-
1
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman, J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med., 1, 27-31.
-
(1995)
Nat. Med.
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
2
-
-
0016218630
-
Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation
-
Liotta, L.A., Kleinerman, J. and Saidel, G.M. (1974) Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res., 34, 997-1004.
-
(1974)
Cancer Res.
, vol.34
, pp. 997-1004
-
-
Liotta, L.A.1
Kleinerman, J.2
Saidel, G.M.3
-
3
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman, J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl Cancer Inst., 82, 4-6. (Pubitemid 20020880
-
(1990)
Journal of the National Cancer Institute
, vol.82
, Issue.1
, pp. 4-6
-
-
Folkman, J.1
-
4
-
-
0037967272
-
Tumorigenesis and the angiogenic switch
-
Bergers, G. and Benjamin, L.E. (2003) Tumorigenesis and the angiogenic switch. Nat. Rev. Cancer, 3, 401-410.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 401-410
-
-
Bergers, G.1
Benjamin, L.E.2
-
5
-
-
0028846008
-
VEGF-mediated tumour angiogenesis: A new target for cancer therapy
-
Martiny-Baron, G. and Marme, D. (1995) VEGF-mediated tumour angiogenesis: A new target for cancer therapy. Curr. Opin. Biotechnol., 6, 675-680.
-
(1995)
Curr. Opin. Biotechnol.
, vol.6
, pp. 675-680
-
-
Martiny-Baron, G.1
Marme, D.2
-
6
-
-
0036984640
-
Role of angiogenesis in tumor growth and metastasis
-
Folkman, J. (2002) Role of angiogenesis in tumor growth and metastasis. Semin. Oncol., 29, 15-18.
-
(2002)
Semin. Oncol.
, vol.29
, pp. 15-18
-
-
Folkman, J.1
-
7
-
-
0036984738
-
Tumor angiogenesis and accessibility: Role of vascular endothelial growth factor
-
Jain, R.K. (2002) Tumor angiogenesis and accessibility: Role of vascular endothelial growth factor. Semin. Oncol., 29, 3-9.
-
(2002)
Semin. Oncol.
, vol.29
, pp. 3-9
-
-
Jain, R.K.1
-
8
-
-
0024370274
-
Recent developments in the cell biology of basic fibroblast growth factor
-
Rifkin, D.B. and Moscatelli, D. (1989) Recent developments in the cell biology of basic fibroblast growth factor. J. Cell Biol., 109, 1-6. (Pubitemid 19180114
-
(1989)
Journal of Cell Biology
, vol.109
, Issue.1
, pp. 1-6
-
-
Rifkin, D.B.1
Moscatelli, D.2
-
9
-
-
0027363217
-
Epidermal growth factor receptor-mediated autocrine and paracrine stimulation of human transitional cell carcinoma
-
Gleave, M.E., Hsieh, J.T., Wu, H.C., Hong, S.J., Zhau, H.E., Guthrie, P.D. and Chung, L.W. (1993) Epidermal growth factor receptor-mediated autocrine and paracrine stimulation of human transitional cell carcinoma. Cancer Res., 53, 5300-5307. (Pubitemid 23333403
-
(1993)
Cancer Research
, vol.53
, Issue.21
, pp. 5300-5307
-
-
Gleave, M.E.1
Hsieh, J.-T.2
Wu, H.-C.3
Hong, S.-J.4
Zhau, H.E.5
Guthrie, P.D.6
Chung, L.W.K.7
-
10
-
-
0028139239
-
Vascular endothelial growth factor platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro
-
Nicosia, R.F., Nicosia, S.V. and Smith, M. (1994) Vascular endothelial growth factor, platelet-derived growth factor, and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro. Am. J. Pathol., 145, 1023-1029.
