Circulating levels of TNF-α are associated with impaired glucose tolerance, increased insulin resistance, and ethnicity: The insulin resistance atherosclerosis study

Journal of Clinical Endocrinology and Metabolism

Volumn 97, Issue 3, 2012, Pages 1032-1040

  Olson, Nels C ^a   Callas, Peter W ^a   Hanley, Anthony J G ^b   Festa, Andreas ^c   Haffner, Steven M ^d   Wagenknecht, Lynne E ^e   Tracy, Russell P ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c ELI LILLY AND COMPANY   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH DENSITY LIPOPROTEIN; INSULIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AFRICAN AMERICAN; AGE DISTRIBUTION; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CAUCASIAN; CONTROLLED STUDY; DEMOGRAPHY; ETHNICITY; FEMALE; HISPANIC; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; INTRAVENOUS GLUCOSE TOLERANCE TEST; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; POPULATION RESEARCH; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SEX DIFFERENCE; WAIST CIRCUMFERENCE;

AFRICAN AMERICANS; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HISPANIC AMERICANS; HUMANS; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84858023413     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2011-2155     Document Type: Article

References (43)

1. Fox CS, Pencina MJ, Meigs JB, Vasan RS, Levitzky YS, D'Agostino Sr RB 2006 Trends in the incidence of type 2 diabetes mellitus from the 1970s to the 1990s: the Framingham Heart Study. Circulation 113:2914-2918 (Pubitemid 44297232)
2. Shaw JE, Sicree RA, Zimmet PZ 2010 Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87:4-14
3. Schmidt MI, Duncan BB, Sharrett AR, Lindberg G, Savage PJ, Offenbacher S, Azambuja MI, Tracy RP, Heiss G 1999 Markers of inflammation and prediction of diabetes mellitus in adults (Atherosclerosis Risk in Communities study): a cohort study. Lancet 353: 1649-1652 (Pubitemid 29224520)
4. Pradhan AD, Manson JE, Rifai N, Buring JE, Ridker PM 2001 C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 286:327-334 (Pubitemid 32656163)
5. Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, Tataranni PA 2002 High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 51:455-461 (Pubitemid 34764803)
6. Festa A, D'Agostino Jr R, Tracy RP, Haffner SM 2002 Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes 51:1131-1137 (Pubitemid 34438360)
7. Spranger J, Kroke A, Möhlig M, Hoffmann K, Bergmann MM, Ristow M, Boeing H, Pfeiffer AF 2003 Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population- based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 52:812-817 (Pubitemid 36323590)
8. Thorand B, Kolb H, Baumert J, Koenig W, Chambless L, Meisinger C, Illig T, Martin S, Herder C 2005 Elevated levels of interleukin- 18 predict the development of type 2 diabetes: results from the MONICA/KORA Augsburg Study, 1984-2002. Diabetes 54:2932-2938 (Pubitemid 41401089)
9. Bradley JR 2008 TNF-mediated inflammatory disease. J Pathol 214: 149-160 (Pubitemid 351160153)
10. Cawthorn WP, Sethi JK 2008 TNF-α and adipocyte biology. FEBS Lett 582:117-131
11. Moller DE 2000 Potential role of TNF-α in the pathogenesis of insulin resistance and type 2 diabetes. Trends Endocrinol Metab 11:212-217 (Pubitemid 30603166)
12. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM 1995 Increased adipose tissue expression of tumor necrosis factor-αin human obesity and insulin resistance. J Clin Invest 95:2409-2415
13. Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB 1995 The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 95:2111-2119
14. Van der Poll T, Romijn JA, Endert E, Borm JJ, Büller HR, Sauerwein HP 1991 Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans. Am J Physiol 261:E457-E465
15. Hivert MF, Sullivan LM, Fox CS, Nathan DM, D'Agostino Sr RB, Wilson PW, Meigs JB 2008 Associations of adiponectin, resistin, and tumor necrosis factor-α with insulin resistance. J Clin Endocrinol Metab 93:3165-3172
16. Plomgaard P, Nielsen AR, Fischer CP, Mortensen OH, Broholm C, Penkowa M, Krogh-Madsen R, Erikstrup C, Lindegaard B, Petersen AM, Taudorf S, Pedersen BK 2007 Associations between insulin resistance and TNF-α in plasma, skeletal muscle and adipose tissue in humans with and without type 2 diabetes. Diabetologia 50:2562-2571 (Pubitemid 350060651)
17. de Rekeneire N, Peila R, Ding J, Colbert LH, Visser M, Shorr RI, Kritchevsky SB, Kuller LH, Strotmeyer ES, Schwartz AV, Vellas B, Harris TB 2006 Diabetes, hyperglycemia, and inflammation in older individuals: the health, aging and body composition study. Diabetes Care 29:1902-1908 (Pubitemid 44156650)
18. Zinman B, Hanley AJ, Harris SB, Kwan J, Fantus IG 1999 Circulating tumor necrosis factor-α concentrations in a native Canadian population with high rates of type 2 diabetes mellitus. J Clin Endocrinol Metab 84:272-278 (Pubitemid 29036713)
19. Miyazaki Y, Pipek R, Mandarino LJ, DeFronzo RA 2003 Tumor necrosis factor α and insulin resistance in obese type 2 diabetic patients. Int J Obes Relat Metab Disord 27:88-94 (Pubitemid 36152785)
