Preliminary Study of Oxygen-Enhanced Longitudinal Relaxation in MRI: A Potential Novel Biomarker of Oxygenation Changes in Solid Tumors

International Journal of Radiation Oncology Biology Physics

Volumn 75, Issue 4, 2009, Pages 1209-1215

  O'Connor, James P B ^a,b   Naish, Josephine H ^a   Parker, Geoff J M ^a   Waterton, John C ^a,c   Watson, Yvonne ^a   Jayson, Gordon C ^b   Buonaccorsi, Giovanni A ^a   Cheung, Sue ^a   Buckley, David L ^a   McGrath, Deirdre M ^a   West, Catharine M L ^a   Davidson, Susan E ^b   Roberts, Caleb ^a   Mills, Samantha J ^a   Mitchell, Claire L ^b   Hope, Lynn ^b   Ton, N Chan ^b   Jackson, Alan ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c ASTRAZENECA   (United Kingdom)

Author keywords

Biomarker; Longitudinal relaxation rate (R1); MRI; Neoplasm; Oxygen

Indexed keywords

BLOOD OXYGENATION; DYNAMIC CONTRAST ENHANCED MRI; HEALTHY TISSUES; HEPATOCELLULAR; LONGITUDINAL RELAXATION; LONGITUDINAL RELAXATION RATE (R1); LOW AREA; MRI; NONINVASIVE METHODS; OXYGEN CONCENTRATIONS; OXYGEN DELIVERY; PROPORTIONAL CHANGE; RECURRENT TUMORS; SOLID TUMORS; SPATIAL DISTRIBUTION; SPATIAL MAPPING; TUMOR HYPOXIA; TUMOR OXYGENATION;

CONCENTRATION (PROCESS); GADOLINIUM; MAGNETIC RESONANCE IMAGING; ONCOLOGY; OXYGENATION; OXYGENATORS; RESONANCE; SIZE DISTRIBUTION; TUMORS;

OXYGEN;

BIOLOGICAL MARKER; GADODIAMIDE; CONTRAST MEDIUM; DIAGNOSTIC AGENT; GADOLINIUM; OXYGEN;

ABDOMINAL CANCER; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; BLOOD OXYGENATION; CLINICAL ARTICLE; COLORECTAL CARCINOMA; DRUG UPTAKE; FEMALE; HUMAN; LIVER CELL CARCINOMA; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; OVARY CARCINOMA; OXYGENATION; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECURRENT CANCER; SOLID TUMOR; UTERINE CERVIX CANCER; ABDOMINAL TUMOR; ADENOCARCINOMA; CELL HYPOXIA; LIVER TUMOR; METABOLISM; METHODOLOGY; MIDDLE AGED; OMENTUM; OVARY TUMOR; PELVIS TUMOR; PERITONEUM TUMOR; PHYSIOLOGY; SQUAMOUS CELL CARCINOMA;

ABDOMINAL NEOPLASMS; ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; CARCINOMA, HEPATOCELLULAR; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; CONTRAST MEDIA; FEMALE; GADOLINIUM; HUMANS; LIVER NEOPLASMS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OMENTUM; OVARIAN NEOPLASMS; OXYGEN; PELVIC NEOPLASMS; PERITONEAL NEOPLASMS;

EID: 70449698809     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2008.12.040     Document Type: Article

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