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1023-1029
-
-
Nicosia, R.F.1
Nicosia, S.V.2
Smith, M.3
-
11
-
-
0030460424
-
Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-Trap expression cloning
-
DOI 10.1016/S0092-8674(00)81812-7
-
Davis, S., Aldrich, T.H., Jones, P.F., Acheson, A., Compton, D.L., Jain, V., Ryan, T.E., Bruno, J., Radziejewski, C., Maisonpierre, P.C. et al. (1996) Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-Trap expression cloning. Cell, 87, 1161-1169. (Pubitemid 27010100
-
(1996)
Cell
, vol.87
, Issue.7
, pp. 1161-1169
-
-
Davis, S.1
Aldrich, T.H.2
Jones, P.F.3
Acheson, A.4
Compton, D.L.5
Jain, V.6
Ryan, T.E.7
Bruno, J.8
Radziejewski, C.9
Maisonpierre, P.C.10
Yancopoulos, G.D.11
-
12
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
DOI 10.1126/science.277.5322.55
-
Maisonpierre, P.C., Suri, C., Jones, P.F., Bartunkova, S., Wiegand, S.J., Radziejewski, C., Compton, D., McClain, J., Aldrich, T.H., Papadopoulos, N. et al. (1997) Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science, 277, 55-60. (Pubitemid 27450643
-
(1997)
Science
, vol.277
, Issue.5322
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
Bartunkova, S.4
Wiegand, S.J.5
Radziejewski, C.6
Compton, D.7
McClain, J.8
Aldrich, T.H.9
Papadopoulos, N.10
Daly, T.J.11
Davis, S.12
Sato, T.N.13
Yancopoulos, G.D.14
-
13
-
-
0036491615
-
VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic cell carcinogenesis
-
DOI 10.1016/S1535-6108(02)00031-4
-
Inoue, M., Hager, J.H., Ferrara, N., Gerber, H.P. and Hanahan, D. (2002) VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis. Cancer Cell, 1, 193-202. (Pubitemid 41039165
-
(2002)
Cancer Cell
, vol.1
, Issue.2
, pp. 193-202
-
-
Inoue, M.1
Hager, J.H.2
Ferrara, N.3
Gerber, H.-P.4
Hanahan, D.5
-
14
-
-
0029021904
-
Endothelial receptor tyrosine kinases involved in angiogenesis
-
Mustonen, T. and Alitalo, K. (1995) Endothelial receptor tyrosine kinases involved in angiogenesis. J. Cell Biol., 129, 895-898.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 895-898
-
-
Mustonen, T.1
Alitalo, K.2
-
15
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara, N., Gerber, H.P. and LeCouter, J. (2003) The biology of VEGF and its receptors. Nat. Med., 9, 669-676.
-
(2003)
Nat. Med.
, vol.9
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
LeCouter, J.3
-
16
-
-
33344474964
-
Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
-
Shibuya, M. and Claesson-Welsh, L. (2006) Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Exp. Cell Res., 312, 549-560.
-
(2006)
Exp. Cell Res.
, vol.312
, pp. 549-560
-
-
Shibuya, M.1
Claesson-Welsh, L.2
-
17
-
-
33646107369
-
VEGF receptor signalling-in control of vascular function
-
Olsson, A.K., Dimberg, A., Kreuger, J. and Claesson-Welsh, L. (2006) VEGF receptor signalling-in control of vascular function. Nat. Rev. Mol. Cell Biol., 7, 359-371.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 359-371
-
-
Olsson, A.K.1
Dimberg, A.2
Kreuger, J.3
Claesson-Welsh, L.4
-
18
-
-
50149083752
-
Mammalian Rho GTPases: New insights into their functions from in vivo studies
-
Heasman, S.J. and Ridley, A.J. (2008) Mammalian Rho GTPases: New insights into their functions from in vivo studies. Nat. Rev. Mol. Cell Biol., 9, 690-701.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 690-701
-
-
Heasman, S.J.1
Ridley, A.J.2
-
19
-
-
84860130221
-
Anti-VEGF/ VEGFR therapy for cancer: Reassessing the target
-
Sitohy, B., Nagy, J.A. and Dvorak, H.F. (2012) Anti-VEGF/ VEGFR therapy for cancer: Reassessing the target. Cancer Res., 72, 1909-1914.
-
(2012)
Cancer Res.
