-s2.0-81255157471 10.1038/nm.2513
15. Amyot J., Semache M., Ferdaoussi M., Fontés G., Poitout V., Lipopolysaccharides impair insulin gene expression in isolated islets of langerhans via toll-like receptor-4 and nf- b signalling. PLoS ONE 2012 7 4 2-s2.0-84860485809 10.1371/journal.pone.0036200 e36200
16. Shi H., Kokoeva M. V., Inouye K., Tzameli I., Yin H., Flier J. S., TLR4 links innate immunity and fatty acid-induced insulin resistance. Journal of Clinical Investigation 2006 116 11 3015 3025 2-s2.0-33750584214 10.1172/JCI28898 (Pubitemid 44684486)
17. Tsukumo D. M. L., Carvalho-Filho M. A., Carvalheira J. B. C., Prada P. O., Hirabara S. M., Schenka A. A., Araújo E. P., Vassallo J., Curi R., Velloso L. A., Saad M. J. A., Loss-of-function mutation in toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 2007 56 8 1986 1998 2-s2.0-34547602916 10.2337/db06-1595 (Pubitemid 47195825)
18. Suganami T., Mieda T., Itoh M., Shimoda Y., Kamei Y., Ogawa Y., Attenuation of obesity-induced adipose tissue inflammation in C3H/HeJ mice carrying a Toll-like receptor 4 mutation. Biochemical and Biophysical Research Communications 2007 354 1 45 49 2-s2.0-33846302361 10.1016/j.bbrc.2006.12.190 (Pubitemid 46123196)
19. Balistreri C. R., Caruso C., Listì F., Colonna-Romano G., Lio D., Candore G., LPS-mediated production of pro/anti-inflammatory cytokines and eicosanoids in whole blood samples: biological effects of +896A/G TLR4 polymorphism in a Sicilian population of healthy subjects. Mechanisms of Ageing and Development 2011 132 3 86 92 2-s2.0-79952758944 10.1016/j.mad.2010.12.005
20. Belforte F. S., Coluccio Leskow F., Poskus E., Penas Steinhardt A., Toll-like receptor 4 D299G polymorphism in metabolic disorders: a meta-analysis. Molecular Biology Reports 2013 40 3015 3020
21. Buraczynska M., Baranowicz-Gaszczyk I., Tarach J., Ksiazek A., Toll-like receptor 4 gene polymorphism and early onset of diabetic retinopathy in patients with type 2 diabetes. Human Immunology 2009 70 2 121 124 2-s2.0-59649101088 10.1016/j.humimm.2008.12.003
22. Lirussi F., The global challenge of type 2 diabetes and the strategies for response in ethnic minority groups. Diabetes/Metabolism Research and Reviews 2010 26 6 421 432 2-s2.0-77956623135 10.1002/dmrr.1105
23. Wilson P. W. F., Meigs J. B., Sullivan L., Fox C. S., Nathan D. M., D'Agostino R. B. Sr., Prediction of incident diabetes mellitus in middle-aged adults: the framingham offspring study. Archives of Internal Medicine 2007 167 10 1068 1074 2-s2.0-34249654186 10.1001/archinte.167.10.1068 (Pubitemid 46835795)
24. Talmud P. J., Hingorani A. D., Cooper J. A., Marmot M. G., Brunner E. J., Kumari M., Kivimäki M., Humphries S. E., Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: whitehall II prospective cohort study. British Medical Journal 2010 340 b4838 2-s2.0-75649134649 10.1136/bmj.b4838
25. Kolek M. J., Carlquist J. F., Muhlestein J. B., Whiting B. M., Horne B. D., Bair T. L., Anderson J. L., Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. American Heart Journal 2004 148 6 1034 1040 2-s2.0-10644236977 10.1016/j.ahj.2004.05.049 (Pubitemid 39646980)
26. Rudofsky G. Jr., Reismann P., Witte S., Humpert P. M., Isermann B., Chavakis T., Tafel J., Nosikov V. V., Hamann A., Nawroth P., Bierhaus A., Asp299Gly and Thr399Ile genotypes of the TLR4 Gene are associated with a reduced prevalence of diabetic neuropathy in patients with Type 2 diabetes. Diabetes Care 2004 27 1 179 183 2-s2.0-10744224562 10.2337/diacare.27.1.179 (Pubitemid 38196729)
27. Liu F., Lu W., Qian Q., Qi W., Hu J., Feng B., Frequency of TLR 2, 4, and 9 gene polymorphisms in Chinese population and their susceptibility to type 2 diabetes and coronary artery disease. Journal of Biomedice and Biotechnology 2012 2012 7 10.1155/2012/373945 373945
28. American Diabetes Association, Diagnosis and classification of diabetes mellitus. Diabetes Care 2007 30 S42 S47
29. Cockcroft D. W., Gault M. H., Prediction of creatinine clearance from serum creatinine. Nephron 1976 16 1 31 41 2-s2.0-0016916438
30. Matthews D. R., Hosker J. P., Rudenski A. S., Homeostasis model assessment: insulin resistance and β -cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 7 412 419 2-s2.0-0021813187 (Pubitemid 15018832)
