메뉴 건너뛰기




Volumn 11, Issue 4, 2014, Pages 4049-4065

Relationship between obesity, adipocytokines and inflammatory markers in type 2 diabetes: Relevance for cardiovascular risk prevention

Author keywords

Adipocytokines; Cardiovascular prevention; Diabetes; Inflammatory markers; Obesity

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; C REACTIVE PROTEIN; INTERLEUKIN 6; LEPTIN; RESISTIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84898858718     PISSN: 16617827     EISSN: 16604601     Source Type: Journal    
DOI: 10.3390/ijerph110404049     Document Type: Article
Times cited : (59)

References (65)
  • 1
    • 57249103368 scopus 로고    scopus 로고
    • Risk of cardiovascular disease and mortality in overweight and obese patients with type 2 diabetes: An observational study in 13, 087 patients
    • Eeg-Olofsson, K.; Cederholm, J.; Nilsson, P. M.; Zethelius, B.; Nunez, L.; Gudbjörnsdóttir, S.; Eliasson, B. Risk of cardiovascular disease and mortality in overweight and obese patients with type 2 diabetes: An observational study in 13, 087 patients. Diabetologia 2009, 52, 65-73.
    • (2009) Diabetologia , vol.52 , pp. 65-73
    • Eeg-Olofsson, K.1    Cederholm, J.2    Nilsson, P.M.3    Zethelius, B.4    Nunez, L.5    Gudbjörnsdóttir, S.6    Eliasson, B.7
  • 2
    • 84879379552 scopus 로고    scopus 로고
    • Predicting changes in cardiovascular risk factors in type 2 diabetes in the post-UKPDS era: Longitudinal analysis of the Swedish national diabetes register
    • doi: 10. 1155/2013/241347
    • Kiadaliri, A.; Clarke, P. M.; Gerdtham, U. G.; Nilsson, P.; Eliasson, B.; Gudbjörnsdottir, S.; Steen, K. A. Predicting changes in cardiovascular risk factors in type 2 diabetes in the post-UKPDS era: Longitudinal analysis of the Swedish national diabetes register. Diabetes Res. 2013, 2013, doi: 10. 1155/2013/241347.
    • (2013) Diabetes Res , vol.2013
    • Kiadaliri, A.1    Clarke, P.M.2    Gerdtham, U.G.3    Nilsson, P.4    Eliasson, B.5    Gudbjörnsdottir, S.6    Steen, K.A.7
  • 3
    • 84863981484 scopus 로고    scopus 로고
    • A randomised trial of a weight loss intervention for overweight and obese people diagnosed with coronary heart disease and/or type 2 diabetes
    • Gallagher, R.; Kirkness, A.; Zelestis, E.; Hollams, D.; Kneale, C.; Armari, E.; Bennett, T.; Daly, J.; Tofler, G. A randomised trial of a weight loss intervention for overweight and obese people diagnosed with coronary heart disease and/or type 2 diabetes. Ann. Behav. Med. 2012, 44, 119-128.
    • (2012) Ann. Behav. Med , vol.44 , pp. 119-128
    • Gallagher, R.1    Kirkness, A.2    Zelestis, E.3    Hollams, D.4    Kneale, C.5    Armari, E.6    Bennett, T.7    Daly, J.8    Tofler, G.9
  • 4
    • 84879128758 scopus 로고    scopus 로고
    • Intensive weight loss intervention in older individuals: Results from the action for health in diabetes type 2 diabetes mellitus trial
    • Action for Health in Diabetes Research Group
    • Espeland, M. A.; Rejeski, W. J.; West, D. S.; Action for Health in Diabetes Research Group. Intensive weight loss intervention in older individuals: Results from the action for health in diabetes type 2 diabetes mellitus trial. J. Amer. Geriat. Soc. 2013, 61, 912-922.
    • (2013) J. Amer. Geriat. Soc , vol.61 , pp. 912-922
    • Espeland, M.A.1    Rejeski, W.J.2    West, D.S.3
  • 5
    • 85027917623 scopus 로고    scopus 로고
    • Effect of aerobic interval training on exercise capacity and metabolic risk factors in people with cardiometabolic disorders: A meta-analysis
    • Hwang, C. L.; Wu, Y. T.; Chou, C. H. Effect of aerobic interval training on exercise capacity and metabolic risk factors in people with cardiometabolic disorders: A meta-analysis. J. Cardiopulm. Rehabil. Prev. 2011, 31, 378-385.
