Genetic diversity of Salp15 in the Ixodes ricinus complex (Acari: Ixodidae)

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Wang, Xin ^a,b   Huang, Yong ^a   Niu, Si Bo ^c   Jiang, Bao Gui ^a   Jia, Na ^a   Van Der Geest, Leo ^d   Ni, Xue Bing ^a   Sun, Yi ^a,b   Cao, Wu Chun ^a  

^a BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^b Wenzhou Municipal Center for Disease Control and Prevention   (China)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN SALP15; SALIVA PROTEIN; UNCLASSIFIED DRUG; SALP15 PROTEIN, IXODES SCAPULARIS;

AMINO TERMINAL SEQUENCE; ARTICLE; CHINA; DEVELOPMENTAL STAGE; GENE EXPRESSION; GENETIC CONSERVATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; IXODES PERSULCATUS; IXODES RICINUS; IXODES SINENSIS; LARVA; LYME DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; NYMPH; PHYLOGENY; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PURIFICATION; SALP15 GENE; ANIMAL; GENETICS; IXODES; TRANSMISSION;

ANIMALS; GENETIC VARIATION; IXODES; LYME DISEASE; SALIVARY PROTEINS AND PEPTIDES;

EID: 84899412196     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0094131     Document Type: Article

References (46)

1. Hovius JW, Levi M, Fikrig E (2008) Salivating for knowledge: potential pharmacological agents in tick saliva. PLOS Med5:e43
2. Dai J, Wang P, Adusumilli S, Booth CJ, Narasimhan S, et al. (2009) Antibodies against a tick protein, Salp15, protect mice from the Lyme disease agent. Cell Host Microbe 6: 482-492.
3. Nene V, Lee D, Kang'a S, Skilton R, Shah T, et al. (2004) Genes transcribed in the salivary glands of female Rhipicephalus appendiculatus ticks infected with Theileria parva. Insect Biochem Mol Biol 34: 1117-1128.
4. Jordan SP, Waxman L, Smith DE, Vlasuk GP (1990) Tick anticoagulant peptide: kinetic analysis of the recombinant inhibitor with blood coagulation factor Xa. Biochemistry 29: 11095-11100.
5. Waxman L, Smith DE, Arcuri KE, Vlasuk GP (1990) Tick anticoagulant peptide (TAP) is a novel inhibitor of blood coagulation factor Xa. Science 248: 593-596.
6. Wang H, Nuttall PA (1994) Excretion of host immunoglobulin in tick saliva and detection of IgG-binding proteins in tick hemolymph and salivary glands. Parasitology 109: 525-530.
7. Wang H, Nuttall PA (1995) Immunoglobulin-G binding proteins in the Ixodid ticks, Rhipicephalus appendiculatus, Amblyomma variegatum and Ixodes hexagonus. Parasitology 111: 161-165.
8. Rechav Y, Nuttall PA (2000) The effect of male ticks on the feeding performance of immature stages of Rhipicephalus sanguineus and Amblyomma americanum (Acari: Ixodidae). Experiemtal and Applied Acarology 24:569-578.
9. Valenzuela JG, Charlab R, Mather TN, Ribeiro JM (2000) Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis. J Biol Chem 275: 18717-18723.
10. Gillespie RD, Dolan MC, Piesman J, Titus RG (2001) Identification of an IL-2 binding protein in the saliva of the Lyme disease vector tick, Ixodes scapularis. J Immunol 166: 4319-4326.
11. Hannier S, Liversidge J, Sternberg JM, Bowman AS (2004) Characterization of the B-cell inhibitory protein factor in Ixodes ricinus tick saliva: a potential role in enhanced Borrelia burgdoferi transmission. Immunology 113: 401-408.
12. Narasimhan S, Montgomery RR, DePonte K, Tschudi C, Marcantonio N, et al. (2004) Disruption of Ixodes scapularis anticoagulation by using RNA interference. Proc Natl Acad Sci U S A 101: 1141-1146.
13. Tyson K, Elkins C, Patterson H, Fikrig E, de Silva A (2007) Biochemical and functional characterization of Salp20, an Ixodes scapularis tick salivary protein that inhibits the complement pathway. Insect Mol Biol 16: 469-479.
14. Das S, Banerjee G, DePonte K, Marcantonio N, Kantor FS, et al. (2001) Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands. J Infect Dis 184: 1056-1064
15. Liu L, Narasimhan S, Dai J, Zhang L, Cheng G, et al. (2011) Ixodes scapularis salivary gland protein P11 facilitates migration of Anaplasma phagocytophilum from the tick gut to salivary glands. EMBO Rep 12: 1196-1203.
16. Wang G, van Dam AP, Schwartz I, Dankert J (1999) Molecular typing of Borrelia burgdorferi sensulato: taxonomic, epidemiological, and clinical implications. Clin Microbiol Rev 12: 633-653.
17. Alao OR, Decker CF (2012) Lyme disease. Dis Mon. 58: : 335-345.
18. Hovius JW, Ramamoorthi N, Van't Veer C, de Groot KA, Nijhof AM, et al. (2007) Identification of Salp15 homologues in Ixodes ricinus ticks. Vector Borne Zoonotic Dis 7: 296-303.
19. Hao Q, Hou X, Geng Z, Wan K (2011) Distribution of Borrelia burgdorferi sensu lato in China. J Clin Microbiol. 49: 647-650
20. Xu G, Fang QQ, Keirans JE, Durden LA (2003) Molecular phylogenetic analyses indicate that the Ixodes ricinus complex is a paraphyletic group. J Parasitol. 89: 452-457.
