메뉴 건너뛰기




Volumn 30, Issue 8, 2014, Pages 1163-1171

Prediction of therapeutic microRNA based on the human metabolic network

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA;

EID: 84898857127     PISSN: 13674803     EISSN: 14602059     Source Type: Journal    
DOI: 10.1093/bioinformatics/btt751     Document Type: Article
Times cited : (9)

References (73)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 2
    • 34347258175 scopus 로고    scopus 로고
    • Quantitative prediction of cellular metabolism with constraint-based models: The COBRA Toolbox
    • Becker, S.A. et al. (2007) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox. Nat. Protoc, 2, 727-738.
    • (2007) Nat. Protoc , vol.2 , pp. 727-738
    • Becker, S.A.1
  • 3
    • 44949225040 scopus 로고    scopus 로고
    • Context-specific metabolic networks are consistent with experiments
    • Becker, S.A. and Palsson, B.O. (2008) Context-specific metabolic networks are consistent with experiments. Plos Comput. Biol., 4, e1000082.
    • (2008) Plos Comput. Biol. , vol.4
    • Becker, S.A.1    Palsson, B.O.2
  • 4
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin, G.A. et al. (2002) Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA, 99, 15524-15529.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1
  • 5
    • 79952830765 scopus 로고    scopus 로고
    • A-enolase: A promising therapeutic and diagnostic tumor target
    • Capello, M. et al. (2011) a-enolase: a promising therapeutic and diagnostic tumor target. FEBS J., 278, 1064-1074.
    • (2011) FEBS J. , vol.278 , pp. 1064-1074
    • Capello, M.1
  • 6
    • 38549117301 scopus 로고    scopus 로고
    • The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases
    • Caspi, R. et al. (2008) The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases. Nucleic Acids Res., 36, D623-D631.
    • (2008) Nucleic Acids Res. , vol.36
    • Caspi, R.1
  • 7
    • 0012959337 scopus 로고    scopus 로고
    • Metabolic flux analysis of cultured hepatocytes exposed to plasma
    • Chan, C. et al. (2003) Metabolic flux analysis of cultured hepatocytes exposed to plasma. Biotechnol. Bioeng., 81, 33-49.
    • (2003) Biotechnol. Bioeng. , vol.81 , pp. 33-49
    • Chan, C.1
  • 8
    • 78049445175 scopus 로고    scopus 로고
    • Drug off-target effects predicted using structural analysis in the context of a metabolic network model
    • Chang, R.L. et al. (2010) Drug off-target effects predicted using structural analysis in the context of a metabolic network model. Plos Comput. Biol., 6, e1000938.
    • (2010) Plos Comput. Biol. , vol.6
    • Chang, R.L.1
  • 9
    • 40749163248 scopus 로고    scopus 로고
    • The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
    • Christofk, H.R. et al. (2008) The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature, 452, 230-233.
    • (2008) Nature , vol.452 , pp. 230-233
    • Christofk, H.R.1
  • 10
    • 70049110173 scopus 로고    scopus 로고
    • Interpreting expression data with metabolic flux models: Predicting mycobacterium tuberculosis mycolic acid production
    • Colijn, C. et al. (2009) Interpreting expression data with metabolic flux models: predicting mycobacterium tuberculosis mycolic acid production. Plos Comput. Biol., 5, e1000489.
    • (2009) Plos Comput. Biol. , vol.5
    • Colijn, C.1
  • 11
    • 37449024702 scopus 로고    scopus 로고
    • The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
    • DeBerardinis, RJ. et al. (2008) The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab., 7, 11-20.
    • (2008) Cell Metab. , vol.7 , pp. 11-20
    • Deberardinis, R.J.1
  • 12
    • 0031194875 scopus 로고    scopus 로고
    • Inverse flux analysis for reduction of acetate excretion in Escherichia coli
    • Delgado, J. and Liao, J.C. (1997) Inverse flux analysis for reduction of acetate excretion in Escherichia coli. Biotechnol. Prog., 13, 361-367.