, pp. 72
-
-
Sitohy, B.1
Nagy, J.A.2
Dvorak, H.F.3
-
20
-
-
0034176194
-
G-quadruplex DNA: A potential target for anti-cancer drug design
-
Han, H. and Hurley, L.H. (2000) G-quadruplex DNA: A potential target for anti-cancer drug design. Trends Pharmacol. Sci., 21, 136-142.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 136-142
-
-
Han, H.1
Hurley, L.H.2
-
21
-
-
34548857357
-
Targeting the limitless replicative potential of cancer: The telomerase/telomere pathway
-
Kelland, L. (2007) Targeting the limitless replicative potential of cancer: The telomerase/telomere pathway. Clin. Cancer Res., 13, 4960-4963.
-
(2007)
Clin. Cancer Res.
, vol.13
, pp. 4960-4963
-
-
Kelland, L.1
-
22
-
-
76349122184
-
Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer
-
Neidle, S. (2010) Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer. FEBS J., 277, 1118-1125.
-
(2010)
FEBS J.
, vol.277
, pp. 1118-1125
-
-
Neidle, S.1
-
23
-
-
79953313413
-
Targeting G-quadruplexes in gene promoters: A novel anticancer strategy? Nat
-
Balasubramanian, S., Hurley, L.H. and Neidle, S. (2011) Targeting G-quadruplexes in gene promoters: A novel anticancer strategy? Nat. Rev. Drug. Discov., 10, 261-275.
-
(2011)
Rev. Drug. Discov.
, vol.10
, pp. 261-275
-
-
Balasubramanian, S.1
Hurley, L.H.2
Neidle, S.3
-
24
-
-
84875464903
-
Quantitative visualization of DNA G-quadruplex structures in human cells
-
Biffi, G., Tannahill, D., McCafferty, J. and Balasubramanian, S. (2013) Quantitative visualization of DNA G-quadruplex structures in human cells. Nat. Chem., 5, 182-186.
-
(2013)
Nat. Chem.
, vol.5
, pp. 182-186
-
-
Biffi, G.1
Tannahill, D.2
McCafferty, J.3
Balasubramanian, S.4
-
25
-
-
84877768759
-
G-quadruplex structures are stable and detectable in human genomic DNA
-
Lam, E.Y., Beraldi, D., Tannahill, D. and Balasubramanian, S. (2013) G-quadruplex structures are stable and detectable in human genomic DNA. Nat. Commun., 4, 1796.
-
(2013)
Nat. Commun.
, vol.4
, pp. 1796
-
-
Lam, E.Y.1
Beraldi, D.2
Tannahill, D.3
Balasubramanian, S.4
-
26
-
-
36049045013
-
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect
-
Salvati, E., Leonetti, C., Rizzo, A., Scarsella, M., Mottolese, M., Galati, R., Sperduti, I., Stevens, M.F., D'Incalci, M., Blasco, M. et al. (2007) Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect. J. Clin. Invest., 117, 3236-3247.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3236-3247
-
-
Salvati, E.1
Leonetti, C.2
Rizzo, A.3
Scarsella, M.4
Mottolese, M.5
Galati, R.6
Sperduti, I.7
Stevens, M.F.8
D'Incalci, M.9
Blasco, M.10
-
27
-
-
61349168351
-
A mechanosensitive transcriptional mechanism that controls angiogenesis
-
Mammoto, A., Connor, K.M., Mammoto, T., Yung, C.W., Huh, D., Aderman, C.M., Mostoslavsky, G., Smith, L.E. and Ingber, D.E. (2009) A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature, 457, 1103-1108.
-
(2009)
Nature
, vol.457
, pp. 1103-1108
-
-
Mammoto, A.1
Connor, K.M.2
Mammoto, T.3
Yung, C.W.4
Huh, D.5
Aderman, C.M.6
Mostoslavsky, G.7
Smith, L.E.8
Ingber, D.E.9
-
28
-
-
0037015078
-
Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription
-
Siddiqui-Jain, A., Grand, C.L., Bearss, D.J. and Hurley, L.H. (2002) Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c-MYC transcription. Proc. Natl Acad. Sci. USA, 99, 11593-11598.