    • (2011) J. Cardiopulm. Rehabil. Prev , vol.31 , pp. 378-385
    • Hwang, C.L.1    Wu, Y.T.2    Chou, C.H.3
  • 6
    • 77953509678 scopus 로고    scopus 로고
    • Adipose tissue, inflammation and atherosclerosis
    • Gustafson, B. Adipose tissue, inflammation and atherosclerosis. J. Atheroscler. Thromb. 2010, 17, 332-341.
    • (2010) J. Atheroscler. Thromb , vol.17 , pp. 332-341
    • Gustafson, B.1
  • 7
    • 84863455384 scopus 로고    scopus 로고
    • Inflammation and type 2 diabetes
    • Calle, M. C.; Fernandez, M. L. Inflammation and type 2 diabetes. Diabetes Metab. 2012, 38, 183-191.
    • (2012) Diabetes Metab , vol.38 , pp. 183-191
    • Calle, M.C.1    Fernandez, M.L.2
  • 10
  • 14
    • 74249096153 scopus 로고    scopus 로고
    • Adiponectin directly improves endothelial dysfunction in obese rats through the AMPK-eNOS Pathway
    • Deng, G.; Long, Y.; Yu, Y. R.; Li, M. R. Adiponectin directly improves endothelial dysfunction in obese rats through the AMPK-eNOS Pathway. Int. J. Obesity 2010, 34, 165-171.
    • (2010) Int. J. Obesity , vol.34 , pp. 165-171
    • Deng, G.1    Long, Y.2    Yu, Y.R.3    Li, M.R.4
  • 15
    • 34247874560 scopus 로고    scopus 로고
    • Circulating leptin levels are not associated with cardiovascular morbidity and mortality in women with diabetes: A prospective cohort study
    • Brennan, A. M.; Li, T. Y.; Kelesidis, I.; Gavrila, A.; Hu, F. B.; Mantzoros, C. S. Circulating leptin levels are not associated with cardiovascular morbidity and mortality in women with diabetes: A prospective cohort study. Diabetologia 2007, 50, 1178-1185.
    • (2007) Diabetologia , vol.50 , pp. 1178-1185
    • Brennan, A.M.1    Li, T.Y.2    Kelesidis, I.3    Gavrila, A.4    Hu, F.B.5    Mantzoros, C.S.6
  • 16
    • 58049219012 scopus 로고    scopus 로고
    • Adipose tissue dysfunction in obesity, diabetes, and vascular diseases
    • Hajer, G. R.; van Haeften, T. W.; Visseren, F. L. J. Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. Eur. Heart J. 2008, 29, 2959-2971.
    • (2008) Eur. Heart J , vol.29 , pp. 2959-2971
    • Hajer, G.R.1    van Haeften, T.W.2    Visseren, F.L.J.3
  • 17
    • 34547485312 scopus 로고    scopus 로고
    • The endothelium and vascular inflammation in diabetes
    • Hartge, M. M.; Unger, T.; Kontscher, U. The endothelium and vascular inflammation in diabetes. Diab. Vasc. Res. 2007, 4, 84-88.
    • (2007) Diab. Vasc. Res , vol.4 , pp. 84-88
    • Hartge, M.M.1    Unger, T.2    Kontscher, U.3
  • 18
    • 56749103005 scopus 로고    scopus 로고
    • Associations of resistin with inflammatory and fibrinolytic markers, insulin resistance, and metabolic syndrome in middle-aged and older Chinese
    • Qi, Q.; Wang, J.; Li, H.; Yu, Z.; Ye, X.; Hu, F. B.; Franco, O. H.; Pan, A.; Liu, Y.; Lin, X. Associations of resistin with inflammatory and fibrinolytic markers, insulin resistance, and metabolic syndrome in middle-aged and older Chinese. Eur. J. Endocrinol. 2008, 159, 585-593.