    • (1997) Biotechnol. Prog. , vol.13 , pp. 361-367
    • Delgado, J.1    Liao, J.C.2
  • 13
    • 33846910173 scopus 로고    scopus 로고
    • Global reconstruction of the human metabolic network based on genomic and bibliomic data
    • Duarte, N.C. et al. (2007) Global reconstruction of the human metabolic network based on genomic and bibliomic data. Proc. Natl Acad. Sci. USA, 104, 1777-1782.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 1777-1782
    • Duarte, N.C.1
  • 14
    • 84898877069 scopus 로고    scopus 로고
    • Predicting selective drug targets in cancer through metabolic networks
    • Folger, O. et al. (2011) Predicting selective drug targets in cancer through metabolic networks. Mol Syst Biol., 7501.
    • (2011) Mol Syst Biol. , pp. 7501
    • Folger, O.1
  • 15
    • 60149095444 scopus 로고    scopus 로고
    • Most mammalian mRNAs are conserved targets of microRNAs
    • Friedman, R.C. et al. (2009) Most mammalian mRNAs are conserved targets of microRNAs. Genome Res., 19, 92-105.
    • (2009) Genome Res. , vol.19 , pp. 92-105
    • Friedman, R.C.1
  • 16
    • 77953471622 scopus 로고    scopus 로고
    • Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice
    • Fritz, V. et al. (2010) Abrogation of de novo lipogenesis by stearoyl-CoA desaturase 1 inhibition interferes with oncogenic signaling and blocks prostate cancer progression in mice. Mol. Cancer Ther., 9, 1740-1754.
    • (2010) Mol. Cancer Ther. , vol.9 , pp. 1740-1754
    • Fritz, V.1
  • 17
    • 48949117194 scopus 로고    scopus 로고
    • Cytotoxic nucleoside analogues: Different strategies to improve their clinical efficacy
    • Galmarini, C.M. et al. (2008) Cytotoxic nucleoside analogues: different strategies to improve their clinical efficacy. Curr. Med. Chem., 15, 1072-1082.
    • (2008) Curr. Med. Chem. , vol.15 , pp. 1072-1082
    • Galmarini, C.M.1
  • 18
    • 34047270440 scopus 로고    scopus 로고
    • Characterization of microRNA expression levels and their biological correlates in human cancer cell lines
    • Gaur, A. et al. (2007) Characterization of microRNA expression levels and their biological correlates in human cancer cell lines. Cancer Res., 67, 2456-2468.
    • (2007) Cancer Res. , vol.67 , pp. 2456-2468
    • Gaur, A.1
  • 19
    • 77956407882 scopus 로고    scopus 로고
    • HepatoNet1: A comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology
    • Gille, C. et al. (2010) HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Mol. Syst. Biol., 6, 411.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 411
    • Gille, C.1
  • 20
    • 83255162659 scopus 로고    scopus 로고
    • An HNF4a-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis
    • Hatziapostolou, M. et al. (2011) An HNF4a-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell, 147, 1233-1247.
    • (2011) Cell , vol.147 , pp. 1233-1247
    • Hatziapostolou, M.1
  • 21
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He, L. et al. (2005) A microRNA polycistron as a potential human oncogene. Nature, 435, 828-833.
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1
  • 22
    • 77956210076 scopus 로고    scopus 로고
    • Inhibition of StearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells
    • Hess, D. et al. (2010) Inhibition of StearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells. Plos One, 5, e11394.
    • (2010) Plos One , vol.5
    • Hess, D.1
  • 23
    • 79959365550 scopus 로고    scopus 로고
    • Elucidation of cellular metabolism via metabolomics and stable-isotope assisted metabolomics
    • Hiller, K. et al. (2011) Elucidation of cellular metabolism via metabolomics and stable-isotope assisted metabolomics. Curr. Pharm. Biotechnol., 12, 1075-1086.
    • (2011) Curr. Pharm. Biotechnol. , vol.12 , pp. 1075-1086
    • Hiller, K.1
  • 24
    • 78751575782 scopus 로고    scopus 로고
    • The role of microRNAs in liver cancer progression
    • Huang, S. and He, X. (2011) The role of microRNAs in liver cancer progression. Br. J. Cancer, 104, 235-240.
