Noninvasive tumor hypoxia measurement using magnetic resonance imaging in murine U87 glioma xenografts and in patients with glioblastoma

Magnetic Resonance in Medicine

Volumn 71, Issue 5, 2014, Pages 1854-1862

  Linnik, Inna V ^a   Scott, Marietta L J ^b   Holliday, Katherine F ^a   Woodhouse, Neil ^b   Waterton, John C ^a,b   O'Connor, James P B ^a   Barjat, Hervé ^b   Liess, Carsten ^b   Ulloa, Jose ^b,c   Young, Helen ^b   Dive, Caroline ^d   Hodgkinson, Cassandra L ^d   Ward, Tim ^d   Roberts, Darren ^d   Mills, Samantha J ^a   Thompson, Gerard ^a   Buonaccorsi, Giovanni A ^a,c   Cheung, Susan ^a   Jackson, Alan ^a   Naish, Josephine H ^a   Parker, Geoff J M ^a,c   more..

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

^c Bioxydyn Limited   (United Kingdom)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

hypoxia; magnetic resonance imaging; oxygen enhanced MRI; oxygenation

Indexed keywords

BIOMARKERS; MAGNETISM; OXYGENATION; RESONANCE; TUMORS;

AREA UNDER THE CURVES; CLINICAL BIOMARKERS; CLINICAL EVALUATION; DYNAMIC CONTRAST ENHANCED MRI; GLIOBLASTOMA MULTIFORME; HYPOXIA; NEGATIVE CORRELATION; POSITIVE CORRELATIONS;

MAGNETIC RESONANCE IMAGING;

CD31 ANTIGEN; GADODIAMIDE; GADOLINIUM PENTETATE MEGLUMINE; OXYGEN; PIMONIDAZOLE; TUMOR MARKER;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; FEMALE; GLIOBLASTOMA; GLIOMA; HEMISPHERE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYPOXIA; MALE; MOUSE; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OXYGEN BREATHING; TUMOR HYPOXIA; TUMOR NECROSIS; TUMOR VOLUME; ANIMAL; BRAIN TUMOR; CELL HYPOXIA; METABOLISM; NUDE MOUSE; OXIMETRY; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; TUMOR CELL LINE;

ANIMALS; BRAIN NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; FEMALE; GLIOBLASTOMA; GLIOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MICE; MICE, NUDE; OXIMETRY; OXYGEN; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TISSUE DISTRIBUTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84899429750     PISSN: 07403194     EISSN: 15222594     Source Type: Journal    
DOI: 10.1002/mrm.24826     Document Type: Article

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