21. Filippova NA (1991) A hypothesis for the palaeogenesis of the distribution of the main vectors for Lyme disease. In Modern acarology, vol. 1, F. Dusbabek and V. Bukva (eds.). Academia, The Hague, The Netherlands p. 109-118.
22. Oliver JH (1996) Lyme borreliosis in the southern United States: a review. J Parasitol 82(6):926-935.
23. Burgdorfer W (1989) Vector/host relationships of the Lyme disease spirochete, Borrelia burgdorferi. Rheum Dis Clin North Am 15: 775-787.
24. Ramamoorthi N, Narasimhan S, Pal U, Bao F, Yang XF, et al. (2005) The Lyme disease agent exploits a tick protein to infect the mammalian host. Nature 436: 573-577.
25. Titus RG, Bishop JV, Mejia JS (2006) The immunomodulatory factors of arthropod saliva and the potential for these factors to serve as vaccine targets to prevent pathogen transmission. Parasit Immunol 28: 131-141.
26. Hovius JW, Schuijt TJ, de Groot KA, Roelofs JJ, Oei GA, et al. (2008) Preferential protection of Borrelia burgdorferi sensu stricto by a Salp15 homologue in Ixodes ricinus saliva. J Infect Dis 198: 1189-1197.
27. Hojgaard A, Biketov SF, Shtannikov AV, Zeidner NS, Piesman J (2009) Molecular identification of Salp15, a key salivary gland protein in the transmission of lyme disease spirochetes, from Ixodes persulcatus and Ixodes pacificus (Acari: Ixodidae) J Med Entomol 46: 1458-1463.
28. Mori A, Konnai S, Yamada S, Hidano A, Murase Y, et al. (2010) Two novel Salp15-like immunosuppressant genes from salivary glands of Ixodes persulcatus Schulze tick. Insect Mol Biol 19: 359-365
29. Sun Y, Xu RM, Cao WC (2003) Ixodes sinensis: competence as a vector to transmit the Lyme disease spirochete Borrelia garinii. Vector Borne Zoonotic Dis 3: : 39-44.
30. Liu X, Wu J, Wang J, Liu X, Zhao S, et al. (2009) WebLab: a data-centric, knowledge-sharing bioinformatic platform. Nucleic Acids Res 37(Web Server issue):W33-39.
31. Petersen TN, Brunak S, von Heijne G, Nielsen H (2011) SignalP 4.0: discriminating signal peptides from transmembrane regions. Nat Methods 8: 785-786
32. Larkin MA, Blackshields G, Brown NP, Chenna R, McGettigan PA, et al. (2007) Clustal W and Clustal X version 2.0. Bioinformatics 23: 2947-2948.
33. Saitou N, Nei M (1987) The neighbor-joining method: A new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4: 406-425.
34. Tamura K, Dudley J, Nei M, Kumar S (2007) MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) software version 4.0. Molecular Biology and Evolution 24: 1596-1599.
35. Jones DT, Taylor WR, Thornton JM (1992) The rapid generation of mutation data matrices from protein sequences. Comput Appl Biosci 8: 275-282.
36. Anguita J, Ramamoorthi N, Hovius JW, Das S Thomas V, et al. (2002) Salp15, an Ixodes scapularis salivary protein, inhibits CD4(+) T cell activation. Immunity 16: 849-859
37. Schwarz RF, Fletcher W, Förster F, Merget B, Wolf M, et al. (2010) Evolutionary distances in the twilight zone-a rational kernel approach. PLOS One 5:e15788.
38. Garg R, Juncadella IJ, Ramamoorthi N, Ashish, Ananthanarayanan SK, et al. (2006) Cutting edge: CD4 is the receptor for the tick saliva immunosuppressor, Salp15. J Immunol 177: 6579-6583.
39. Juncadella IJ (2008) Functional analysis of the salivary protein, Salp15. [Doctoral dissertation] Electronic Doctoral Dissertations for U. Mass Amherst Paper AAI3329956.
40. Juncadella IJ, Garg R, Ananthnarayanan SK, Yengo CM, Anguita J (2007) T-cell signaling pathways inhibited by the tick saliva immunosuppressor, Salp15. FEMS Immunol Med Microbiol 49: 433-438.
41. Cavassani KA, Aliberti JC, Dias AR, Silva JS, Ferreira BR (2005) Tick saliva inhibits differentiation, maturation and function of murine bone-marrow-derived dendritic cells. Immunology 114: 235-245.
42. Hovius JW, de Jong MA, den Dunnen J, Litjens M, Fikrig E, et al. (2008) Salp15 binding to DC-SIGN inhibits cytokine expression by impairing both nucleosome remodeling and mRNA stabilization. PLoS Pathog 4:e31.
43. Schuijt TJ, Hovius JW, van Burgel ND, Ramamoorthi N, Fikrig E, et al. (2008) The tick salivary protein Salp15 inhibits the killing of serum-sensitive Borrelia burgdorferi sensu lato isolates 76: 2888-2894.
44. Wu J, Helftenbein G, Koslowski M, Sahin U, Tureci O (2006) Identification of new claudin family members by a novel PSI-BLAST based approach with enhanced specificity. Proteins 65: 808-815.
45. Hovius JW, Ramamoorthi N, Van't Veer C, de Groot KA, Nijhof AM, et al. (2007) Identification of Salp15 homologues in Ixodes ricinus ticks. Vector Borne Zoonotic Dis 7: 296-303
46. Schuijt TJ, Hovius JW, van der Poll T, van Dam AP, Fikrig E (2011) Lyme borreliosis vaccination: the facts, the challenge, the future. Trends Parasitol 27: 40-47.