    • (2011) Br. J. Cancer , vol.104 , pp. 235-240
    • Huang, S.1    He, X.2
  • 25
    • 79959745257 scopus 로고    scopus 로고
    • Roles of StearoylCoA desaturase-1 in the regulation of cancer cell growth, survival and tumorigenesis
    • Igal, R.A. (2011) Roles of StearoylCoA desaturase-1 in the regulation of cancer cell growth, survival and tumorigenesis. Cancers, 3, 2462-2477.
    • (2011) Cancers , vol.3 , pp. 2462-2477
    • Igal, R.A.1
  • 26
    • 77956290719 scopus 로고    scopus 로고
    • Stearoyl-CoA desaturase-1: A novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer
    • Igal, R.A. (2010) Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer. Carcinogenesis, 31, 1509-1515.
    • (2010) Carcinogenesis , vol.31 , pp. 1509-1515
    • Igal, R.A.1
  • 27
    • 79951536020 scopus 로고    scopus 로고
    • Functional integration of a metabolic network model and expression data without arbitrary thresholding
    • Jensen, P.A. and Papin, J.A. (2011) Functional integration of a metabolic network model and expression data without arbitrary thresholding. Bioinformatics, 27, 541-547.
    • (2011) Bioinformatics , vol.27 , pp. 541-547
    • Jensen, P.A.1    Papin, J.A.2
  • 28
    • 77956417789 scopus 로고    scopus 로고
    • Computational reconstruction of tissue-specific metabolic models: Application to human liver metabolism
    • Jerby, L. et al. (2010) Computational reconstruction of tissue-specific metabolic models: application to human liver metabolism. Mol. Syst. Biol., 6, 401.
    • (2010) Mol. Syst. Biol. , vol.6 , pp. 401
    • Jerby, L.1
  • 29
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson, S.M. et al. (2005) RAS is regulated by the let-7 microRNA family. Cell, 120, 635-647.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1
  • 30
    • 84862195351 scopus 로고    scopus 로고
    • COLT-Cancer: Functional genetic screening resource for essential genes in human cancer cell lines
    • Koh, J.L.Y. et al. (2011) COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines. Nucleic Acids Res., 40, D957-D963.
    • (2011) Nucleic Acids Res. , vol.40
    • Koh, J.L.Y.1
  • 31
    • 66449136951 scopus 로고    scopus 로고
    • Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model
    • Kota, J. et al. (2009) Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell, 137, 1005-1017.
    • (2009) Cell , vol.137 , pp. 1005-1017
    • Kota, J.1
  • 32
    • 34247593034 scopus 로고    scopus 로고
    • Impaired microRNA processing enhances cellular transformation and tumorigenesis
    • Kumar, M.S. et al. (2007) Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat. Genet., 39, 673-677.
    • (2007) Nat. Genet. , vol.39 , pp. 673-677
    • Kumar, M.S.1
  • 33
    • 84863173885 scopus 로고    scopus 로고
    • Computational analysis of mRNA expression profiles identifies microRNA-29a/c as predictor of colorectal cancer early recurrence
    • Kuo, T.Y. et al. (2012) Computational analysis of mRNA expression profiles identifies microRNA-29a/c as predictor of colorectal cancer early recurrence. Plos One, 7, e31587.
    • (2012) Plos One , vol.7
    • Kuo, T.Y.1
  • 34
    • 84862250159 scopus 로고    scopus 로고
    • Liverome: A curated database of liver cancer-related gene signatures with self-contained context information
    • Lee, L. et al. (2011) Liverome: a curated database of liver cancer-related gene signatures with self-contained context information. BMC Genomics, 12, S3.
    • (2011) BMC Genomics , vol.12
    • Lee, L.1
  • 35
    • 50549084147 scopus 로고    scopus 로고
    • Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma
    • Li, W. et al. (2008) Diagnostic and prognostic implications of microRNAs in human hepatocellular carcinoma. Int. J. Cancer, 123, 1616-1622.
    • (2008) Int. J. Cancer , vol.123 , pp. 1616-1622
    • Li, W.1
  • 36
    • 63349099766 scopus 로고    scopus 로고
    • An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer
    • Liang, Y. (2008) An expression meta-analysis of predicted microRNA targets identifies a diagnostic signature for lung cancer. BMC Med. Genomics, 1, 61.