20. Müller S, Martin S, Koenig W, Hanifi-Moghaddam P, Rathmann W, Haastert B, Giani G, Illig T, Thorand B, Kolb H 2002 Impaired glucose tolerance is associated with increased serum concentrations of interleukin 6 and co-regulated acute-phase proteins but not TNF-α or its receptors. Diabetologia 45:805-812
21. Choi KM, Lee J, Lee KW, Seo JA, Oh JH, Kim SG, Kim NH, Choi DS, Baik SH 2004 Comparison of serum concentrations of C-reactive protein, TNF-α, and interleukin 6 between elderly Korean women with normal and impaired glucose tolerance. Diabetes Res Clin Pract 64:99-106 (Pubitemid 38456687)
22. Piemonti L, Calori G, Mercalli A, Lattuada G, Monti P, Garancini MP, Costantino F, Ruotolo G, Luzi L, Perseghin G 2003 Fasting plasma leptin, tumor necrosis factor-α receptor 2, and monocyte chemoattracting protein 1 concentration in a population of glucosetolerant and glucose-intolerant women: impact on cardiovascular mortality. Diabetes Care 26:2883-2889 (Pubitemid 37205563)
23. Wagenknecht LE, Mayer EJ, Rewers M, Haffner S, Selby J, Borok GM, Henkin L, Howard G, Savage PJ, Saad MF, et al. 1995 The insulin resistance atherosclerosis study (IRAS) objectives, design, and recruitment results. Ann Epidemiol 5:464-472
24. 1985 Diabetes mellitus. Report of a WHO Study Group. World Health Organ Tech Rep Ser 727:1-113
25. 1997 Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 20:1183-1197
26. Genuth S, Alberti KG, Bennett P, Buse J, Defronzo R, Kahn R, Kitzmiller J, Knowler WC, Lebovitz H, Lernmark A, Nathan D, Palmer J, Rizza R, Saudek C, Shaw J, Steffes M, Stern M, Tuomilehto J, Zimmet P 2003 Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 26:3160-3167 (Pubitemid 37339514)
27. Bergman RN, Finegood DT, Ader M 1985 Assessment of insulin sensitivity in vivo. Endocr Rev 6:45-86
28. Welch S, Gebhart SS, Bergman RN, Phillips LS 1990 Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects. J Clin Endocrinol Metab 71:1508-1518 (Pubitemid 120032768)
29. Steil GM, Volund A, Kahn SE, Bergman RN 1993 Reduced sample number for calculation of insulin sensitivity and glucose effectiveness from the minimal model. Suitability for use in population studies. Diabetes 42:250-256 (Pubitemid 23045028)
30. Festa A, D'Agostino Jr R, Howard G, Mykkänen L, Tracy RP, Haffner SM 2000 Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 102:42-47 (Pubitemid 30430551)
31. Festa A, Williams K, Tracy RP, Wagenknecht LE, Haffner SM 2006 Progression of plasminogen activator inhibitor-1 and fibrinogen levels in relation to incident type 2 diabetes. Circulation 113:1753-1759 (Pubitemid 43958468)
32. Kleinbaum D, Kupper L, Muller K 1988 Applied regression analysis and other multivariable methods. 2nd ed. Boston: PWS-KENT Publishing; 92
33. Zar J 2010 Biostatistical analysis. 5th ed. Upper Saddle River, NJ: Prentice-Hall; 393-398
34. Ho RC, Davy KP, Hickey MS, Melby CL 2005 Circulating tumor necrosis factor α is higher in non-obese, non-diabetic Mexican Americans compared to non-Hispanic white adults. Cytokine 30:14-21 (Pubitemid 40387351)
35. Hyatt TC, Phadke RP, Hunter GR, Bush NC, Muñoz AJ, Gower BA 2009 Insulin sensitivity in African-American and white women: association with inflammation. Obesity (Silver Spring) 17:276-282
36. Fisher G, Hyatt TC, Hunter GR, Oster RA, Desmond RA, Gower BA 28 April 2011 Markers of inflammation and fat distribution following weight loss in African-American and white women. Obesity (Silver Spring) 10.1038/oby.2011.85
37. Festa A, Hanley AJ, Tracy RP, D'Agostino Jr R, Haffner SM 2003 Inflammation in the prediabetic state is related to increased insulin resistance rather than decreased insulin secretion. Circulation 108: 1822-1830 (Pubitemid 37296091)
38. Haffner SM, D'Agostino Jr R, Mykkänen L, Tracy R, Howard B, Rewers M, Selby J, Savage PJ, Saad MF 1999 Insulin sensitivity in subjects with type 2 diabetes. Relationship to cardiovascular risk factors: the Insulin Resistance Atherosclerosis Study. Diabetes Care 22:562-568 (Pubitemid 29153041)
39. Hotamisligil GS, Shargill NS, Spiegelman BM 1993 Adipose expression of tumor necrosis factor-α: direct role in obesity-linked insulin resistance. Science 259:87-91 (Pubitemid 23036092)
40. Bertin E, Nguyen P, Guenounou M, Durlach V, Potron G, Leutenegger M 2000 Plasma levels of tumor necrosis factor-α (TNF-α) are essentially dependent on visceral fat amount in type 2 diabetic patients. Diabetes Metab 26:178-182 (Pubitemid 30435762)
41. Cartier A, Cote M, Bergeron J, Almeras N, Tremblay A, Lemieux I, Despres JP 2010 Plasma soluble tumour necrosis factor-α receptor 2 is elevated in obesity: specific contribution of visceral adiposity. Clin Endocrinol (Oxf) 72:349-357
42. Kissebah AH, Vydelingum N, Murray R, Evans DJ, Hartz AJ, Kalkhoff RK, Adams PW 1982 Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 54:254-260 (Pubitemid 12006594)
43. Alessi MC, Juhan-Vague I 2006 PAI-1 and the metabolic syndrome: links, causes, and consequences. Arterioscler Thromb Vasc Biol 26: 2200-2207 (Pubitemid 44465712)