31. Balistreri C. R., Grimaldi M. P., Chiappelli M., Licastro F., Castiglia L., Listi F., Vasto S., Lio D., Caruso C., Candore G., Association between the polymorphisms of TLR4 and CD14 genes and Alzheimer's disease. Current Pharmaceutical Design 2008 14 26 2672 2677 2-s2.0-57349160857 10.2174/138161208786264089
32. Dasu M. R., Devaraj S., Zhao L., Hwang D. H., Jialal I., High glucose induces toll-like receptor expression in human monocytes Mechanism of activation. Diabetes 2008 57 11 3090 3098 2-s2.0-58149333718 10.2337/db08-0564
33. Dasu M. R., Jialal I., Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. American Journal of Physiology-Endocrinology and Metabolism 2011 300 1 E145 E154 2-s2.0-78650773537 10.1152/ajpendo.00490.2010
34. Dasu M. R., Ramirez S., Isseroff R. R., Toll-like receptors and diabetes: a therapeutic perspective. Clinical Science 2012 122 5 203 214 2-s2.0-84855481978 10.1042/CS20110357
35. Kim J. J., Sears D. D., TLR4 and insulin resistance. Gastroenterology Research and Practice 2010 2010 11 2-s2.0-77956790572 10.1155/2010/212563 212563
36. Ladefoged M., Buschard K., Hansen A. M., Increased expression of toll-like receptor 4 and inflammatory cytokines, interleukin-6 in particular, in islets from a mouse model of obesity and type 2 diabetes. Acta Pathologica, Microbiologica, et Immunologica Scandinavica 2013 121 531 538
37. Stegenga M. E., van der Crabben S. N., Blümer R. M. E., Levi M., Meijers J. C. M., Serlie M. J., Tanck M. W. T., Sauerwein H. P., Van Der Poll T., Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia. Blood 2008 112 1 82 89 2-s2.0-47249138753 10.1182/blood-2007-11-121723
38. Peraldi M.-N., Berrou J., Dulphy N., Seidowsky A., Haas P., Boissel N., Metivier F., Randoux C., Kossari N., Guérin A., Geffroy S., Delavaud G., Marin-Esteban V., Glotz D., Charron D., Toubert A., Oxidative stress mediates a reduced expression of the activating receptor NKG2D in NK cells from end-stage renal disease patients. Journal of Immunology 2009 182 3 1696 1705 2-s2.0-63149196735
39. Zhang K., Kaufman R. J., From endoplasmic-reticulum stress to the inflammatory response. Nature 2008 454 7203 455 462 2-s2.0-47949099916 10.1038/nature07203
40. Berrou J., Fougeray S., Venot M., Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes. PLoS ONE 2013 8 e62418
41. Muller L. M. A. J., Gorter K. J., Hak E., Goudzwaard W. L., Schellevis F. G., Hoepelman A. I. M., Rutten G. E. H. M., Increased risk of common infections in patients with type 1 and type 2 diabetes mellitus. Clinical Infectious Diseases 2005 41 3 281 288 2-s2.0-22544478489 10.1086/431587 (Pubitemid 41022101)
42. Lontchi-Yimagou E., Sobngwi E., Matsha T. E., Kengne A. P., Diabetes mellitus and inflammation. Current Diabetes Reports 2013 13 435 444
43. Dandona P., Ghanim H., Bandyopadhyay A., Korzeniewski K., Sia C. L., Dhindsa S., Chaudhuri A., Insulin suppresses endotoxin-induced oxidative, nitrosative, and inflammatory stress in humans. Diabetes Care 2010 33 11 2416 2423 2-s2.0-78649932039 10.2337/dc10-0929
44. Dandona P., Chaudhuri A., Ghanim H., Mohanty P., Insulin as an anti-inflammatory and antiatherogenic modulator. Journal of the American College of Cardiology 2009 53 5 S14 S20 2-s2.0-58549095307 10.1016/j.jacc.2008.10.038
45. Esteve E., Ricart W., Fernández-Real J.-M., Gut microbiota interactions with obesity, insulin resistance and type 2 diabetes: did gut microbiote co-evolve with insulin resistance? Current Opinion in Clinical Nutrition and Metabolic Care 2011 14 5 483 490 2-s2.0-80051710794 10.1097/MCO.0b013e328348c06d
46. Erridge C., Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease. Atherosclerosis 2011 216 1 1 6 2-s2.0-79955531353 10.1016/j.atherosclerosis.2011.02.043
47. Rosa Ramirez S., Ravi Krishna Dasu " M., Toll-like receptors and diabetes complications: recent advances. Current Diabetes Review 2012 8 480 488
48. Balistreri C. R., Candore G., Accardi G., Bova M., Buffa S., Bulati M., Forte G. I., Listi F., Martorana A., Palmeri M., Pellicano M., Vaccarino L., Scola L., Lio D., Colonna-Romano G., Genetics of longevity. Data from the studies on Sicilian centenarians. Immunity & Ageing 2012 9, article 8 2-s2.0-84859933264 10.1186/1742-4933-9-8