    • (2008) BMC Med. Genomics , vol.1 , pp. 61
    • Liang, Y.1
  • 37
    • 80052258995 scopus 로고    scopus 로고
    • Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
    • Locasale, J.W. et al. (2011) Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nat Genet, 43, 869-874.
    • (2011) Nat Genet , vol.43 , pp. 869-874
    • Locasale, J.W.1
  • 38
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu, J. et al. (2005) MicroRNA expression profiles classify human cancers. Nature, 435, 834-838.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1
  • 39
    • 1642457253 scopus 로고    scopus 로고
    • The effects of alternate optimal solutions in constraint-based genome-scale metabolic models
    • Mahadevan, R. and Schilling, C.H. (2003) The effects of alternate optimal solutions in constraint-based genome-scale metabolic models. Metab. Eng., 5, 264-276.
    • (2003) Metab. Eng. , vol.5 , pp. 264-276
    • Mahadevan, R.1    Schilling, C.H.2
  • 40
    • 20444479428 scopus 로고    scopus 로고
    • C-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell, K.A. et al. (2005) c-Myc-regulated microRNAs modulate E2F1 expression. Nature, 435, 839-843.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1
  • 41
    • 77749320898 scopus 로고    scopus 로고
    • What is flux balance analysis?
    • Orth, J.D. et al. (2010) What is flux balance analysis? Nat. Biotechnol., 28, 245-248.
    • (2010) Nat. Biotechnol. , vol.28 , pp. 245-248
    • Orth, J.D.1
  • 42
    • 79952201306 scopus 로고    scopus 로고
    • Computational identification of miRNAs involved in cancer
    • Oulas, A. et al. (2011) Computational identification of miRNAs involved in cancer. Methods Mol. Biol., 676, 23-41.
    • (2011) Methods Mol. Biol. , vol.676 , pp. 23-41
    • Oulas, A.1
  • 44
    • 70349770739 scopus 로고    scopus 로고
    • Constraints-based genome-scale metabolic simulation for systems metabolic engineering
    • Park, J.M. et al. (2009) Constraints-based genome-scale metabolic simulation for systems metabolic engineering. Biotechnol. Adv., 27, 979-988.
    • (2009) Biotechnol. Adv. , vol.27 , pp. 979-988
    • Park, J.M.1
  • 45
    • 84858790233 scopus 로고    scopus 로고
    • Innovation: Metabolomics: The apogee of the omics trilogy
    • Patti, G.J. et al. (2012) Innovation: Metabolomics: the apogee of the omics trilogy. Nat. Rev. Mol. Cell Biol., 13, 263-269.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 263-269
    • Patti, G.J.1
  • 46
    • 40349094597 scopus 로고    scopus 로고
    • MicroRNA-373 induces expression of genes with complementary promoter sequences
    • Place, R.F. et al. (2008) MicroRNA-373 induces expression of genes with complementary promoter sequences. Proc. Natl Acad. Sci. USA, 105, 1608-1613.
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 1608-1613
    • Place, R.F.1
  • 47
    • 78650996423 scopus 로고    scopus 로고
    • Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis
    • Pollari, S. et al. (2011) Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis. Breast Cancer Res. Treat., 125, 421-430.
    • (2011) Breast Cancer Res. Treat. , vol.125 , pp. 421-430
    • Pollari, S.1
  • 48
    • 37549010761 scopus 로고    scopus 로고
    • MicroRNA-implications for cancer
    • Sassen, S. et al. (2008) MicroRNA-implications for cancer. Virchows Arch., 452, 1-10.
    • (2008) Virchows Arch. , vol.452 , pp. 1-10
    • Sassen, S.1
  • 49
    • 79551662521 scopus 로고    scopus 로고
    • Quantitative prediction of cellular metabolism with constraint-based models: The COBRA Toolbox v2.0
    • Schellenberger, J. et al. (2011) Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0. Nat. Protoc., 6, 1290-1307.
    • (2011) Nat. Protoc. , vol.6 , pp. 1290-1307
    • Schellenberger, J.1
  • 50
    • 36549000754 scopus 로고    scopus 로고
    • NMR-based metabolomics: Translational application and treatment of cancer
    • Serkova, N.J. et al. (2007) NMR-based metabolomics: translational application and treatment of cancer. Curr. Opin. Mol. Ther., 9, 572-585.
