-
1
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal,A. et al. (2009) Cancer statistics, 2009. CA Cancer J. Clin., 59, 225-249.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
-
2
-
-
0035473099
-
The epidemiology of UVinduced skin cancer
-
Armstrong,B.K. et al. (2001) The epidemiology of UVinduced skin cancer. J. Photochem. Photobiol. B, 63, 8-18.
-
(2001)
J. Photochem. Photobiol. B
, vol.63
, pp. 8-18
-
-
Armstrong, B.K.1
-
5
-
-
34249808829
-
Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis
-
Cooper,S.J. et al. (2007) Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis. Curr. Cancer Drug Targets, 7, 325-334.
-
(2007)
Curr. Cancer Drug Targets
, vol.7
, pp. 325-334
-
-
Cooper, S.J.1
-
6
-
-
34547541145
-
Ultraviolet radiation and cutaneous carcinogenesis
-
Molho-Pessach,V. et al. (2007) Ultraviolet radiation and cutaneous carcinogenesis. Curr. Probl. Dermatol., 35, 14-27.
-
(2007)
Curr. Probl. Dermatol.
, vol.35
, pp. 14-27
-
-
Molho-Pessach, V.1
-
7
-
-
7444232271
-
Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas
-
Wheeler,D.L. et al. (2004) Protein kinase C epsilon is an endogenous photosensitizer that enhances ultraviolet radiation-induced cutaneous damage and development of squamous cell carcinomas. Cancer Res., 64, 7756-7765.
-
(2004)
Cancer Res.
, vol.64
, pp. 7756-7765
-
-
Wheeler, D.L.1
-
8
-
-
33745220306
-
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents
-
Sandur,S.K. et al. (2006) Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemotherapeutic agents. J. Biol. Chem., 281, 17023-17033.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 17023-17033
-
-
Sandur, S.K.1
-
9
-
-
0032523875
-
Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats
-
Sugie,S. et al. (1998) Inhibitory effects of plumbagin and juglone on azoxymethane-induced intestinal carcinogenesis in rats. Cancer Lett., 127, 177-183.
-
(1998)
Cancer Lett.
, vol.127
, pp. 177-183
-
-
Sugie, S.1
-
10
-
-
33846233374
-
Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells
-
Kuo,P.L. et al. (2006) Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells. Mol. Cancer Ther., 5, 3209-3221.
-
(2006)
Mol. Cancer Ther.
, vol.5
, pp. 3209-3221
-
-
Kuo, P.L.1
-
11
-
-
33745967219
-
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo
-
Hsu,Y.L. et al. (2006) Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo. J. Pharmacol. Exp. Ther., 318, 484-494.
-
(2006)
J. Pharmacol. Exp. Ther.
, vol.318
, pp. 484-494
-
-
Hsu, Y.L.1
-
12
-
-
37049005766
-
Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells
-
Wang,C.C. et al. (2008) Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells. Cancer Lett., 259, 82-98.
-
(2008)
Cancer Lett.
, vol.259
, pp. 82-98
-
-
Wang, C.C.1
-
13
-
-
49549083508
-
Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species
-
Powolny,A.A. et al. (2008) Plumbagin-induced apoptosis in human prostate cancer cells is associated with modulation of cellular redox status and generation of reactive oxygen species. Pharm. Res., 25, 2171-2180.
-
(2008)
Pharm. Res.
, vol.25
, pp. 2171-2180
-
-
Powolny, A.A.1
-
14
-
-
55349147671
-
Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer
-
Aziz,M.H. et al. (2008) Plumbagin, a medicinal plant-derived naphthoquinone, is a novel inhibitor of the growth and invasion of hormone-refractory prostate cancer. Cancer Res., 68, 9024-9032.
-
(2008)
Cancer Res.