    • (2008) Eur. J. Endocrinol , vol.159 , pp. 585-593
    • Qi, Q.1    Wang, J.2    Li, H.3    Yu, Z.4    Ye, X.5    Hu, F.B.6    Franco, O.H.7    Pan, A.8    Liu, Y.9    Lin, X.10
  • 19
    • 0035909997 scopus 로고    scopus 로고
    • Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS)
    • The WOSCOPS Executive Committee
    • Wallace, A. M.; McMahon, A. D.; Packard, C. J.; Kelly, A.; Shepherd, J.; Gaw, A.; Sattar, N.; The WOSCOPS Executive Committee. Plasma leptin and the risk of cardiovascular disease in the west of Scotland coronary prevention study (WOSCOPS). Circulation 2001, 104, 3052-3056.
    • (2001) Circulation , vol.104 , pp. 3052-3056
    • Wallace, A.M.1    McMahon, A.D.2    Packard, C.J.3    Kelly, A.4    Shepherd, J.5    Gaw, A.6    Sattar, N.7
  • 21
    • 2342453229 scopus 로고    scopus 로고
    • High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians
    • Vozarova de Courten, B.; Degawa-Yamauchi, M.; Considine, R. V.; Tataranni, P. A. High serum resistin is associated with an increase in adiposity but not a worsening of insulin resistance in Pima Indians. Diabetes 2004, 53, 1279-1284.
    • (2004) Diabetes , vol.53 , pp. 1279-1284
    • Vozarova de Courten, B.1    Degawa-Yamauchi, M.2    Considine, R.V.3    Tataranni, P.A.4
  • 22
    • 1242313298 scopus 로고    scopus 로고
    • Correlation between serum resistin level and adiposity in obese individuals
    • Azuma, K.; Katsukawa, F.; Oguchi, S.; et al. Correlation between serum resistin level and adiposity in obese individuals. Obesity 2003, 11, 997-1001.
    • (2003) Obesity , vol.11 , pp. 997-1001
    • Azuma, K.1    Katsukawa, F.2    Oguchi, S.3
  • 23
    • 10744220840 scopus 로고    scopus 로고
    • Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus
    • Youn, B. S.; YU, K. Y.; Park, H. J.; Roberts, C. K.; Manson, J. A. E.; Rifai, N.; Buring, J. E.; Gaziano, J. M.; Liu, S. Plasma resistin concentrations measured by enzyme-linked immunosorbent assay using a newly developed monoclonal antibody are elevated in individuals with type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 2004, 89, 150-156.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 150-156
    • Youn, B.S.1    Yu, K.Y.2    Park, H.J.3    Roberts, C.K.4    Manson, J.A.E.5    Rifai, N.6    Buring, J.E.7    Gaziano, J.M.8    Liu, S.9
  • 24
    • 9144244927 scopus 로고    scopus 로고
    • Resistin and type 2 diabetes: Regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes
    • McTernan, P. G.; Fisher, F. M.; Valsamakis, G.; Chetty, R.; Harte, A.; MCternan, C. L.; Clark, P. M. S.; Smith, S. A.; Barnett, A. H.; Kumars, S. Resistin and type 2 diabetes: Regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes. J. Clin. Endocrinol. Metab. 2003, 88, 6098-6106.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 6098-6106
    • McTernan, P.G.1    Fisher, F.M.2    Valsamakis, G.3    Chetty, R.4    Harte, A.5    McTernan, C.L.6    Clark, P.M.S.7    Smith, S.A.8    Barnett, A.H.9    Kumars, S.10
  • 25
    • 1942504927 scopus 로고    scopus 로고
    • Relationship between serum resistin concentrations and insulin resistance in nonobese, obese, and obese diabetic subjects
    • Heilbronn, L. K.; Rood, J.; Janderova, L.; Albu, J. B.; Kelley, D. E.; Ravussin, E.; Smith, S. R. Relationship between serum resistin concentrations and insulin resistance in nonobese, obese, and obese diabetic subjects. J. Clin. Endocrinol. Metab. 2004, 89, 1844-1848.
    • (2004) J. Clin. Endocrinol. Metab , vol.89 , pp. 1844-1848
    • Heilbronn, L.K.1    Rood, J.2    Janderova, L.3    Albu, J.B.4    Kelley, D.E.5    Ravussin, E.6    Smith, S.R.7
  • 27
    • 59649104145 scopus 로고    scopus 로고
    • The evolving role of C-reactive protein in atherothrombosis
    • Devaraj, S.; Singh, U.; Jialal, I. The evolving role of C-reactive protein in atherothrombosis. Clin. Chem. 2009, 55, 229-238.