    • (2007) Curr. Opin. Mol. Ther. , vol.9 , pp. 572-585
    • Serkova, N.J.1
  • 51
    • 51349092391 scopus 로고    scopus 로고
    • Network-based prediction of human tissue-specific metabolism
    • Shlomi, T. et al. (2008) Network-based prediction of human tissue-specific metabolism. Nat. Biotechnol., 26, 1003-1010.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1003-1010
    • Shlomi, T.1
  • 52
    • 79953661070 scopus 로고    scopus 로고
    • Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg Effect
    • Shlomi, T. et al. (2011) Genome-scale metabolic modeling elucidates the role of proliferative adaptation in causing the Warburg Effect. Plos Comput. Biol, 7, e1002018.
    • (2011) Plos Comput. Biol , vol.7
    • Shlomi, T.1
  • 53
    • 84855466734 scopus 로고    scopus 로고
    • Regulation of Aerobic Glycolysis by microRNAs in Cancer
    • Singh, P.K. et al. (2011) Regulation of Aerobic Glycolysis by microRNAs in Cancer. Mol. Cell Pharmacol., 3, 125-134.
    • (2011) Mol. Cell Pharmacol. , vol.3 , pp. 125-134
    • Singh, P.K.1
  • 54
    • 84870886414 scopus 로고    scopus 로고
    • Mitochondria 'fuel' breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells
    • Sotgia, F. et al. (2012) Mitochondria 'fuel' breast cancer metabolism: fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. Cell Cycle, 11, 4390-4401.
    • (2012) Cell Cycle , vol.11 , pp. 4390-4401
    • Sotgia, F.1
  • 55
    • 38449101948 scopus 로고    scopus 로고
    • Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line
    • Srivastava, S. and Chan, C. (2008) Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnol. Bioeng., 99, 399-410.
    • (2008) Biotechnol. Bioeng. , vol.99 , pp. 399-410
    • Srivastava, S.1    Chan, C.2
  • 57
    • 79961221205 scopus 로고    scopus 로고
    • Metabolic flux analysis and visualization
    • Toya, Y. et al. (2011) Metabolic flux analysis and visualization. J. Proteome Res., 10, 3313-3323.
    • (2011) J. Proteome Res. , vol.10 , pp. 3313-3323
    • Toya, Y.1
  • 58
    • 84898924778 scopus 로고    scopus 로고
    • Glycogen metabolism provides nutritional support to renal cancer cells under conditions of stress and may serve as a marker of response to antiangiogenic therapy with bevacizumab
    • Tsavachidou, D. et al. (2010) Glycogen metabolism provides nutritional support to renal cancer cells under conditions of stress and may serve as a marker of response to antiangiogenic therapy with bevacizumab. AACR Meet. Abstr., 2010, PR12.
    • (2010) AACR Meet. Abstr. , vol.2010
    • Tsavachidou, D.1
  • 59
    • 33644638088 scopus 로고    scopus 로고
    • Synthetic microRNA and double-stranded RNA targeting the 3'-untranslated region of HER-2/neu mRNA inhibit HER-2 protein expression in ovarian cancer cells
    • Tsuda, N. et al. (2005) Synthetic microRNA and double-stranded RNA targeting the 3'-untranslated region of HER-2/neu mRNA inhibit HER-2 protein expression in ovarian cancer cells. Int. J. Oncol., 27, 1299-1306.
    • (2005) Int. J. Oncol. , vol.27 , pp. 1299-1306
    • Tsuda, N.1
  • 60
    • 77953122846 scopus 로고    scopus 로고
    • Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells
    • Tu, S.H. et al. (2010) Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cells. Breast Cancer Res. Treat., 121, 539-553.
    • (2010) Breast Cancer Res. Treat. , vol.121 , pp. 539-553
    • Tu, S.H.1
  • 61
    • 78449291015 scopus 로고    scopus 로고
    • Predicting metabolic fluxes using gene expression differences as constraints
    • Van Berlo, RJ.P. et al. (2011) Predicting metabolic fluxes using gene expression differences as constraints. IEEE/ACM Trans. Comput. Biol. Bioinform., 8, 206-216.
