Anti-inflammatory and antiviral effects of indirubin derivatives in influenza A (H5N1) virus infected primary human peripheral blood-derived macrophages and alveolar epithelial cells

Antiviral Research

Volumn 106, Issue 1, 2014, Pages 95-104

  Mok, Chris K P ^a,b   Kang, Sara S R ^a   Chan, Renee W Y ^a   Yue, Patrick Y K ^c   Mak, Nai K ^c   Poon, Leo L M ^a   Wong, Ricky N S ^c   Peiris, J S Malik ^a,b   Chan, Michael C W ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HKU PASTEUR RESEARCH CENTRE   (Hong Kong)

^c HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Indirubin; Influenza; IP 10; Macrophages; Pneumocytes

Indexed keywords

ALPHA INTERFERON; ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; E 804; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INDIRUBIN 3' OXIME; INTERLEUKIN 1BETA; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; OXIME DERIVATIVE; RANTES; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; INDIRUBIN; INDOLE DERIVATIVE; INDIRUBIN DERIVATIVE;

ANTIINFLAMMATORY ACTIVITY; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; GENE DOSAGE; HUMAN; HUMAN CELL; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; LUNG ALVEOLUS CELL; MACROPHAGE; MTT ASSAY; PRIMARY CELL CULTURE; PRIORITY JOURNAL; SEASONAL INFLUENZA; SUPERNATANT; VIRUS GENE; VIRUS INFECTIVITY; VIRUS REPLICATION; VIRUS TITRATION; VIRUS TRANSCRIPTION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL CULTURE; DRUG EFFECTS; EPITHELIUM CELL; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; VIROLOGY; ANIMAL CELL; CYTOKINE PRODUCTION; DRUG EFFECT; LUNG ALVEOLUS EPITHELIUM; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PNEUMONIA; VIRUS STRAIN;

ANTI-INFLAMMATORY AGENTS; ANTIVIRAL AGENTS; CELLS, CULTURED; CYTOKINES; EPITHELIAL CELLS; HUMANS; INDOLES; INFLUENZA A VIRUS, H5N1 SUBTYPE; MACROPHAGES; VIRUS REPLICATION;

EID: 84898939549     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2014.03.019     Document Type: Article

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