    • (2009) Clin. Chem , vol.55 , pp. 229-238
    • Devaraj, S.1    Singh, U.2    Jialal, I.3
  • 30
    • 34047155003 scopus 로고    scopus 로고
    • Visceral fat adipokine secretion is associated with systemic inflammation in obese humans
    • Fontana, L.; Eagon, J. C.; Trujillo, M. E.; Scherer, P. E.; Klein, S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes 2007, 56, 1010-1013.
    • (2007) Diabetes , vol.56 , pp. 1010-1013
    • Fontana, L.1    Eagon, J.C.2    Trujillo, M.E.3    Scherer, P.E.4    Klein, S.5
  • 32
  • 33
    • 0037133285 scopus 로고    scopus 로고
    • Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year
    • Ziccardi, P.; Nappo, F.; Giugliano, G.; Esposito, K.; Marfella, R.; Cioffi, M.; D'Andrea, F.; Molinari, A. M.; Giugliano, D. Reduction of inflammatory cytokine concentrations and improvement of endothelial functions in obese women after weight loss over one year. Circulation 2002, 105, 804-809.
    • (2002) Circulation , vol.105 , pp. 804-809
    • Ziccardi, P.1    Nappo, F.2    Giugliano, G.3    Esposito, K.4    Marfella, R.5    Cioffi, M.6    D'Andrea, F.7    Molinari, A.M.8    Giugliano, D.9
  • 34
    • 41649093318 scopus 로고    scopus 로고
    • Inflammatory mechanisms in the regulation of insulin resistance
    • Tilg, H.; Moschen, A. R. Inflammatory mechanisms in the regulation of insulin resistance. Mol. Med. 2008, 14, 222-231.
    • (2008) Mol. Med , vol.14 , pp. 222-231
    • Tilg, H.1    Moschen, A.R.2
  • 35
    • 44949249095 scopus 로고    scopus 로고
    • Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome
    • Skalicky, J.; Muzakova, V.; Kandar, R.; Meloun, M.; Rousar, T.; Palicka, V. Evaluation of oxidative stress and inflammation in obese adults with metabolic syndrome. Clin. Chem. Lab. Med. 2008, 46, 499-505.
    • (2008) Clin. Chem. Lab. Med , vol.46 , pp. 499-505
    • Skalicky, J.1    Muzakova, V.2    Kandar, R.3    Meloun, M.4    Rousar, T.5    Palicka, V.6
  • 36
    • 84858023413 scopus 로고    scopus 로고
    • Circulating levels od TNF are associated with impaired glucose tolerance, icreased insulin reistance, and ethinicity: The insulin resistance atherosclerosis study
    • Olson, C. N.; Callas, W. P.; Hanley, A. J. G.; Festa, A.; Haffner, S. M.; Wagenknecht, L. E.; Tracy, R. P. Circulating levels od TNF are associated with impaired glucose tolerance, icreased insulin reistance, and ethinicity: The insulin resistance atherosclerosis study. J. Clin. Endocrinol. Metab. 2012, 97, 1032-1040.
    • (2012) J. Clin. Endocrinol. Metab , vol.97 , pp. 1032-1040
    • Olson, C.N.1    Callas, W.P.2    Hanley, A.J.G.3    Festa, A.4    Haffner, S.M.5    Wagenknecht, L.E.6    Tracy, R.P.7
  • 37
    • 34250628015 scopus 로고    scopus 로고
    • The correlation between adiposity and adiponectin, tumor necrosis factor alpha, interleukin-6 and high-sensitivity C-reactive protein levels. Is adipocyte size associated with the inflammation in adults?
    • Bahceci, M.; Gokalp, D.; Bahceci, S.; Tuzcu, A.; Atmaca, S.; Arikan, S. The correlation between adiposity and adiponectin, tumor necrosis factor alpha, interleukin-6 and high-sensitivity C-reactive protein levels. Is adipocyte size associated with the inflammation in adults? J. Endocrinol. Invest. 2007, 30, 210-214.
    • (2007) J. Endocrinol. Invest , vol.30 , pp. 210-214
    • Bahceci, M.1    Gokalp, D.2    Bahceci, S.3    Tuzcu, A.4    Atmaca, S.5    Arikan, S.6
  • 40
    • 84898908157 scopus 로고    scopus 로고
    • Group for Diabetes
    • National Committee for the Clinical Guidelines for Good Clinical Practice, Agencija za Akreditaciju Zdravstvenih Ustanova Srbije: Beograd, Serbia
    • National Committee for the Clinical Guidelines for Good Clinical Practice. Group for Diabetes. Nacionalni Vodič Dobre Kliničke Prakse Diabetes Mellitus; Agencija za Akreditaciju Zdravstvenih Ustanova Srbije: Beograd, Serbia, 2012.