-
(2002)
Proc. Natl Acad. Sci. USA
, vol.99
, pp. 11593-11598
-
-
Siddiqui-Jain, A.1
Grand, C.L.2
Bearss, D.J.3
Hurley, L.H.4
-
29
-
-
0037113935
-
Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells
-
Biroccio, A., Benassi, B., Filomeni, G., Amodei, S., Marchini, S., Chiorino, G., Rotilio, G., Zupi, G. and Ciriolo, M.R. (2002) Glutathione influences c-Myc-induced apoptosis in M14 human melanoma cells. J. Biol. Chem., 277, 43763-43770.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43763-43770
-
-
Biroccio, A.1
Benassi, B.2
Filomeni, G.3
Amodei, S.4
Marchini, S.5
Chiorino, G.6
Rotilio, G.7
Zupi, G.8
Ciriolo, M.R.9
-
30
-
-
54249135733
-
Suppression of breast cancer metastasis through the inhibition of VEGFmediated tumor angiogenesis
-
Zhang, J., Lu, A., Beech, D., Jiang, B. and Lu, Y. (2007) Suppression of breast cancer metastasis through the inhibition of VEGFmediated tumor angiogenesis. Cancer Ther., 5, 273-286.
-
(2007)
Cancer Ther.
, vol.5
, pp. 273-286
-
-
Zhang, J.1
Lu, A.2
Beech, D.3
Jiang, B.4
Lu, Y.5
-
31
-
-
0033615966
-
Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
-
Sander, E.E., ten Klooster, J.P., van Delft, S., van der Kammen, R.A. and Collard, J.G. (1999) Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior. J. Cell Biol., 147, 1009-1022.
-
(1999)
J. Cell Biol.
, vol.147
, pp. 1009-1022
-
-
Sander, E.E.1
Ten Klooster, J.P.2
Van Delft, S.3
Van Der Kammen, R.A.4
Collard, J.G.5
-
32
-
-
58149359322
-
G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors
-
Leonetti, C., Scarsella, M., Riggio, G., Rizzo, A., Salvati, E., D'Incalci, M., Staszewsky, L., Frapolli, R., Stevens, M.F., Stoppacciaro, A. et al. (2008) G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors. Clin. Cancer Res., 14, 7284-7291.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 7284-7291
-
-
Leonetti, C.1
Scarsella, M.2
Riggio, G.3
Rizzo, A.4
Salvati, E.5
D'Incalci, M.6
Staszewsky, L.7
Frapolli, R.8
Stevens, M.F.9
Stoppacciaro, A.10
-
33
-
-
33747860882
-
QGRS Mapper: A web-based server for predicting G-quadruplexes in nucleotide sequences
-
WEB. SERV. ISS. DOI 10.1093/nar/gkl253
-
Kikin, O., D'Antonio, L. and Bagga, P.S. (2006) QGRS Mapper: A web-based server for predicting G-quadruplexes in nucleotide sequences. Nucleic Acids Res., 34, W676-W682. (Pubitemid 44529856
-
(2006)
Nucleic Acids Research
, vol.34
-
-
Kikin, O.1
D'Antonio, L.2
Bagga, P.S.3
-
34
-
-
77953192496
-
A non-empirical chromophoric interpretation of CD spectra of DNA Gquadruplex structures
-
Masiero, S., Trotta, R., Pieraccini, S., De Tito, S., Perone, R., Randazzo, A. and Spada, G.P. (2010) A non-empirical chromophoric interpretation of CD spectra of DNA Gquadruplex structures. Org. Biomol. Chem., 8, 2683-2692.
-
(2010)
Org. Biomol. Chem.
, vol.8
, pp. 2683-2692
-
-
Masiero, S.1
Trotta, R.2
Pieraccini, S.3
De Tito, S.4
Perone, R.5
Randazzo, A.6
Spada, G.P.7
-
35
-
-
80155214231
-
Topological characterization of nucleic acid G-quadruplexes by UV absorption and circular dichroism
-
Karsisiotis, A.I., Hessari, N.M., Novellino, E., Spada, G.P., Randazzo, A. and Webba da Silva, M. (2011) Topological characterization of nucleic acid G-quadruplexes by UV absorption and circular dichroism. Angew. Chem. Int. Ed. Engl., 50, 10645-10648.
-
(2011)
Angew. Chem. Int. Ed. Engl.