    • (2011) IEEE/ACM Trans. Comput. Biol. Bioinform. , vol.8 , pp. 206-216
    • Van Berlo, R.J.P.1
  • 62
    • 84865169609 scopus 로고    scopus 로고
    • Metabolic pathway alterations that support cell proliferation
    • Vander Heiden, M.G et al. (2012) Metabolic pathway alterations that support cell proliferation. Cold Spring Harb. Symp. Quant. Biol., 76, 325-334.
    • (2012) Cold Spring Harb. Symp. Quant. Biol. , vol.76 , pp. 325-334
    • Vander Heiden, M.G.1
  • 63
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden, M.G. et al. (2009) Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science, 324, 1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1
  • 64
    • 84870933131 scopus 로고    scopus 로고
    • Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE
    • Wang, Y. et al. (2012) Reconstruction of genome-scale metabolic models for 126 human tissues using mCADRE. BMC Syst. Biol., 6, 153.
    • (2012) BMC Syst. Biol. , vol.6 , pp. 153
    • Wang, Y.1
  • 65
    • 0001221508 scopus 로고
    • On respiratory impairment in cancer cells
    • WARBURG, O. (1956a) On respiratory impairment in cancer cells. Science, 124, 269-270.
    • (1956) Science , vol.124 , pp. 269-270
    • Warburg, O.1
  • 66
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • WARBURG, O. (1956b) On the origin of cancer cells. Science, 123, 309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 67
    • 84979279765 scopus 로고    scopus 로고
    • Human metabolic network: Reconstruction, simulation, and applications in systems biology
    • Wu, M. and Chan, C. (2012) Human metabolic network: reconstruction, simulation, and applications in systems biology. Metabolites, 2, 242-253.
    • (2012) Metabolites , vol.2 , pp. 242-253
    • Wu, M.1    Chan, C.2
  • 68
    • 60149084355 scopus 로고    scopus 로고
    • Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance
    • Xin, F. et al. (2009) Computational analysis of microRNA profiles and their target genes suggests significant involvement in breast cancer antiestrogen resistance. Bioinformatics, 25, 430-434.
    • (2009) Bioinformatics , vol.25 , pp. 430-434
    • Xin, F.1
  • 69
    • 80054863354 scopus 로고    scopus 로고
    • Context-specific miRNA regulation network predicts cancer prognosis
    • IEEE, New York, NY
    • Xionghui Zhou et al. (2011) Context-specific miRNA regulation network predicts cancer prognosis. In: 2011 IEEE International Conference on Systems Biology (ISB). IEEE, New York, NY, pp. 225-243.
    • (2011) 2011 IEEE International Conference on Systems Biology (ISB) , pp. 225-243
    • Zhou, X.1
  • 70
    • 84860321700 scopus 로고    scopus 로고
    • Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
    • Ying, H. et al. (2012) Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism. Cell, 149, 656-670.
    • (2012) Cell , vol.149 , pp. 656-670
    • Ying, H.1
  • 71
    • 79959448071 scopus 로고    scopus 로고
    • A novel computational framework for simultaneous integration of multiple types of genomic data to identify microRNA-gene regulatory modules
    • Zhang, S. et al. (2011) A novel computational framework for simultaneous integration of multiple types of genomic data to identify microRNA-gene regulatory modules. Bioinformatics, 27, i401-i409.
    • (2011) Bioinformatics , vol.27
    • Zhang, S.1
  • 72
    • 77954504259 scopus 로고    scopus 로고
    • Comparison and integration of target prediction algorithms for microRNA studies
    • Zhang, Y. and Verbeek, F.J. (2010) Comparison and integration of target prediction algorithms for microRNA studies. J. Integr. Bioinform., 7, 3.
    • (2010) J. Integr. Bioinform. , vol.7 , pp. 3
    • Zhang, Y.1    Verbeek, F.J.2
  • 73
    • 84862581118 scopus 로고    scopus 로고
    • Estrogen receptor alpha interacts with mitochondrial protein HADHB and affects beta-oxidation activity
    • Zhou, Z. et al. (2012) Estrogen receptor alpha interacts with mitochondrial protein HADHB and affects beta-oxidation activity. Mol. Cell. Proteomics, 11, M111.011056.
    • (2012) Mol. Cell. Proteomics , vol.11
    • Zhou, Z.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.