    • (2012) Nacionalni Vodič Dobre Kliničke Prakse Diabetes Mellitus
  • 41
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews, D. R.; Hosker, J. P.; Rudenski, A. S. Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 13, 412-419.
    • (1985) Diabetologia , vol.13 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 42
    • 84895900605 scopus 로고    scopus 로고
    • Low-molecular-weight adiponectin and high-molecular-weight adiponectinlevels in relation to diabetes
    • Saku Cohort Study Group, doi: 10. 1002/oby. 20553
    • Goto, M.; Goto, A.; Morita, A; Deura, K.; Sasaki, S.; Aiba, N.; Shimbo, T.; Terauchi, Y.; Miyachi, M.; Noda, M.; Watanabe, S.; Saku Cohort Study Group. Low-molecular-weight adiponectin and high-molecular-weight adiponectinlevels in relation to diabetes. Obesity 2013, 1, doi: 10. 1002/oby. 20553.
    • (2013) Obesity , vol.1
    • Goto, M.1    Goto, A.2    Morita, A.3    Deura, K.4    Sasaki, S.5    Aiba, N.6    Shimbo, T.7    Terauchi, Y.8    Miyachi, M.9    Noda, M.10    Watanabe, S.11
  • 43
    • 21144438388 scopus 로고    scopus 로고
    • Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin resistance and adiposity
    • Hasegawa, G.; Ohta, M.; Ichida, Y.; Obayashi, H.; Shigeta, M.; Yamasaki, M.; Fukui, M.; Yoshikawa, T.; Nakamura, N. Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin resistance and adiposity. Acta Diabetol. 2005, 42, 104-109.
    • (2005) Acta Diabetol , vol.42 , pp. 104-109
    • Hasegawa, G.1    Ohta, M.2    Ichida, Y.3    Obayashi, H.4    Shigeta, M.5    Yamasaki, M.6    Fukui, M.7    Yoshikawa, T.8    Nakamura, N.9
  • 44
    • 77954865132 scopus 로고    scopus 로고
    • Plasma adipokine and inflammatory marker concentrations are altered in obese, as opposed to non-obese, type 2 diabetes patients
    • Hansen, D.; Dendale, P.; Beelen, M.; Jonkers, R. A.; Mullens, A.; Corluy, L.; Meeusen, R.; van Loon, L. J. Plasma adipokine and inflammatory marker concentrations are altered in obese, as opposed to non-obese, type 2 diabetes patients. Eur. J. Appl. Physiol. 2010, 109, 397-404.
    • (2010) Eur. J. Appl. Physiol , vol.109 , pp. 397-404
    • Hansen, D.1    Dendale, P.2    Beelen, M.3    Jonkers, R.A.4    Mullens, A.5    Corluy, L.6    Meeusen, R.7    van Loon, L.J.8
  • 45
    • 22744443610 scopus 로고    scopus 로고
    • Type 2 diabetes in non-obese Indian subjects is associated with reduced leptin levels: Study from Mumbai, western India
    • Marita, A. R.; Sarkar, J. A.; Rane, S. Type 2 diabetes in non-obese Indian subjects is associated with reduced leptin levels: Study from Mumbai, western India. Mol. Cell. Biochem. 2005, 275, 143-151.
    • (2005) Mol. Cell. Biochem , vol.275 , pp. 143-151
    • Marita, A.R.1    Sarkar, J.A.2    Rane, S.3
  • 46
    • 33644631393 scopus 로고    scopus 로고
    • Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs. obese type 2 diabetes
    • Yang, Y.; Lu, H. L.; Zhang, J.; Yu, H. Y.; Wang, H. W.; Zhang, M. X.; Cianflone, K. Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs. obese type 2 diabetes. Int. J. Obesity 2006, 30, 439-446.