, vol.50
, pp. 10645-10648
-
-
Karsisiotis, A.I.1
Hessari, N.M.2
Novellino, E.3
Spada, G.P.4
Randazzo, A.5
Webba Da Silva, M.6
-
36
-
-
84875896821
-
Circular dichroism of quadruplex structures
-
Randazzo, A., Spada, G.P. and da Silva, M.W. (2013) Circular dichroism of quadruplex structures. Top. Curr. Chem., 330, 67-86.
-
(2013)
Top. Curr. Chem.
, vol.330
, pp. 67-86
-
-
Randazzo, A.1
Spada, G.P.2
Da Silva, M.W.3
-
37
-
-
84860166246
-
State-of-The-Art methodologies for the discovery and characterization of DNA G-quadruplex binders
-
Pagano, B., Cosconati, S., Gabelica, V., Petraccone, L., De Tito, S., Marinelli, L., La Pietra, V., di Leva, F.S., Lauri, I., Trotta, R. et al. (2012) State-of-The-Art methodologies for the discovery and characterization of DNA G-quadruplex binders. Curr. Pharm. Des., 18, 1880-1899.
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 1880-1899
-
-
Pagano, B.1
Cosconati, S.2
Gabelica, V.3
Petraccone, L.4
De Tito, S.5
Marinelli, L.6
La Pietra, V.7
Di Leva, F.S.8
Lauri, I.9
Trotta, R.10
-
38
-
-
6944239985
-
Biological activity of the G-quadruplex ligand RHPS4 (3, 11-difluoro-6 8 13-Trimethyl-8H-quino[4 3 2-kl]acridinium methosulfate) is associated with telomere capping alteration
-
Leonetti, C., Amodei, S., D'Angelo, C., Rizzo, A., Benassi, B., Antonelli, A., Elli, R., Stevens, M.F., D'Incalci, M., Zupi, G. et al. (2004) Biological activity of the G-quadruplex ligand RHPS4 (3, 11-difluoro-6, 8, 13-Trimethyl-8H-quino[4, 3, 2-kl]acridinium methosulfate) is associated with telomere capping alteration. Mol. Pharmacol., 66, 1138-1146.
-
(2004)
Mol Pharmacol
, vol.66
, pp. 1138-1146
-
-
Leonetti, C.1
Amodei, S.2
D'Angelo, C.3
Rizzo, A.4
Benassi, B.5
Antonelli, A.6
Elli, R.7
Stevens, M.F.8
D'Incalci, M.9
Zupi, G.10
-
39
-
-
0034760505
-
Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes
-
Gowan, S.M., Heald, R., Stevens, M.F. and Kelland, L.R. (2001) Potent inhibition of telomerase by small-molecule pentacyclic acridines capable of interacting with G-quadruplexes. Mol. Pharmacol., 60, 981-988.
-
(2001)
Mol. Pharmacol.
, vol.60
, pp. 981-988
-
-
Gowan, S.M.1
Heald, R.2
Stevens, M.F.3
Kelland, L.R.4
-
40
-
-
34147171490
-
Endothelial cell migration during angiogenesis
-
Lamalice, L., Le Boeuf, F. and Huot, J. (2007) Endothelial cell migration during angiogenesis. Circ. Res., 100, 782-794.
-
(2007)
Circ. Res.
, vol.100
, pp. 782-794
-
-
Lamalice, L.1
Le Boeuf, F.2
Huot, J.3
-
41
-
-
79952260703
-
N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage
-
Casagrande, V., Salvati, E., Alvino, A., Bianco, A., Ciammaichella, A., D'Angelo, C., Ginnari-Satriani, L., Serrilli, A.M., Iachettini, S., Leonetti, C. et al. (2011) N-cyclic bay-substituted perylene G-quadruplex ligands have selective antiproliferative effects on cancer cells and induce telomere damage. J. Med. Chem., 54, 1140-1156.
