ATP6V0C knockdown in neuroblastoma cells alters autophagy-lysosome pathway function and metabolism of proteins that accumulate in neurodegenerative disease

PLoS ONE

Volumn 9, Issue 4, 2014, Pages

  Mangieri, Leandra R ^a   Mader, Burton J ^a,c   Thomas, Cailin E ^a   Taylor, Charles A ^a   Luker, Austin M ^a   Tse, Tonia E ^a   Huisingh, Carrie ^b   Shacka, John J ^a,b  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; BAFILOMYCIN A1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3 II; PROPIDIUM IODIDE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; APP PROTEIN, HUMAN; ATP6V0C PROTEIN, HUMAN; LAMP1 PROTEIN, HUMAN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MAP1LC3A PROTEIN, HUMAN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE;

ARTICLE; AUTOLYSOSOME; CANCER CELL; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL DIFFERENTIATION; CELL FUNCTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEGENERATIVE DISEASE; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; NEUROBLASTOMA; PATHOGENESIS; PHENOTYPE; PROTEIN LOCALIZATION; PROTEIN METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; AUTOPHAGY; LYSOSOME; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ALPHA-SYNUCLEIN; AMYLOID BETA-PROTEIN PRECURSOR; AUTOPHAGY; CELL LINE, TUMOR; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MICROTUBULE-ASSOCIATED PROTEINS; NEUROBLASTOMA; NEURODEGENERATIVE DISEASES; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 84898871064     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0093257     Document Type: Article

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