Glucocerebrosidase Mutations alter the endoplasmic reticulum and lysosomes in Lewy body disease

Journal of Neurochemistry

Volumn 123, Issue 2, 2012, Pages 298-309

  Kurzawa Akanbi, Marzena ^a   Hanson, Peter S ^a   Blain, Peter G ^a   Lett, Debra J ^a   McKeith, Ian G ^a   Chinnery, Patrick F ^a   Morris, Christopher M ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

dementia with Lewy bodies; endoplasmic reticulum; glucocerebrosidase; Lewy body disease; lysosome; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; CATHEPSIN D; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 94; GLUCOSYLCERAMIDASE; ISOENZYME; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2;

ADULT; AGED; ARTICLE; BIOACCUMULATION; CADAVER; CELL DAMAGE; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REPRESSION; FEMALE; GBA GENE; GENE; GENE MUTATION; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYSOSOME; MAJOR CLINICAL STUDY; MALE; NERVE CELL CULTURE; NEURAL STEM CELL; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; UNFOLDED PROTEIN RESPONSE;

AGED; CASE-CONTROL STUDIES; CELLS, CULTURED; COHORT STUDIES; ENDOPLASMIC RETICULUM; FEMALE; GLUCOSYLCERAMIDASE; HUMANS; LEWY BODY DISEASE; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MALE; MIDDLE AGED; MUTATION;

EID: 84867090941     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07879.x     Document Type: Article

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