-
(2011)
J. Med. Chem.
, vol.54
, pp. 1140-1156
-
-
Casagrande, V.1
Salvati, E.2
Alvino, A.3
Bianco, A.4
Ciammaichella, A.5
D'Angelo, C.6
Ginnari-Satriani, L.7
Serrilli, A.M.8
Iachettini, S.9
Leonetti, C.10
-
42
-
-
84870275680
-
Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: Increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells
-
Franceschin, M., Rizzo, A., Casagrande, V., Salvati, E., Alvino, A., Altieri, A., Ciammaichella, A., Iachettini, S., Leonetti, C., Ortaggi, G. et al. (2012) Aromatic core extension in the series of N-cyclic bay-substituted perylene G-quadruplex ligands: Increased telomere damage, antitumor activity, and strong selectivity for neoplastic over healthy cells. ChemMedChem, 7, 2144-2154.
-
(2012)
ChemMedChem
, vol.7
, pp. 2144-2154
-
-
Franceschin, M.1
Rizzo, A.2
Casagrande, V.3
Salvati, E.4
Alvino, A.5
Altieri, A.6
Ciammaichella, A.7
Iachettini, S.8
Leonetti, C.9
Ortaggi, G.10
-
43
-
-
74149095063
-
Driving Rho GTPase activity in endothelial cells regulates barrier integrity
-
Beckers, C.M., van Hinsbergh, V.W. and van Nieuw Amerongen, G.P. (2010) Driving Rho GTPase activity in endothelial cells regulates barrier integrity. Thromb Haemost, 103, 40-55.
-
(2010)
Thromb Haemost
, vol.103
, pp. 40-55
-
-
Beckers, C.M.1
Van Hinsbergh, V.W.2
Van Nieuw Amerongen, G.P.3
-
44
-
-
0036325594
-
Rac regulates endothelial morphogenesis and capillary assembly
-
Connolly, J.O., Simpson, N., Hewlett, L. and Hall, A. (2002) Rac regulates endothelial morphogenesis and capillary assembly. Mol. Biol. Cell, 13, 2474-2485.
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 2474-2485
-
-
Connolly, J.O.1
Simpson, N.2
Hewlett, L.3
Hall, A.4
-
45
-
-
27244435211
-
Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents
-
DOI 10.1093/nar/gki917
-
Sun, D., Guo, K., Rusche, J.J. and Hurley, L.H. (2005) Facilitation of a structural transition in the polypurine/polypyrimidine tract within the proximal promoter region of the human VEGF gene by the presence of potassium and G-quadruplex-interactive agents. Nucleic Acids Res., 33, 6070-6080. (Pubitemid 41742625
-
(2005)
Nucleic Acids Research
, vol.33
, Issue.18
, pp. 6070-6080
-
-
Sun, D.1
Guo, K.2
Rusche, J.J.3
Hurley, L.H.4
-
46
-
-
79952344184
-
Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene
-
Sun, D., Guo, K. and Shin, Y.J. (2011) Evidence of the formation of G-quadruplex structures in the promoter region of the human vascular endothelial growth factor gene. Nucleic Acids Res., 39, 1256-1265.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 1256-1265
-
-
Sun, D.1
Guo, K.2
Shin, Y.J.3
-
47
-
-
84655169275
-
Down-regulation of the human VEGF gene expression by perylene monoimide derivatives
-
Taka, T., Joonlasak, K., Huang, L., Randall Lee, T., Chang, S.W. and Tuntiwechapikul, W. (2012) Down-regulation of the human VEGF gene expression by perylene monoimide derivatives. Bioorg. Med. Chem. Lett., 22, 518-522.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 518-522
-
-
Taka, T.1
Joonlasak, K.2
Huang, L.3
Randall Lee, T.4
Chang, S.W.5
Tuntiwechapikul, W.6
-
48
-
-
28944442742
-
Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1 promoter
-
DOI 10.1021/bi051618u
-
De Armond, R., Wood, S., Sun, D., Hurley, L.H. and Ebbinghaus, S.W. (2005) Evidence for the presence of a guanine quadruplex forming region within a polypurine tract of the hypoxia inducible factor 1alpha promoter. Biochemistry, 44, 16341-16350. (Pubitemid 41785833
-
(2005)
Biochemistry
, vol.44
, Issue.49
, pp. 16341-16350
-
-
De Armond, R.1
Wood, S.2
Sun, D.3
Hurley, L.H.4
Ebbinghaus, S.W.5
-
49
-
-
84865527719
-
A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines
-
Lombardo, C.M., Welsh, S.J., Strauss, S.J., Dale, A.G., Todd, A.K., Nanjunda, R., Wilson, W.D. and Neidle, S. (2012) A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines. Bioorg. Med. Chem. Lett., 22, 5984-5988.