    • (2006) Int. J. Obesity , vol.30 , pp. 439-446
    • Yang, Y.1    Lu, H.L.2    Zhang, J.3    Yu, H.Y.4    Wang, H.W.5    Zhang, M.X.6    Cianflone, K.7
  • 47
    • 84875427307 scopus 로고    scopus 로고
    • Evidence of a causal relationship between adiponectin levels and insulin sensitivity: A Mendelian randomization study
    • Gao, H.; Fall, T.; van Dam, R. M.; Flyvbjerg, A.; Zethelius, B.; Ingelsson, E.; Hägg, S. Evidence of a causal relationship between adiponectin levels and insulin sensitivity: A Mendelian randomization study. Diabetes 2013, 62, 1338-1344.
    • (2013) Diabetes , vol.62 , pp. 1338-1344
    • Gao, H.1    Fall, T.2    van Dam, R.M.3    Flyvbjerg, A.4    Zethelius, B.5    Ingelsson, E.6    Hägg, S.7
  • 48
    • 84874793400 scopus 로고    scopus 로고
    • Low serum adiponectin concentrations are associated with insulin sensitivity independent of obesity in Sudanese subjects with type 2 diabetes mellitus
    • doi: 10. 1186/1758-5996-5-15
    • Abdelgadir, M.; Karlsson, A. F.; Berglund, L.; Berne, C. Low serum adiponectin concentrations are associated with insulin sensitivity independent of obesity in Sudanese subjects with type 2 diabetes mellitus. Diabetol. Metab. Synd. 2013, 5(1): 15. doi: 10. 1186/1758-5996-5-15.
    • (2013) Diabetol. Metab. Synd , vol.5 , Issue.1 , pp. 15
    • Abdelgadir, M.1    Karlsson, A.F.2    Berglund, L.3    Berne, C.4
  • 49
    • 0041853796 scopus 로고    scopus 로고
    • Leptin is reduced in lean subjects with type 2 diabetes in Bangladesh
    • doi: 10. 2337/diacare. 26. 2. 547
    • Sayeed, M. A.; Khan, A. K. A.; Mahtab, H.; Ahsan, K. A.; Banu, A.; Khanam, P. A.; Ahrén, B. Leptin is reduced in lean subjects with type 2 diabetes in Bangladesh. Diabetes Care 2003, 26 doi: 10. 2337/diacare. 26. 2. 547.
    • (2003) Diabetes Care , pp. 26
    • Sayeed, M.A.1    Khan, A.K.A.2    Mahtab, H.3    Ahsan, K.A.4    Banu, A.5    Khanam, P.A.6    Ahrén, B.7
  • 50
    • 84872775986 scopus 로고    scopus 로고
    • Serum leptin level is reduced in non-obese subjects with type 2 diabetes
    • Mohammadzadeh, G.; Zarghami, N. Serum leptin level is reduced in non-obese subjects with type 2 diabetes. Int. J. Endocrinol. Metab. 2013, 11, 3-10.
    • (2013) Int. J. Endocrinol. Metab , vol.11 , pp. 3-10
    • Mohammadzadeh, G.1    Zarghami, N.2
  • 51
    • 84874430535 scopus 로고    scopus 로고
    • Role of adipokines in cardiovascular disease
    • Mattu, H. S.; Randeva, H. S. Role of adipokines in cardiovascular disease. J. Endocrinol. 2013, 216, 17-36.
    • (2013) J. Endocrinol , vol.216 , pp. 17-36
    • Mattu, H.S.1    Randeva, H.S.2
  • 52
    • 30044447631 scopus 로고    scopus 로고
    • Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons
    • Morton, G. J.; Gelling, R. W.; Niswender, K. D.; Morrison, C. D.; Rhodes, C. J.; Schwartz, M. W. Leptin regulates insulin sensitivity via phosphatidylinositol-3-OH kinase signaling in mediobasal hypothalamic neurons. Cell. Metab. 2005, 2, 411-420.
    • (2005) Cell. Metab , vol.2 , pp. 411-420
    • Morton, G.J.1    Gelling, R.W.2    Niswender, K.D.3    Morrison, C.D.4    Rhodes, C.J.5    Schwartz, M.W.6
  • 55
    • 0242320395 scopus 로고    scopus 로고
    • Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: Cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects
    • Lee, J. H.; Chan, J. L.; Yiannakouris, N.; Kontogianni, M.; Estrada, E.; Seip, R.; Orlova, C.; Mantzoros, C. S. Circulating resistin levels are not associated with obesity or insulin resistance in humans and are not regulated by fasting or leptin administration: Cross-sectional and interventional studies in normal, insulin-resistant, and diabetic subjects. J. Clin. Endocrinol. Metab. 2003, 88, 4848-4856.
