Effects of hematocrit and oxygen saturation level on blood spin-lattice relaxation

Magnetic Resonance in Medicine

Volumn 49, Issue 3, 2003, Pages 568-571

  Silvennoinen, M Johanna ^a   Kettunen, Mikko I ^a   Kauppinen, Risto A ^a,b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Blood; Oxygen saturation; Quantification; T1

Indexed keywords

DISSOLVED OXYGEN;

ARTERIAL SPIN LABELING; BLOOD PLASMA; KEY FACTORS; LINEAR DEPENDENCY; OXYGEN SATURATION; OXYGEN SATURATION LEVELS; PHYSIOLOGICAL RANGE; QUANTIFICATION;

BLOOD;

ANIMAL TISSUE; ARTICLE; BLOOD FLOW; BODY TEMPERATURE; CONTROLLED STUDY; ENERGY TRANSFER; GAS EXCHANGE; HEMATOCRIT; MACROMOLECULE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXYGEN SATURATION; PROTEIN CONTENT; SPIN LABELING; VISCOSITY;

EID: 0037371755     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.10370     Document Type: Article

References (20)

1. Ogawa S, Menon RS, Tank DW, Kim S-G, Merkle H, Ellerman JM, Ugurbil K. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging: a comparison of signal characteristics with a biophysical model. Biophys J 1993;64:803-812.
2. Haacke EM, Lai S, Reichenbach JR, Kuppusamy K, Hoogenraad FGC, Tackeichi H, Lin W. In vivo measurement of blood oxygen saturation using magnetic resonance imaging: a direct validation of the blood oxygen level-dependent concept in functional brain imaging. Hum Brain Map 1997;5:341-346.
3. 2: increased precision and validation of principle. Magn Reson Med 2001;46:282-291.
4. 1-weighted echo planar imaging. Magn Reson Med 1995;34:878-887.
5. Silva AC, Zhang W, Williams DS, Koretsky AP. Estimation of water extraction fractions in rat brain using magnetic resonance measurement of perfusion with arterial spin labeling. Magn Reson Med 1997;37:58-68.
6. Koenig SH, Brown III RD, Ugolini R. A unified view of relaxation in protein solutions and tissue, including hydration and magnetization transfer. Magn Reson Med 1993;29:77-83.
7. Wang D, Kreutzer U, Chung Y, Jue T. Myoglobin and hemoglobin rotational diffusion in the cell. Biophys J 1997;73:2764-2770.
8. Chiarotti G, Christiani G, Giulotto L. Proton relaxation in pure liquids and in liquids containing paramagnetic gases in solution. Nuovo Cimento 1955;1:863-873.
9. Jiao X, Bryant RG. Noninvasive measurement of protein concentration. Magn Reson Med 1996;35:159-161.
10. Bryant RG, Marill K, Blackmore C, Francis C. Magnetic relaxation in blood and blood clots. Magn Reson Med 1990;13:133-144.
11. Leenders KL, Perani D, Lammertsma AA, Heather JD, Buckingham P, Healy MJR, Gibbs JM, Wise RJS, Hatazawa J, Herold S, Beaney RP, Brooks DJ, Spinks T, Rhodes C, Frackowiak RSJ, Jones T. Cerebral blood flow, blood volume and oxygen utilization: normal values and effect of age. Brain 1990;113:27-47.
12. Thulborn KR, Waterton JC, Matthews PM, Radda GK. Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim Biophys Acta 1982;714:265-270.
13. 1p relaxation in rat brain. Magn Reson Med 2002;48:470-477.
14. 2 in the isolated, perfused rabbit heart at 4.7T. Magn Reson Med 1995;34:623-627.
15. Rostrup E, Larsson HBW, Toft PB, Garde K, Henriksen O. Signal changes in gradient echo images of human brain induced by hypo- and hyperoxia. NMR Biomed 1995;8:41-47.
16. Herbst MD, Goldstein JH. A review of water diffusion measurement by NMR in human red blood cells. Am J Physiol 1989;256:C1097-C1104.
17. Wright GA, Hu BS, Macovski A. Estimating oxygen saturation of blood in vivo with MR imaging at 1.5T. J Magn Reson Imag 1991;1:275-283.
18. Solomon I. Relaxation processes in a system of two spins. Phys Rev 1955;99:559-565.
19. Lauffer RB, Brady TJ. Preparation and water relaxation properties of proteins labeled with paramagnetic metal chelates. Magn Reson Imag 1985;3:11-16.
20. Yang Y, Frank JA, Hou L, Ye FQ, McLaughlin AC, Duyn JH. Multislice imaging of quantitative cerebral perfusion with pulsed arterial spin labeling. Magn Reson Med 1998;39:825-832.