-
(2012)
Bioorg. Med. Chem. Lett.
, vol.22
, pp. 5984-5988
-
-
Lombardo, C.M.1
Welsh, S.J.2
Strauss, S.J.3
Dale, A.G.4
Todd, A.K.5
Nanjunda, R.6
Wilson, W.D.7
Neidle, S.8
-
50
-
-
38049017592
-
Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4
-
Qin, Y., Rezler, E.M., Gokhale, V., Sun, D. and Hurley, L.H. (2007) Characterization of the G-quadruplexes in the duplex nuclease hypersensitive element of the PDGF-A promoter and modulation of PDGF-A promoter activity by TMPyP4. Nucleic Acids Res., 35, 7698-7713.
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7698-7713
-
-
Qin, Y.1
Rezler, E.M.2
Gokhale, V.3
Sun, D.4
Hurley, L.H.5
-
51
-
-
58149151351
-
Platination of telomeric sequences and nuclease hypersensitive elements of human c-myc and PDGF-A promoters and their ability to form G-quadruplexes
-
Viglasky, V. (2009) Platination of telomeric sequences and nuclease hypersensitive elements of human c-myc and PDGF-A promoters and their ability to form G-quadruplexes. FEBS J., 276, 401-409.
-
(2009)
FEBS J.
, vol.276
, pp. 401-409
-
-
Viglasky, V.1
-
52
-
-
77952328975
-
Molecular cloning of the human plateletderived growth factor receptor beta (PDGFR-beta promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression
-
Qin, Y., Fortin, J.S., Tye, D., Gleason-Guzman, M., Brooks, T.A. and Hurley, L.H. (2010) Molecular cloning of the human plateletderived growth factor receptor beta (PDGFR-beta) promoter and drug targeting of the G-quadruplex-forming region to repress PDGFR-beta expression. Biochemistry, 49, 4208-4219.
-
(2010)
Biochemistry
, vol.49
, pp. 4208-4219
-
-
Qin, Y.1
Fortin, J.S.2
Tye, D.3
Gleason-Guzman, M.4
Brooks, T.A.5
Hurley, L.H.6
-
53
-
-
84865117406
-
The major G-quadruplex formed in the human platelet-derived growth factor receptor beta promoter adopts a novel broken-strand structure in K+solution
-
Chen, Y., Agrawal, P., Brown, R.V., Hatzakis, E., Hurley, L. and Yang, D. (2012) The major G-quadruplex formed in the human platelet-derived growth factor receptor beta promoter adopts a novel broken-strand structure in K+solution. J. Am. Chem. Soc., 134, 13220-13223.
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13220-13223
-
-
Chen, Y.1
Agrawal, P.2
Brown, R.V.3
Hatzakis, E.4
Hurley, L.5
Yang, D.6
-
54
-
-
0029147486
-
Cloning and functional analysis of the promoter for KDR/flk-1 a receptor for vascular endothelial growth factor
-
Patterson, C., Perrella, M.A., Hsieh, C.M., Yoshizumi, M., Lee, M.E. and Haber, E. (1995) Cloning and functional analysis of the promoter for KDR/flk-1, a receptor for vascular endothelial growth factor. J. Biol. Chem., 270, 23111-23118.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 23111-23118
-
-
Patterson, C.1
Perrella, M.A.2
Hsieh, C.M.3
Yoshizumi, M.4
Lee, M.E.5
Haber, E.6
-
55
-
-
77449111348
-
Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay
-
Sun, D. and Hurley, L.H. (2010) Biochemical techniques for the characterization of G-quadruplex structures: EMSA, DMS footprinting, and DNA polymerase stop assay. Methods Mol. Biol., 608, 65-79.
-
(2010)
Methods Mol. Biol.
, vol.608
, pp. 65-79
-
-
Sun, D.1
Hurley, L.H.2
|