Krüppel-like factor 4 regulates B cell number and activation-induced B cell proliferation

Journal of Immunology

Volumn 179, Issue 7, 2007, Pages 4679-4684

  Klaewsongkram, Jettanong ^a,c   Yang, Yinhua ^a   Golech, Susanne ^a   Katz, Jonathan ^b   Kaestner, Klaus H ^b   Weng, Nan Ping ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

BREAKPOINT CLUSTER REGION PROTEIN; CD40 ANTIGEN; CYCLIN D2; KRUPPEL LIKE FACTOR 4;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; B LYMPHOCYTE ACTIVATION; BONE MARROW CELL; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL DIVISION; CELL MATURATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; SPLEEN CELL; STEM CELL;

ANIMALS; B-LYMPHOCYTES; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CYCLIN D2; CYCLINS; GENE EXPRESSION REGULATION; KRUPPEL-LIKE TRANSCRIPTION FACTORS; LYMPHOCYTE ACTIVATION; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SPLEEN;

EID: 40149094715     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.179.7.4679     Document Type: Article

References (20)

1. Banchereau, J., F. Bazan, D. Blanchard, F. Briere, J. P. Galizzi, C. Van Kooten, Y. J. Liu, F. Rousset, and S. Saeland. 1994. The CD40 antigen and its ligand. Annu. Rev. Immunol. 12: 881-922.
2. Piatelli, M. J., D. Tanguay, T. L. Rothstein, and T. C. Chiles. 2003. Cell cycle control mechanisms in B-1 and B-2 lymphoid subsets. Immunol. Res. 27: 31-52.
3. Chiles, T. C. 2004. Regulation and function of cyclin D2 in B lymphocyte subsets. J. Immunol. 173: 2901-2907.
4. Mohamedali, A., I. Soeiro, N. C. Lea, J. Glassford, L. Banerji, G. J. Mufti, E. W. Lam, and N. S. Thomas. 2003. Cyclin D2 controls B cell progenitor numbers. J. Leukocyte Biol. 74: 1139-1143.
5. Solvason, N., W. W. Wu, D. Parry, D. Mahony, E. W. Lam, J. Glassford, G. G. Klaus, P. Sicinski, R. Weinberg, Y. J. Liu, et al. 2000. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development. Int. Immunol. 12: 631-638.
6. Dai, X., and J. A. Segre. 2004. Transcriptional control of epidermal specification and differentiation. Curr. Opin. Genet. Dev. 14: 485-491.
7. 1/S progression of the cell cycle. J. Biol. Chem. 276: 30423-30428.
8. Chen, X., E. M. Whitney, S. Y. Gao, and V. W. Yang. 2003. Transcriptional profiling of Kruppel-like factor 4 reveals a function in cell cycle regulation and epithelial differentiation. J. Mol. Biol. 326: 665-677.
9. Rowland, B. D., and D. S. Peeper. 2006. KLF4, p21 and context-dependent opposing forces in cancer. Nat. Rev. Cancer 6: 11-23.
10. Rowland, B. D., R. Bernards, and D. S. Peeper. 2005. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat. Cell. Biol. 7: 1074-1082.
11. Kharas, M. G., I. Yusuf, V. M. Scarfone, V. W. Yang, J. A. Segre, C. S. Huettner, and D. A. Fruman. 2007. KLF4 suppresses transformation of pre-B cells by ABL oncogenes. Blood 109: 747-755.
12. Katz, J. P., N. Perreault, B. G. Goldstein, C. S. Lee, P. A. Labosky, V. W. Yang, and K. H. Kaestner. 2002. The zinc-finger transcription factor Klf4 is required for terminal differentiation of goblet cells in the colon. Development 129: 2619-2628.
13. Rickert, R. C., J. Roes, and K. Rajewsky. 1997. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 25: 1317-1318.
14. + T cell response. Blood 108: 3363-3370.
15. Dang, D. T., J. Pevsner, and V. W. Yang. 2000. The biology of the mammalian Kruppel-like family of transcription factors. Int. J. Biochem. Cell. Biol. 32: 1103-1121.
16. Shields, J. M., and V. W. Yang. 1998. Identification of the DNA sequence that interacts with the gut-enriched Kruppel-like factor. Nucleic Acids Res. 26: 796-802.
17. Gaudin, E., M. Rosado, F. Agenes, A. McLean, and A. A. Freitas. 2004. B-cell homeostasis, competition, resources, and positive selection by self-antigens. Immunol. Rev. 197: 102-115.
18. Mohamedali, A., I. Soeiro, N. C. Lea, J. Glassford, L. Banerji, G. J. Mufti, E. W. Lam, and N. S. Thomas. 2003. Cyclin D2 controls B cell progenitor numbers. J. Leukocyte Biol. 74: 1139-1143.
19. Solvason, N., W. W. Wu, D. Parry, D. Mahony, E. W. Lam, J. Glassford, G. G. Klaus, P. Sicinski, R. Weinberg, Y. J. Liu, et al. 2000. Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development. Int. Immunol. 12: 631-638.
20. Rowland, B. D., R. Bernards, and D. S. Peeper. 2005. The KLF4 tumour suppressor is a transcriptional repressor of p53 that acts as a context-dependent oncogene. Nat. Cell. Biol. 7: 1074-1082.