, vol.68
, pp. 9024-9032
-
-
Aziz, M.H.1
-
15
-
-
75149117841
-
5-Hydroxy-2-methyl-1,4-naphthoquinone, a vitamin K3 analogue, suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase, SHP-1: potential role in chemosensitization
-
Sandur,S.K. et al. (2010) 5-Hydroxy-2-methyl-1,4-naphthoquinone, a vitamin K3 analogue, suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase, SHP-1: potential role in chemosensitization. Mol. Cancer Res., 8, 107-118.
-
(2010)
Mol. Cancer Res.
, vol.8
, pp. 107-118
-
-
Sandur, S.K.1
-
16
-
-
75949124394
-
Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia
-
Son,T.G. et al. (2010) Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia. J. Neurochem., 112, 1316-1326.
-
(2010)
J. Neurochem.
, vol.112
, pp. 1316-1326
-
-
Son, T.G.1
-
17
-
-
69949169110
-
Inhibition of lysine acetyltransferase KAT3B/p300 activity by a naturally occurring hydroxynaphthoquinone, plumbagin
-
Ravindra,K.C. et al. (2009) Inhibition of lysine acetyltransferase KAT3B/p300 activity by a naturally occurring hydroxynaphthoquinone, plumbagin. J. Biol. Chem., 284, 24453-24464.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 24453-24464
-
-
Ravindra, K.C.1
-
18
-
-
84863021288
-
Plumbagin inhibits tumor angiogenesis and tumor growth through VEGFR2-mediated Ras signaling pathway
-
doi: 10.1111/j.1476-5381.2011.01532.x.[Epub ahead of print]
-
Lai,L. et al. (2011) Plumbagin inhibits tumor angiogenesis and tumor growth through VEGFR2-mediated Ras signaling pathway. Br. J. Pharmacol. doi: 10.1111/j.1476-5381.2011.01532.x.[Epub ahead of print].
-
(2011)
Br. J. Pharmacol.
-
-
Lai, L.1
-
19
-
-
34548787911
-
Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer
-
Aziz,M.H. et al. (2007) Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer. Cancer Res., 67, 8828-8838.
-
(2007)
Cancer Res.
, vol.67
, pp. 8828-8838
-
-
Aziz, M.H.1
-
20
-
-
39149102509
-
Impact of Stat3 activation upon skin biology: a dichotomy of its role between homeostasis and diseases
-
Sano,S. et al. (2008) Impact of Stat3 activation upon skin biology: a dichotomy of its role between homeostasis and diseases. J. Dermatol. Sci., 50, 1-14.
-
(2008)
J. Dermatol. Sci.
, vol.50
, pp. 1-14
-
-
Sano, S.1
-
21
-
-
0027442114
-
Effect of plumbagin on some glucose metabolising enzymes studied in rats in experimental hepatoma
-
Parimala,R. et al. (1993) Effect of plumbagin on some glucose metabolising enzymes studied in rats in experimental hepatoma. Mol. Cell Biochem., 125, 59-63.
-
(1993)
Mol. Cell Biochem.
, vol.125
, pp. 59-63
-
-
Parimala, R.1
-
22
-
-
0020310042
-
Antifertility activity of Plumbago zeylanica Linn. root
-
Azad Chowdhury,A.K. et al. (1982) Antifertility activity of Plumbago zeylanica Linn. root. Indian J. Med. Res., 76 (suppl.), 99-101.
-
(1982)
Indian J. Med. Res.
, vol.76
, Issue.SUPPL.
, pp. 99-101
-
-
Azad Chowdhury, A.K.1
-
23
-
-
4444375662
-
A STAT3 dimer formed by inter-chain disulphide bridging during oxidative stress
-
Li,L. et al. (2004) A STAT3 dimer formed by inter-chain disulphide bridging during oxidative stress. Biochem. Biophys. Res. Commun., 322, 1005-1011.
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.322
, pp. 1005-1011
-
-
Li, L.1
-
24
-
-
1942538505
-
Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis
-
Chan,K.S. et al. (2004) Epidermal growth factor receptor-mediated activation of Stat3 during multistage skin carcinogenesis. Cancer Res., 64, 2382-2389.
