Effects of cigarette smoke on Toll-like receptor (TLR) activation of chronic obstructive pulmonary disease (COPD) macrophages

Clinical and Experimental Immunology

Volumn 176, Issue 3, 2014, Pages 461-472

  Metcalfe, H J ^a   Lea, S ^a   Hughes, D ^a   Khalaf, R ^a   Abbott Banner, K ^b,c   Singh, D ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b Novartis Inst of BioMedical Res   (United Kingdom)

^c Verona Pharma Plc   (United Kingdom)

Author keywords

Bacteria; Cigarette smoke; COPD macrophage; Immune response; TLR

Indexed keywords

CIGARETTE SMOKE; CORTICOSTEROID; FLAGELLIN; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; RANTES; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION; HAEMOPHILUS INFLUENZAE; HUMAN; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MALE; MIDDLE AGED; NEUTROPHIL CHEMOTAXIS; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

BACTERIA; CIGARETTE SMOKE; COPD MACROPHAGE; IMMUNE RESPONSE; TLR;

AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CYTOKINES; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HAEMOPHILUS INFECTIONS; HUMANS; INTERLEUKIN-8; MACROPHAGE ACTIVATION; MACROPHAGES; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; SMOKING; TOLL-LIKE RECEPTORS; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84899093006     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12289     Document Type: Article

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