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 4848-4856
    • Lee, J.H.1    Chan, J.L.2    Yiannakouris, N.3    Kontogianni, M.4    Estrada, E.5    Seip, R.6    Orlova, C.7    Mantzoros, C.S.8
  • 56
    • 0142216501 scopus 로고    scopus 로고
    • Plasma resistin, adiponectin and leptin levels in lean and obese subjects: Correlations with insulin resistance
    • Silha, J. V.; Krsek, M.; Skrha, J. V.; Sucharda, P.; Nyomba, B. L.; Murphy, L. J. Plasma resistin, adiponectin and leptin levels in lean and obese subjects: Correlations with insulin resistance. Eur. J. Endocrinol. 2003, 149, 331-335.
    • (2003) Eur. J. Endocrinol , vol.149 , pp. 331-335
    • Silha, J.V.1    Krsek, M.2    Skrha, J.V.3    Sucharda, P.4    Nyomba, B.L.5    Murphy, L.J.6
  • 57
    • 24744468644 scopus 로고    scopus 로고
    • Serum resistin, adiposity and insulin resistance in Saudi women with type 2 diabetes mellitus
    • Al Harithy, R. N.; Al Ghamdi, S. Serum resistin, adiposity and insulin resistance in Saudi women with type 2 diabetes mellitus. Ann. Saudi Med. 2005, 25, 283-287.
    • (2005) Ann. Saudi Med , vol.25 , pp. 283-287
    • Al Harithy, R.N.1    Al Ghamdi, S.2
  • 58
    • 0031867918 scopus 로고    scopus 로고
    • Relationship between plasma tumor necrosis factor α and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus
    • Nilsson, J.; Jovinge, S.; Niemann, A.; Reneland, R.; Lithell, H. Relationship between plasma tumor necrosis factor α and insulin sensitivity in elderly men with non-insulin-dependent diabetes mellitus. Arterioscler. Thromb. Vasc. Biol. 1998, 18, 1199-1202.
    • (1998) Arterioscler. Thromb. Vasc. Biol , vol.18 , pp. 1199-1202
    • Nilsson, J.1    Jovinge, S.2    Niemann, A.3    Reneland, R.4    Lithell, H.5
  • 60
    • 0032922944 scopus 로고    scopus 로고
    • Circulating tumor necrosis factor-α concentrations in a native Canadian population with high rates of type 2 diabetes mellitus
    • Zinman, B.; Hanley, A. J. G.; Harris, S. B.; Kwan, J.; Fantus, I. G. Circulating tumor necrosis factor-α concentrations in a native Canadian population with high rates of type 2 diabetes mellitus. J. Clin. Endocrinol. Metab. 1999, 84, 272-278.
    • (1999) J. Clin. Endocrinol. Metab , vol.84 , pp. 272-278
    • Zinman, B.1    Hanley, A.J.G.2    Harris, S.B.3    Kwan, J.4    Fantus, I.G.5
  • 62
    • 0035209720 scopus 로고    scopus 로고
    • Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals
    • Van Dielen, F. M.; van't Veer, C.; Schols, A. M.; Soeters, P. B.; Buurman, W. A.; Greve, J. W. Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals. Int. J. Obes. Relat. Metab. Disord. 2001, 25, 1759-1766.
    • (2001) Int. J. Obes. Relat. Metab. Disord , vol.25 , pp. 1759-1766
    • Van Dielen, F.M.1    van't Veer, C.2    Schols, A.M.3    Soeters, P.B.4    Buurman, W.A.5    Greve, J.W.6
  • 65
    • 4644305250 scopus 로고    scopus 로고
    • Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes
    • Shetty, G. K.; Economides, P. A.; Horton, E. S.; Mantzoros, C. S.; Veves, A. Circulating adiponectin and resistin levels in relation to metabolic factors, inflammatory markers, and vascular reactivity in diabetic patients and subjects at risk for diabetes. Diabetes Care 2004, 27, 2450-2457.
    • (2004) Diabetes Care , vol.27 , pp. 2450-2457
    • Shetty, G.K.1    Economides, P.A.2    Horton, E.S.3    Mantzoros, C.S.4    Veves, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.