-
(2004)
Cancer Res.
, vol.64
, pp. 2382-2389
-
-
Chan, K.S.1
-
25
-
-
0034657958
-
Roles of STAT3 defined by tissue-specific gene targeting
-
Akira,S. (2000) Roles of STAT3 defined by tissue-specific gene targeting. Oncogene, 19, 2607-2611.
-
(2000)
Oncogene
, vol.19
, pp. 2607-2611
-
-
Akira, S.1
-
26
-
-
33847019644
-
Protein kinase C epsilon, which sensitizes skin to sun's UV radiation-induced cutaneous damage and development of squamous cell carcinomas, associates with Stat3
-
Aziz,M.H. et al. (2007) Protein kinase C epsilon, which sensitizes skin to sun's UV radiation-induced cutaneous damage and development of squamous cell carcinomas, associates with Stat3. Cancer Res., 67, 1385-1394.
-
(2007)
Cancer Res.
, vol.67
, pp. 1385-1394
-
-
Aziz, M.H.1
-
27
-
-
41549142664
-
Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents
-
Thasni,K.A. et al. (2008) Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents. Ann. Oncol., 19, 696-705.
-
(2008)
Ann. Oncol.
, vol.19
, pp. 696-705
-
-
Thasni, K.A.1
-
28
-
-
4043159799
-
Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells
-
Srinivas,P. et al. (2004) Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells. Mol. Carcinog., 40, 201-211.
-
(2004)
Mol. Carcinog.
, vol.40
, pp. 201-211
-
-
Srinivas, P.1
-
29
-
-
57349119169
-
Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2
-
Ahmad,A. et al. (2008) Plumbagin-induced apoptosis of human breast cancer cells is mediated by inactivation of NF-kappaB and Bcl-2. J. Cell Biochem., 105, 1461-1471.
-
(2008)
J. Cell Biochem.
, vol.105
, pp. 1461-1471
-
-
Ahmad, A.1
-
30
-
-
34548414657
-
Induction of apoptosis by plumbagin through reactive oxygen species-mediated inhibition of topoisomerase II
-
Kawiak,A. et al. (2007) Induction of apoptosis by plumbagin through reactive oxygen species-mediated inhibition of topoisomerase II. Toxicol. Appl. Pharmacol., 223, 267-276.
-
(2007)
Toxicol. Appl. Pharmacol.
, vol.223
, pp. 267-276
-
-
Kawiak, A.1
-
31
-
-
27544437494
-
Epigallocatechin-3-gallate inhibits photocarcinogenesis through inhibition of angiogenic factors and activation of CD8+ T cells in tumors
-
Mantena,S.K. et al. (2005) Epigallocatechin-3-gallate inhibits photocarcinogenesis through inhibition of angiogenic factors and activation of CD8+ T cells in tumors. Photochem. Photobiol., 81, 1174-1179.
-
(2005)
Photochem. Photobiol.
, vol.81
, pp. 1174-1179
-
-
Mantena, S.K.1
-
32
-
-
21744443080
-
Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease?
-
Aziz,M.H. et al. (2005) Chemoprevention of skin cancer by grape constituent resveratrol: relevance to human disease? FASEB J., 19, 1193-1195.
-
(2005)
FASEB J.
, vol.19
, pp. 1193-1195
-
-
Aziz, M.H.1
-
33
-
-
4344639798
-
Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling
-
Mallikarjuna,G. et al. (2004) Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling. Cancer Res., 64, 6349-6356.
-
(2004)
Cancer Res.
, vol.64
, pp. 6349-6356
-
-
Mallikarjuna, G.1
-
34
-
-
79960303808
-
Perspectives on medicinal properties of plumbagin and its analogs
-
[Epub ahead of print]
-
Padhye,S. et al. (2010) Perspectives on medicinal properties of plumbagin and its analogs. Med. Res. Rev., 9. [Epub ahead of print].
-
(2010)
Med. Res. Rev.
, vol.9
-
-
Padhye, S.1
|